The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Role of uric acid in hypertension, renal disease, and metabolic syndrome.
Abstract
Hyperuricemia has long been known to be associated with cardiovascular disease, and it is particularly common in people with hypertension, metabolic syndrome, or kidney disease. Most authorities have viewed elevated uric acid as a secondary phenomenon that is either innocuous or perhaps even beneficial, since uric acid can be an antioxidant. However, recent experiments have challenged this viewpoint. In this paper we argue that uric acid is a true risk factor for cardiovascular disease. Furthermore, we suggest that the recent increased intake in the American diet of fructose, which is a known cause of hyperuricemia, may be contributing to the current epidemic of obesity and diabetes.
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Citations
Cites
Schulze, M. B. (2004) · JAMA · doi:10.1001/jama.292.8.927 · Cited by 1,639
Xanthine Oxidase Inhibition Reverses Endothelial Dysfunction in Heavy Smokers
Guthikonda, S., Sinkey, C., Barenz, T., & Haynes, W. G. (2003) · Circulation · doi:10.1161/01.cir.0000046448.26751.58 · Cited by 225
Cited by
Uric acid, hyperuricemia and vascular diseases
Jin, M. (2012) · Frontiers in Bioscience · doi:10.2741/3950 · Cited by 406
Teff, K. L., Grudziak, J., Townsend, R. R., Dunn, T. N., Grant, R. W., Adams, S. H., Keim, N. L., Cummings, B. P., Stanhope, K. L., & Havel, P. J. (2009) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2008-2192 · Cited by 301
Plasma uric acid and the risk of type 2 diabetes in a Chinese community
Chien, K.-L., Chen, M.-F., Hsu, H.-C., Chang, W.-T., Su, T.-C., Lee, Y.-T., & Hu, F. B. (2008) · Clinical Chemistry · doi:10.1373/clinchem.2007.095190 · Cited by 172
Epidemiology of hypertensive disorders in pregnancy
Stuart, J. J., Gray, K. J., Rich-Edwards, J. W., & Roberts, J. M. (2022) · Chesley's Hypertensive Disorders in Pregnancy · doi:10.1016/b978-0-12-818417-2.00023-3 · Cited by 11
Metadata
- Authors
- Heinig, M., & Johnson, R. J.
- Venue
- Cleveland Clinic Journal of Medicine
- Publisher
- Cleveland Clinic Journal of Medicine
- Published
- 2006-12-01
- Volume
- 73
- Issue
- 12
- Pages
- 1059-1064
- ISSN
- 0891-1150 (ISSN-L)
- 1939-2869
- OpenAlex
- W2093892811
- Cited by
- 291
- References
- 2
- FWCI
- 6.09
- Type
- journal article
- Language
- en
- Open access
- closed
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- Heinig, M., & Johnson, R. J. (2006). Role of uric acid in hypertension, renal disease, and metabolic syndrome. Cleveland Clinic Journal of Medicine. https://doi.org/10.3949/ccjm.73.12.1059
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
