The DOI matches its Crossref record; 147 of the 147 references it cites were found in a registry or an index.
Bone Tissue Engineering in the Treatment of Bone Defects
Open accessAbstract
Bones play an important role in maintaining exercise and protecting organs. Bone defect, as a common orthopedic disease in clinics, can cause tremendous damage with long treatment cycles. Therefore, the treatment of bone defect remains as one of the main challenges in clinical practice. Today, with increased incidence of bone disease in the aging population, demand for bone repair material is high. At present, the method of clinical treatment for bone defects including non-invasive therapy and invasive therapy. Surgical treatment is the most effective way to treat bone defects, such as using bone grafts, Masquelet technique, Ilizarov technique etc. In recent years, the rapid development of tissue engineering technology provides a new treatment strategy for bone repair. This review paper introduces the current situation and challenges of clinical treatment of bone defect repair in detail. The advantages and disadvantages of bone tissue engineering scaffolds are comprehensively discussed from the aspect of material, preparation technology, and function of bone tissue engineering scaffolds. This paper also summarizes the 3D printing technology based on computer technology, aiming at designing personalized artificial scaffolds that can accurately fit bone defects.
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1 retracted
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Cited by
Si, Y., Li, X., Dong, S., Gao, X., Zhu, Y., Mo, L., Wang, Z., Wang, S., & Zhang, C. (2025) · Bioactive Materials · doi:10.1016/j.bioactmat.2025.08.026 · Cited by 17
“The rapid advancement of bone tissue engineering (BTE) has significantly promoted the development of artificial bone grafting materials [6,7].”
Metadata
- Authors
- Xue, N., Ding, X., Huang, R., Jiang, R., Huang, H., Pan, X., Min, W., Chen, J., Duan, J.-A., Liu, P., & Wang, Y.
- Venue
- Pharmaceuticals
- Publisher
- MDPI AG
- Published
- 2022-07-17
- Volume
- 15
- Issue
- 7
- Pages
- 879
- ISSN
- 1424-8247 (ISSN-L)
- OpenAlex
- W4285732298
- Cited by
- 441
- References
- 147
- FWCI
- 23.75
- Type
- journal article
- Language
- en
- Open access
- gold
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- Xue, N., Ding, X., Huang, R., Jiang, R., Huang, H., Pan, X., Min, W., Chen, J., Duan, J.-A., Liu, P., & Wang, Y. (2022). Bone Tissue Engineering in the Treatment of Bone Defects. Pharmaceuticals. https://doi.org/10.3390/ph15070879
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.