The DOI matches its Crossref record; 83 of the 83 references it cites were found in a registry or an index.
Microfluidics Integrated Biosensors: A Leading Technology towards Lab-on-a-Chip and Sensing Applications
Open accessAbstract
A biosensor can be defined as a compact analytical device or unit incorporating a biological or biologically derived sensitive recognition element immobilized on a physicochemical transducer to measure one or more analytes. Microfluidic systems, on the other hand, provide throughput processing, enhance transport for controlling the flow conditions, increase the mixing rate of different reagents, reduce sample and reagents volume (down to nanoliter), increase sensitivity of detection, and utilize the same platform for both sample preparation and detection. In view of these advantages, the integration of microfluidic and biosensor technologies provides the ability to merge chemical and biological components into a single platform and offers new opportunities for future biosensing applications including portability, disposability, real-time detection, unprecedented accuracies, and simultaneous analysis of different analytes in a single device. This review aims at representing advances and achievements in the field of microfluidic-based biosensing. The review also presents examples extracted from the literature to demonstrate the advantages of merging microfluidic and biosensing technologies and illustrate the versatility that such integration promises in the future biosensing for emerging areas of biological engineering, biomedical studies, point-of-care diagnostics, environmental monitoring, and precision agriculture.
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Cites
Continuous cultures of fused cells secreting antibody of predefined specificity
KÖHLER, G., & MILSTEIN, C. (1975) · Nature · doi:10.1038/256495a0 · Cited by 17,229
In vitro selection of RNA molecules that bind specific ligands
Ellington, A. D., & Szostak, J. W. (1990) · Nature · doi:10.1038/346818a0 · Cited by 9,812
The origins and the future of microfluidics
Whitesides, G. M. (2006) · Nature · doi:10.1038/nature05058 · Cited by 9,687
Xia, Y., & Whitesides, G. M. (1998) · Annual Review of Materials Science · doi:10.1146/annurev.matsci.28.1.153 · Cited by 4,611
Microfluidics: Fluid physics at the nanoliter scale
Squires, T. M., & Quake, S. R. (2005) · Reviews of Modern Physics · doi:10.1103/revmodphys.77.977 · Cited by 4,379
ELECTRODE SYSTEMS FOR CONTINUOUS MONITORING IN CARDIOVASCULAR SURGERY
Clark, L. C., & Lyons, C. (1962) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1962.tb13623.x · Cited by 3,945
Miniaturized total chemical analysis systems: A novel concept for chemical sensing
Manz, A., Graber, N., & Widmer, H. M. (1990) · Sensors and Actuators B: Chemical · doi:10.1016/0925-4005(90)80209-i · Cited by 3,122
The present and future role of microfluidics in biomedical research
Sackmann, E. K., Fulton, A. L., & Beebe, D. J. (2014) · Nature · doi:10.1038/nature13118 · Cited by 2,995
Formation of droplets and bubbles in a microfluidic T-junction—scaling and mechanism of break-up
Garstecki, P., Fuerstman, M. J., Stone, H. A., & Whitesides, G. M. (2006) · Lab on a Chip · doi:10.1039/b510841a · Cited by 2,339
Electrochemical Biosensors - Sensor Principles and Architectures
Grieshaber, D., MacKenzie, R., Vörös, J., & Reimhult, E. (2008) · Sensors · doi:10.3390/s80314000 · Cited by 2,329
Cited by
Jain, S., Nehra, M., Kumar, R., Dilbaghi, N., Hu, T., Kumar, S., Kaushik, A., & Li, C.-Z. (2021) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2021.113074 · Cited by 357
Smart poultry management: Smart sensors, big data, and the internet of things
Astill, J., Dara, R. A., Fraser, E. D. G., Roberts, B., & Sharif, S. (2020) · Computers and Electronics in Agriculture · doi:10.1016/j.compag.2020.105291 · Cited by 316
Review—Nanostructured Materials-Based Nanosensors
Abdel-Karim, R., Reda, Y., & Abdel-Fattah, A. (2020) · Journal of The Electrochemical Society · doi:10.1149/1945-7111/ab67aa · Cited by 303
Nanoplasmonic sensors for biointerfacial science
Jackman, J. A., Rahim Ferhan, A., & Cho, N.-J. (2017) · Chemical Society Reviews · doi:10.1039/c6cs00494f · Cited by 258
Organophosphorus pesticides: Impacts, detection and removal strategies
Ajiboye, T. O., Oladoye, P. O., Olanrewaju, C. A., & Akinsola, G. O. (2022) · Environmental Nanotechnology, Monitoring & Management · doi:10.1016/j.enmm.2022.100655 · Cited by 118
Metadata
- Authors
- Luka, G., Ahmadi, A., Najjaran, H., Alocilja, E., DeRosa, M., Wolthers, K., Malki, A., Aziz, H., Althani, A., & Hoorfar, M.
- Venue
- Sensors
- Publisher
- MDPI AG
- Published
- 2015-12-01
- Volume
- 15
- Issue
- 12
- Pages
- 30011-30031
- ISSN
- 1424-8220 (ISSN-L)
- OpenAlex
- W2181682338
- Cited by
- 566
- References
- 83
- FWCI
- 12.42
- Type
- journal article
- Language
- en
- Open access
- gold
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- Luka, G., Ahmadi, A., Najjaran, H., Alocilja, E., DeRosa, M., Wolthers, K., Malki, A., Aziz, H., Althani, A., & Hoorfar, M. (2015). Microfluidics Integrated Biosensors: A Leading Technology towards Lab-on-a-Chip and Sensing Applications. Sensors. https://doi.org/10.3390/s151229783
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
