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Cited by 207Pharmacology and Obesity TreatmentBariatric Surgery and OutcomesObesity, Physical Activity, Diet

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A review of current guidelines for the treatment of obesity

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Marc‐André Cornier·2022·The American Journal of Managed Care
DOI 10.37765/ajmc.2022.89292
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Abstract

Two guidelines-one by the American College of Cardiology (ACC)/American Heart Association (AHA)/The Obesity Society (TOS), and the other by the American Association of Clinical Endocrinologists (AACE)/American College of Endocrinology (ACE)-remain the standard of care in the management of overweight and obesity in adults. However, since the publication of the ACC/AHA/TOS document, several relevant pharmacotherapies have been approved by the FDA, a medication was withdrawn from the market, and several procedures and device types for weight loss have been recommended or FDA-approved. Simultaneously, research in obesity treatment has advanced, and leaders in the field have issued complementary guidance. This article summarizes and synthesizes the 2013 ACC/AHA/TOS and the 2016 AACE/ACE guidelines and includes updates from more recent professional association guidance. Measurement of body mass index is recommended to initiate evaluation for overweight and obesity and determine disease classification. To stage disease severity, weight-related conditions should be assessed. Although lifestyle therapy remains the cornerstone of treatment for this disease, both pharmacotherapy and metabolic and bariatric surgery produce greater and more sustained weight loss in treatment-approved populations as compared with lifestyle modifications alone. An ongoing partnership between the patient and clinician is highly recommended to manage this serious, progressive, chronic disease.

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  1. Cornier MA. a review of current guidelines for the treatment of obesity. Am J Manag Care. 2022;28(suppl 15):S288-S296. doi:10.37765/ajmc.2022.89292
  2. Yuen M, Earle R, Kadambi N, et al. A systematic review and evaluation of current evidence reveals 195 obesity-associated disorders (OBAD). Poster presented at: ObesityWeek 2016; October 31 to November 4, 2016; New Orleans, LA. Poster T-P-3166.
  3. Overweight and obesity. Healthy People 2030. US Department of Health and Human Services. Accessed July 22, 2022. https://health.gov/healthypeople/objectives-and-data/browse-objectives/ overweight-and-obesity 62. Addressing obesity D-440.954. American Medical Association. 2022. Accessed November 23, 2022. https://policysearch.ama-assn.org/policyfinder/detail/obesity?uri=%2FAMADoc%2Fdirectives.xml-0-1498.xml
  4. Garvey WT, Mechanick JI, Brett EM, et al; Reviewers of the AACE/ACE Obesity Clinical Practice Guidelines. American Association of Clinical Endocrinologists and American College of Endocrinology comprehensive clinical practice guidelines for medical care of patients with obesity. Endocr Pract. 2016;22(suppl 3):1-203. doi:10.4158/EP161365.GL · DOI
  5. Jensen MD, Ryan DH, Apovian CM, et al; American College of Cardiology/American Heart Association Task Force on Practice Guidelines; Obesity Society. 2013 AHA/ACC/TOS guideline for the management of overweight and obesity in adults: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and The Obesity Society. Circulation. 2014;129(25; suppl 2):S102-S138. doi:10.1161/01.cir.0000437739.71477.ee · DOI
  6. Yuen M, Earle R, Kadambi N et al. A systematic review and evaluation of current evidence reveals 195 obesity-associated disorders (OBAD). Poster presented at: ObesityWeek 2016; October 31-November 4, 2016; New Orleans, LA. Poster T-P-3166.
  7. Cornier MA. A review of current guidelines for the treatment of obesity. Am J Manag Care. 2022;28(suppl 15):S288-S296. doi:10.37765/ajmc.2022.89292
  8. Kompaniyets L, Goodman AB, Belay B, et al. Body mass index and risk for COVID-19-related hospital- ization, intensive care unit admission, invasive mechanical ventilation, and death-United States, March- December 2020. MMWR Morb Mortal Wkly Rep. 2021;70(10):355-361. doi:10.15585/mmwr.mm7010e4 · DOI
  9. Aminian A, Bena J, Pantalone KM, Burguera B. Association of obesity with postacute sequelae of COVID-19. Diabetes Obes Metab. 2021;23(9):2183-2188. doi:10.1111/dom.14454 · DOI
  10. part B):2985-3023. doi:10.1016/j.jacc.2013.11.004 · DOI · Paper page
  11. Garvey WT, Mechanick JI, Brett EM, et al; Reviewers of the AACE/ACE Obesity Clinical Practice Guidelines. American Association of Clinical Endocrinologists and American College of Endocrinology comprehensive clinical practice guidelines for medical care of patients with obesity. Endocr Pract. 2016;22(suppl 3):1-203. doi:10.4158/EP161365.GL · DOI
  12. Bray GA, Kim KK, Wilding JPH; World Obesity Federation. Obesity: a chronic relapsing progressive disease process. A position statement of the World Obesity Federation. Obes Rev. 2017;18(7):715-723. doi:10.1111/obr.12551 · DOI · Paper page
  13. Bays HE, Shrestha A, Niranjan V, Khanna M, Kambhamettu L. Obesity pillars roundtable: obesity and South Asians. Obes Pillars. 2022;1(10006). doi.org/10.1016/j.obpill.2021.100006 · DOI
  14. Yu CK, Teoh TG, Robinson S. Obesity in pregnancy. BJOG. 2006;113(10):1117-1125. doi:10.1111/j.1471- 0528.2006.00991.x · DOI
  15. Apovian CM, Aronne LJ, Bessesen DH, et al. Pharmacological management of obesity: an endocrine Society clinical practice guideline. J Clin Endocrinol Metab. 2015;100(2):342-362. doi:10.1210/jc.2014- 3415. doi:10.1210/jc.2015-1782 · DOI · Paper page
  16. Grunvald E, Shah R, Hernaez R, et al. AGA clinical practice guideline on pharmacological interventions for adults with obesity. Gastroenterology. 2022;163(5):1198-1225. doi:10.1053/j.gastro.2022.08.045 · DOI · Paper page
  17. Eisenberg D, Shikora SA, Aarts E, et al. 2022 American Society for Metabolic and Bariatric Surgery (ASMBS) and International Federation for the Surgery of Obesity and Metabolic Disorders (IFSO): indications for metabolic and bariatric surgery. Surg Obes Relat Dis. 2022. Published online October 18, 2022. doi:10.1016/j.soard.2022.08.013 REFERENCES · DOI · Paper page
  18. Garvey WT, Mechanick JI, Brett EM, et al; Reviewers of the AACE/ACE Obesity Clinical Practice Guidelines. American Association of Clinical Endocrinologists and American College of Endocrinology comprehensive clinical practice guidelines for medical care of patients with obesity. Endocr Pract. 2016;22(suppl 3):1-203. doi:10.4158/EP161365.GL · DOI
  19. Jensen MD, Ryan DH, Apovian CM, et al; American College of Cardiology/American Heart Association Task Force on Practice Guidelines; Obesity Society. 2013 AHA/ACC/TOS guideline for the management of overweight and obesity in adults: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and The Obesity Society. J Am Coll Cardiol. 2014;63(25; part B):2985-3023. doi:10.1016/j.jacc.2013.11.004 · DOI · Paper page
  20. Apovian CM, Aronne LJ, Bessesen DH, et al. Pharmacological management of obesity: an Endocrine Society clinical practice guideline. J Clin Endocrinol Metab. 2015;100(2):342-362. doi:10.1210/jc.2014-3415. · DOI · Paper page
  21. Mechanick JI, Apovian C, Brethauer S, et al. Clinical practice guidelines for the perioperative nutri- tion, metabolic, and nonsurgical support of patients undergoing bariatric procedures -2019 update: cosponsored by American Association of Clinical Endocrinologists/American College of Endocrinology, The Obesity Society, American Society for Metabolic & Bariatric Surgery, Obesity Medicine Association, and American Society of Anesthesiologists. Surg Obes Relat Dis. 2020;16(2):175-247. doi:10.1016/j. soard.2019.10.025 · DOI · Paper page
  22. Shetye B, Hamilton FR, Bays HE. Bariatric surgery, gastrointestinal hormones, and the microbi- ome: an Obesity Medicine Association (OMA) Clinical Practice Statement (CPS) 2022. Obesity Pillars. 2022;2(1):1-20. doi:10.1016/j.obpill.2022.100015 · DOI
  23. Grunvald E, Shah R, Hernaez R, et al. AGA clinical practice guideline on pharmacological interventions for adults with obesity. Gastroenterology. 2022;163(5):1198-1225. doi:10.1053/j.gastro.2022.08.045 · DOI · Paper page
  24. Cornier MA. A review of current guidelines for the treatment of obesity. Am J Manag Care. 2022;28(suppl 15):S288-S296. doi:10.37765/ajmc.2022.89292 REFERENCES
  25. Massie DC, Amaro A, Kaplan M. Patient well-being and the clinical and economic burdens associated with obesity in the United States. Am J Manag Care. 2022;28(suppl 15):S279-S287. doi:10.37765/ajmc.2022.89291 · DOI
  26. Cornier MA. A review of current guidelines for the treatment of obesity. Am J Manag Care. 2022;28(suppl 15):S288-S296. doi:10.37765/ajmc.2022.89292
  27. Kyrillos J. Semaglutide 2.4-mg injection as a novel approach for chronic weight management. Am J Manag Care. 2022;28(suppl 15):S297-S306. doi:10.37765/ajmc.2022.89293 · DOI · Paper page
  28. Garvey WT, Mechanick JI, Brett EM, et al; Reviewers of the AACE/ACE Obesity Clinical Practice Guidelines. American Association of Clinical Endocrinologists and American College of Endocrinology comprehensive clinical practice guidelines for medical care of patients with obesity. Endocr Pract. 2016;22(suppl 3):1-203. doi:10.4158/EP161365.GL · DOI
  29. Jensen MD, Ryan DH, Apovian CM, et al; American College of Cardiology/American Heart Association Task Force on Practice Guidelines; Obesity Society. 2013 AHA/ACC/TOS guideline for the management of overweight and obesity in adults: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and The Obesity Society. J Am Coll Cardiol. 2014;63(25; pt B):2985-3023. doi:10.1016/j.jacc.2013.11.004 · DOI · Paper page
  30. Apovian CM, Aronne LJ, Bessesen DH, et al; Endocrine Society. Pharmacological management of obesity: an Endocrine Society clinical practice guideline. J Clin Endocrinol Metab. 2015;100(2):342-362. doi:10.1210/jc.2014-3415 · DOI · Paper page
  31. Carlsson LMS, Sjöholm K, Jacobson P, et al. Life expectancy after bariatric surgery in the Swedish obese subjects study. N Engl J Med. 2020;383(16):1535-1543. doi:10.1056/NEJMoa2002449 · DOI · Paper page
  32. Eisenberg D, Shikora SA, Aarts E, et al. 2022 American Society for Metabolic and Bariatric Surgery (ASMBS) and International Federation for the Surgery of Obesity and Metabolic Disorders (IFSO): indications for metabolic and bariatric surgery. Surg Obes Relat Dis. Published online October 18, 2022. doi:10.1016/j.soard.2022.08.013 · DOI · Paper page
  33. Ma IT, Madura JA 2nd. Gastrointestinal complications after bariatric surgery. Gastroenterol Hepatol (NY). 2015;11(8):526-535.
  34. Grunvald E, Shah R, Hernaez R, et al; AGA Clinical Guidelines Committee. AGA clinical practice guide- line on pharmacological interventions for adults with obesity. Gastroenterology. 2022;163(5):1198-1225. doi:10.1053/j.gastro.2022.08.045 · DOI · Paper page
  35. Atlas SJ, Kim K, Beinfeld M, et al. Medications for Obesity Management: Effectiveness and Value; Evidence Report. Institute for Clinical and Economic Review. August 31, 2022. Accessed October 5, 2022. https://icer.org/assessment/obesity-management-2022/ 27. Belviq, Belviq XR (lorcaserin) by Eisai: drug safety communication -FDA requests withdrawal of weight-loss drug. FDA. February 13, 2020. Accessed October 21, 2022. https://www.fda.gov/safety/ medical-product-safety-information/belviq-belviq-xr-lorcaserin-eisai-drug-safety-communication-fda- requests-withdrawal-weight-loss-drug 28. Xenical. Prescribing information. CHEPLAPHARM Arzneimittel GmbH/H2-Pharma; 2017. Accessed July 22, 2022. https://xenical.com/pdf/PI_Xenical-brand_FINAL.PDF
  36. Kaplan LM, Golden A, Jinnett K, et al. Perceptions of barriers to effective obesity care: results from the national ACTION study. Obesity (Silver Spring). 2018;26(1):61-69. doi:10.1002/oby.22054 · DOI · Paper page
  37. Kyle TK, Dhurandhar EJ, Allison DB. Regarding obesity as a disease: evolving policies and their implications. Endocrinol Metab Clin North Am. 2016;45(3):511-520. doi:10.1016/j.ecl.2016.04.004 · DOI · Paper page
  38. Resolution in support of efforts to reduce the incidence of obesity and chronic disease. National Conference of Insurance Legislators. July 29, 2015. Accessed October 4, 2022. http://ncoil.org/wp- content/uploads/2016/04/07232015ObesityResolution.pdf
  39. Waidmann TA, Waxman E, Pancini V, Gupta P, Tabb LP. Obesity across America: geographic variation in disease prevalence and treatment options. Urban Institute. February 17, 2022. Accessed July 22, 2022. https://www.urban.org/research/publication/obesity-across-america 41. Rubino F, Puhl RM, Cummings DE, et al. Joint international consensus statement for ending stigma of obesity. Nat Med. 2020;26(4):485-497. doi:10.1038/s41591-020-0803-x · DOI · Paper page
  40. Mechanick JI, Apovian C, Brethauer S, et al. Clinical practice guidelines for the perioperative nutrition, metabolic, and nonsurgical support of patients undergoing bariatric procedures -2019 update: cospon- sored by American Association of Clinical Endocrinologists/American College of Endocrinology, The Obesity Society, American Society for Metabolic & Bariatric Surgery, Obesity Medicine Association, and American Society of Anesthesiologists. Surg Obes Relat Dis. 2020;16(2):175-247. doi:10.1016/j.soard.2019.10.025 · DOI · Paper page
  41. National Academies of Sciences, Engineering, and Medicine 2019. A health equity approach to obesity efforts: proceedings of a workshop in brief. National Academies Press. https://nap.nationalacademies. org/catalog/25496/a-health-equity-approach-to-obesity-efforts-proceedings-of-a 57. About social determinants of health (SDOH). Centers for Disease Control and Prevention. March 10, 2021. Accessed July 22, 2022. https://www.cdc.gov/socialdeterminants/about.html
  42. Grover SA, Kaouache M, Rempel P, et al. Years of life lost and healthy life-years lost from diabetes and cardiovascular disease in overweight and obese people: a modelling study. Lancet Diabetes Endocrinol. 2015;3(2):114-122. doi:10.1016/S2213-8587(14)70229-3 · DOI
  43. Su W, Huang J, Chen F, Mocarski M, Dall TM, Perrault L. Modeling the clinical and economic implications of obesity using microsimulation. J Med Econ. 2015;18(11):886-897. doi:10.3111/1369699 8.2015.1058805 · DOI · Paper page
  44. Kushner RF, Calanna S, Davies M, et al. Semaglutide 2.4 mg for the treatment of obesity: key ele- ments of the STEP trials 1 to 5. Obesity (Silver Spring). 2020;28(6):1050-1061. doi:10.1002/oby.22794 · DOI · Paper page
  45. Wilding JPH, Batterham RL, Calanna S, et al. Once-weekly semaglutide in adults with overweight or obesity. N Engl J Med. 2021;384(11):989-1002. doi:10.1056/NEJMoa2032183 · DOI · Paper page
  46. Davies M, Færch L, Jeppesen OK, et al; STEP 2 Study Group. Semaglutide 2.4 mg once a week in adults with overweight or obesity, and type 2 diabetes (STEP 2): a randomized, double-blind, double- dummy, placebo-controlled, phase 3 trial. Lancet. 2021;397(10278):971-984. doi:10.1016/S0140- 6736(21)00213-0 · DOI · Paper page
  47. Wadden TA, Bailey TS, Billings LK, et al; STEP 3 Investigators. Effect of subcutaneous semaglutide vs placebo as an adjunct to intensive behavioral therapy on body weight in adults with overweight or obesity: the STEP 3 randomized clinical trial. JAMA. 2021;325(14):1403-1413. doi:10.1001/jama.2021.1831 · DOI · Paper page
  48. Rubino D, Abrahamsson N, Davies M, et al; Step 4 Investigators. Effect of continued weekly subcuta- neous semaglutide vs placebo on weight loss maintenance in adults with overweight or obesity: the STEP 4 randomized clinical trial. JAMA. 2021;325(14):1414-1425. doi:10.1001/jama.2021.3224 · DOI · Paper page

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Metadata

Authors
Cornier, M.
Affiliations
Medical University of South Carolina (US)
Corresponding author
Marc‐André Cornier
Venue
The American Journal of Managed Care
Publisher
Managed Care and Healthcare Communications, LLC
Published
2022-12-01
Volume
28
Issue
Suppl 15
Pages
S288-S296
ISSN
  • 1088-0224 (ISSN-L)
  • 1936-2692
DOI
10.37765/ajmc.2022.89292
OpenAlex
W4311890439
Cited by
207
References
0
Citations by year
2026: 32 · 2025: 79 · 2024: 75 · 2023: 21
FWCI
6.27
Type
journal article
Language
en
Open access
Locations
  • The American Journal of Managed Care (publishedVersion)
  • PubMed (publishedVersion)
Funders
  • Eli Lilly and Company
  • Novo Nordisk
Topics
  • Health Sciences › Medicine › Pharmacology (medical) › Pharmacology and Obesity Treatment
  • Health Sciences › Medicine › Surgery › Bariatric Surgery and Outcomes
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Obesity, Physical Activity, Diet
Keywords
obesity treatment, obesity pharmacotherapy, bariatric surgery, metabolic surgery, lifestyle therapy, body mass index, obesity staging, weight-related comorbidities, patient-provider partnership
MeSH terms
Endocrinologists, Adult, Humans, Obesity, United States, Weight Loss, Body Mass Index, Overweight

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