Nutrition-Based Strategies to Reduce Exercise-Induced Muscle Damage and Soreness
Open accessAbstract
Exercise induced-muscle damage (EIMD) occurs after strenuous and/or novel exercise that involves repeated eccentric contractions [...]
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Some amino-acid derivatives, such as creatine and β-hydroxy-β-methylbutyrate (β-HMB), have the potential to expedite post-exercise recovery and support optimal muscle function in athletes and physically active individuals via synergistic mechanisms.
“some amino-acid derivatives, such as creatine (Kerksick et al. 2018;Barnes 2023), and β-hydroxy-β-methylbutyrate (β-HMB) (Kerksick et al. 2018;Barnes 2023), have the potential to expedite post-exercise recovery and support optimal muscle function in athletes and physically active individuals via synergistic mechanisms.”
From Effect of a Multi-Ingredient Post-Workout Dietary Supplement on Body Composition and Muscle Strength – A Randomized Controlled Trial (2025) · cites this paper as Barnes 2023
In the main text (page unavailable), Barnes lists creatine monohydrate and β-hydroxy β-methylbutyrate among compounds with moderate evidence that may be worth considering for post-exercise recovery. The paper does not say they act through synergistic mechanisms or specifically establish their effects on optimal muscle function in athletes and physically active individuals. (LLM, conf=0.85)
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Cites
Nutritional Compounds to Improve Post-Exercise Recovery
O’Connor, E. B., Mündel, T., & Barnes, M. J. (2022) · Nutrients · doi:10.3390/nu14235069 · Cited by 67 · see citing works
Self-citationLee, M., Ho, C.-S., Hsu, Y.-J., & Huang, C. (2022) · Nutrients · doi:10.3390/nu14214563 · Cited by 54 · see citing works
Ayyadurai, V. A. S., Deonikar, P., & Fields, C. (2023) · Nutrients · doi:10.3390/nu15030733 · Cited by 21 · see citing works
Spoelder, M., Koopmans, L., Hartman, Y., Bongers, C. C. W. G., Schoofs, M. C. A., Eijsvogels, T. M. H., & Hopman, M. T. E. (2023) · Nutrients · doi:10.3390/nu15020342 · Cited by 13 · see citing works
Fraschetti, E. C., Skelly, L. E., Prowting, J. L., Sater, A. A. A., & Josse, A. R. (2022) · Nutrients · doi:10.3390/nu14214532 · Cited by 13 · see citing works
Khemtong, C., Tessitore, A., Jaime, S. J., Gobbi, G., Jensen, J., Yang, A., Kuo, C., & Condello, G. (2022) · Nutrients · doi:10.3390/nu14204331 · Cited by 10 · see citing works
Yeh, T., Lei, T., Barnes, M. J., & Zhang, L. (2022) · Nutrients · doi:10.3390/nu14204339 · Cited by 10 · see citing works
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Puente-Fernández, J., Larumbe-Zabala, E., Roberts, J., & Naclerio, F. (2025) · Journal of Dietary Supplements · doi:10.1080/19390211.2025.2488811 · Cited by 6 · see citing works
“…that some amino-acid derivatives, such as creatine (Kerksick et al. 2018; Barnes 2023), and β -hydroxy- β -methylbutyrate ( β -HMB) (Kerksick et al. 2018; Barnes 2023), have the potential to expedite post-exercise recovery and support optimal muscle function in athletes and physically active…”
Astragalus membranaceus (Huangqi) Supplementation in Sports Training: A Systematic Review
Antonelli, M., & Donelli, D. (2024) · Encyclopedia · doi:10.3390/encyclopedia4010014 · Cited by 6 · see citing works
Sena, M. A. D. B., de Mello, D. B., Ferreira, P. F., Muniz‐Santos, R., Fortes, M. D. S. R., Sales, T. D., Theodoro, D. P., Cameron, L. C., & Pereira, M. (2026) · Journal of Science in Sport and Exercise · doi:10.1007/s42978-025-00349-5 · Cited by 1 · see citing works
Fitrianto, A. T., Prayoga, H. D., Habibie, M., & Fitrian, Z. A. (2023) · JOURNAL SPORT AREA · doi:10.25299/sportarea.2023.vol8(3).14191 · Cited by 1 · see citing works
Effect of Kinesio Taping Application on Exercise-induced Muscle Damage: A Mini Review
Lee, D.-Y., & Kim, J. (2024) · The Asian Journal of Kinesiology · doi:10.15758/ajk.2024.26.2.72
Anti-Inflammatory Nutrition Strategy for Athletes' Performance and Recovery
Banerjee, S., Mamodiya, U., & Auttawetchasakoon, P. (2026) · IGI Global eBooks · doi:10.4018/979-8-3373-9544-9.ch011
- Authors
- Barnes, M. J.
- Affiliations
- Massey University (NZ)
- Corresponding author
- Barnes, Matthew J.
- ORCID
- Barnes, Matthew J.
- Venue
- Nutrients
- Publisher
- MDPI AG
- Published
- 2023-05-29
- Volume
- 15
- Issue
- 11
- Pages
- 2523
- ISSN
- 2072-6643 (ISSN-L)
- PMC
- PMC10255909
- OpenAlex
- W4378650501
- Cited by
- 6
- References
- 7
- Citations by year
- 2026: 2 · 2025: 1 · 2024: 2 · 2023: 1
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- Nutrients (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Rehabilitation › Exercise and Physiological Responses
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Muscle metabolism and nutrition
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Muscle Physiology and Disorders
- Keywords
- exercise-induced muscle damage, delayed onset muscle soreness, eccentric contraction, nutrition, dietary supplementation, muscle recovery
- MeSH terms
- Humans, Muscle Contraction, Pain, Exercise, Muscle, Skeletal
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