Cited by 266Gastrointestinal motility and disordersInfant Health and DevelopmentGut microbiota and health

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Irritable bowel syndrome: A clinical review

Open access

Soares, Rosa LS·2014·World Journal of Gastroenterology

DOI 10.3748/wjg.v20.i34.12144PMC PMC4161800

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Abstract

Irritable bowel syndrome (IBS) remains a clinical challenge in the 21(st) century. It's the most commonly diagnosed gastrointestinal condition and also the most common reason for referral to gastroenterology clinics. Its can affect up to one in five people at some point in their lives, and has a significantly impact of life quality and health care utilization. The prevalence varies according to country and criteria used to define IBS. Various mechanisms and theories have been proposed about its etiology, but the biopsychosocial model is the most currently accepted for IBS. The complex of symptoms would be the result of the interaction between psychological, behavioral, psychosocial and environmental factors. The diagnosis of IBS is not confirmed by a specific test or structural abnormality. It is made using criteria based on clinical symptoms such as Rome criteria, unless the symptoms are thought to be atypical. Today the Rome Criteria III is the current gold-standard for the diagnoses of IBS. Secure positive evidence of IBS by means of specific disease marker is currently not possible and cannot be currently recommended for routine diagnosis. There is still no clinical evidence to recommend the use of biomarkers in blood to diagnose IBS. However, a number of different changes in IBS patients were demonstrated in recent years, some of which can be used in the future as a diagnostic support. IBS has no definitive treatment but could be controlled by non-pharmacologic management eliminating of some exacerbating factors such certain drugs, stressor conditions and changes in dietary habits.The traditional pharmacologic management of IBS has been symptom based and several drugs have been used. However, the cornerstone of its therapy is a solid patient physician relationship. This review will provide a summary of pathophysiology, diagnostic criteria and current and emerging therapies for IBS.

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Items 201–271 of 271

Increased visceral sensitivity in Giardia‐induced postinfectious irritable bowel syndrome and functional dyspepsia. Effect of the 5HT3‐antagonist ondansetron
Dizdar, V., Gilja, O. H., & Hausken, T. (2007) · Neurogastroenterology & Motility · doi:10.1111/j.1365-2982.2007.00988.x · Cited by 89
Ambulatory 24-Hour Jejunal Motility in Diarrhea-Predominant Irritable Bowel Syndrome
Schmidt, T., Hackelsberger, N., Widmer, R., Meisel, C., Pfeiffer, A., & Kaess, H. (1996) · Scandinavian Journal of Gastroenterology · doi:10.3109/00365529609009131 · Cited by 88
Is a negative colonoscopy associated with reassurance or improved health-related quality of life in irritable bowel syndrome?
Spiegel, B. M. R., Gralnek, I. M., Bolus, R., Chang, L., Dulai, G. S., Naliboff, B., & Mayer, E. A. (2005) · Gastrointestinal Endoscopy · doi:10.1016/j.gie.2005.08.016 · Cited by 87
Epidemiologic study of the irritable bowel syndrome in Beijing: stratified randomized study by cluster sampling.
Pan, G., Lu, S., Ming, K., Han, S., Guo, H., & Fang, X. (2000) · PubMed · Cited by 87
Irritable Bowel Syndrome and Co-morbid Gastrointestinal and Extra-gastrointestinal Functional Syndromes
Sperber, A. D., & Dekel, R. (2010) · Journal of Neurogastroenterology and Motility · doi:10.5056/jnm.2010.16.2.113 · Cited by 85
A History of Abuse in Community Subjects with Irritable Bowel Syndrome and Functional Dyspepsia: The Role of Other Psychosocial Variables
Koloski, N. A., Talley, N. J., & Boyce, P. M. (2005) · Digestion · doi:10.1159/000087722 · Cited by 84
Mucosal Permeability and Immune Activation as Potential Therapeutic Targets of Probiotics in Irritable Bowel Syndrome
Barbara, G., Zecchi, L., Barbaro, M. R., Cremon, C., Bellacosa, L., Marcellini, M. M., GIORGIO, R. D., Corinaldesi, R., & Stanghellini, V. (2012) · Journal of Clinical Gastroenterology · doi:10.1097/mcg.0b013e318264e918 · Cited by 82
Basic Pathophysiologic Mechanisms in Irritable Bowel Syndrome
Mayer, E. A., Naliboff, B. D., & Chang, L. (2001) · Digestive Diseases · doi:10.1159/000050682 · Cited by 81
Prevalence, Sociodemography, and QualitLife of Older Versus Younger Patients with Irritable Bowel Syndrome: A Population-Based Study
Minocha, A., Johnson, W. D., Abell, T., & Wigington, W. C. (2006) · Digestive Diseases and Sciences · doi:10.1007/s10620-006-3153-8 · Cited by 80
Comparison of Lactulose and Glucose Breath Test for Diagnosis of Small Intestinal Bacterial Overgrowth in Patients with Irritable Bowel Syndrome
Rana, S., Sharma, S., Kaur, J., Sinha, S. K., & Singh, K. (2012) · Digestion · doi:10.1159/000336174 · Cited by 80
Advances in Imaging the Brain–Gut Axis: Functional Gastrointestinal Disorders
Tillisch, K., & Labus, J. S. (2010) · Gastroenterology · doi:10.1053/j.gastro.2010.12.014 · Cited by 79
Utility of a Rapid Fecal Latex Agglutination Test Detecting the Neutrophil Protein, Lactoferrin, for Diagnosing Inflammatory Causes of Chronic Diarrhea
Fine, K. D., Ogunji, F., George, J., Niehaus, M. D., & Guerrant, R. L. (1998) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.1998.413_l.x · Cited by 74
Gastrointestinal Symptoms After Infectious Diarrhea: A Five-Year Follow-Up in a Swedish Cohort of Adults
Törnblom, H., Holmvall, P., Svenungsson, B., & Lindberg, G. (2007) · Clinical Gastroenterology and Hepatology · doi:10.1016/j.cgh.2007.01.007 · Cited by 70
Idiopathic bile acid malabsorption: qualitative and quantitative clinical features and response to cholestyramine
Sinha, L., Liston, R., Testa, H. J., & Moriarty, K. J. (1998) · Alimentary Pharmacology & Therapeutics · doi:10.1046/j.1365-2036.1998.00388.x · Cited by 69
Questioning the Bacterial Overgrowth Hypothesis of Irritable Bowel Syndrome: An Epidemiologic and Evolutionary Perspective
Spiegel, B. M. R. (2011) · Clinical Gastroenterology and Hepatology · doi:10.1016/j.cgh.2011.02.030 · Cited by 67
Towards a definition of comorbidity in the light of clinical complexity
Bonavita, V., & Simone, R. D. (2008) · Neurological Sciences · doi:10.1007/s10072-008-0898-1 · Cited by 64
Treating irritable bowel syndrome: overview, perspective and future therapies
Camilleri, M. (2004) · British Journal of Pharmacology · doi:10.1038/sj.bjp.0705741 · Cited by 64
Irritable Bowel Syndrome and Health-Related Quality of Life: A Population-Based Study in Calgary, Alberta
Li, F. X., Patten, S. B., Hilsden, R. J., & Sutherland, L. R. (2003) · Canadian Journal of Gastroenterology · doi:10.1155/2003/706891 · Cited by 62
Suppression of HTLV-1 replication by Tax-mediated rerouting of the p13 viral protein to nuclear speckles
Andresen, V., Pise-Masison, C. A., Sinha-Datta, U., Bellon, M., Valeri, V. W., Parks, R. W., Cecchinato, V., Fukumoto, R., Nicot, C., & Franchini, G. (2011) · Blood · doi:10.1182/blood-2010-06-293340 · Cited by 61
Psychological factors in the irritable bowel syndrome.
Solmaz, M., Kavuk, I., & Sayar, K. (2003) · PubMed · Cited by 60
How does comorbidity affect cost of health care in patients with irritable bowel syndrome? A cohort study in general practice
Johansson, P. A., Farup, P. G., Bracco, A., & Vandvik, P. O. (2010) · BMC Gastroenterology · doi:10.1186/1471-230x-10-31 · Cited by 60
Postinfective Diarrhoea and Bile Acid Malabsorption
Niaz, S. K., Sandrasegaran, K., Renny, F. H., & Jones, B. J. M. (1997) · Journal of the Royal College of Physicians of London · doi:10.1016/s0035-8819(25)00270-3 · Cited by 59
A single-blind trial of reflexology for irritable bowel syndrome.
Tovey, P. (2002) · Europe PMC (PubMed Central) · Cited by 59
Faecal lactoferrin – a novel test to differentiate between the irritable and inflamed bowel?
SIDHU, R., WILSON, P., Wright, A. W. E., Yau, C. W., D'Cruz, F., Foye, L., Morley, S. R., Lobo, A., McAlindon, M. E., & Sanders, D. S. (2010) · Alimentary Pharmacology & Therapeutics · doi:10.1111/j.1365-2036.2010.04306.x · Cited by 57
Scintigraphic Biomarkers for Colonic Dysmotility
Camilleri, M. (2010) · Clinical Pharmacology & Therapeutics · doi:10.1038/clpt.2010.23 · Cited by 54
Treatment of irritable bowel syndrome with osteopathy: Results of a randomized controlled pilot study
Hundscheid, H. W., Pepels, M. J. A. E., Engels, L. G. J. B., & Loffeld, R. J. L. F. (2006) · Journal of Gastroenterology and Hepatology · doi:10.1111/j.1440-1746.2006.04741.x · Cited by 54
Visceral hypersensitivity following cold water intake in subjects with irritable bowel syndrome
Zuo, X. L., Li, Y. Q., Shi, L., Lv, G.-P., Kuang, R. G., Lu, X. F., Li, J. M., & Desmond, P. V. (2006) · Journal of Gastroenterology · doi:10.1007/s00535-005-1766-x · Cited by 54
Prevalence of irritable bowel syndrome in a multi‐ethnic Asian population
Rajendra, S., & Alahuddin, S. (2004) · Alimentary Pharmacology & Therapeutics · doi:10.1111/j.1365-2036.2004.01891.x · Cited by 53
Repetitive rectal painful distention induces rectal hypersensitivity in patients with irritable bowel syndrome
Nozu, T., Kudaira, M., Kitamori, S., & Uehara, A. (2006) · Journal of Gastroenterology · doi:10.1007/s00535-005-1748-z · Cited by 51
A Re-examination of the Relationship between Abuse Experience and Functional Bowel Disorders
Hobbis, I. C. A., Turpin, G., & Read, N. W. (2002) · Scandinavian Journal of Gastroenterology · doi:10.1080/003655202317316051 · Cited by 49
Diagnostic criteria in IBS: useful or not?
Mearin, F., & Lacy, B. (2012) · Neurogastroenterology and Motility · doi:10.1111/j.1365-2982.2012.01992.x · Cited by 47
Prevalence of Functional Gastrointestinal Disorders in Women Who Report Domestic Violence to the Police
Perona, M. C., Benasayag, R., Juan, A. P., Santos, J., Zárate-López, N., Zárate, P., & Mearin, F. (2005) · Clinical Gastroenterology and Hepatology · doi:10.1016/s1542-3565(04)00776-1 · Cited by 47
Report From the Multinational Irritable Bowel Syndrome Initiative 2012
Pimentel, M., Talley, N. J., Quigley, E. M. M., Hani, A. C., Sharara, A. I., & Mahachai, V. (2013) · Gastroenterology · doi:10.1053/j.gastro.2013.04.049 · Cited by 47
Genetics and Genotypes in Irritable Bowel Syndrome: Implications for Diagnosis and Treatment
Park, M. I., & Camilleri, M. (2005) · Gastroenterology Clinics of North America · doi:10.1016/j.gtc.2005.02.009 · Cited by 46
Epidemiology of FGID symptoms in Japanese general population with reference to life style
Hongo, M. (2011) · Journal of Gastroenterology and Hepatology · doi:10.1111/j.1440-1746.2011.06632.x · Cited by 44
Irritable bowel syndrome
Frigerio, G., Beretta, A., Orsenigo, G., Tadeo, G., Imperiali, G., & Minoli, G. (1992) · Digestive Diseases and Sciences · doi:10.1007/bf01308166 · Cited by 43
The Role of Fiber in the Treatment of Irritable Bowel Syndrome
Zuckerman, M. J. (2005) · Journal of Clinical Gastroenterology · doi:10.1097/01.mcg.0000196405.15110.bb · Cited by 42
An update on irritable bowel syndrome: from diagnosis to emerging therapies
CHANG, J. Y., & Talley, N. J. (2010) · Current Opinion in Gastroenterology · doi:10.1097/mog.0b013e3283414065 · Cited by 42
The genetics of irritable bowel syndrome.
Saito, Y., Petersen, G., Locke, G., & Talley, N. J. (2005) · Clinical Gastroenterology and Hepatology · doi:10.1016/s1542-3565(05)00184-9 · Cited by 42
Role of Radiologic Imaging in Irritable Bowel Syndrome: Evidence-based Review
O’Connor, O. J., McSweeney, S. E., McWilliams, S., O’Neill, S. B., Shanahan, F., Quigley, E. M. M., & Maher, M. M. (2011) · Radiology · doi:10.1148/radiol.11110423 · Cited by 42
Protease activated receptor 2: a new target for IBS treatment.
Bueno, L. P. (2008) · PubMed · Cited by 42
Irritable bowel syndrome: Physicians' awareness and patients' experience
Olafsdottir, L. B. (2012) · World Journal of Gastroenterology · doi:10.3748/wjg.v18.i28.3715 · Cited by 41
Elevated motility‐related transmucosal potential difference in the upper small intestine in the irritable bowel syndrome
Larsson, M., Simrén, M., Thomas, E. A., Bornstein, J. C., Lindström, E., & Sjövall, H. (2007) · Neurogastroenterology & Motility · doi:10.1111/j.1365-2982.2007.00941.x · Cited by 41
Mucosal Barrier Defects in Irritable Bowel Syndrome. Who Left the Door Open?
Barbara, G. (2006) · The American Journal of Gastroenterology · doi:10.1038/ajg2006242 · Cited by 41
Kruis scoring system and Manning's criteria in diagnosis of irritable bowel syndrome: is it better to use combined?
Doğan, U. B., & Ünal, S. (1997) · PubMed · Cited by 41
Utilization patterns and net direct medical cost to Medicaid of irritable bowel syndrome
Martin, B. C., Ganguly, R., Pannicker, S., Frech, F. H., & Barghout, V. E. (2003) · Current Medical Research and Opinion · doi:10.1185/030079903125002540 · Cited by 35
New Clinical Method for Distinguishing D-IBS from Other Gastrointestinal Conditions Causing Diarrhea: The LA/IBS Diagnostic Strategy
Pimentel, M., Hwang, L. J., MELMED, G. Y., Low, K., Vasiliauskas, E., Ippoliti, A., Yang, J. M., Lezcano, S., Conklin, J. L., & Sahakian, A. B. (2009) · Digestive Diseases and Sciences · doi:10.1007/s10620-008-0694-z · Cited by 32
Predictors of treatment outcome after cognitive behavior therapy and antispasmodic treatment for patients with irritable bowel syndrome in primary care
Reme, S. E., Kennedy, T., Jones, R., Darnley, S., & Chalder, T. (2010) · Journal of Psychosomatic Research · doi:10.1016/j.jpsychores.2010.01.003 · Cited by 31
Food intolerance and skin prick test in treated and untreated irritable bowel syndrome
Jun, D. W. (2006) · World Journal of Gastroenterology · doi:10.3748/wjg.v12.i15.2382 · Cited by 30
Therapeutic value of a gastroenterology consultation in irritable bowel syndrome
Ilnyckyj, A., Graff, L. A., Blanchard, J., & Bernstein, C. N. (2003) · Alimentary Pharmacology & Therapeutics · doi:10.1046/j.1365-2036.2003.01523.x · Cited by 30
Prevalence, comorbidity, and risk factors for functional bowel symptoms: a population-based survey in Northern Norway
Breckan, R. K., Asfeldt, A. M., Straume, B., Florholmen, J., & Paulssen, E. J. (2012) · Scandinavian Journal of Gastroenterology · doi:10.3109/00365521.2012.688215 · Cited by 30
Value of Different Diagnostic Criteria for the Irritable Bowel Syndrome Among Men and Women
Hammer, J., & Talley, N. J. (2008) · Journal of Clinical Gastroenterology · doi:10.1097/mcg.0b013e3181574d48 · Cited by 29
Correlation between symptoms of the irritable bowel syndrome and the response to the food extract skin prick test
Soares, R. L. S., de Figueiredo, H. N., MANESCHY, C. P., Rocha, V. R. S., & Santos, J. M. (2004) · Brazilian Journal of Medical and Biological Research · doi:10.1590/s0100-879x2004000500005 · Cited by 27
Self-citation
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A systematic review of tegaserod for the treatment of irritable bowel syndrome
Jones, B. W., Moore, D., Robinson, S., & Song, F. (2002) · Journal of Clinical Pharmacy and Therapeutics · doi:10.1046/j.1365-2710.2002.00426.x · Cited by 25
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Hershfield, N. (2005) · Canadian Journal of Gastroenterology · doi:10.1155/2005/978794 · Cited by 24
Bacitracin reveals a role for multiple thiol isomerases in platelet function
Robinson, A. A., O'Neill, S., Kiernan, A., O'Donoghue, N. M., & Moran, N. M. (2005) · British Journal of Haematology · doi:10.1111/j.1365-2141.2005.05878.x · Cited by 23
Irritable bowel syndrome: a multidimensional disorder cannot be understood or treated from a unidimensional perspective
Sperber, A. D., & Drossman, D. A. (2012) · Therapeutic Advances in Gastroenterology · doi:10.1177/1756283x12460420 · Cited by 22
Associations between medication use and functional gastrointestinal disorders: a population‐based study
Choung, R. S., Locke, G. R., Schleck, C. D., Zinsmeister, A. R., & Talley, N. J. (2013) · Neurogastroenterology & Motility · doi:10.1111/nmo.12082 · Cited by 21
Prevalence of irritable bowel syndrome in a Brazilian Amazon community
Soares, R. L. S., dos Santos, J. M., & Rocha, V. R. S. (2005) · Neurogastroenterology & Motility · doi:10.1111/j.1365-2982.2005.00722.x · Cited by 19
Self-citation
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Síndrome del intestino irritable y enfermedad inflamatoria intestinal: ¿alguna conexión?
Mearin, F., Juan, A. P., & Balboa, A. (2009) · Gastroenterología y Hepatología · doi:10.1016/j.gastrohep.2008.12.007 · Cited by 19
Discrepancies between the responses to skin prick test to food and respiratory antigens in two subtypes of patients with irritable bowel syndrome
Soares, R. L. S., de Figueiredo, H. N., Santos, J. M., Oliveira, R., Godoy, R. L., & Mendonça, F. A. (2008) · World Journal of Gastroenterology · doi:10.3748/wjg.14.3044 · Cited by 13
Self-citation
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Habba, S. F. (2000) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2000.02219.x · Cited by 12
Bronchial Hyperresponsiveness in Irritable Bowel Syndrome
Jun, D. W., Lee, O. Y., Yoon, H. J., Lee, H. L., Yoon, B. C., Choi, H. S., Lee, M. H., Lee, D. H., & Kee, C. S. (2005) · Digestive Diseases and Sciences · doi:10.1007/s10620-005-2916-y · Cited by 12
Importance of Early Diagnosis in Patients with Irritable Bowel Syndrome
Halpert, A. D. (2010) · Postgraduate Medicine · doi:10.3810/pgm.2010.03.2127 · Cited by 8
Statistical validation of endophenotypes using a surrogate endpoint analytic analogue
Huang, G., Hsieh, C., Chen, C., & Chen, W. J. (2009) · Genetic Epidemiology · doi:10.1002/gepi.20407 · Cited by 8
THE PREVALENCE AND CLINICAL CHARACTERISTICS OF PRIMARY HEADACHE IN IRRITABLE BOWEL SYNDROME: a subgroup of the functional somatic syndromes
Soares, R. L. S., Filho, P. F. M., MANESCHY, C. P., BREIJÃO, J. F., & SCHMIDTE, N. M. (2013) · Arquivos de Gastroenterologia · doi:10.1590/s0004-28032013000400008 · Cited by 6
Self-citation
Ismar Boas: Father of Gastroenterology and Founder of the Oldest Surviving Publication in Digestive Diseases
Brandt, L. J. (2011) · The American Journal of Gastroenterology · doi:10.1038/ajg.2010.386 · Cited by 6
Irritable Bowel Syndrome
Saito, Y. A., Talley, N. J., & Locke, G. R. (2007) · Wiley eBooks · doi:10.1002/9780470692189.ch24 · Cited by 4
The prevalence and clinical characteristics of atopic manifestations in patients with irritable bowel syndrome in a Brazilian urban community
Soares, R. L. S., de Figueiredo, H. N., Filho, P. F. M., Oliveira, R., Gonçalves, C. D., Micuci, A. J. Q. R., Parada, B. A., Brandão, I. B., & Rodrigues, C. C. (2010) · Gastroenterology Insights · doi:10.4081/gi.2010.e11 · Cited by 3
Self-citation

Research works printed but not linked: 4

Cumming W. Electrogalvinism in a particular affliction of mucous membrane of the bowels. London Med Gaz 1948;59:969-973.
10.1111/j.1365-2982.2008.0114x · DOI
10.5056/jnm.2011.17.2.13 · DOI
10.1111/j.1365-2036.2009.04081 · DOI

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Authors: Soares, R. L.
Venue: World Journal of Gastroenterology
Publisher: Baishideng Publishing Group Inc.
Published: 2014
Volume: 20
Issue: 34
Pages: 12144
ISSN: 1007-9327 (ISSN-L)
DOI: 10.3748/wjg.v20.i34.12144
PMC: PMC4161800
OpenAlex: W2040223383
Cited by: 266
References: 271
Citations by year: 2026: 12 · 2025: 15 · 2024: 16 · 2023: 38 · 2022: 26 · 2021: 28 · 2020: 24 · 2019: 23 · 2018: 21 · 2017: 22 · 2016: 24 · 2015: 16 · 2014: 1
FWCI: 3.49
Type: journal article
Language: en
Open access: hybrid
doi.org
Licence: cc-by-nc
Locations: World Journal of Gastroenterology (publishedVersion, cc-by-nc)
Europe PMC (PubMed Central) (publishedVersion)
PubMed Central (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Gastroenterology › Gastrointestinal motility and disorders
Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Infant Health and Development
Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gut microbiota and health
Keywords: irritable bowel syndrome, Rome criteria, biopsychosocial model, IBS pathophysiology, IBS diagnosis, non-pharmacological treatment, pharmacotherapy, physician-patient relationship, quality of life, prevalence
MeSH terms: Combined Modality Therapy, Humans, Predictive Value of Tests, Risk Factors, Prevalence, Treatment Outcome, Irritable Bowel Syndrome

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