Suicidal behavior and alcohol abuse.

Pompili, Maurizio; Serafini, Gianluca; Innamorati, Marco; Dominici, Giovanni; Ferracuti, Stefano; Kotzalidis, Giorgio D.; Serra, Giulia; Girardi, Paolo; Janiri, Luigi; Tatarelli, Roberto; Sher, Leo; Lester, David

doi:10.3390/ijerph7041392

Cited by 477Suicide and Self-Harm StudiesSubstance Abuse Treatment and OutcomesHomicide, Infanticide, and Child Abuse

Suicidal behavior and alcohol abuse.

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Pompili, Maurizio, Serafini, Gianluca, Innamorati, Marco, Dominici, Giovanni, Ferracuti, Stefano, Kotzalidis, Giorgio D., Serra, Giulia, Girardi, Paolo +4 more·2010·International Journal of Environmental Research and Public Health

DOI 10.3390/ijerph7041392PMC PMC2872355

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Abstract

Suicide is an escalating public health problem, and alcohol use has consistently been implicated in the precipitation of suicidal behavior. Alcohol abuse may lead to suicidality through disinhibition, impulsiveness and impaired judgment, but it may also be used as a means to ease the distress associated with committing an act of suicide. We reviewed evidence of the relationship between alcohol use and suicide through a search of MedLine and PsychInfo electronic databases. Multiple genetically-related intermediate phenotypes might influence the relationship between alcohol and suicide. Psychiatric disorders, including psychosis, mood disorders and anxiety disorders, as well as susceptibility to stress, might increase the risk of suicidal behavior, but may also have reciprocal influences with alcohol drinking patterns. Increased suicide risk may be heralded by social withdrawal, breakdown of social bonds, and social marginalization, which are common outcomes of untreated alcohol abuse and dependence. People with alcohol dependence or depression should be screened for other psychiatric symptoms and for suicidality. Programs for suicide prevention must take into account drinking habits and should reinforce healthy behavioral patterns.

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Mental flexibility can be affected by variables that impact on cognitive functioning, such as substance abuse or certain physiological states.
“Mental flexibility can be affected by variables that impact on cognitive functioning, such as substance abuse or certain physiological states (Pompili et al., 2010).”
From The Psychological Pathway to Suicide Attempts: A Strategy of Control Without Awareness (2021) · cites this paper as Pompili et al., 2010
The section on proposed psychological mechanisms says alcohol intoxication can produce cognitive constriction—narrowed attention that limits perceived solutions—which supports the substance-abuse part of the claim. The cited paper does not establish the broader claim about mental flexibility being affected by certain physiological states. (LLM, conf=0.83)
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Research works printed but not linked: 1

[26]Institute of Medicine of the National Academies Reducing Suicide A National Imperative The National Academies Press Washington, DC, USA 2002

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“…have a substantial negative impact on development and school, social, and health functioning (Green, McGinnity, Meltzer, Ford, & Goodman, 2005; Pompili et al., 2010), present a risk for ongoing mental health problems (Copeland, Angold, Shanahan, & Costello, 2014) and bring signiﬁcant social…”
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“This is particularly crucial since individual circumstances can affect the influence of risk factors on suicidal behavior (Pompili, 2018), and the relationship between risk factors and suicidal behavior is complex (Pompili et al., 2010).”
Background
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Authors: Pompili, M., Serafini, G., Innamorati, M., Dominici, G., Ferracuti, S., Kotzalidis, G. D., Serra, G., Girardi, P., Janiri, L., Tatarelli, R., Sher, L., & Lester, D.
Affiliations: Harvard University (US)
Azienda Ospedaliera Sant'Andrea (IT)
Department of Neuroscience, Mental Health and Sensory Functions, Suicide Prevention Center, Sant’Andrea Hospital, Sapienza University of Rome, Rome 00189, Italy
Università Cattolica del Sacro Cuore (IT)
Columbia University (US)
Stockton University (US)
Corresponding author: Pompili, Maurizio
ORCID: Pompili, Maurizio
Serafini, Gianluca
Innamorati, Marco
Dominici, Giovanni
Ferracuti, Stefano
Serra, Giulia
Girardi, Paolo
Janiri, Luigi
Tatarelli, Roberto
Sher, Leo
Lester, David
Venue: International Journal of Environmental Research and Public Health
Publisher: MDPI AG
Published: 2010-03-29
Volume: 7
Issue: 4
Pages: 1392-1431
ISSN: 1660-4601 (ISSN-L)
DOI: 10.3390/ijerph7041392
PMC: PMC2872355
OpenAlex: W2138744406
Cited by: 477
References: 294
Citations by year: 2026: 20 · 2025: 26 · 2024: 36 · 2023: 46 · 2022: 42 · 2021: 60 · 2020: 58 · 2019: 32 · 2018: 25 · 2017: 35 · 2016: 30 · 2015: 27 · 2014: 13 · 2013: 11 · 2012: 7
FWCI: 9.11
Type: journal article
Language: en
Open access: gold
doi.org
Licence: cc-by
creativecommons.org/licenses/by/3.0/ (vor)
Locations: International Journal of Environmental Research and Public Health (publishedVersion, cc-by)
PubMed Central (publishedVersion, cc-by)
PubMed (publishedVersion)
RePEc: Research Papers in Economics (submittedVersion)
DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion)
CINECA IRIS Institutial Research Information System (University of Genoa) (submittedVersion)
IRIS Research product catalog (Sapienza University of Rome) (submittedVersion)
PubliCatt (Università Cattolica del Sacro Cuore) (submittedVersion, other-oa)
Topics: Social Sciences › Psychology › Clinical Psychology › Suicide and Self-Harm Studies
Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
Social Sciences › Sociology and Political Science › Homicide, Infanticide, and Child Abuse
Keywords: suicidal behavior, alcohol abuse, alcoholism, suicide risk factors, disinhibition, impulsivity, impaired judgment, psychiatric comorbidity, psychosis, mood disorders, anxiety disorders, stress vulnerability, social withdrawal, social marginalization, depression, suicide risk screening, suicide prevention, alcohol use patterns
MeSH terms: Alcoholism, Female, Humans, Male, Risk Factors, Suicide

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