The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Role of the intestinal barrier in inflammatory bowel disease
Open accessAbstract
A critical function of the intestinal mucosa is to form a barrier that separates luminal contents from the interstitium. The single layer of intestinal epithelial cells (IECs) serves as a dynamic interface between the host and its environment. Cell polarity and structural properties of the epithelium is complex and is important in the development of epithelial barrier function. Epithelial cells associate with each other via a series of intercellular junctions. The apical most intercellular junctional complex referred to as the Apical Junction Complex (AJC) is important in not only cell-cell recognition, but also in the regulation of paracellular movement of fluid and solutes. Defects in the intestinal epithelial barrier function have been observed in a number of intestinal disorders such as inflammatory bowel disease (IBD). It is now becoming evident that an aberrant epithelial barrier function plays a central role in the pathophysiology of IBD. Thus, a better understanding of the intestinal epithelial barrier structure and function in healthy and disease states such as IBD will foster new ideas for the development of therapies for such chronic disorders.
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Cites
Takeda, K., Kaisho, T., & Akira, S. (2003) · Annual Review of Immunology · doi:10.1146/annurev.immunol.21.120601.141126 · Cited by 6,143
Gumbiner, B., Stevenson, B., & Grimaldi, A. (1988) · The Journal of cell biology · doi:10.1083/jcb.107.4.1575 · Cited by 799
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Kelly, J. R., Kennedy, P. J., Cryan, J. F., Dinan, T. G., Clarke, G., & Hyland, N. P. (2015) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2015.00392 · Cited by 1,110
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Steck, N., Hoffmann, M., Sava, I. G., Kim, S. C., Hahne, H., Tonkonogy, S. L., Mair, K., Krueger, D., Pruteanu, M., Shanahan, F., et al. (2011) · Gastroenterology · doi:10.1053/j.gastro.2011.05.035 · Cited by 343
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Tumor suppressor scribble regulates assembly of tight junctions in the intestinal epithelium
Ivanov, A. I., Young, C., Beste, K. D., Capaldo, C. T., Humbert, P. O., Brennwald, P., Parkos, C. A., & Nusrat, A. (2010) · The American Journal of Pathology · doi:10.2353/ajpath.2010.090220 · Cited by 73
Self-citationLuminal Cathepsin G and Protease-Activated Receptor 4
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Zhao, H., Yan, R., Zhou, X., Ji, F., & Zhang, B. (2016) · International Immunopharmacology · doi:10.1016/j.intimp.2016.07.020 · Cited by 61
Metadata
- Authors
- Laukoetter, M. G., Nava, P., & Nusrat, A.
- Venue
- World Journal of Gastroenterology
- Publisher
- Baishideng Publishing Group Inc.
- Published
- 2008
- Volume
- 14
- Issue
- 3
- Pages
- 401
- ISSN
- 1007-9327 (ISSN-L)
- OpenAlex
- W2072138444
- Cited by
- 300
- References
- 2
- FWCI
- 11.95
- Type
- journal article
- Language
- en
- Open access
- hybrid
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
