Cited by 266Gastrointestinal motility and disordersInfant Health and DevelopmentGut microbiota and health

The DOI matches its Crossref record; 271 of the 271 references it cites were found in a registry or an index.

Irritable bowel syndrome: A clinical review

Open access

Soares, Rosa LS·2014·World Journal of Gastroenterology

DOI 10.3748/wjg.v20.i34.12144PMC PMC4161800

Open this paper in CoChat — free account Open PDF

Abstract

Irritable bowel syndrome (IBS) remains a clinical challenge in the 21(st) century. It's the most commonly diagnosed gastrointestinal condition and also the most common reason for referral to gastroenterology clinics. Its can affect up to one in five people at some point in their lives, and has a significantly impact of life quality and health care utilization. The prevalence varies according to country and criteria used to define IBS. Various mechanisms and theories have been proposed about its etiology, but the biopsychosocial model is the most currently accepted for IBS. The complex of symptoms would be the result of the interaction between psychological, behavioral, psychosocial and environmental factors. The diagnosis of IBS is not confirmed by a specific test or structural abnormality. It is made using criteria based on clinical symptoms such as Rome criteria, unless the symptoms are thought to be atypical. Today the Rome Criteria III is the current gold-standard for the diagnoses of IBS. Secure positive evidence of IBS by means of specific disease marker is currently not possible and cannot be currently recommended for routine diagnosis. There is still no clinical evidence to recommend the use of biomarkers in blood to diagnose IBS. However, a number of different changes in IBS patients were demonstrated in recent years, some of which can be used in the future as a diagnostic support. IBS has no definitive treatment but could be controlled by non-pharmacologic management eliminating of some exacerbating factors such certain drugs, stressor conditions and changes in dietary habits.The traditional pharmacologic management of IBS has been symptom based and several drugs have been used. However, the cornerstone of its therapy is a solid patient physician relationship. This review will provide a summary of pathophysiology, diagnostic criteria and current and emerging therapies for IBS.

Integrity signals

Registry

Crossref · 10.3748/wjg.v20.i34.12144

Cites

271 of 271 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

We couldn’t retrieve this paper’s full text, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

The Endophenotype Concept in Psychiatry: Etymology and Strategic Intentions
Gottesman, I. I., & Gould, T. D. (2003) · American Journal of Psychiatry · doi:10.1176/appi.ajp.160.4.636 · Cited by 5,615
Functional Bowel Disorders
Longstreth, G. F., Thompson, W. G., Chey, W. D., Houghton, L. A., Mearin, F., & Spiller, R. C. (2006) · Gastroenterology · doi:10.1053/j.gastro.2005.11.061 · Cited by 4,856
The functional gastrointestinal disorders and the Rome III process
Drossman, D. A. (2006) · Gastroenterology · doi:10.1053/j.gastro.2006.03.008 · Cited by 2,416
U. S. Householder survey of functional gastrointestinal disorders: Prevalence, sociodemography, and health impact
Drossman, D. A., Li, Z., Andruzzi, E., Temple, R. D., Talley, N. J., Grant Thompson, W., Whitehead, W. E., Janssens, J., Funch-Jensen, P., Corazziari, E., et al. (1993) · Digestive Diseases and Sciences · doi:10.1007/bf01303162 · Cited by 2,198
Global Prevalence of and Risk Factors for Irritable Bowel Syndrome: A Meta-analysis
Lovell, R. M., & Ford, A. C. (2012) · Clinical Gastroenterology and Hepatology · doi:10.1016/j.cgh.2012.02.029 · Cited by 2,155
Gut feelings: the emerging biology of gut-brain communication
Mayer, E. A. (2011) · Nature Reviews Neuroscience · doi:10.1038/nrn3071 · Cited by 1,726
Activated mast cells in proximity to colonic nerves correlate with abdominal pain in irritable bowel syndrome
Barbara, G., Stanghellini, V., De Giorgio, R., Cremon, C., Cottrell, G. S., Santini, D., Pasquinelli, G., Morselli-Labate, A. M., Grady, E. F., Bunnett, N. W., et al. (2004) · Gastroenterology · doi:10.1053/j.gastro.2003.11.055 · Cited by 1,475
Towards positive diagnosis of the irritable bowel.
Manning, A. P., Thompson, W., Heaton, K. W., & Morris, A. F. (1978) · BMJ · doi:10.1136/bmj.2.6138.653 · Cited by 1,404
AGA technical review on irritable bowel syndrome.
Drossman, D. A., Camilleri, M., Mayer, E. A., & Whitehead, W. E. (2002) · Gastroenterology · doi:10.1053/gast.2002.37095 · Cited by 1,384
Components of placebo effect: randomised controlled trial in patients with irritable bowel syndrome
Kaptchuk, T. J., Kelley, J. M., Conboy, L. A., Davis, R. B., Kerr, C. E., Jacobson, E. E., Kirsch, I., Schyner, R. N., Nam, B. H., Nguyen, L. T., et al. (2008) · BMJ · doi:10.1136/bmj.39524.439618.25 · Cited by 1,196

Show all 271 references

Research works printed but not linked: 4

Cumming W. Electrogalvinism in a particular affliction of mucous membrane of the bowels. London Med Gaz 1948;59:969-973.
10.1111/j.1365-2982.2008.0114x · DOI
10.5056/jnm.2011.17.2.13 · DOI
10.1111/j.1365-2036.2009.04081 · DOI

Sorted by citations

Impact of the Gut Microbiota on Intestinal Immunity Mediated by Tryptophan Metabolism
Gao, J., Xu, K., Liu, H., Liu, G., Bai, M., Peng, C., Li, T., & Yin, Y. (2018) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2018.00013 · Cited by 1,357
Breaking down the barriers: the gut microbiome, intestinal permeability and stress-related psychiatric disorders
Kelly, J. R., Kennedy, P. J., Cryan, J. F., Dinan, T. G., Clarke, G., & Hyland, N. P. (2015) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2015.00392 · Cited by 1,110
Faecal microbiota transplantation alters gut microbiota in patients with irritable bowel syndrome: results from a randomised, double-blind placebo-controlled study
Halkjær, S. I., Christensen, A. H., Lo, B. Z. S., Browne, P. D., Günther, S., Hansen, L. H., & Petersen, A. M. (2018) · Gut · doi:10.1136/gutjnl-2018-316434 · Cited by 357
The Microbiome and Irritable Bowel Syndrome – A Review on the Pathophysiology, Current Research and Future Therapy
Chong, P. P., Chin, V. K., Looi, C. Y., Wong, W. F., Madhavan, P., & Yong, P. V. C. (2019) · Frontiers in Microbiology · doi:10.3389/fmicb.2019.01136 · Cited by 353
Confocal Endomicroscopy Shows Food-Associated Changes in the Intestinal Mucosa of Patients With Irritable Bowel Syndrome
Fritscher-Ravens, A., Schuppan, D., Ellrichmann, M., Schoch, S., Röcken, C., Brasch, J., Bethge, J., Böttner, M., Klose, J., & Milla, P. J. (2014) · Gastroenterology · doi:10.1053/j.gastro.2014.07.046 · Cited by 329
Many Patients With Irritable Bowel Syndrome Have Atypical Food Allergies Not Associated With Immunoglobulin E
Fritscher-Ravens, A., Pflaum, T., Mösinger, M., Ruchay, Z., Röcken, C., Milla, P. J., Das, M., Böttner, M., Wedel, T., & Schuppan, D. (2019) · Gastroenterology · doi:10.1053/j.gastro.2019.03.046 · Cited by 248
Effects of varying dietary content of fermentable short‐chain carbohydrates on symptoms, fecal microenvironment, and cytokine profiles in patients with irritable bowel syndrome
Hustoft, T. N., Hausken, T., Ystad, S. O., Valeur, J., Brokstad, K. A., Hatlebakk, J. G., & Lied, G. A. (2016) · Neurogastroenterology & Motility · doi:10.1111/nmo.12969 · Cited by 220
Differences in Fecal Microbiomes and Metabolomes of People With vs Without Irritable Bowel Syndrome and Bile Acid Malabsorption
Jeffery, I. B., Das, A., O’Herlihy, E. A., Coughlan, S., Cisek, K. K., Moore, M., Bradley, F., Carty, T., Pradhan, M., Dwibedi, C. K., et al. (2019) · Gastroenterology · doi:10.1053/j.gastro.2019.11.301 · Cited by 208
A Clostridia-rich microbiota enhances bile acid excretion in diarrhea-predominant irritable bowel syndrome
Zhao, L., Yang, W., Chen, Y., Huang, F., Lu, L., Lin, C., Huang, T., Ning, Z., Zhai, L., Zhong, L. L. D., et al. (2019) · Journal of Clinical Investigation · doi:10.1172/jci130976 · Cited by 202
Diet therapy for inflammatory bowel diseases: The established and the new
Durchschein, F., Petritsch, W., & Hammer, H. F. (2016) · World Journal of Gastroenterology · doi:10.3748/wjg.v22.i7.2179 · Cited by 147
Efficacy of a low-FODMAP diet in adult irritable bowel syndrome: a systematic review and meta-analysis
van Lanen, A., de Bree, A., & Greyling, A. (2021) · European Journal of Nutrition · doi:10.1007/s00394-020-02473-0 · Cited by 151
Recent developments in the pathophysiology of irritable bowel syndrome
El-Salhy, M. (2015) · World Journal of Gastroenterology · doi:10.3748/wjg.v21.i25.7621 · Cited by 111
Probiotic Saccharomyces cerevisiae strains as biotherapeutic tools: is there room for improvement?
Palma, M. L., Zamith‐Miranda, D., Martins, F. S., Bozza, F. A., Nimrichter, L., Montero-Lomelı́, M., Marques, E. T. A., & Douradinha, B. G. (2015) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-015-6776-x · Cited by 111
Patients with irritable bowel syndrome-diarrhea have lower disease-specific quality of life than irritable bowel syndrome-constipation
Singh, P. (2015) · World Journal of Gastroenterology · doi:10.3748/wjg.v21.i26.8103 · Cited by 111
Diet in irritable bowel syndrome
El‐Salhy, M., & Gundersen, D. (2015) · Nutrition Journal · doi:10.1186/s12937-015-0022-3 · Cited by 115
New insights into the pathogenesis and treatment of irritable bowel syndrome
Oświęcimska, J. M., Szymlak, A., Roczniak, W., Girczys-Połedniok, K., & Kwiecień, J. (2017) · Advances in Medical Sciences · doi:10.1016/j.advms.2016.11.001 · Cited by 113
Low fermentable oligosaccharides, disaccharides, monosaccharides, and polyols diet compared with traditional dietary advice for diarrhea-predominant irritable bowel syndrome: a parallel-group, randomized controlled trial with analysis of clinical and microbiological factors associated with patient outcomes
Zhang, Y., Feng, L., Wang, X., Fox, M. R., Luo, L., Du, L., Chen, B., Chen, X., He, H., Zhu, S., et al. (2021) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/nqab005 · Cited by 102
Economic burden of irritable bowel syndrome in China
Zhang, F., Xiang, W., Li, C.-Y., & Li, S.-C. (2016) · World Journal of Gastroenterology · doi:10.3748/wjg.v22.i47.10450 · Cited by 94
Uncovering the pathophysiology of irritable bowel syndrome by exploring the gut-brain axis: a narrative review
Tang, H.-Y., Jiang, A., Wang, X., Wang, H., Guan, Y., Li, F., & Shen, G.-M. (2021) · Annals of Translational Medicine · doi:10.21037/atm-21-2779 · Cited by 87
The Role of Mast Cells in Irritable Bowel Syndrome
Lee, K. N., & Lee, O. Y. (2016) · Gastroenterology Research and Practice · doi:10.1155/2016/2031480 · Cited by 90
Cellular and molecular effects of yeast probiotics on cancer
Saber, A., Alipour, B., Faghfoori, Z., & Khosroushahi, A. Y. (2016) · Critical Reviews in Microbiology · doi:10.1080/1040841x.2016.1179622 · Cited by 83
Constipation-Predominant Irritable Bowel Syndrome (IBS-C): Effects of Different Nutritional Patterns on Intestinal Dysbiosis and Symptoms
Rosa, C. D., Altomare, A., Terrigno, V., Carbone, F., Tack, J. F., Cicala, M., & Guarino, M. P. L. (2023) · Nutrients · doi:10.3390/nu15071647 · Cited by 87
Limited prolonged effects of rifaximin treatment on irritable bowel syndrome-related differences in the fecal microbiome and metabolome
Żeber‐Lubecka, N., Kulecka, M., Ambrożkiewicz, F., Paziewska, A., Goryca, K., Karczmarski, J., Rubel, T., Wojtowicz, W., Młynarz, P., Marczak, Ł., et al. (2016) · Gut Microbes · doi:10.1080/19490976.2016.1215805 · Cited by 77
Effect of the probiotic strain Bifidobacterium animalis subsp. lactis , BB-12 ® , on defecation frequency in healthy subjects with low defecation frequency and abdominal discomfort: a randomised, double-blind, placebo-controlled, parallel-group trial
Eskesen, D., Jespersen, L., Michelsen, B., Whorwell, P. J., Müller-Lissner, S., & Morberg, C. M. (2015) · British Journal of Nutrition · doi:10.1017/s0007114515003347 · Cited by 78
Gut Microbiota‐Bile Acid Crosstalk in Diarrhea‐Irritable Bowel Syndrome
Zhan, K., Zheng, H., Jian-qing, L., Wu, H., Qin, S., Luo, L., & Huang, S. (2020) · BioMed Research International · doi:10.1155/2020/3828249 · Cited by 72
Irritable bowel syndrome - from etiopathogenesis to therapy
Radovanović-Dinić, B., Tešić-Rajković, S., Grgov, S., Petrović, G., & Zivkovic, V. G. (2018) · Biomedical Papers · doi:10.5507/bp.2017.057 · Cited by 75
Novel treatment strategies for smooth muscle disorders: Targeting Kv7 potassium channels
Haick, J. M., & Byron, K. L. (2016) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2016.05.002 · Cited by 62
Cell Type-Specific Extracellular Vesicles and Their Impact on Health and Disease
Amin, S., Massoumi, H., Tewari, D., Roy, A. K., Chaudhuri, M., Jazayerli, C., Krishan, A., Singh, M., Soleimani, M., Karaca, E. E., et al. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25052730 · Cited by 66
Depressive symptoms in patients with irritable bowel syndrome: a meta-analysis of comparative studies
Zhang, Q., Wang, F., Geng, Q., Zheng, W., Ng, C. H., Ungvari, G. S., Yuan, Z., Mei, S., Wang, G., & Xiang, Y. (2018) · International Journal of Biological Sciences · doi:10.7150/ijbs.25001 · Cited by 64
Neuromodulation and the Gut–Brain Axis: Therapeutic Mechanisms and Implications for Gastrointestinal and Neurological Disorders
Aljeradat, B., Kumar, D., Abdulmuizz, S., Kundu, M., Almealawy, Y. F., Batarseh, D. R., Atallah, O., Ennabe, M., Alsarafandi, M., Alan, A., et al. (2024) · Pathophysiology · doi:10.3390/pathophysiology31020019 · Cited by 71
Saccharomyces cerevisiaeCNCM I-3856 in irritable bowel syndrome: An individual subject meta-analysis
Decherf, A. C., Pélerin, F., Leuillet, S., Douillard, B., Housez, B., Cazaubiel, M., Jacobson, G. K., Jüsten, P., & Desreumaux, P. (2017) · World Journal of Gastroenterology · doi:10.3748/wjg.v23.i2.336 · Cited by 67
Non-celiac gluten sensitivity: All wheat attack is not celiac
Igbinedion, S. O., Ansari, J., Vasikaran, A., Gavins, F. N. E., Jordan, P., Boktor, M., & Alexander, J. S. (2017) · World Journal of Gastroenterology · doi:10.3748/wjg.v23.i40.7201 · Cited by 58
Corticotropin-releasing factor receptor type 1 and type 2 interaction in irritable bowel syndrome
Nozu, T., & Okumura, T. (2015) · Journal of Gastroenterology · doi:10.1007/s00535-015-1086-8 · Cited by 59
Epidemiology of irritable bowel syndrome and its associated factors in Saudi undergraduate students
AlButaysh, O. F., ALQuraini, A. A., Almukhaitah, A. A., Alahmdi, Y. M., & Alharbi, F. (2020) · Saudi Journal of Gastroenterology · doi:10.4103/sjg.sjg_459_19 · Cited by 63
Visceral hypersensitive rats share common dysbiosis features with irritable bowel syndrome patients
Zhou, X.-Y. (2016) · World Journal of Gastroenterology · doi:10.3748/wjg.v22.i22.5211 · Cited by 49
Aloe vera Is Effective and Safe in Short-term Treatment of Irritable Bowel Syndrome: A Systematic Review and Meta-analysis
Hong, S. W., Chun, J., Park, S., Lee, H. J., Im, J. P., & Kim, J. S. (2018) · Journal of Neurogastroenterology and Motility · doi:10.5056/jnm18077 · Cited by 45
Peppermint a medicinal herb and treasure of health: A review
Nayak, P., Kumar, T., Gupta, A., & Joshi, N. (2020) · Journal of Pharmacognosy and Phytochemistry · doi:10.22271/phyto.2020.v9.i3y.11525 · Cited by 45
Tomato-fruit-derived extracellular vesicles inhibit Fusobacterium nucleatum via lipid-mediated mechanism
Lee, B., Wu, S., Chien, H.-Y., Shen, T., & Hsu, W.-H. (2023) · Food & Function · doi:10.1039/d3fo01608k · Cited by 43
Structure-Based Discovery of Novel and Selective 5-Hydroxytryptamine 2B Receptor Antagonists for the Treatment of Irritable Bowel Syndrome
Zhou, Y., Ma, J., Lin, X., Huang, X., Wu, K., & Huang, N. (2015) · Journal of Medicinal Chemistry · doi:10.1021/acs.jmedchem.5b01631 · Cited by 42
Irritable bowel syndrome among nurses working in King Abdulaziz University Hospital, Jeddah, Saudi Arabia
Ibrahim, N. K., Al-Bloushy, R. I., Sait, S., Al-Azhary, H. W., Bar, N. H. A., & Mirdad, G. A. (2016) · Libyan Journal of Medicine · doi:10.3402/ljm.v11.30866 · Cited by 44
Noninvasive Diagnosis of Irritable Bowel Syndrome via Bowel Sound Features: Proof of Concept
Du, X., Allwood, G., Webberley, K. M., Inderjeeth, A., Osseiran, A., & Marshall, B. J. (2019) · Clinical and Translational Gastroenterology · doi:10.14309/ctg.0000000000000017 · Cited by 45
Sexual Dysfunction in Patients With Chronic Gastrointestinal and Liver Diseases: A neglected Issue
Romano, L., Granata, L., Fusco, F., Napolitano, L., Cerbone, R., Priadko, K., Sciorio, C., Mirone, V., & Romano, M. (2021) · Sexual Medicine Reviews · doi:10.1016/j.sxmr.2021.02.002 · Cited by 41
Anti-inflammatory and tight junction protective activity of the herbal preparation STW 5-II on mouse intestinal organoids
Elbadawi, M., Ammar, R. M., Aziz-Kalbhenn, H., Rabini, S., Klauck, S. M., Dawood, M., Saeed, M. E. M., Kampf, C. J., & Efferth, T. (2021) · Phytomedicine · doi:10.1016/j.phymed.2021.153589 · Cited by 39
Long-Term Follow-Up Results of Fecal Microbiota Transplantation for Irritable Bowel Syndrome: A Single-Center, Retrospective Study
Cui, J., Lin, Z., Tian, H., Yang, B. K., Zhao, D., Ye, C., Li, N., Qin, H., & Chen, Q. (2021) · Frontiers in Medicine · doi:10.3389/fmed.2021.710452 · Cited by 40
A New Generation of Probiotic Functional Beverages Using Bioactive Compounds From Agro-Industrial Waste
Vodnar, D. C., Călinoiu, L. F., Mitrea, L., Precup, G., Bindea, M., Păcurar, A. M., Szabo, K., & Ștefănescu, B. E. (2019) · Elsevier eBooks · doi:10.1016/b978-0-12-816397-9.00015-7 · Cited by 37
Does symptom activity explain psychological differences in patients with irritable bowel syndrome and inflammatory bowel disease? Results from a multi-center cross-sectional study
Berens, S., Schaefert, R., Baumeister, D., Gauss, A., Eich, W., & Tesarz, J. (2019) · Journal of Psychosomatic Research · doi:10.1016/j.jpsychores.2019.109836 · Cited by 37
Psychotherapeutic Interventions in Irritable Bowel Syndrome
Hetterich, L., & Stengel, A. (2020) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2020.00286 · Cited by 46
The Route to Palatable Fecal Microbiota Transplantation
Fadda, H. M. (2020) · AAPS PharmSciTech · doi:10.1208/s12249-020-1637-z · Cited by 36
Use of Complementary and Alternative Medicine by Patients with Irritable Bowel Syndrome According to the Roma IV Criteria: A Single-Center Italian Survey
Larussa, T., Rossi, M., Suraci, E., Marasco, R., Imeneo, M., Abenavoli, L., & Luzza, F. (2019) · Medicina · doi:10.3390/medicina55020046 · Cited by 30
Relationship between adverse childhood experiences and illness anxiety in irritable bowel syndrome – The impact of gender
Berens, S., Banzhaf, P., Baumeister, D., Gauss, A., Eich, W., Schaefert, R., & Tesarz, J. (2019) · Journal of Psychosomatic Research · doi:10.1016/j.jpsychores.2019.109846 · Cited by 29
The combination of oligo- and polysaccharides and reticulated protein for the control of symptoms in patients with irritable bowel syndrome: Results of a randomised, placebo-controlled, double-blind, parallel group, multicentre clinical trial
Alexea, O., Bacârea, V., & Piqué, N. (2015) · United European Gastroenterology Journal · doi:10.1177/2050640615615050 · Cited by 28
The prevalence of irritable bowel syndrome among Saudi population in Riyadh by use of Rome IV criteria and self-reported dietary restriction
Amin, H. S., Irfan, F., Karim, S. I., Almeshari, S., Aldosari, K. A., Alzahrani, A. M., Almogbel, A. T., Alfouzan, S. M., & Alsaif, A. A. (2021) · Saudi Journal of Gastroenterology · doi:10.4103/sjg.sjg_43_21 · Cited by 28
The Prevalence and Risk Factors of Irritable Bowel Syndrome in Saudi Arabia in 2019
Alqahtani, N. H., & Mahfouz, M. E. M. (2022) · International Journal of Preventive Medicine · doi:10.4103/ijpvm.ijpvm_486_20 · Cited by 28
Efficacy of Chinese Herbal Medicine for Diarrhea‐Predominant Irritable Bowel Syndrome: A Meta‐Analysis of Randomized, Double‐Blind, Placebo‐Controlled Trials
Zhu, J., Liu, S., Xiaolan, S., Wang, Z.-S., Guo, Y., Li, Y., Yang, Y., Hou, L.-W., Wang, Q., Wei, R., et al. (2016) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2016/4071260 · Cited by 28
Association between Dietary Habits and Fecal Microbiota Composition in Irritable Bowel Syndrome Patients: A Pilot Study
Altomare, A., CHIERICO, F. D., Rocchi, G., Emerenziani, S., Nuglio, C., Putignani, L., Angeletti, S., Presti, A. L., Ciccozzi, M., Russo, A., et al. (2021) · Nutrients · doi:10.3390/nu13051479 · Cited by 28
Diagnosis and treatment of irritable bowel syndrome with predominant constipation in the primary-care setting: focus on linaclotide
Chandar, A. K. (2017) · International Journal of General Medicine · doi:10.2147/ijgm.s126581 · Cited by 28
Igg Food Antibody Guided Elimination-Rotation Diet Was More Effective than FODMAP Diet and Control Diet in the Treatment of Women with Mixed IBS—Results from an Open Label Study
Ostrowska, L., Wasiluk, D., Lieners, C., Gałęcka, M., Bartnicka, A., & Tveiten, D. (2021) · Journal of Clinical Medicine · doi:10.3390/jcm10194317 · Cited by 27
Probiotics, Prebiotics, Fecal Microbiota Transplantation, and Dietary Patterns in Inflammatory Bowel Disease
Noguera‐Fernández, N., Candela‐González, J., & Orenes‐Piñero, E. (2024) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.202400429 · Cited by 24
Consenso mexicano sobre el síndrome de intestino irritable
Carmona-Sánchez, R., Icaza-Chávez, M. E., Bielsa-Fernández, M. V., Gomez-Escudero, O., Bosques‐Padilla, F., Coss‐Adame, E., Esquivel-Ayanegui, F., Flores-Rendón, Á. R., González-Martínez, M. A., Huerta-Iga, F. M., et al. (2016) · Revista de Gastroenterología de México · doi:10.1016/j.rgmx.2016.01.004 · Cited by 26
Prevalence and impact of irritable bowel syndrome in people with epilepsy
Camara-Lemarroy, C. R., Escobedo-Zúñiga, N., Zacarias, D. O., Peña-Avendaño, J. J., Villarreal-Garza, E., & Díaz-Torres, M. A. (2016) · Epilepsy & Behavior · doi:10.1016/j.yebeh.2016.05.041 · Cited by 24
IRRITABLE BOWEL SYNDROME, FOOD INTOLERANCE AND NON- CELIAC GLUTEN SENSITIVITY. A NEW CLINICAL CHALLENGE
Soares, R. L. S. (2018) · Arquivos de Gastroenterologia · doi:10.1590/s0004-2803.201800000-88 · Cited by 25
Self-citation
Positive and negative acute phase reactants in sickle cell diseases
Helvacı, M. R., Altıntaşž, E., Yalçın, A., Muftuoglu, O. E., Abyad, A., & Pocock, L. (2022) · World Family Medicine Journal/Middle East Journal of Family Medicine · doi:10.5742/mewfm.2022.952509 · Cited by 21
Conceptualizing a subtype of patients with chronic pain
Spiegel, D. R., Shaukat, A. M., Mccroskey, A. L., Chatterjee, A. S., Ahmadi, T., Simmelink, D., Oldfield, E. C., Pryor, C. R., Faschan, M., & Raulli, O. (2015) · The International Journal of Psychiatry in Medicine · doi:10.1177/0091217415621268 · Cited by 23
A survey of gastroenterologists in the United States on the use of central neuromodulators for treating irritable bowel syndrome
Nulsen, B., LeBrett, W. G., Drossman, D. A., & Chang, L. (2021) · Alimentary Pharmacology & Therapeutics · doi:10.1111/apt.16467 · Cited by 21
Association between irritable bowel syndrome and asthma: a meta-analysis and systematic review
Deshmukh, F. (2019) · Annals of Gastroenterology · doi:10.20524/aog.2019.0426 · Cited by 19
Low fermentable oligosaccharides, disaccharides, monosaccharides, and polypols diet and irritable bowel syndrome in Asia
Zhang, Y., Feei, Z., Zhang, H., Pan, B., Li, Y., Majid, H. A., & Lee, Y. Y. (2018) · JGH Open · doi:10.1002/jgh3.12125 · Cited by 18
The Mexican consensus on irritable bowel syndrome
Carmona-Sánchez, R., Icaza-Chávez, M. E., Bielsa-Fernández, M. V., Gomez-Escudero, O., Bosques‐Padilla, F., Coss‐Adame, E., Esquivel-Ayanegui, F., Flores-Rendón, Á. R., González-Martínez, M. A., Huerta-Iga, F. M., et al. (2016) · Revista de Gastroenterología de México (English Edition) · doi:10.1016/j.rgmxen.2016.01.004 · Cited by 19
Association of irritable bowel syndrome and sleep apnea in patients referred to sleep laboratory
Ghiasi, F., Amra, B., Sebghatollahi, V., & Zavareh, F. A. (2017) · Journal of Research in Medical Sciences · doi:10.4103/jrms.jrms_523_16 · Cited by 19
Irritable Bowel Syndrome and Risk of Parkinson’s Disease in Finland: A Nationwide Registry-Based Cohort Study
Mertsalmi, T. H., But, A., Pekkonen, E., & Scheperjans, F. (2021) · Journal of Parkinson s Disease · doi:10.3233/jpd-202330 · Cited by 18
Impact of serum-derived bovine immunoglobulin/protein isolate therapy on irritable bowel syndrome and inflammatory bowel disease: a survey of patient perspective
Shaw, A. L., Tomanelli, A., Bradshaw, T., Petschow, B. W., & Burnett, B. P. (2017) · Patient Preference and Adherence · doi:10.2147/ppa.s134792 · Cited by 17
Impact of patient and disease characteristics on the efficacy and safety of eluxadoline for IBS-D: a subgroup analysis of phase III trials
Lacy, B. E., Harris, L. A., Chang, L., Lucak, S. L., Gutman, C. R., Dove, L. S., Covington, P. S., & Lembo, A. J. (2019) · Therapeutic Advances in Gastroenterology · doi:10.1177/1756284819841290 · Cited by 17
Clinical potential of eluxadoline in the treatment of diarrhea-predominant irritable bowel syndrome
Sobolewska-Włodarczyk, A., Włodarczyk, M., Storr, M., & Fichna, J. (2016) · Therapeutics and Clinical Risk Management · doi:10.2147/tcrm.s83722 · Cited by 18
Eluxadoline in the treatment of diarrhea-predominant irritable bowel syndrome
Özdener-Poyraz, A. E., & Rivkin, A. M. (2017) · Drug Design Development and Therapy · doi:10.2147/dddt.s127405 · Cited by 17
The role of AST-120 and protein-bound uremic toxins in irritable bowel syndrome: a therapeutic perspective
Mosińska, P., Storr, M., & Fichna, J. (2015) · Therapeutic Advances in Gastroenterology · doi:10.1177/1756283x15587866 · Cited by 16
Altered Brain Structure in Chronic Visceral Pain: Specific Differences in Gray Matter Volume and Associations With Visceral Symptoms and Chronic Stress
Öhlmann, H., Koenen, L. R., Labrenz, F., Engler, H., Theysohn, N., Langhorst, J., & Elsenbruch, S. (2021) · Frontiers in Neurology · doi:10.3389/fneur.2021.733035 · Cited by 17
The Effects of Agave Fructans in a Functional Food Consumed by Patients with Irritable Bowel Syndrome with Constipation: A Randomized, Double-Blind, Placebo-Controlled Trial
Camacho‐Díaz, B. H., Arenas-Ocampo, M. L., Osorio‐Díaz, P., Jiménez–Aparicio, A. R., Alvarado-Jasso, G. M., Saavedra-Briones, E., Valdovinos-Díaz, M. A., & Gómez-Reyes, E. (2023) · Nutrients · doi:10.3390/nu15163526 · Cited by 15
Optimal management of constipation associated with irritable bowel syndrome
Furnari, M., de Bortoli, N., Martinucci, I., Bodini, G., Marabotto, E., Moscatelli, A., Nero, L. D., Revelli, M., Savarino, E. V., Giannini, E. G., et al. (2015) · Therapeutics and Clinical Risk Management · doi:10.2147/tcrm.s54298 · Cited by 15
Association of anxiety‐depressive disorders with irritable bowel syndrome among patients attending a rural family practice center: a comparative cross‐sectional study
Mohammed, A. A., Moustafa, H. A., Nour-Eldein, H., & Saudi, R. A. (2021) · General Psychiatry · doi:10.1136/gpsych-2021-100553 · Cited by 17
Possible role of intestinal stem cells in the pathophysiology of irritable bowel syndrome
El‐Salhy, M. (2020) · World Journal of Gastroenterology · doi:10.3748/wjg.v26.i13.1427 · Cited by 15
Menthacarin induces calcium ion influx in sensory neurons, macrophages and colonic organoids of mice
Zhang, Z., Engel, M. A., Koch, E., Reeh, P. W., & Khalil, M. (2020) · Life Sciences · doi:10.1016/j.lfs.2020.118682 · Cited by 14
Is the Gut Microbiota a Neglected Aspect of Gut and Brain Disorders?
Balan, Y., Archana Gaur, T., Sakthivadivel, V., Kamble, B. D., & Sundaramurthy, R. (2021) · Cureus · doi:10.7759/cureus.19740 · Cited by 14
Evaluation of the effects of the FODMAP diet and probiotics on irritable bowel syndrome (IBS) symptoms, quality of life and depression in women with IBS
Ustaoğlu, T., Tek, N. A., & Yıldırım, A. E. (2023) · Journal of Human Nutrition and Dietetics · doi:10.1111/jhn.13194 · Cited by 13
Association Between Irritable Bowel Syndrome and Sleep Disturbance in Adolescents
Noor, L. I. K., Bakri, A., Soejadhi, R., & Kesuma, Y. (2020) · Adolescent Health Medicine and Therapeutics · doi:10.2147/ahmt.s248711 · Cited by 14
An evaluation of dietary adequacy among patients with constipation-predominant irritable bowel syndrome in Malaysia
Shafiee, N. H., Razalli, N. H., Mokhtar, N. M., Tan, E., & Ali, R. A. R. (2021) · Intestinal Research · doi:10.5217/ir.2020.00050 · Cited by 13
Symptom Severity Following Rifaximin and the Probiotic VSL#3 in Patients with Chronic Pelvic Pain Syndrome (Due to Inflammatory Prostatitis) Plus Irritable Bowel Syndrome
Vicari, E. S. D., Salemi, M., Sidoti, G., Malaguarnera, M., & Castiglione, R. (2017) · Nutrients · doi:10.3390/nu9111208 · Cited by 13
Heat shock protein 70 protects mouse against post-infection irritable bowel syndrome via up-regulating intestinal γδ T cell’s Th17 response
He, Z., Sun, X., Ma, Z., Fu, J., Huang, B.-L., Liu, F., Chen, Y., Deng, T., Han, X., Sun, D., et al. (2018) · Cell & Bioscience · doi:10.1186/s13578-018-0237-z · Cited by 13
The impact of gastrointestinal conditions on psychosocial factors associated with the biopsychosocial model of health: A scoping review
Dent, E., Davinson, N., & Wilkie, S. (2021) · Applied Psychology Health and Well-Being · doi:10.1111/aphw.12323 · Cited by 13
Irritable Bowel Syndrome: Prevalence and Determinants Among Adults in the Makkah Region, Saudi Arabia
Hafiz, T. A., Alhemayed, T. S., Mandorah, R. H., Alshanqiti, A. A., Almohaimeed, R. A., & Noor, O. M. (2023) · Cureus · doi:10.7759/cureus.39568 · Cited by 12
Delineating conditions and subtypes in chronic pain using neuroimaging
Holmes, S. A., Upadhyay, J., & Borsook, D. (2019) · PAIN Reports · doi:10.1097/pr9.0000000000000768 · Cited by 11
Efficacy and Safety of a Novel Herbal Medicine in the Treatment of Irritable Bowel Syndrome: A Randomized Double-Blinded Clinical Trial
Bordbar, G., Miri, M., Omidi, M., Shoja, S., & Akhavan, M. (2020) · Gastroenterology Research and Practice · doi:10.1155/2020/8213082 · Cited by 13
Effect of Probiotics in Stress-Associated Constipation Model in Zebrafish (Danio rerio) Larvae
Lee, A., Kim, S. Y., Kang, S., Kang, S. H., Kim, D., Choe, J. W., Hyun, J. J., Jung, S. W., Jung, Y. K., Koo, J. S., et al. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25073669 · Cited by 12
Eluxadoline for the treatment of diarrhoea-predominant irritable bowel syndrome
Scarpellini, E., Laterza, L., Ianiro, G., Tack, J., Abenavoli, L., & Gasbarrini, A. (2016) · Expert Opinion on Pharmacotherapy · doi:10.1080/14656566.2016.1182982 · Cited by 13
“One Flare at a Time”
Skrastins, O., & Fletcher, P. C. (2016) · Clinical Nurse Specialist · doi:10.1097/nur.0000000000000229 · Cited by 11
Adverse Childhood Experiences and Their Effect on Irritable Bowel Syndrome Among Saudi Arabian Adults
Alsubaie, M. A., Alkhalifah, H. A., Ali, A. H., Bahabri, M. A., Alharbi, B. A., & Alfakeh, S. A. (2022) · Cureus · doi:10.7759/cureus.25791 · Cited by 11
Comparison of Resilience and Psychological Wellbeing in Women with Irritable Bowel Syndrome and Normal Women
Shahdadi, H., Balouchi, A., & Shaykh, A. (2017) · Materia Socio Medica · doi:10.5455/msm.2017.29.105-108 · Cited by 13
Gender and Weight Influence Quality of Life in Irritable Bowel Syndrome
Sherwin, L. B., Ozoji, O., Boulineaux, C. M., Joseph, P. V., Fourie, N. H., Abey, S. K., Zhang, X., & Henderson, W. A. (2017) · Journal of Clinical Medicine · doi:10.3390/jcm6110103 · Cited by 11
Epidemiology of Irritable Bowel Syndrome: A Systematic Review and Meta-Analysis
Li, C., Ying, Y., Zheng, Y., Li, X., & Lan, L. (2024) · Epidemiology and Public Health · doi:10.52768/epidemiolpublichealth/1034 · Cited by 10
An 8-Week Course of Bifidobacterium longum 35624® Is Associated with a Reduction in the Symptoms of Irritable Bowel Syndrome
Lenoir, M., Wienke, J., Fardao-Beyler, F., & Roese, N. (2023) · Probiotics and Antimicrobial Proteins · doi:10.1007/s12602-023-10151-w · Cited by 10
Serine proteases and metalloproteases are highly increased in irritable bowel syndrome Tunisian patients
Soussou, S., Jablaoui, A., Mariaule, V., Kriaa, A., Boudaya, H., Wysocka, M., Amouri, A., Gargouri, A. F., Lesner, A., Maguin, E., et al. (2023) · Scientific Reports · doi:10.1038/s41598-023-44454-3 · Cited by 16
Effect of video-assisted patient education on compliance with therapy, quality of life, psychomorbidity, and cost of illness in irritable bowel syndrome
Kamat, N., Mallayasamy, S. R., Sharma, P., Kamath, A., & Pai, C. G. (2018) · Postgraduate Medicine · doi:10.1080/00325481.2019.1549458 · Cited by 10

Authors: Soares, R. L.
Venue: World Journal of Gastroenterology
Publisher: Baishideng Publishing Group Inc.
Published: 2014
Volume: 20
Issue: 34
Pages: 12144
ISSN: 1007-9327 (ISSN-L)
DOI: 10.3748/wjg.v20.i34.12144
PMC: PMC4161800
OpenAlex: W2040223383
Cited by: 266
References: 271
Citations by year: 2026: 12 · 2025: 15 · 2024: 16 · 2023: 38 · 2022: 26 · 2021: 28 · 2020: 24 · 2019: 23 · 2018: 21 · 2017: 22 · 2016: 24 · 2015: 16 · 2014: 1
FWCI: 3.49
Type: journal article
Language: en
Open access: hybrid
doi.org
Licence: cc-by-nc
Locations: World Journal of Gastroenterology (publishedVersion, cc-by-nc)
Europe PMC (PubMed Central) (publishedVersion)
PubMed Central (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Gastroenterology › Gastrointestinal motility and disorders
Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Infant Health and Development
Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gut microbiota and health
Keywords: irritable bowel syndrome, Rome criteria, biopsychosocial model, IBS pathophysiology, IBS diagnosis, non-pharmacological treatment, pharmacotherapy, physician-patient relationship, quality of life, prevalence
MeSH terms: Combined Modality Therapy, Humans, Predictive Value of Tests, Risk Factors, Prevalence, Treatment Outcome, Irritable Bowel Syndrome

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Irritable bowel syndrome: A clinical review

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks