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Cited by 667

The DOI matches its Crossref record; 9 of the 9 references it cites were found in a registry or an index.

A review of new developments in the Friedel–Crafts alkylation – From green chemistry to asymmetric catalysis

Open access
Rueping, Magnus, Nachtsheim, Boris J·2010·Beilstein Journal of Organic Chemistry

Abstract

The development of efficient Friedel–Crafts alkylations of arenes and heteroarenes using only catalytic amounts of a Lewis acid has gained much attention over the last decade. The new catalytic approaches described in this review are favoured over classical Friedel–Crafts conditions as benzyl-, propargyl- and allyl alcohols, or styrenes, can be used instead of toxic benzyl halides. Additionally, only low catalyst loadings are needed to provide a wide range of products. Following a short introduction about the origin and classical definition of the Friedel–Crafts reaction, the review will describe the different environmentally benign substrates which can be applied today as an approach towards greener processes. Additionally, the first diastereoselective and enantioselective Friedel–Crafts-type alkylations will be highlighted.

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Metadata

Authors
Rueping, M., & Nachtsheim, B. J.
Venue
Beilstein Journal of Organic Chemistry
Published
2010-01-20
Volume
6
Pages
6-6
ISSN
1860-5397 (ISSN-L)
OpenAlex
W2009170287
Cited by
667
References
9
FWCI
12.30
Type
journal article
Language
en
Open access
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CoChat. (2026). Citation check: A review of new developments in the Friedel–Crafts alkylation – From green chemistry to asymmetric catalysis. https://app.cochat.ai/papers/10.3762/bjoc.6.6
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Rueping, M., & Nachtsheim, B. J. (2010). A review of new developments in the Friedel–Crafts alkylation – From green chemistry to asymmetric catalysis. Beilstein Journal of Organic Chemistry. https://doi.org/10.3762/bjoc.6.6

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.