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Membranous Replication Factories Induced by Plus-Strand RNA Viruses
Open accessAbstract
In this review, we summarize the current knowledge about the membranous replication factories of members of plus-strand (+) RNA viruses. We discuss primarily the architecture of these complex membrane rearrangements, because this topic emerged in the last few years as electron tomography has become more widely available. A general denominator is that two “morphotypes” of membrane alterations can be found that are exemplified by flaviviruses and hepaciviruses: membrane invaginations towards the lumen of the endoplasmatic reticulum (ER) and double membrane vesicles, representing extrusions also originating from the ER, respectively. We hypothesize that either morphotype might reflect common pathways and principles that are used by these viruses to form their membranous replication compartments.
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The SREBP pathway — insights from insigs and insects
Rawson, R. B. (2003) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm1174 · Cited by 323
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Snijder, E. J., Limpens, R. W. A. L., de Wilde, A. H., de Jong, A. W. M., Zevenhoven-Dobbe, J. C., Maier, H. J., Faas, F. F. G. A., Koster, A. J., & Bárcena, M. (2020) · PLOS Biology · doi:10.1371/journal.pbio.3000715 · Cited by 477
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Metadata
- Authors
- Romero-Brey, I., & Bartenschlager, R.
- Venue
- Viruses
- Publisher
- MDPI AG
- Published
- 2014-07-22
- Volume
- 6
- Issue
- 7
- Pages
- 2826-2857
- ISSN
- 1999-4915 (ISSN-L)
- OpenAlex
- W2083901349
- Cited by
- 275
- References
- 1
- FWCI
- 10.88
- Type
- journal article
- Language
- en
- Open access
- gold
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
