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Cited by 14

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Changes in Inflammatory Cytokines and Irisin in Response to High Intensity Swimming in Adolescent versus Adult Male Swimmers

Sanderson, Malcolm, McKinlay, Brandon J., Theocharidis, Alexandros, Kouvelioti, Rozalia, Falk, Bareket, Klentrou, Panagiota·2020·Sports
DOI 10.3390/sports8120157
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Abstract

Swimming is a popular youth sport that is considered beneficial for cardiovascular fitness. However, the potential inflammatory outcomes of high intensity swimming in younger swimmers are unclear, as is the response of irisin, a myokine released during exercise with anti-inflammatory properties. This study compared the plasma concentrations of interleukins 1-beta (IL-1β), 6 (IL-6), 10 (IL-10), tumor necrosis factor alpha (TNF-α) and irisin in response to intense swimming between adolescent and adult male swimmers. Thirty-two swimmers (16 adolescents, 14 ± 1 years; 16 adults, 21.5 ± 3.1 years) completed a high intensity interval swimming trial. At rest, only TNF-α was higher (33%, p < 0.05) in adolescents compared with adults. There was an overall significant increase in IL-1β from pre- to post-swimming (3% in adolescents, 24% in adults), but no significant interaction. IL-10 significantly increased in both groups (+34% in adolescents, +56% in adults). IL-6 and TNF-α increased significantly (+32% and +26%, respectively) in adults, but not in adolescents (+2% and −9%, respectively). Adults showed a small, but significant decrease in irisin (−5%), with no change in adolescents. The lack of an IL-6, TNF-α and irisin response to intense swimming in adolescent swimmers may suggest a blunted inflammatory and myokine response following high intensity exercise in trained youth.

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Cited by

Metadata

Authors
Sanderson, M., McKinlay, B. J., Theocharidis, A., Kouvelioti, R., Falk, B., & Klentrou, P.
Venue
Sports
Publisher
MDPI AG
Published
2020-12-01
Volume
8
Issue
12
Pages
157
ISSN
2075-4663
DOI
10.3390/sports8120157
Cited by
14
References
3
Language
en
Licence
creativecommons.org/licenses/by/4.0/ (vor)
Funders
  • Natural Sciences and Engineering Research Council of Canada (2015-04424)
  • Mitacs (IT08117)

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