Flagellin as an Adjuvant: Cellular Mechanisms and Potential

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Items 301–399 of 399

1. HA1-2-fljB Vaccine Induces Immune Responses against Pandemic Swine-Origin H1N1 Influenza Virus in Mice
   Xilong Kang, Yun Yang, Yang Jiao, Hongqin Song, Li Song, Dan Xiong, Li Juan Wu, Zhiming Pan, Xinan Jiao · 2016 · Microbial Physiology
2. Enhancement of antigen-specific humoral immune responses and protein solubility through conjugation of bacterial flagellin, Vibrio vulnificus FlaB, to the N-terminus of porcine epidemic diarrhea virus surface protein antigen S0
   Seo-ho Oh, Young-Saeng K. Cho, Ho-Bin Lee, Sang‐Mok Lee, Whee-Soo Kim, Hong Liang, Chong-Su Cho, Yun-Jaie Choi, Sang‐Kee Kang · 2019 · Journal of Veterinary Science
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4. Adjuvants for Skin Vaccination
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5. Developments in adjuvants for fish vaccines
   Jarl Bøgwald, Roy A. Dalmo · 2012 · Elsevier eBooks
6. Inducible secreting TLR5 agonist CBLB502 enhances antitumor activity of CAR133-NK92 cells for colorectal cancer
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7. FliC adjuvant augments protective efficacy of recombinant T2544 antigen against Salmonella Typhiand Paratyphi A by increasing serum antibodies, intestinal secretory immunoglobulin A and T cell memory
   Suparna Chakraborty, Pujarini Dutta, Ananda Pal, Swarnali Chakraborty, Sneha Mitra, Shin‐ichi Miyoshi, Santasabuj Das · 2025 · Vaccine
8. Inserting Omp22 into the flagellin protein, replacing its hypervariable region, results in stronger protection against lethal Acinetobacter baumannii infection
   Bahador Behrouz, Iraj Rasooli, Farzad Badmasti · 2024 · Scientific Reports
9. Computational identification of membrane proteins for vaccine design against drug-resistant Moraxella catarrhalis
   Fizza Arshad, Rania Pervaiz, Asifa Sarfraz, Hasan Ejaz, Amal Alotaibi, Riaz Ullah, Umar Nishan, Abid Ali, Muhammad Umer Khan, Mohibullah Shah · 2025 · Molecular Genetics and Genomics
10. The Cholera Toxin B Subunit (CTB) Fused to the Porcine Arterivirus Matrix M and GP5 Envelope Proteins Fails to Enhance the GP5-Specific Antibody Response in Pigs Immunized with Adenovectors
    Élodie Roques, Martin Lessard, Denis Archambault · 2015 · Molecular Biotechnology
11. Immunogenicity in African Green Monkeys of M Protein Mutant Vesicular Stomatitis Virus Vectors and Contribution of Vector-Encoded Flagellin
    Marlena M. Westcott, Jason R. Smedberg, Matthew J. Jorgensen, Shelby H. Puckett, Douglas S. Lyles · 2018 · Vaccines
12. Comment on “Type 1 Diabetes in BioBreeding Rats Is Critically Linked to an Imbalance between Th17 and Regulatory T Cells and an Altered TCR Repertoire”
    Jan‐Luuk Hillebrands, Jan Rozing, Jeroen T. J. Visser · 2011 · The Journal of Immunology
13. Vibrio parahaemolyticus flagellin F (FlaF) induces the inflammatory response of the Tetraodon nigroviridis through the TLR5M
    Xue Li Yu, Jiachang Xu, Songze Gao, Yulin Zhao, Yuyou Lu, Niuniu Deng, Haoran Lin, Yong Zhang, Danqi Lu · 2022 · Aquaculture
14. The Role of Inflammasomes in Adjuvant-Driven Humoral and Cellular Immune Responses
    Natalia Muñoz‐Wolf, S. Mccluskey, E. Lavelle · 2017 · Elsevier eBooks
15. F18+ Escherichia coli flagellin expression in Salmonella has immunoadjuvant effects in a ghost vaccine candidate containing E. coli Stx2eB, FedF and FedA against porcine edema disease
    Gayeon Won, John Hwa Lee · 2018 · Comparative Immunology Microbiology and Infectious Diseases
16. Harnessing flagellin of Ligilactobacillus agilis as a surface display scaffold for an HIV-1 epitope
    Shunya Suzuki, Gregg A. Dean, Akinobu Kajikawa · 2025 · Applied and Environmental Microbiology
17. Intranasal Vaccine Adjuvants and Delivery Platforms: From Barrier Mechanisms to Clinical Translation
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18. Activation of NLRC4 downregulates TLR5-mediated antibody immune responses against flagellin
    Wei Li, Jingyi Yang, Ejuan Zhang, Maohua Zhong, Yang Xiao, Jie Yu, Dihan Zhou, Yuan Cao, Yi Yang, Yaoming Li et al. · 2015 · Cellular and Molecular Immunology
19. Immunization with recombinant HPV16-E7d in fusion with Flagellin as a cancer vaccine: Effect of antigen-adjuvant orientation on the immune response pattern
    Meysam Gachpazan, Ali Ahmadnia Alashti, Hamid Reza Jahantigh, Majid Moghbeli, Sobhan Faezi, Seyed Younes Hosseini, Mohammad Mahdi Eftekharian, Maryam Nasimi, Farhad Motavalli Khiavi, Alireza Rahimi et al. · 2025 · Immunologic Research
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    Mani Divya, Sundaram Rajakumar, Pudukadu Munusamy Ayyasamy · 2025 · British Poultry Science
21. Development of a novel nanobody-fused flagellin adjuvant to enhance immunogenicity in a PCV2 subunit vaccine
    C Wang, Tianqi Xu, Jinliang Wang, Li Feng, Yu Guan, Dong Lin, Yan Wang, Weiqin Meng, Fengrong Tian, Feng Wei · 2025 · Microbial Pathogenesis
22. Adjuvant Mucosal Strategies Confer Safe and Effective Immunity Against Mycoplasma pneumoniae and Overcome Vaccine-Associated Enhanced Lung Pathology
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23. Salmonella flagellin acted as an effective fusion partner for expression of Plasmodium falciparum surface protein 25 in Escherichia coli
    Feng Qian, Mengmeng Li, Yong Chen, Lin Jiang, Huji Xu · 2016 · Human Vaccines & Immunotherapeutics
24. Synthesis of a conjugate of 3´-sialyllactoside with recombinant flagellin as a carrier protein and assessment of its immunological activity in comparison with that of a similar hemocyanin-based conjugate
    E. M. Novikova, Elena A. Khatuntseva, Yury E. Tsvetkov, N.A. Razvalyayeva, D. A. Goncharuk, O. A. Zeynalov, Nikolay E. Nifantiev, Степаненко Родион Николаевич · 2015 · Russian Chemical Bulletin
25. EVALUATION OF LACTOBACILLUS PROBIOTICS AS ADJUVANTS FOR NASAL IMMUNIZATION WITH CHIMERIC PNEUMOCOCCAL VACCINE
    Galina Leontieva, Tatiana A. Kramskaya, K. B. Grabovskaya, Viktoria Filimonova, Jonathan Laiño, Julio Villena, S. Alvares, В. Н. Даниленко, Alexander N. Suvorov · 2016 · Medical Immunology (Russia)
26. Purification of Native Flagellin
    María José González, Victoria Iribarnegaray, Pablo Zunino, Paola Scavone · 2019 · Methods in molecular biology
27. The Integrity of α-β-α Sandwich Conformation Is Essential for a Novel Adjuvant TFPR1 to Maintain Its Adjuvanticity
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28. Molecular Detection of Virulence Factor of Campylobacter Jejuni Isolated from Organs of Chickens, Ducks, and Pigeons from Different Egyptian Provinces
    Azhar G. Shalaby, Heba Abdel Aziz, Mai M. Morsy · 2024 · Egyptian Journal of Veterinary Science
29. Dual Immunization with Lipoprotein Tp0663 and Flagellin FlaB3 Offers Augmented Protection against Treponema pallidum in Mice
    Yafeng Xie, Yiming Zhou, Jing Yang, Man Xu · 2025 · ACS Omega
30. In-silico core proteome analysis for chimeric vaccine development against tick-borne tularemia
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31. Optimized flagellin enhances systemic and mucosal immune responses induced by SARS-CoV-2 virus-like particle vaccines
    Li Song, Guoyu He, Yaodan Cui, Ruimeng Tan, Yue (April) Wang, Hui Zhang, 钱汶, Shizhong Geng, Z C Pan, Xinan Jiao · 2026 · Vaccine
32. Antigen Delivery Systems as Oral Adjuvants
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38. Mutagenesis to Orient Conjugation and Preserve Self‐adjuvant Properties of Flagellin in Conjugates
    Laura Laneque, Annie Lambert, Delphine Cayet, Caroline Gilleron, Emmanuelle Courtois, Chloé Cloteau, Cédric Broussard, Bastien Annic, Thomas Bessonnet, Emilie Camberlein et al. · 2025 · ChemBioChem
39. Induction of immune response in broiler chickens immunized with recombinant FliC and challenged by Salmonella Typhimurium
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41. Novos adjuvantes vacinais: importante ferramenta para imunoterapia da leishmaniose visceral
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42. Recombinant Flagellin and Incomplete Freund’s Adjuvant Potentiate the Vaccine Efficacy of the Iron Acquisition Protein (HitA) of Pseudomonas aeruginosa
    Mona A. Elhosary, Nadia El Guink, Amany Abdel-Bary, Hamida Moustafa Abou-Shleib, Mohammed Bahey-El-Din · 2020 · Journal of Advanced Pharmacy Research
43. Response to Comment on “Flagellin Induces Antibody Responses through a TLR5- and Inflammasome-Independent Pathway”
    Américo Harry López-Yglesias, Chun–Chi Lu, Kelly D. Smith · 2014 · The Journal of Immunology
44. Bacterial flagellin- a novel adjuvant for vaccine strategies
    Natasha Hynes · 2011 · NORA - Norwegian Open Research Archives
45. The role of microbial translocation and gut microbiota in HIV-1 infection
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46. Flagellin synergistically enhances anti-tumor effect of EGFRvIII peptide in a glioblastoma-bearing mouse brain tumor model
    Jin Myung Choi, Sa-Hoe Lim, Zhipeng Liu, Joon Haeng Rhee, Mee Sun Yoon, Jung‐Joon Min, Shin Jung · 2021 · Research Square
47. Caracterização dos efeitos imunomoduladores e adjuvanticidade da flagelina Hag de Bacillus subtilis.
    Carolina Salcedo Rivillas · 2012
48. Geração e análise da imunogenicidade de proteínas recombinantes baseadas nas diferentes formas do antígeno circumsporozoíta de Plasmodium vivax visando o desenvolvimento de uma vacina universal contra malária.
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49. Roles in innate immune receptors: Host : pathogen interactions and strengthening vaccines
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51. Avaliação terapêutica da formulação vacinal baseada no peptídeo P10 derivado da glicoproteína (gp43) de Paracoccidioides brasiliensis e na flagelina de Salmonella (FliCd).
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52. Commentary: Incorporation of membrane-anchored flagellin or Escherichia coli heat-labile enterotoxin B subunit enhances the immunogenicity of rabies virus-like particles in mice and dogs
    Arun Kumar · 2015 · Frontiers in Microbiology
53. Pattern recognition receptors: sentinels in innate immunity and targets of new vaccine
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54. Cloning and expression of the Vibrio cholera recombinant FlaA Flagellin protein and evaluation of its antigenicity characteristics
    Hamid Kazemian, Mohammad Najafimosleh, Hamid Abtahi · 2012
55. Structural characterization of antibodies against lipopolysaccharide antigens: Insights into primary antibody response
    Omid Haji‐Ghassemi · 2015 · UVic’s Research and Learning Repository (University of Victoria)
56. Innate Immune Recognition of Conserved Structural Features of Bacterial Flagellin Shapes Host Antibody Responses
    Américo Harry López-Yglesias · 2014 · ResearchWorks at the University of Washington (University of Washington)
57. Rainfall Variability and its Impact on Reported OPD Cases of Salmonella typhi Infections in Sunyani, Ghana
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58. Adjuvants for Substance Abuse Vaccines
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60. Immunogenicity and Safety of Lactobacilli as Oral Mucosal Vaccine Vectors.
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63. The role of the Toll-like receptors in systemic inflammatory response to cardiac surgery
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64. Development & Expression Of A Novel Synthetic Flagellin Fusion Protein Containing A Shigella Toxoid Subunit As A Potential Vaccine Against Shigellosis & Stec
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65. Candidate vaccine construction against tick-born encephalitis based on hybrid recombinant flagG-protE-protein
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