Sonochemical-Assisted Biogenic Synthesis of Theophrasite β-Ni(OH)2 Nanocluster Using Chia Seeds Extract: Characterization and Anticancer Activity
Open accessAbstract
Theophrasite β-Ni(OH)2 nanocluster were fabricated via the sonochemical-assisted biogenic method using chia seeds extract as a reducing and stabilizing agent. The optical and morphological feature of the synthesized nanocluster was characterized using UV-Vis, FTIR, FE-SEM-EDS, HR-TEM, DLS, XPS, and XRD analysis. According to FE-SEM and HR-TEM images of the synthesized materials, β-Ni(OH)2 nanocluster illustrates the hexagonal particle shape with an average size of 5.8 nm, while the EDS results confirm the high purity of the synthesized nanocluster. Moreover, the XRD pattern of the synthesized materials shows typical peaks that match the reference pattern of the Theophrasite form of β-Ni(OH)2 with a hexagonal crystal system. The XPS analysis illustrates that the prepared samples exhibit both Ni2+ and Ni3+ with the predominance of Ni2+ species. Additionally the in-vitro cytotoxic activity of β-Ni(OH)2 nanocluster is tested against the MCF7 cell lines (breast cancer cells). The MTT assay results proved that the synthesized β-Ni(OH)2 nanocluster has potent cytotoxic activity against breast cancer cell lines (IC50: 62.7 μg/mL).
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Extract of chia seeds is employed to synthesize biogenic nanomaterials for therapeutic applications such as anticancer activity, cytotoxicity, and photocatalytic activity.
“In addition, the extract of chia seeds is employed to synthesize biogenic nanomaterials for therapeutic applications such as anticancer activity, cytotoxicity, and photocatalytic activity [154,155].”
From Nutritional and Functional New Perspectives and Potential Health Benefits of Quinoa and Chia Seeds (2023) · cites this paper as [155]
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Nutritional and Functional New Perspectives and Potential Health Benefits of Quinoa and Chia Seeds
Agarwal, A., Rizwana, Tripathi, A. D., Kumar, T., Sharma, K. P., & Patel, S. K. S. (2023) · Antioxidants · doi:10.3390/antiox12071413 · Cited by 135 · see citing works
- Authors
- Hassanin, H. A., & Taha, A.
- Affiliations
- Ain Shams University (EG)
- Al-Neelain University (SD)
- Corresponding author
- Taha, Amel
- Venue
- Nanomaterials
- Publisher
- MDPI AG
- Published
- 2022-06-03
- Volume
- 12
- Issue
- 11
- Pages
- 1919
- ISSN
- 2079-4991 (ISSN-L)
- PMC
- PMC9182536
- OpenAlex
- W4281653490
- Cited by
- 13
- References
- 62
- Citations by year
- 2026: 3 · 2025: 5 · 2024: 2 · 2023: 2 · 2022: 1
- FWCI
- 0.70
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- Nanomaterials (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion)
- Funders
- Scientific Research at King Faisal University (AN000257)
- Topics
- Physical Sciences › Materials Science › Materials Chemistry › Nanoparticles: synthesis and applications
- Physical Sciences › Materials Science › Materials Chemistry › Ultrasound and Cavitation Phenomena
- Physical Sciences › Chemistry › Organic Chemistry › Nanomaterials for catalytic reactions
- Keywords
- nickel hydroxide, green synthesis, anticancer activity, cytotoxicity, MCF-7 cells
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