Antiradical Activities of Rambutan Peel: Study from Two Cultivars
Open accessAbstract
Background: Rambutan is tropical fruit consumed either in fresh or processed fruit.The direct consumption or processing of rambutan fruit resulted in high amount of waste from peel and seed, therefore, it is necessary to take benefit from rambutan peel to be used as food supplement via antioxidant properties.Objective: This study is intended to evaluate the antiradical activities of methanolic extract and its fraction of rambutan peel from two cultivars (Aceh and Binjai) and to correlate the antiradical activities with phenolics and flavonoid contents.Methodology: The rambutan peel from two cultivar (Aceh and Binjai) is dried, macerated with methanol, evaporated and added with water.The methanolic extract is fractionated with petroleum ether, chloroform and ethyl acetate to get the corresponding fraction.Methanolic extract and its fraction are then subjected to antiradical activity measurement using synthetic DPPH (2, 2-diphenyl-1-picrylhydrazyl) radical, phenolics determination and flavonoid determination.Results: The methanolic extract and its fraction,either cultivar Aceh or Binjai,revealed the high antiradical activities with similar.Ethyl acetate fraction exhibited the strongest antiradical activities among samples evaluated with IC 50 values of 2.66 µg mLG 1 (cultivar Aceh) and 2.62 µg mLG 1 (cultivar Binjai).Ethyl acetate fraction also exhibited the strongest phenolics and flavonoid contents accounting of 37.72±4.52g Gallic Acid Equivalent (GAE)/100 (Aceh) and 32.40±2.37g GAE/100 g (Binjai).The correlation between antiradical activities with phenolics and flavonoids contents showed with correlation, each with R 2 value of 0.0271 (phenolics) and 0.1122 (flavonoids).Conclusion: The methanolic extract and its fraction of rambutan peel cultivar Aceh and Binjai revealed strong DPPH antiradical activities therefore, rambutan peel can be exploited as natural antioxidant sources and is potential to be used as functional food.
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These findings are in agreement with studies that have shown that flavonoids and phenolic compounds are major contributors to the antioxidant activities of plant extracts.
“These findings are in agreement with those of studies that have shown that flavonoids and phenolic compounds are major contributors to the antioxidant activities of plant extracts (Rohman et al., 2017 [65]).”
From Comparative Analysis of Infusions and Ethanolic Extracts of Annona muricata Leaves from Colima, Mexico: Phytochemical Profile and Antioxidant Activity (2024) · cites this paper as Rohman et al., 2017 [65]
The Results and Discussion says phenolics and flavonoids are generally known to have antioxidant activity, but the paper's own analysis finds they did not contribute significantly to radical scavenging in the rambutan peel extracts studied. It reports weak correlations, with phenolic and flavonoid contents accounting for only 2.71% and 11.22% of the variation, respectively—not a major contribution. (LLM, conf=0.88)
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- Authors
- Rohman, A., Riyanto, S., ., M., ., S., & Endro Nugr, A.
- Affiliations
- Universitas Gadjah Mada (ID)
- Venue
- Research Journal of Phytochemistry
- Publisher
- Science Alert
- Published
- 2016-12-15
- Volume
- 11
- Issue
- 1
- Pages
- 42-47
- ISSN
- 1819-3471 (ISSN-L)
- OpenAlex
- W2561172886
- Cited by
- 27
- References
- 19
- Citations by year
- 2024: 2 · 2023: 3 · 2022: 10 · 2021: 5 · 2020: 2 · 2019: 1 · 2018: 1 · 2017: 3
- FWCI
- 1.31
- Type
- journal article
- Language
- en
- Open access
- diamond
- doi.org
- Locations
- Research Journal of Phytochemistry (publishedVersion)
- Funders
- Universitas Gadjah Mada
- Topics
- Health Sciences › Medicine › Biochemistry (medical) › Phytochemicals and Antioxidant Activities
- Health Sciences › Nursing › Nutrition and Dietetics › Pomegranate: compositions and health benefits
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Medicinal Plant Research
- Keywords
- rambutan peel, Nephelium lappaceum, free radical scavenging, antioxidant activity, DPPH radical scavenging, methanol extract, ethyl acetate fraction, phenolic content, flavonoid content, fruit waste valorization, functional foods
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