Using machine intelligence to uncover Alzheimer’s disease progression heterogeneity

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2016 Alzheimer's disease facts and figures

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The GeneMANIA prediction server: Biological network integration for gene prioritization and predicting gene function

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Meta-Analysis of 74,046 Individuals Identifies 11 New Susceptibility Loci for Alzheimer’s Disease

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Oxidative Medicine and Cellular Longevity

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2020 Alzheimer's disease facts and figures

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Alzheimer’s disease drug-development pipeline: Few candidates, frequent failures

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Gene-Wide Analysis Detects Two New Susceptibility Genes for Alzheimer's Disease

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Multimodal classification of Alzheimer's disease and mild cognitive impairment

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Sodium oligomannate therapeutically remodels gut microbiota and suppresses gut bacterial amino acids-shaped neuroinflammation to inhibit Alzheimer’s disease progression

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Review Article: Genetics of Alzheimer Disease

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Recent global trends in the prevalence and incidence of dementia, and survival with dementia

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The genetic landscape of Alzheimer disease: clinical implications and perspectives

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Is Alzheimer's disease a neurodegenerative or a vascular disorder? Data, dogma, and dialectics

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Therapeutics of Alzheimer's disease: Past, present and future

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Alzheimer's disease drug development pipeline: 2018

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Multi-modal multi-task learning for joint prediction of multiple regression and classification variables in Alzheimer's disease

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Considering sex and gender in Alzheimer disease and other dementias

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Current understanding of metal ions in the pathogenesis of Alzheimer’s disease

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Autophagy and Alzheimer’s Disease: From Molecular Mechanisms to Therapeutic Implications

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Complex Inhibitory Effects of Nitric Oxide on Autophagy

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Molecular Basis of Familial and Sporadic Alzheimer's Disease

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Predicting Future Clinical Changes of MCI Patients Using Longitudinal and Multimodal Biomarkers

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Phosphodiesterases as Therapeutic Targets for Alzheimer's Disease

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Presenilin-1 mutations and Alzheimer’s disease.

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Vascular Basis of Alzheimer's Pathogenesis

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UMAP reveals cryptic population structure and phenotype heterogeneity in large genomic cohorts

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Insulin-like growth factor-1 and risk of Alzheimer dementia and brain atrophy

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Neuronal IGF‐1 resistance reduces Aβ accumulation and protects against premature death in a model of Alzheimer's disease

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Mitochondrial genes are altered in blood early in Alzheimer's disease

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The BTB and CNC Homology 1 (BACH1) Target Genes Are Involved in the Oxidative Stress Response and in Control of the Cell Cycle

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Multifactorial Hypothesis and Multi-Targets for Alzheimer’s Disease

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Genomic variants, genes, and pathways of Alzheimer's disease: An overview

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Gene-environment interactions in Alzheimer's disease: A potential path to precision medicine

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The Role of IGF-1 Receptor and Insulin Receptor Signaling for the Pathogenesis of Alzheimers Disease: From Model Organisms to Human Disease

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Getting to NO Alzheimer’s Disease: Neuroprotection versus Neurotoxicity Mediated by Nitric Oxide

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Review: Insights into molecular mechanisms of disease in neurodegeneration with brain iron accumulation: unifying theories

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Novel Phosphodiesterase Inhibitors for Cognitive Improvement in Alzheimer’s Disease

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Impact of Gender Differences on the Outcome of Alzheimer’s Disease

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The vascular contribution to Alzheimer's disease

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PRECISION MEDICINE - THE GOLDEN GATE FOR DETECTION, TREATMENT AND PREVENTION OF ALZHEIMER’S DISEASE

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40 YEARS of IGF1: IGF1: the Jekyll and Hyde of the aging brain

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Mutations in SLC33A1 Cause a Lethal Autosomal-Recessive Disorder with Congenital Cataracts, Hearing Loss, and Low Serum Copper and Ceruloplasmin

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The identification of cognitive subtypes in Alzheimer's disease dementia using latent class analysis

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Identification of Differentially Expressed Genes through Integrated Study of Alzheimer’s Disease Affected Brain Regions

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Heterogeneity of Alzheimer’s disease: consequence for drug trials?

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Functional Characterization of the GUCY1A3 Coronary Artery Disease Risk Locus

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Sex differences in Alzheimer’s disease: Understanding the molecular impact

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Nonparametric Statistics

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Could Alzheimer’s Disease Originate in the Periphery and If So How So?

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The Alzheimer’s disease transcriptome mimics the neuroprotective signature of IGF-1 receptor-deficient neurons

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The Role of Genetics in Advancing Precision Medicine for Alzheimer’s Disease—A Narrative Review

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The Spleen Tyrosine Kinase (Syk) Regulates Alzheimer Amyloid-β Production and Tau Hyperphosphorylation

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Progress in Polygenic Composite Scores in Alzheimer’s and Other Complex Diseases

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Prediction of Conversion from Mild Cognitive Impairment to Alzheimer's Disease Using MRI and Structural Network Features

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Ensemble Learning: Pattern Classification Using Ensemble Methods

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Back to the future: Alzheimer's disease heterogeneity revisited

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Systems Biology Methods for Alzheimer’s Disease Research Toward Molecular Signatures, Subtypes, and Stages and Precision Medicine: Application in Cohort Studies and Trials

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Phosphodiesterase 5 inhibitors as novel agents for the treatment of Alzheimer’s disease

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Revealing Alzheimer’s disease genes spectrum in the whole-genome by machine learning

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Alzheimer’s disease pathological lesions activate the spleen tyrosine kinase

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Molecular targets and therapeutic interventions for iron induced neurodegeneration

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Molecular differences in Alzheimer's disease between male and female patients determined by integrative network analysis

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Neuregulin in Health and Disease

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Transcriptional Analysis Reveals Distinct Subtypes in Amyotrophic Lateral Sclerosis: Implications for Personalized Therapy

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Prominent Non-Memory Deficits in Alzheimer’s Disease Are Associated with Faster Disease Progression

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Proteolytic Processing of Neuregulin 2

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Microarray Analysis of Gene Expression Changes in Neuroplastin 65-Knockout Mice: Implications for Abnormal Cognition and Emotional Disorders

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Exploring Alzheimer’s Disease Molecular Variability via Calculation of Personalized Transcriptional Signatures

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Genetics in Vascular Dementia

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A Qualitative Analysis Based on Relative Expression Orderings Identifies Transcriptional Subgroups for Alzheimer’s Disease

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Next-Gen AI for Disease Definition, Patient Stratification, and Placebo EffectPreprint

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SYSTEMIC OVEREXPRESSION OF AT-1/SLC33A1 CAUSES A PROGERIA-LIKE PHENOTYPE

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Exploiting machine learning models to identify novel Alzheimer’s disease biomarkers and potential targets

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A review and analysis of key biomarkers in Alzheimer’s disease

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Machine learning hypothesis-generation for patient stratification and target discovery in rare disease: our experience with Open Science in ALS

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Single‐cell sequencing of entorhinal cortex reveals widespread disruption of neuropeptide networks in Alzheimer's disease

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Evaluation of postmortem microarray data in bipolar disorder using traditional data comparison and artificial intelligence reveals novel gene targets

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Curation and validation of electronic medical record-based dementia diagnoses in the VA Million Veteran Program

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Shattering cancer with quantum machine learning: A preview

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Small patient datasets reveal genetic drivers of non-small cell lung cancer subtypes using machine learning for hypothesis generation

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Respondents of health survey powered by the innovative NURO app exhibit correlations between exercise frequencies and diet habits, and between stress levels and sleep wellness

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Classification of preclinical markers in Alzheimer's disease via WiSARD classifier

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Small Patient Datasets Reveal Genetic Drivers of Non-Small Cell Lung Cancer Subtypes Using a Novel Machine Learning ApproachPreprint

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Molecular Subtyping of Alzheimer's Disease with Mixed Pathology from a Single Nucleus/Cell Transcriptomics Atlas

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Learning the progression and clinical subtypes of Alzheimer's disease from longitudinal clinical dataPreprint

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Integrative machine-learning on high-throughput human data identifies age-specific hallmarks of Alzheimer’s disease

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Identifying progression subphenotypes of Alzheimer's disease from large-scale electronic health records with machine learning

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Unified epigenomic, transcriptomic, proteomic, and metabolomic taxonomy of Alzheimer's disease progression and heterogeneity

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