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Cited by 13Suicide and Self-Harm StudiesForensic Toxicology and Drug AnalysisHomicide, Infanticide, and Child Abuse

Suicidal Behavior and Its Relationship with Postmortem Forensic Toxicological Findings

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Collados-Ros, Aurelia, Torres-Sánchez, Carmen, Pérez-Cárceles, María Dolores, Luna, Aurelio, Legaz, Isabel·2022·Toxics
DOI 10.3390/toxics10060319PMC PMC9229491
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Abstract

Suicide affects all sociodemographic levels, age groups, and populations worldwide. The factors that can increase the risk of suicidal tendencies are widely studied. The aim of this study was to analyze the types and combinations of toxics found in fatal suicide victims with different suicide mechanisms. A total of 355 autopsies were retrospectively studied, and 26 toxics were determined and related to mechanisms of suicide. Hanging (55%), drug overdose (22.7%), and jumping from a height (17.8%) were most represented suicide mechanisms with positive toxicology. Hanging was the most represented in men (50.3%; p = 0.019), while jumping from a height was more represented in women (29.7%, p = 0.028). Drugs of abuse were the most frequent toxics found in men (55.5%; p < 0.001), while medicines were the most frequent type found in women (70.3%, p < 0.001). Alcohol, nordiazepam, cocaine, and venlafaxine were the most consumed toxics. Benzodiazepines and venlafaxine were found in suicides involving drug overdose, hanging, and jumping from a height. In conclusion, most suicides were associated with drug abuse in men. Hanging was more represented in men and jumping from a height in women. Alcohol was present in combination with other toxics and medicines. The toxicological analysis is fundamental to understanding consumption patterns and establishing strategies and protocols for detecting and preventing suicide.

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Authors
Collados-Ros, A., Torres-Sánchez, C., Pérez-Cárceles, M. D., Luna, A., & Legaz, I.
Affiliations
  • Universidad de Murcia (ES)
  • Department of Legal and Forensic Medicine, Biomedical Research Institute (IMIB), Regional Campus of International Excellence “Campus Mare Nostrum”, Faculty of Medicine, University of Murcia, 30100 Murcia, Spain
ORCID
Venue
Toxics
Publisher
MDPI AG
Published
2022-06-11
Volume
10
Issue
6
Pages
319
ISSN
2305-6304 (ISSN-L)
DOI
10.3390/toxics10060319
PMC
PMC9229491
OpenAlex
W4282828767
Cited by
13
References
84
Citations by year
2026: 2 · 2025: 3 · 2024: 2 · 2023: 4 · 2022: 2
FWCI
2.51
Type
journal article
Language
en
Open access
Licence
Locations
  • Toxics (publishedVersion, cc-by)
  • PubMed Central (publishedVersion, cc-by)
  • PubMed (publishedVersion)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
  • Hispana (submittedVersion, cc-by)
Funders
UMU ([R-1007/2018])
Topics
  • Social Sciences › Psychology › Clinical Psychology › Suicide and Self-Harm Studies
  • Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Toxicology › Forensic Toxicology and Drug Analysis
  • Social Sciences › Sociology and Political Science › Homicide, Infanticide, and Child Abuse
Keywords
suicide, hanging, drug overdose, forensic toxicology, drug abuse, alcohol, benzodiazepines, venlafaxine, sex differences, suicide prevention

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