Activation of STAT3 is a marker of poor prognosis in human colorectal cancer

Kusaba, Takafumi, Nakayama, Toshiyuki, Yamazumi, Kazuyuki, Yakata, Yuichi, Yoshizaki, Ayumi, Inoue, Kenichiro, Nagayasu, Takeshi, Sekine, Ichiro·2006·Oncology Reports
DOI 10.3892/or.15.6.1445

Cited by (238)

Items 201–238 of 238

  1. Universal and Specific Functions of STAT3 in Solid Tumours
    Lidia Avalle, Gabriella Regis, Valeria Poli · 2012 · Springer eBooks
  2. Cancer Stem Cell and Gastrointestinal Cancer: Current Status, Targeted Therapy and Future Implications
    Rizwan Ahmad, Punita Dhawan · 2015 · Biochemistry & Pharmacology Open Access
  3. Dienogest attenuates STAT3 activation in ovarian endometriotic cysts
    JongYeob Choi, MinWha Jo, Eunyoung Lee, Sung Eun Kim, Dong‐Yun Lee, DooSeok Choi · 2024 · European Journal of Obstetrics & Gynecology and Reproductive Biology
  4. Zinc finger protein 263 promotes colorectal cancer cell progression by activating STAT3 and enhancing chemoradiotherapy resistance
    Yadan Du, Ya‐Wen Chen, Zaihua Yan, Jian Yang, Mingxu Da · 2024 · Scientific Reports
  5. Rhus verniciflua Stokes extract suppresses migration and invasion in human gastric adenocarcinoma AGS cells
    Hyun Sook Lee, Jae In Jung, Kyeong-Hee Kim, Sang Jae Park, Eun Ji Kim · 2020 · Nutrition Research and Practice
  6. Pentoxifylline: A Potent Inhibitor of Angiogenesis via Blocking STAT3 Signaling in B16F10 Melanoma
    Pratibha Dhumale, Yuvraj Nikam, Rajiv P. Gude · 2013 · International Journal of Tumor Therapy
  7. Nonreceptor Tyrosine Kinases
    David J. Matthews, Mary E. Gerritsen · 2010 · Wiley eBooks
  8. Mechanistic prediction and validation of Brevilin A Therapeutic effects in Lung Cancer
    Ruixue Wang, Cuiyun Gao, Yu Meng, Jialing Song, Zhenzhen Feng, Ruyu Wang, Huafeng Pan, Haimeng Liu, Wei Li, Xiangzhen Fan · 2024 · BMC Complementary Medicine and Therapies
  9. Comprehensive analysis of the prognostic and immunotherapeutic implications of STAT family members in human colorectal cancer
    Dingchang Li, Yanan Jiao, Wenxing Gao, Shidong Hu, Dingling Li, Wen Zhao, Peng Chen, Lujia Jin, Yingjie Zhao, Zhaofu Ma et al. · 2022 · Frontiers in Genetics
  10. Antitumor effect of toosendanin on oral squamous cell carcinoma via suppression of p-STAT3
    Ye Wu, Ling‐Ling Chen, Cheng Feng, Tao Wang, Shaohai He, Dali Zheng, Lisong Lin · 2023 · BMC Oral Health
  11. EPHA5 promotes cell proliferation and inhibits apoptosis in Follicular Thyroid Cancer via the STAT3 signaling pathway
    Guo-Rong Wang, Gao-Ran Xu, Yanan Fan, Guang-Zhi Wang, Jing-Chao Xu, Ning Zhang, Junzhu Chen, Huan-Jie Chen, Zhoufan Li, Xian-Wang Cao et al. · 2025 · Oncogenesis
  12. Gene expression profiling in Venous thromboembolism: Insights from publicly available datasets
    Sunanda Arya, Rashi Khare, Iti Garg, Swati Srivastava · 2024 · Computational Biology and Chemistry
  13. Expression of the signal transducer and activator of transcription factor 3 and Janus kinase 3 in colorectal carcinomas, colonic adenomas and ulcerative colitis
    Mohamed Moustafa Shareef, Maha Mostafa Shamloula, Asem Ahmed Elfert, Mohamed Ibrahim Elsawaf, Hanan Hamed Soliman · 2009 · Arab Journal of Gastroenterology
  14. Role of CTLA4 and pSTAT3 Immunostaining in Colorectal Carcinoma Prognosis and Treatment
    Dina Mohamed Allam, Hend Ahmed Kasem, Amira H Hegazy, Shereen Fathy Mahmoud · 2024 · Iranian journal of pathology
  15. EGFR ‐ STAT3 activation provides a therapeutic rationale for targeting aggressive ETV1 ‐positive prostate cancer
    Edson Paiva, Bernardo Orr, Ana Azeredo, Andreia Brandão, Manuel Rodrigues Teixeira, Paula Paulo · 2025 · Molecular Oncology
  16. A novel variant on chromosome 6p21.1 is associated with the risk of developing colorectal cancer: a two-stage case-control study in Han Chinese
    Chunxiao Xu, Dan Zhou, Feixia Pan, Yi Liu, Dandan Zhang, Aifen Lin, Xiaoping Miao, Yaqin Ni, Duo Lv, Shuai Zhang et al. · 2016 · BMC Cancer
  17. Biological and Exploitable Crossroads for the Immune Response in Cancer and COVID-19
    Letizia Vitali, Alessandra Merlini, Federica Galvagno, Alessia Proment, Dario Sangiolo · 2022 · Biomedicines
  18. The Role of the JAK/STAT Signalling Pathway in Immunoregulation of Gastrointestinal Cancers
    Kris Vaddi · 2017 · Springer eBooks
  19. RTA activates the activity of the miR-155 promoter region and promotes the growth and invasion of endothelial cells through the regulatory network of miR-155/GATA3/STAT3
    Yangyang Pan, Jun Zheng, Zuodong Ren, Wumei Yuan, Juan Zhao, Chunfu Zheng, Yan Zeng · 2025 · International Journal of Biological Macromolecules
  20. Discovery of SD-2301 as a Highly Potent and Selective PROTAC STAT3 Degrader Capable of Achieving Complete Tumor Regression with Single Administration
    Ranjan Kumar Acharyya, Longchuan Bai, Haibin Zhou, Dimin Wu, Mi Wang, Hoda Metwally, Donna McEachern, Meilin Wang, Bo Wen, Duxin Sun et al. · 2026 · Journal of Medicinal Chemistry
  21. Protein Expression of STAT3, pSTAT3, MMP-7 and VEGF in Colorectal Adenocarcinoma: An Immunohistochemical Study
    Rakesh Naidu, Lim Vin Nee, Mak Joon Wah, Kevin Moissinac, A. Rahman A. Jamal, Isabelle Rose, Yunus Alif Gul, Patricia Lim Kim Chooi, G. J. S. Tan · 2014 · Journal of Cancer Therapy
  22. Pleiotropic Action of Selenium in the Prevention and Treatment of Cancer, and Related Diseases
    Youcef M. Rustum · 2019 · MDPI eBooks
  23. Teaching and learning in practice. 7. Assessment in learning (ii). Assessment and learning outcomes (continuing education credit).
    D Stoker, Cathy Hull · 1994 · PubMed
  24. WITHDRAWN: Intrinsic molecular characteristics of inhibiting STAT3 activation and dimerization through targeting the phosphotyrosine binding site within the SH2 domain—A molecular dynamics study
    Yubo Fan, Ren Kong, David John Tweardy, Stephen T. C. Wong · 2013 · Journal of Structural Biology
  25. IL6 Gene Polymorphism and Oral Cancer: A Review
    Mehwish Zafar, Naila Hadi, Saeeda Baig · 2024 · DOAJ (DOAJ: Directory of Open Access Journals)
  26. Signal Transducer and Activator of Transcription of 5A and S3 (STAT5 and STATS3)
    Ali Salajegheh · 2016 · Springer eBooks
  27. A BALANCING ACT BETWEEN THE 'SRC-STAT3' AND 'P53- CALDESMON' PATHWAYS DICTATES THE OUTCOME OF SRC- INDUCED INVASIVE PHENOTYPES
    Patrick Mooney · 2010
  28. Precision oncology : oncogenic stat3 signalling in brain tumours
    Melanie Si Yan Tan · 2019
  29. Blockade of IL-6 inhibits tumor immune evasion and improves anti–PD-1 immunotherapy
    Wenhui Ma, Wenyi Li, Zhaokun Wu, Chaoting Zhang, Mingzhen Cheng, Yuehong Chen, Yini Zou, Kejun Li, Simin Lin, Wenjun Xiong et al. · 2022 · Research Square
  30. Physalis alkekengi var. franchetii extracts exert anti-tumour effects on non-small cell lung cancer and multiple myeloma by inhibiting STAT3 signalli
    Yu‐Fei Fu, Fanfan Zhu, Zhongjun Ma, Bin Lv, Xi Wang, Chunyan Dai, Xiaoqiong Ma, Pei Liu, Hang Lv, Xin Chen et al. · 2020
  31. The prognostic value of gene alterations in colon cancer patients: An analysis of the cBioPortal database
    Abdulraof Alqrache, Jonathon Hull · 2022 · Research Square
  32. Structural insights and computational molecular docking to explore novel therapeutic drug targets of STAT3
    2023 · Biomedical Letters
  33. Tocilizumab improves the efficacy of anti-PD-1 in a patient with advanced gastroesophageal junction cancer: a case report
    Yushi Cai, Xuan Shun Jin, Yun Dai · 2025 · Frontiers in Oncology
  34. Oncogene functions in human cancer
    Tang, Jianzhong · 2010 · ResearchSpace (University of Auckland)
  35. Discovery of SD-965 as a Potent, Selective, and Efficacious STAT3 PROTAC Degrader
    Dimin Wu, Haibin Zhou, Longchuan Bai, Ranjan Kumar Acharyya, Hoda Metwally, Donna McEachern, Mi Wang, Jelena Tošović, Rohan Kalyan Rej, Meilin Wang et al. · 2026 · Journal of Medicinal Chemistry
  36. Etude des interactions d'acides nucléiques avec des biomacromolécules et des nanoparticules : application à la vectorisation
    Frédéric Geinguenaud · 2015 · theses.fr (ABES)
  37. PTPRT/D MUTATION OR PROMOTER METHYLATION: IMPLICATIONS FOR STAT3 INHIBITION
    Noah D. Peyser · 2015 · D-Scholarship@Pitt (University of Pittsburgh)
  38. An Investigation into the Colorectal Cancer Chemopreventive Mechanisms of 3’, 4’, 5’, 5, 7-Pentamethoxyflavone (PMF)
    Isabel Lim Fong · 2012 · Unimas Institutional Repository (Universiti Malaysia Sarawak)