The DOI matches its Crossref record; 158 of the 158 references it cites were found in a registry or an index.
Perspectives on Immunoglobulins in Colostrum and Milk
Open accessAbstract
Immunoglobulins form an important component of the immunological activity found in milk and colostrum. They are central to the immunological link that occurs when the mother transfers passive immunity to the offspring. The mechanism of transfer varies among mammalian species. Cattle provide a readily available immune rich colostrum and milk in large quantities, making those secretions important potential sources of immune products that may benefit humans. Immune milk is a term used to describe a range of products of the bovine mammary gland that have been tested against several human diseases. The use of colostrum or milk as a source of immunoglobulins, whether intended for the neonate of the species producing the secretion or for a different species, can be viewed in the context of the types of immunoglobulins in the secretion, the mechanisms by which the immunoglobulins are secreted, and the mechanisms by which the neonate or adult consuming the milk then gains immunological benefit. The stability of immunoglobulins as they undergo processing in the milk, or undergo digestion in the intestine, is an additional consideration for evaluating the value of milk immunoglobulins. This review summarizes the fundamental knowledge of immunoglobulins found in colostrum, milk, and immune milk.
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Cites
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Colostrum Management for Dairy Calves
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Cited by
Breast milk, a source of beneficial microbes and associated benefits for infant health
Lyons, K. E., Ryan, C. A., Dempsey, E. M., Ross, R. P., & Stanton, C. (2020) · Nutrients · doi:10.3390/nu12041039 · Cited by 613
Maternal IgG and IgA Antibodies Dampen Mucosal T Helper Cell Responses in Early Life
Koch, M. A., Reiner, G. L., Lugo, K. A., Kreuk, L. S. M., Stanbery, A. G., Ansaldo, E., Seher, T. D., Ludington, W. B., & Barton, G. M. (2016) · Cell · doi:10.1016/j.cell.2016.04.055 · Cited by 315
Robust and Specific Secretory IgA Against SARS-CoV-2 Detected in Human Milk
Fox, A., Marino, J., Amanat, F., Krammer, F., Hahn-Holbrook, J., Zolla-Pazner, S., & Powell, R. L. (2020) · iScience · doi:10.1016/j.isci.2020.101735 · Cited by 292
A specific gene-microbe interaction drives the development of Crohn’s disease–like colitis in mice
Caruso, R., Mathes, T., Martens, E. C., Kamada, N., Nusrat, A., Inohara, N., & Núñez, G. (2019) · Science Immunology · doi:10.1126/sciimmunol.aaw4341 · Cited by 185
“The low or absent Ig levels at weaning in fostered mice are presumably explained by the fact that maternally derived microbiota-specific Igs in the gut are acquired from breast milk after birth (47, 48), but such Igs are expected to be reduced when neonatal mice switched their diet to solid food by 3 weeks of age.”
BackgroundFrom pre- to postweaning: transformation of the young calf's gastrointestinal tract
Meale, S. J., Chaucheyras-Durand, F., Berends, H., Guan, L. L., & Steele, M. A. (2017) · Journal of Dairy Science · doi:10.3168/jds.2016-12474 · Cited by 163
Metadata
- Authors
- Hurley, W. L., & Theil, P. K.
- Venue
- Nutrients
- Publisher
- MDPI AG
- Published
- 2011-04-14
- Volume
- 3
- Issue
- 4
- Pages
- 442-474
- ISSN
- 2072-6643 (ISSN-L)
- OpenAlex
- W2007454130
- Cited by
- 687
- References
- 158
- FWCI
- 23.28
- Type
- journal article
- Language
- en
- Open access
- gold
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