Ascaris lumbricoides infection: Still a threat for iron deficiency anaemia in 2-year-old Bangladeshi slum-dwelling children
Open accessAbstract
INTRODUCTION: Although parasitic infections lead to extracorporeal iron loss resulting in iron deficiency anaemia (IDA), data associating IDA with parasitic infections in the first two years of life are limited. We sought to evaluate the prevalence and severity of anaemia and IDA during this period and to investigate the association between intestinal parasitic infections and IDA. METHODOLOGY: Data was collected under MAL-ED study protocol in Bauniabadh slum of Dhaka, Bangladesh. The presence of parasites in stool was detected using wet preparation microscopy at 7, 15, and 24 months. Anaemia was defined as serum haemoglobin < 11 g/dL and IDA was defined by serum haemoglobin < 11 g/dL, serum ferritin < 12 g/L and soluble transferrin receptor > 8.3 mg/L. Logistic regression was done to quantify the relation between stool parasite and IDA separately on samples collected at 7, 15 and 24 months. RESULTS: 265 children were enrolled after birth and samples were collected at 7, 15 and 24 months. Anaemia was detected at 7, 15 and 24 months in 117 (48.8%), 106 (44.2%) and 67 (27.9%) cases whereas IDA was found in 15 (6.3%), 47 (19.6%) and 39 (16.3%) cases, respectively. Iron deficiency anaemia at 24 months was significantly associated with Ascaris lumbricoides infection (OR 3.76; 95 % CI, 1.08-13.11). CONCLUSIONS: The prevalence of anaemia and IDA in slum dwelling children of Dhaka is high and Ascaris lumbricoides infection was found to have a strong association with IDA at 24 months of age.
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Several studies have shown a relationship between ascariasis and iron-deficiency anaemia (IDA).
“Several studies had shown the relationship between ascariasis and iron-deficiency anaemia (IDA) [64,65].”
From Intestinal Parasitic Infection and Nutritional Status in Children under Five Years Old: A Systematic Review (2022) · cites this paper as [64]
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Cites
Worldwide prevalence of anaemia 1993-2005: WHO global database on anaemia.
de Benoist, B., McLean, E., Egll, I., & Cogswell, M. E. (2008) · Cited by 1,543 · see citing works
A review of studies on the effect of iron deficiency on cognitive development in children
Grantham-McGregor, S., & Ani, C. (2001) · The Journal of Nutrition · doi:10.1093/jn/131.2.649s · Cited by 1,293 · see citing works
Waterborne transmission of protozoan parasites: Review of worldwide outbreaks - An update 2011–2016
Efstratiou, A., Ongerth, J. E., & Karanis, P. (2017) · Water Research · doi:10.1016/j.watres.2017.01.036 · Cited by 1,109 · see citing works
The prevalence of anaemia in the world.
Demaeyer, E. M., & Adiels-Tegman, M. (1985) · PubMed · Cited by 808 · see citing works
Iron Deficiency in Infancy and Childhood
Desforges, J. F., & Oski, F. A. (1993) · New England Journal of Medicine · doi:10.1056/nejm199307153290308 · Cited by 798 · see citing works
Iron deficiency in infancy and childhood
Dallman, P. R., Siimes, M. A., & Stekel, A. (1980) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/33.1.86 · Cited by 421 · see citing works
Mehraj, V., Hatcher, J., Akhtar, S., Rafique, G., & Beg, M. A. (2008) · PLoS ONE · doi:10.1371/journal.pone.0003680 · Cited by 264 · see citing works
Nutrition, Growth, and Complementary Feeding of The Brestfed Infant
Dewey, K. G. (2001) · Pediatric Clinics of North America · doi:10.1016/s0031-3955(05)70287-x · Cited by 264 · see citing works
Khan, J. R., Awan, N., & Misu, F. (2016) · BMC Pediatrics · doi:10.1186/s12887-015-0536-z · Cited by 190 · see citing works
Iron Deficiency: The Global Perspective
Cook, J. D., Skikne, B., & Baynes, R. D. (1994) · Advances in experimental medicine and biology · doi:10.1007/978-1-4615-2554-7_24 · Cited by 183 · see citing works
Iron deficiency anemia from diagnosis to treatment in children
Özdemir, N. (2015) · Türk Pediatri Arşivi · doi:10.5152/tpa.2015.2337 · Cited by 168 · see citing works
Iron Deficiency Anemia: Focus on Infectious Diseases in Lesser Developed Countries
Shaw, J. G., & Friedman, J. F. (2011) · Anemia · doi:10.1155/2011/260380 · Cited by 161 · see citing works
BREAST MILK IRON—A DECLINING CONCENTRATION DURING THE COURSE OF LACTATION
Siimes, M. A., Vuori, E., & KUITUNEN, P. (1979) · Acta Paediatrica · doi:10.1111/j.1651-2227.1979.tb04425.x · Cited by 150 · see citing works
Iron metabolism and vitamin A deficiency in children in northeast Thailand
Bloem, M. W., Wedel, M., Egger, R. J., Speek, A. J., Schrijver, J., Saowakontha, S., & Schreurs, W. H. P. (1989) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/50.2.332 · Cited by 147 · see citing works
Tomczyk, S. M., Deribe, K., Brooker, S. J., Clark, H., Rafique, K., Knopp, S., Utzinger, J., & Davey, G. (2014) · PLoS neglected tropical diseases · doi:10.1371/journal.pntd.0003285 · Cited by 91 · see citing works
Sarker, S. A., Mahmud, H., Davidsson, L., Alam, N. H., Ahmed, T., Alam, N., Salam, M. A., Beglinger, C., Gyr, N. E., & Fuchs, G. J. (2008) · Gastroenterology · doi:10.1053/j.gastro.2008.07.030 · Cited by 90 · see citing works
Self-citationIntestinal parasitic infections and micronutrient deficiency: a review.
Hesham, M. S., Edariah, A. B., & Norhayati, M. (2004) · PubMed · Cited by 87 · see citing works
The MAL-ED Cohort Study in Mirpur, Bangladesh
Ahmed, T., Mahfuz, M., Islam, M. M., Mondal, D., Hossain, M. I., Ahmed, A. M. S., Tofail, F., Gaffar, S. M. A., Haque, R., Guerrant, R. L., et al. (2014) · Clinical Infectious Diseases · doi:10.1093/cid/ciu458 · Cited by 82 · see citing works
Self-citationInfant Feeding Practices, Dietary Adequacy, and Micronutrient Status Measures in the MAL-ED Study
Caulfield, L. E., Bose, A., Chandyo, R. K., Nesamvuni, C. N., de Moraes, M. L., Turab, A., Patil, C. L., Mahfuz, M., Ambikapathi, R., Ahmed, T., et al. (2014) · Clinical Infectious Diseases · doi:10.1093/cid/ciu421 · Cited by 79 · see citing works
Self-citationIron Deficiency in Infancy and Childhood
Bothwell, T. H., Cook, J. D., & Formon, S. J. (1979) · Cited by 73 · see citing works
Gopalakrishnan, S., Eashwar, V. M. A., Muthulakshmi, M., et al. (2018) · Journal of Family Medicine and Primary Care · doi:10.4103/jfmpc.jfmpc_89_18 · Cited by 37 · see citing works
Prevalence of parasitic infections in a rural area of Karachi, Pakistan.
Siddiqui, M. I., Bilqees, F. M., Iliyas, M., et al. (2002) · PubMed · Cited by 36 · see citing works
Frequency of intestinal parasitic infestation in children of 5-12 years of age in Abbottabad.
Ahmed, A. K., Malik, B., Shaheen, B., Yasmeen, G., Dar, J. B., Mona, A. K., Gulab, S., & Ayub, M. (2003) · PubMed · Cited by 31 · see citing works
Zanin, F. H. C., da Silva, C. A. M., Bonomo, É., et al. (2015) · PLoS ONE · doi:10.1371/journal.pone.0139555 · Cited by 30 · see citing works
Faqih, A., Kakish, S. B., & Izzat, M. (2006) · Food and Nutrition Bulletin · doi:10.1177/156482650602700304 · Cited by 25 · see citing works
Reviewing Anemia and Iron Folic Acid Supplementation Program in Bangladesh - A Special Article
Rashid, M., Flora, M., Moni, M., et al. (1970) · Bangladesh Medical Journal · doi:10.3329/bmj.v39i3.9952 · Cited by 17 · see citing works
Arlette, J. P. (1982) · International Journal of Dermatology · doi:10.1111/j.1365-4362.1982.tb03179.x · Cited by 17 · see citing works
Intestinal Infestations in Under-Five Children in Zambia
Mwale, K. (2016) · International Journal of Maternal and Child Health and AIDS · doi:10.21106/ijma.62 · Cited by 16 · see citing works
Relationships between anaemia and parasitic infections in adolescent girls of Bangladesh
Banu, H., Khanum, H., & Hossain, M. A. (2015) · Bangladesh Journal of Zoology · doi:10.3329/bjz.v42i1.23340 · Cited by 12 · see citing works
Self-citationOverview of the nutrition situation in four countries in South and Central Asia.
Chaparro, C. M., Oot, L., & Sethuraman, K. (2014) · Cited by 11 · see citing works
Nyaruhucha, C., Mamiro, P., & Kerengi, A. (2009) · Tanzania journal of health research/Tanzania Journal of Health Research · doi:10.4314/thrb.v7i1.45106 · Cited by 7 · see citing works
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Fauziah, N., Aviani, J. K., Agrianfanny, Y. N., & Fatimah, S. N. (2022) · Tropical Medicine and Infectious Disease · doi:10.3390/tropicalmed7110371 · Cited by 122 · see citing works
“Several studies had shown the relationship between ascariasis and irondeficiency anaemia (IDA) [64,65].”
Background
- Authors
- Hossain, M. S., Das, S., Gazi, M. A., Mahfuz, M., & Ahmed, T.
- Affiliations
- International Centre for Diarrhoeal Disease Research (BD)
- Corresponding author
- Hossain, Md. Shabab
- Venue
- The Journal of Infection in Developing Countries
- Published
- 2019-10-31
- Volume
- 13
- Issue
- 10
- Pages
- 933-938
- ISSN
- 1972-2680 (ISSN-L)
- PMC
- PMC7722353
- OpenAlex
- W2982686061
- Cited by
- 13
- References
- 31
- Citations by year
- 2026: 1 · 2025: 2 · 2024: 1 · 2023: 5 · 2022: 3 · 2021: 1
- FWCI
- 0.77
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Locations
- The Journal of Infection in Developing Countries (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion)
- ResearchSpace (University of Auckland) (submittedVersion, cc-by)
- Greater South Information System
- Funders
- International Centre for Diarrhoeal Disease Research, Bangladesh
- Topics
- Life Sciences › Immunology and Microbiology › Parasitology › Parasites and Host Interactions
- Health Sciences › Nursing › Nutrition and Dietetics › Child Nutrition and Water Access
- Health Sciences › Medicine › Hematology › Iron Metabolism and Disorders
- Keywords
- Ascaris lumbricoides, intestinal parasitic infections, iron deficiency anemia, anemia prevalence, young children, urban slums, Dhaka, serum ferritin, soluble transferrin receptor
- MeSH terms
- Animals, Ascariasis, Bangladesh, Child, Preschool, Female, Humans, Infant, Infant, Newborn, Male, Poverty Areas, Prevalence, Ascaris lumbricoides, Anemia, Iron-Deficiency
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