The DOI matches its Crossref record; 225 of the 225 references it cites were found in a registry or an index.
Is There Such a Thing as “Anti-Nutrients”? A Narrative Review of Perceived Problematic Plant Compounds
Open accessAbstract
Plant-based diets are associated with reduced risk of lifestyle-induced chronic diseases. The thousands of phytochemicals they contain are implicated in cellular-based mechanisms to promote antioxidant defense and reduce inflammation. While recommendations encourage the intake of fruits and vegetables, most people fall short of their target daily intake. Despite the need to increase plant-food consumption, there have been some concerns raised about whether they are beneficial because of the various ‘anti-nutrient’ compounds they contain. Some of these anti-nutrients that have been called into question included lectins, oxalates, goitrogens, phytoestrogens, phytates, and tannins. As a result, there may be select individuals with specific health conditions who elect to decrease their plant food intake despite potential benefits. The purpose of this narrative review is to examine the science of these ‘anti-nutrients’ and weigh the evidence of whether these compounds pose an actual health threat.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
1 retracted
Casini, M. L., Marelli, G., Papaleo, E., Ferrari, A. G., D’Ambrosio, F., & Unfer, V. (2006) · Fertility and Sterility · doi:10.1016/j.fertnstert.2005.09.048 · Cited by 141
RetractedThe chemical diversity and distribution of glucosinolates and isothiocyanates among plants
Fahey, J. W., Zalcmann, A. T., & Talalay, P. (2001) · Phytochemistry · doi:10.1016/s0031-9422(00)00316-2 · Cited by 2,964
Potential Synergy of Phytochemicals in Cancer Prevention: Mechanism of Action
Liu, R. H. (2004) · The Journal of Nutrition · doi:10.1093/jn/134.12.3479s · Cited by 2,276
Tannins and Human Health: A Review
Chung, K.-T., Wong, T. Y., Wei, C.-I., Huang, Y.-W., & Lin, Y. (1998) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408699891274273 · Cited by 1,996
Fahey, J. W., Zhang, Y., & Talalay, P. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.19.10367 · Cited by 1,376
Health-promoting components of fruits and vegetables in the diet.
Liu, R. H. (2013) · Advances in Nutrition · doi:10.3945/an.112.003517 · Cited by 1,310
CALCIUM OXALATE IN PLANTS: Formation and Function
Franceschi, V. R., & Nakata, P. A. (2005) · Annual Review of Plant Biology · doi:10.1146/annurev.arplant.56.032604.144106 · Cited by 1,260
Comparison of Two Diets for the Prevention of Recurrent Stones in Idiopathic Hypercalciuria
Borghi, L., Schianchi, T., Meschi, T., Guerra, A., Allegri, F., Maggiore, U., & Novarini, A. (2002) · New England Journal of Medicine · doi:10.1056/nejmoa010369 · Cited by 1,034
Dinu, M., Abbate, R., Gensini, G. F., Casini, A., & Sofi, F. (2017) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2016.1138447 · Cited by 971
Schlemmer, U., Frølich, W., Prieto, R. M., & Grases, F. (2009) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.200900099 · Cited by 903
Cited by
Biological and pharmacological aspects of tannins and potential biotechnological applications
Melo, L. F. M. D., Aquino-Martins, V. G. D. Q., Silva, A. P. D., Oliveira Rocha, H. A., & Scortecci, K. C. (2023) · Food Chemistry · doi:10.1016/j.foodchem.2023.135645 · Cited by 137
Metadata
- Authors
- Petroski, W., & Minich, D. M.
- Venue
- Nutrients
- Publisher
- MDPI AG
- Published
- 2020-09-24
- Volume
- 12
- Issue
- 10
- Pages
- 2929
- ISSN
- 2072-6643 (ISSN-L)
- OpenAlex
- W3088015161
- Cited by
- 316
- References
- 225
- FWCI
- 8.07
- Type
- journal article
- Language
- en
- Open access
- gold
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Is There Such a Thing as “Anti-Nutrients”? A Narrative Review of Perceived Problematic Plant Compounds. https://app.cochat.ai/papers/10.3390/nu12102929
- The paper
- Petroski, W., & Minich, D. M. (2020). Is There Such a Thing as “Anti-Nutrients”? A Narrative Review of Perceived Problematic Plant Compounds. Nutrients. https://doi.org/10.3390/nu12102929
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
