The DOI matches its Crossref record; 47 of the 47 references it cites were found in a registry or an index.
Irrational Use of Medicines—A Summary of Key Concepts
Open accessAbstract
Medicines play an integral part of healthcare delivery. However, they are expensive commodities and account for a significant proportion of overall health expenditure in most countries. Irrational use of medicines is a major challenge facing many health systems across the world. Such practices are likely to lead to poor health delivery that may put patients at risk and result in wastage of scarce resources that could have been used to tackle other pressing health needs. The concept of “rational use of medicine” can at times be confusing and not easily appreciated by patients, healthcare providers, policy makers, or the public, all of whom need to collaborate effectively to address this challenge. In this article, we summarize basic concepts such as rational medicine use, good prescribing and dispensing, and explore some of the factors that contribute to irrational use of medicines as well as potential impacts of such practices. This article has been written with the intention of offering a clear, concise, and easy to understand explanation of basic medicine use concepts for health professionals, patients, policy makers, and the public.
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Cites
The antibiotic resistance crisis: part 1: causes and threats.
Ventola, C. L. (2015) · PubMed · Cited by 4,516
Adverse drug reactions as cause of admission to hospital: prospective analysis of 18 820 patients
Pirmohamed, M., James, S., Meakin, S., Green, C., Scott, A. K., Walley, T. J., Farrar, K., Park, B. K., & Breckenridge, A. M. (2004) · BMJ · doi:10.1136/bmj.329.7456.15 · Cited by 3,230
A systematic review of the associations between dose regimens and medication compliance
Claxton, A. J., Cramer, J., & Pierce, C. (2001) · Clinical Therapeutics · doi:10.1016/s0149-2918(01)80109-0 · Cited by 2,388
Llor, C., & Bjerrum, L. (2014) · Therapeutic Advances in Drug Safety · doi:10.1177/2042098614554919 · Cited by 2,079 · cited 1×
“This can include, for instance, giving 21 days course of an antibiotic for a minor infection that requires just 7 days of treatment, or when an antibiotic is prescribed in the first place for a suspected viral infection [33].”
BackgroundDoctor-patient communication: a review.
Ha, J. F., & Longnecker, N. E. (2010) · PubMed · Cited by 1,347
Doctor Patient Communication: A Review
Begum, T. (2015) · Journal of Bangladesh College of Physicians and Surgeons · doi:10.3329/jbcps.v32i2.26036 · Cited by 1,035
“Best Practice” for Patient-Centered Communication: A Narrative Review
King, A., & Hoppe, R. B. (2013) · Journal of Graduate Medical Education · doi:10.4300/jgme-d-13-00072.1 · Cited by 577
Supporting Patient Autonomy: The Importance of Clinician-patient Relationships
Entwistle, V. A., Carter, S. M., Cribb, A., & McCaffery, K. (2010) · Journal of General Internal Medicine · doi:10.1007/s11606-010-1292-2 · Cited by 540
Spurling, G. K., Mansfield, P. R., Montgomery, B. D., Lexchin, J., Doust, J., Othman, N., & Vitry, A. I. (2010) · PLoS Medicine · doi:10.1371/journal.pmed.1000352 · Cited by 526
Lederberg, J. (2000) · Science · doi:10.1126/science.288.5464.287 · Cited by 521
Research works printed but not linked: 14
- Seiter, A. (2010). A Practical Approach to Pharmaceutical Policy, The World Bank. · DOI
- Shivhare, 2010, Drug hazards and rational use of drugs: A review, J. Chem. Pharm. Res., 2, 106
- Gopalakrishnan, 2014, Standard treatment guidelines in primary healthcare practice, J. Fam. Med. Prim. Care, 3, 424, 10.4103/2249-4863.148134 · doi:10.4103/2249-4863.148134
- World Health Organization (1985, January 22–29). Rational use of drugs: A review of major issues. Proceedings of the Conference of Experts, Nairobi, Kenya.
- May, 2008, Whither ‘rational’ use of drugs?, J. Pharm. Pract. Res., 38, 89, 10.1002/j.2055-2335.2008.tb00808.x · doi:10.1002/j.2055-2335.2008.tb00808.x
- Brahma, 2012, Rational use of drugs and irrational drug combinations, Internet J. Pharmacol., 10, 1
- Halczli, 2013, Medication underdosing and underprescribing: Issues that may contribute to polypharmacy, poor outcomes, Formulary, 48, 194
- Gurbani, 2011, Problems and impact of irrational medicines: Use and tools & interventions to improve medicines use, Pharm. Times, 43, 7
- Lim, 2011, Australian dispensing doctors’ prescribing: Quantitative and qualitative analysis, Med. J. Aust., 195, 172, 10.5694/j.1326-5377.2011.tb03272.x · doi:10.5694/j.1326-5377.2011.tb03272.x
- Wilcock, 2001, Dispensing doctors and non-dispensing doctors—A comparison of their prescribing costs, Int. J. Pharm. Pract., 9, 197, 10.1111/j.2042-7174.2001.tb01049.x · doi:10.1111/j.2042-7174.2001.tb01049.x
- Hobbs, F., and Bradley, C. (1998). How Doctors Choose Drugs, Oxford University Press.
- Davis, 2013, Is there a cure for corporate crime in the drug industry?, BMJ, 346, f755, 10.1136/bmj.f755 · doi:10.1136/bmj.f755
- Rottenkolber, 2011, Adverse drug reactions in Germany: Direct costs of internal medicine hospitalizations, Pharmacoepidemiol. Drug Saf., 20, 626, 10.1002/pds.2118 · doi:10.1002/pds.2118
- Posner, 2011, Generic substitution, Br. J. Clin. Pharmacol., 72, 731, 10.1111/j.1365-2125.2011.03920.x · doi:10.1111/j.1365-2125.2011.03920.x
Cited by
Godman, B., Haque, M., McKimm, J., Abu Bakar, M., Sneddon, J., Wale, J., Campbell, S., Martin, A. P., Hoxha, I., Abilova, V., et al. (2020) · Current Medical Research and Opinion · doi:10.1080/03007995.2019.1700947 · Cited by 171
Medicine Shortages: Gaps Between Countries and Global Perspectives
Acosta, A., Vanegas, E. P., Rovira, J., Godman, B., & Bochenek, T. (2019) · Frontiers in Pharmacology · doi:10.3389/fphar.2019.00763 · Cited by 147
Galappatthy, P., Ranasinghe, P., Liyanage, C. K., Wijayabandara, M. S., Mythily, S., & Jayakody, R. L. (2021) · BMC Pharmacology and Toxicology · doi:10.1186/s40360-021-00535-5 · Cited by 26
Priyadharsini, R. P., Ramasamy, K., & Amarendar, S. (2022) · Journal of Family Medicine and Primary Care · doi:10.4103/jfmpc.jfmpc_527_21 · Cited by 23
Rathinavelu, M., Palani, M., Velavan, V., Rajan, R. A., & Ravishankar, S. (2026) · International Journal of Drug Delivery Technology · doi:10.25258/ijddt.16.41s.15
Metadata
- Authors
- Ofori-Asenso, R., & Agyeman, A.
- Venue
- Pharmacy
- Publisher
- MDPI AG
- Published
- 2016-10-28
- Volume
- 4
- Issue
- 4
- Pages
- 35
- ISSN
- 2226-4787 (ISSN-L)
- OpenAlex
- W2544151593
- Cited by
- 287
- References
- 47
- FWCI
- 7.56
- Type
- journal article
- Language
- en
- Open access
- gold
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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