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Cited by 257

The DOI matches its Crossref record; 123 of the 123 references it cites were found in a registry or an index.

Vitamin D Deficiency and Oral Health: A Comprehensive Review

Open access
Botelho, João, Machado, Vanessa, Proença, Luís, Delgado, Ana Sintra, Mendes, José João·2020·Nutrients
DOI 10.3390/nu12051471
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Abstract

Vitamin D (VD) levels have been gaining growing attention in Oral Health. During growth and adulthood, VD deficiency (VDD) is associated with a wide variety of oral health disorders, and impaired VD synthesis may expedite some of these conditions. In children, severe VDD can induce defective tooth mineralization, resulting in dentin and enamel defects. As a consequence, these defects may increase the risk of the onset and progression of dental caries. Further, VDD has been associated with higher prevalence of periodontitis and gingival inflammation, and several recent preclinical and clinical studies have unveiled potential pathways through which Vitamin D may interact with the periodontium. VDD correction through supplementation may contribute to a successful treatment of periodontitis; however, alveolar bone regeneration procedures performed in baseline VDD patients seem more prone to failure. Vitamin D may also be linked with some oral pathology entities such as certain oral cancers and events of osteonecrosis of the jaw. This review aims to provide comprehensive evidence of how VD levels should be considered to promote good oral health, and to summarize how VDD may hamper oral development and its role in certain oral conditions.

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Metadata

Authors
Botelho, J., Machado, V., Proença, L., Delgado, A. S., & Mendes, J. J.
Venue
Nutrients
Publisher
MDPI AG
Published
2020-05-19
Volume
12
Issue
5
Pages
1471
ISSN
2072-6643 (ISSN-L)
DOI
10.3390/nu12051471
OpenAlex
W3026985456
Cited by
257
References
123
FWCI
16.52
Type
journal article
Language
en
Open access
gold

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CoChat. (2026). Citation check: Vitamin D Deficiency and Oral Health: A Comprehensive Review. https://app.cochat.ai/papers/10.3390/nu12051471
The paper
Botelho, J., Machado, V., Proença, L., Delgado, A. S., & Mendes, J. J. (2020). Vitamin D Deficiency and Oral Health: A Comprehensive Review. Nutrients. https://doi.org/10.3390/nu12051471

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