The DOI matches its Crossref record.
Cytotoxic Properties of the Eosinophil Major Basic Protein
Abstract
Summary: The eosinophil major basic protein (MBP) damages cells including those from organs whose dysfunction is associated with eosinophil infiltration. Concentrations of MBP in the toxic range were found in sputa from asthmatics, in pleural fluid and in sera. These findings suggest the hypothesis that the eosinophil produces damage to cells in disease.
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Citations
Cited by
Asthma: From Bronchoconstriction to Airways Inflammation and Remodeling
BOUSQUET, J., JEFFERY, P. K., BUSSE, W. W., JOHNSON, M., & VIGNOLA, A. M. (2000) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.161.5.9903102 · Cited by 1,702
Rothenberg, M. E., & Hogan, S. P. (2006) · Annual Review of Immunology · doi:10.1146/annurev.immunol.24.021605.090720 · Cited by 1,356
Expression of mRNA for interleukin-5 in mucosal bronchial biopsies from asthma.
Hamid, Q., Azzawi, M., Ying, S., Moqbel, R., Wardlaw, A. J., Corrigan, C. J., Bradley, B., Durham, S. R., Collins, J. V., & Jeffery, P. K. (1991) · Journal of Clinical Investigation · doi:10.1172/jci115166 · Cited by 833
FAUCI, A. S., HARLEY, J. B., ROBERTS, W. C., FERRANS, V. J., GRALNICK, H. R., & BJORNSON, B. H. (1982) · Annals of Internal Medicine · doi:10.7326/0003-4819-97-1-78 · Cited by 823
Leiferman, K. M., Ackerman, S. J., Sampson, H. A., Haugen, H. S., Venencie, P. Y., & Gleich, G. J. (1985) · New England Journal of Medicine · doi:10.1056/nejm198508013130502 · Cited by 408
Self-citation
Metadata
- Authors
- Gleich, G. J., Frigas, E., Loegering, D. A., Wassom, D. L., & Steinmuller, D.
- Venue
- The Journal of Immunology
- Publisher
- Oxford University Press (OUP)
- Published
- 1979-12-01
- Volume
- 123
- Issue
- 6
- Pages
- 2925-2927
- ISSN
- 0022-1767 (ISSN-L)
- 1550-6606
- OpenAlex
- W1606940682
- Cited by
- 596
- References
- 0
- FWCI
- 11.36
- Type
- journal article
- Language
- en
- Open access
- closed
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- The paper
- Gleich, G. J., Frigas, E., Loegering, D. A., Wassom, D. L., & Steinmuller, D. (1979). Cytotoxic Properties of the Eosinophil Major Basic Protein. The Journal of Immunology. https://doi.org/10.4049/jimmunol.123.6.2925
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
