Overexpression of Soluble Fas Ligand following Adeno-Associated Virus Gene Therapy Prevents Retinal Ganglion Cell Death in Chronic and Acute Murine Models of Glaucoma

The Ocular Hypertension Treatment Study

Kass, M. A. (2002) · Archives of Ophthalmology · doi:10.1001/archopht.120.6.701 · Cited by 3,715 · see citing works

Reduction of Intraocular Pressure and Glaucoma Progression

Heijl, A. (2002) · Archives of Ophthalmology · doi:10.1001/archopht.120.10.1268 · Cited by 3,407 · see citing works

Molecular cloning and expression of the fas ligand, a novel member of the tumor necrosis factor family

Suda, T., Takahashi, T., Golstein, P., & Nagata, S. (1993) · Cell · doi:10.1016/0092-8674(93)90326-l · Cited by 2,488 · see citing works

Fas Ligand-Induced Apoptosis as a Mechanism of Immune Privilege

Griffith, T. S., Brunner, T., Fletcher, S. M., Green, D. R., & Ferguson, T. A. (1995) · Science · doi:10.1126/science.270.5239.1189 · Cited by 1,990 · see citing works

Müller cells in the healthy and diseased retina

Bringmann, A., Pannicke, T., Grosche, J., Francke, M., Wiedemann, P., Skatchkov, S. N., Osborne, N. N., & Reichenbach, A. (2006) · Progress in Retinal and Eye Research · doi:10.1016/j.preteyeres.2006.05.003 · Cited by 1,905 · see citing works

Autocrine T-cell suicide mediated by APO-1/(Fas/CD95)

Dhein, J., Walczak, H., Bäumler, C., Debatin, K., & Krammer, P. (1995) · Nature · doi:10.1038/373438a0 · Cited by 1,814 · see citing works

Fas(CD95)/FasL interactions required for programmed cell death after T-cell activation

Ju, S., Panka, D., Cui, H., Ettinger, R., EI-Khatib, M., Sherr, D., Stanger, B., & Marshak-Rothstein, A. (1995) · Nature · doi:10.1038/373444a0 · Cited by 1,709 · see citing works

Cell-autonomous Fas (CD95)/Fas-ligand interaction mediates activation-induced apoptosis in T-cell hybridomas

Brunner, T., Mogil, R. J., LaFace, D., Yoo, N. J., Mahboubi, A., Echeverri, F., Martin, S. J., Force, W. R., Lynch, D. H., Ware, C. F., et al. (1995) · Nature · doi:10.1038/373441a0 · Cited by 1,314 · see citing works

The Framingham Eye Study monograph: An ophthalmological and epidemiological study of cataract, glaucoma, diabetic retinopathy, macular degeneration, and visual acuity in a general population of 2631 adults, 1973-1975.

Leibowitz, H. M., Krueger, D. E., Maunder, L. R., Milton, R. C., KINI, M. M., Kahn, H. A., Nickerson, R. J., Pool, J., Colton, T., Ganley, J. P., et al. (1980) · PubMed · Cited by 1,250 · see citing works

Astrocyte glutamate transport: Review of properties, regulation, and physiological functions

Anderson, C. M., & Swanson, R. A. (2000) · Glia · doi:10.1002/1098-1136(200010)32:1 · Cited by 1,218 · see citing works

Relationship Between Intraocular Pressure and Primary Open Angle Glaucoma Among White and Black Americans

Sommer, A. H. (1991) · Archives of Ophthalmology · doi:10.1001/archopht.1991.01080080050026 · Cited by 1,182 · see citing works

The molecular basis of retinal ganglion cell death in glaucoma

Almasieh, M., Wilson, A. M., Morquette, B., Vargas, J. L. C., & Polo, A. D. (2011) · Progress in Retinal and Eye Research · doi:10.1016/j.preteyeres.2011.11.002 · Cited by 974 · see citing works

Retinal ganglion cell death in experimental glaucoma and after axotomy occurs by apoptosis.

Quigley, H. A., Nickells, R. W., Kerrigan, L. A., Pease, M. E., Thibault, D., & Zack, D. J. (1995) · PubMed · Cited by 932 · see citing works

Downregulation of Fas ligand by shedding

Tanaka, M., Itai, T., Adachi, M., & Nagata, S. (1998) · Nature Medicine · doi:10.1038/nm0198-031 · Cited by 666 · see citing works

Axons of retinal ganglion cells are insulted in the optic nerve early in DBA/2J glaucoma

Howell, G. R., Libby, R. T., Jakobs, T., Smith, R. S., Phalan, F. C., Barter, J. W., Barbay, J. M., Marchant, J. K., Nagaraju, M., Porciatti, V., et al. (2007) · The Journal of Cell Biology · doi:10.1083/jcb.200706181 · Cited by 593 · see citing works

Membrane Fas Ligand Kills Human Peripheral Blood T Lymphocytes, and Soluble Fas Ligand Blocks the Killing

Suda, T., Hashimoto, H., Tanaka, M., Ochi, T., & Nagata, S. (1997) · Journal of Experimental Medicine · doi:10.1084/jem.186.12.2045 · Cited by 558 · see citing works

Essential iris atrophy, pigment dispersion, and glaucoma in DBA/2J mice.

John, S. W. M., Smith, R. S., Savinova, O. V., Hawes, N. L., Chang, B., Turnbull, D., Davisson, M. T., Roderick, T. H., & Heckenlively, J. R. (1998) · PubMed · Cited by 549 · see citing works

New Genes Tied to Endocrine, Metabolic, and Dietary Regulation of Lifespan from a Caenorhabditis elegans Genomic RNAi Screen

Hansen, M., Hsu, A., Dillin, A. G., & Kenyon, C. J. (2005) · PLoS Genetics · doi:10.1371/journal.pgen.0010017 · Cited by 533 · see citing works

Definition of glaucoma: clinical and experimental concepts

Casson, R. J., Chidlow, G., Wood, J. P. M., Crowston, J. G., & Goldberg, I. (2012) · Clinical and Experimental Ophthalmology · doi:10.1111/j.1442-9071.2012.02773.x · Cited by 510 · see citing works

Molecular clustering identifies complement and endothelin induction as early events in a mouse model of glaucoma

Howell, G. R., Macalinao, D. G., Sousa, G. L., Walden, M., Soto, I., Kneeland, S. C., Barbay, J. M., King, B. L., Marchant, J. K., Hibbs, M., et al. (2011) · Journal of Clinical Investigation · doi:10.1172/jci44646 · Cited by 473 · see citing works

TUNEL-Positive Ganglion Cells in Human Primary Open-angle Glaucoma

Kerrigan, L. A. (1997) · Archives of Ophthalmology · doi:10.1001/archopht.1997.01100160201010 · Cited by 464 · see citing works

Tumor Necrosis Factor-α Mediates Oligodendrocyte Death and Delayed Retinal Ganglion Cell Loss in a Mouse Model of Glaucoma

Nakazawa, T., Nakazawa, C., Matsubara, A., Noda, K., Hisatomi, T., She, H., Michaud, N. A., Hafezi‐Moghadam, A., Miller, J. W., & Benowitz, L. I. (2006) · Journal of Neuroscience · doi:10.1523/jneurosci.2801-06.2006 · Cited by 432 · see citing works

The metalloproteinase matrilysin proteolytically generates active soluble Fas ligand and potentiates epithelial cell apoptosis

Powell, W. C., Fingleton, B., Wilson, C. L., Boothby, M. R., & Matrisian, L. M. (1999) · Current Biology · doi:10.1016/s0960-9822(00)80113-x · Cited by 424 · see citing works

CD95 ligand (FasL)-induced apoptosis is necessary for corneal allograft survival.

Stuart, P. M., Griffith, T. S., Usui, N., Pepose, J., Yu, X.-H., & Ferguson, T. (1997) · Journal of Clinical Investigation · doi:10.1172/jci119173 · Cited by 406 · see citing works

TNF-alpha and TNF-alpha receptor-1 in the retina of normal and glaucomatous eyes.

Tezel, G., Li, L. Y., Patil, R. V., & Wax, M. B. (2001) · PubMed · Cited by 398 · see citing works

Susceptibility to Neurodegeneration in a Glaucoma Is Modified by Bax Gene Dosage

Libby, R. T., Li, Y., Savinova, O. V., Barter, J. W., Smith, R. S., Nickells, R. W., & John, S. W. M. (2005) · PLoS Genetics · doi:10.1371/journal.pgen.0010004 · Cited by 358 · see citing works

Activated microglia in the human glaucomatous optic nerve head

Yuan, L., & Neufeld, A. H. (2001) · Journal of Neuroscience Research · doi:10.1002/jnr.1104 · Cited by 348 · see citing works

Cutting Edge: FAS (CD95) Mediates Noncanonical IL-1β and IL-18 Maturation via Caspase-8 in an RIP3-Independent Manner

Bossaller, L., Chiang, P.-I., Schmidt‐Lauber, C., Ganesan, S., Kaiser, W. J., Rathinam, V. A. K., Mocarski, E. S., Subramanian, D., Green, D. R., Silverman, N. S., et al. (2012) · The Journal of Immunology · doi:10.4049/jimmunol.1202121 · Cited by 287 · see citing works

Transcriptional Control of the TNF Gene

Falvo, J. V., Tsytsykova, A. V., & Goldfeld, A. E. (2010) · Current directions in autoimmunity · doi:10.1159/000289196 · Cited by 284 · see citing works

Fas ligand/Fas system in the brain: regulator of immune and apoptotic responses

Choi, C., & Benveniste, E. N. (2004) · Brain Research Reviews · doi:10.1016/j.brainresrev.2003.08.007 · Cited by 270 · see citing works

Opposing Effects of Transmembrane and Soluble FAS Ligand Expression on Inflammation and Tumor Cell Survival

Hohlbaum, A. M., Moe, S., & Marshak‐Rothstein, A. (2000) · The Journal of Experimental Medicine · doi:10.1084/jem.191.7.1209 · Cited by 241 · see citing works

Radiation treatment inhibits monocyte entry into the optic nerve head and prevents neuronal damage in a mouse model of glaucoma

Howell, G. R., Soto, I., Zhu, X., Ryan, M. M., Macalinao, D. G., Sousa, G. L., Caddle, L. B., MacNicoll, K. H., Barbay, J. M., Porciatti, V., et al. (2012) · Journal of Clinical Investigation · doi:10.1172/jci61135 · Cited by 233 · see citing works

Effect of CNTF on retinal ganglion cell survival in experimental glaucoma

Pease, M. E., Zack, D. J., Berlinicke, C., Bloom, K., Cone, F., Wang, Y., Klein, R. L., Hauswirth, W. W., & Quigley, H. A. (2009) · Investigative Opthalmology & Visual Science · doi:10.1167/iovs.08-3013 · Cited by 222 · see citing works

Etanercept, a Widely Used Inhibitor of Tumor Necrosis Factor-α (TNF- α), Prevents Retinal Ganglion Cell Loss in a Rat Model of Glaucoma

Roh, M., Zhang, Y., Murakami, Y., Thanos, A., Lee, S. C., Vavvas, D. G., Benowitz, L. I., & Miller, J. W. (2012) · PLoS ONE · doi:10.1371/journal.pone.0040065 · Cited by 220 · see citing works

Proteomic Identification of Oxidatively Modified Retinal Proteins in a Chronic Pressure-Induced Rat Model of Glaucoma

Tezel, G. ̈. ̈., Yang, X., & Cai, J. (2005) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.05-0208 · Cited by 209 · see citing works

Non-apoptotic Fas signaling

Wajant, H., Pfizenmaier, K., & Scheurich, P. (2002) · Cytokine & Growth Factor Reviews · doi:10.1016/s1359-6101(02)00072-2 · Cited by 192 · see citing works

An immunohistochemical study of neuronal and glial cell reactions in retinae of rats with experimental glaucoma

Wang, X., Tay, S. S., & Ng, Y. (2000) · Experimental Brain Research · doi:10.1007/s002210000360 · Cited by 191 · see citing works

Optic Neuropathy Due to Microbead-Induced Elevated Intraocular Pressure in the Mouse

Chen, H., Wei, X., Cho, K., Chen, G., Sappington, R. M., Calkins, D. J., & Chen, D. F. (2010) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.09-5115 · Cited by 184 · see citing works

Neurodegenerative and Inflammatory Pathway Components Linked to TNF-α/TNFR1 Signaling in the Glaucomatous Human Retina

Yang, X., Luo, C., Cai, J., Powell, D. W., Yu, D., Kuehn, M. H., & Tezel, G. (2011) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.11-8152 · Cited by 183 · see citing works

Involvement of APO2 ligand/TRAIL in activation-induced death of Jurkat and human peripheral blood T cells

Martínez‐Lorenzo, M. J., Álava, M. A., Gamen, S., Kim, K. J., Chuntharapai, A., Piñeiro, A., Naval, J., & Anel, A. (1998) · European Journal of Immunology · doi:10.1002/(sici)1521-4141(199809)28:09 · Cited by 182 · see citing works

A Sick Eye in a Sick Body? Systemic Findings in Patients with Primary Open-angle Glaucoma

Pache, M., & Flammer, J. (2006) · Survey of Ophthalmology · doi:10.1016/j.survophthal.2006.02.008 · Cited by 172 · see citing works

Changes in Gene Expression in Experimental Glaucoma and Optic Nerve Transection: The Equilibrium between Protective and Detrimental Mechanisms

Yang, Z., Quigley, H. A., Pease, M. E., Yang, Y., Jiang, Q., Valenta, D. F., & Zack, D. J. (2007) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.07-0542 · Cited by 169 · see citing works

The Role of Glia, Mitochondria, and the Immune System in Glaucoma

Tezel, G. (2009) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.08-2717 · Cited by 164 · see citing works

Baculoviral IAP Repeat-Containing-4 Protects Optic Nerve Axons in a Rat Glaucoma Model

McKinnon, S. J., Lehman, D. M., Tahzib, N. G., Ransom, N. L., Reitsamer, H. A., Liston, P., LaCasse, E. C., Li, Q., Korneluk, R. G., & Hauswirth, W. W. (2002) · Molecular Therapy · doi:10.1006/mthe.2002.0608 · Cited by 163 · see citing works

Persistent transgene product in retina, optic nerve and brain after intraocular injection of rAAV

Dudus, L., Anand, V., Acland, G. M., Chen, S.-J., Wilson, J. M., Fisher, K. J., Maguire, A. M., & Bennett, J. (1999) · Vision Research · doi:10.1016/s0042-6989(98)00308-3 · Cited by 160 · see citing works

Neurodegeneration severity can be predicted from early microglia alterations monitoredin vivoin a mouse model of chronic glaucoma

Bosco, A., Romero, C. O., Breen, K., Chagovetz, A. A., Steele, M. R., Ambati, B. K., & Vetter, M. L. (2015) · Disease Models & Mechanisms · doi:10.1242/dmm.018788 · Cited by 158 · see citing works

Neurochemical Evidence to Implicate Elevated Glutamate in the Mechanisms of High Intraocular Pressure (IOP)-induced Retinal Ganglion Cell Death in Rat

Nucci, C., Tartaglione, R., Rombolà, L., Morrone, L. A., Fazzi, E. M., & Bagetta, G. (2005) · NeuroToxicology · doi:10.1016/j.neuro.2005.06.002 · Cited by 155 · see citing works

HLA MATCHING AND CORNEAL GRAFTING

Batchelor, J. R., Casey, T. A., Gibbs, D. C., Lloyd, D. F. A., Werb, A., Prasad, S., & James, A. R. (1976) · The Lancet · doi:10.1016/s0140-6736(76)90355-x · Cited by 153 · see citing works

CD95 (Fas/Apo-1) as a Receptor Governing Astrocyte Apoptotic or Inflammatory Responses: A Key Role in Brain Inflammation?

Saas, P., Boucraut, J., Quiquerez, A., Schnüriger, V., Perrin, G., Desplat‐Jégo, S., Bernard, D. J., Walker, P. R., & Dietrich, P. (1999) · The Journal of Immunology · doi:10.4049/jimmunol.162.4.2326 · Cited by 151 · see citing works

Fas and Fas ligand enhance the pathogenesis of experimental allergic encephalomyelitis, but are not essential for immune privilege in the central nervous system

Sabelko, K. A., Kelly, K. A., Nahm, M. H., Cross, A. H., & Russell, J. H. (1997) · The Journal of Immunology · doi:10.4049/jimmunol.159.7.3096 · Cited by 150 · see citing works

Fas Ligand Engagement of Resident Peritoneal Macrophages In Vivo Induces Apoptosis and the Production of Neutrophil Chemotactic Factors

Hohlbaum, A. M., Gregory, M. S., Ju, S., & Marshak‐Rothstein, A. (2001) · The Journal of Immunology · doi:10.4049/jimmunol.167.11.6217 · Cited by 148 · see citing works

Involvement of Inflammation, Degradation, and Apoptosis in a Mouse Model of Glaucoma

Zhou, X., Li, F., Kong, L., Tomita, H., Li, C. R., & Cao, W. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m502641200 · Cited by 143 · see citing works

Absence of glaucoma in DBA/2J mice homozygous for wild-type versions of Gpnmb and Tyrp1

Howell, G. R., Libby, R. T., Marchant, J. K., Wilson, L. A., Cosma, I. M., Smith, R. S., Anderson, M. G., & John, S. W. M. (2007) · BMC Genetics · doi:10.1186/1471-2156-8-45 · Cited by 133 · see citing works

Adeno-Associated Virus Gene Transfer to Mouse Retina

Ali, R. R., Reichel, M. B., de Alwis, M., Kanuga, N., Kinnon, C., Levinsky, R. J., Hunt, D. M., Bhattacharya, S. S., & Thrasher, A. J. (1998) · Human Gene Therapy · doi:10.1089/hum.1998.9.1-81 · Cited by 124 · see citing works

Regulation of TNF Expression by Multiple Mitogen-Activated Protein Kinase Pathways

Zhu, W. P., Downey, J. S., Gu, J., Padova, F. D., Gram, H., & Han, J. (2000) · The Journal of Immunology · doi:10.4049/jimmunol.164.12.6349 · Cited by 120 · see citing works

Fate of orthotopic corneal allografts in eyes that cannot support anterior chamber-associated immune deviation induction.

Sano, Y., Ksander, B. R., & Streilein, J. W. (1995) · PubMed · Cited by 110 · see citing works

The Pathogenesis of Glaucoma in the Interplay with the Immune System

Rieck, J. (2013) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.12-9781 · Cited by 104 · see citing works

Activation of the Extracellular Signal-Regulated Kinase 1/2 Pathway by AAV Gene Transfer Protects Retinal Ganglion Cells in Glaucoma

Zhou, Y., Pernet, V., Hauswirth, W. W., & Polo, A. D. (2005) · Molecular Therapy · doi:10.1016/j.ymthe.2005.04.004 · Cited by 103 · see citing works

Up-regulation of Glial Fibrillary Acidic Protein in the Retina of Primate Eyes With Experimental Glaucoma

Tanihara, H. (1997) · Archives of Ophthalmology · doi:10.1001/archopht.1997.01100150754011 · Cited by 102 · see citing works

Progression of Visual Acuity after Penetrating Keratoplasty

Price, F. W., Whitson, W. E., & Marks, R. G. (1991) · Ophthalmology · doi:10.1016/s0161-6420(91)32136-5 · Cited by 101 · see citing works

Opposing Roles for Membrane Bound and Soluble Fas Ligand in Glaucoma-Associated Retinal Ganglion Cell Death

Gregory, M. S., Hackett, C. G., Abernathy, E., Lee, K. S., Saff, R. R., Hohlbaum, A. M., Moody, K.-S., Hobson, M. W., Jones, A., Kolovou, P. E., et al. (2011) · PLoS ONE · doi:10.1371/journal.pone.0017659 · Cited by 94 · see citing works

Reshaping of Human Macrophage Polarization through Modulation of Glucose Catabolic Pathways

Izquierdo, E., Cuevas, V. D., Fernández‐Arroyo, S., Riera-Borrull, M., Orta‐Zavalza, E., Joven, J., Rial, E., Corbí, A. L., & Escribese, M. M. (2015) · The Journal of Immunology · doi:10.4049/jimmunol.1403045 · Cited by 90 · see citing works

Fas—Beyond Death: A regenerative role for Fas in the nervous system

Lambert, C., Landau, A. M., & Desbarats, J. (2003) · APOPTOSIS · doi:10.1023/a:1026113222478 · Cited by 86 · see citing works

Reaction of Müller cells after increased intraocular pressure in the rat retina

Kim, I., Kim, K.-Y., Joo, C. –., Lee, M.-Y., Oh, S., Chung, J. –., & Chun, M. (1998) · Experimental Brain Research · doi:10.1007/s002210050476 · Cited by 86 · see citing works

Membrane Fas Ligand Activates Innate Immunity and Terminates Ocular Immune Privilege

Gregory, M. S., Repp, A. C., Hohlbaum, A. M., Saff, R. R., Marshak‐Rothstein, A., & Ksander, B. R. (2002) · The Journal of Immunology · doi:10.4049/jimmunol.169.5.2727 · Cited by 84 · see citing works

Antioxidant Treatment Limits Neuroinflammation in Experimental Glaucoma

Yang, X., Hondur, G., & Tezel, G. (2016) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.16-19153 · Cited by 80 · see citing works

Complete Loss of Fas Ligand Gene Causes Massive Lymphoproliferation and Early Death, Indicating a Residual Activity of gld Allele

Karray, S., Kress, C., Cuvellier, S., Hue-Beauvais, C., Damotte, D., Babinet, C., & Lévi‐Strauss, M. (2004) · The Journal of Immunology · doi:10.4049/jimmunol.172.4.2118 · Cited by 79 · see citing works

Blocking Endothelin-B Receptors Rescues Retinal Ganglion Cells from Optic Nerve Injury through Suppression of Neuroinflammation

Tonari, M., Kurimoto, T., Horie, T., Sugiyama, T., Ikeda, T., & Oku, H. (2012) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.11-9415 · Cited by 71 · see citing works

New directions in the treatment of normal tension glaucoma

Caprioli, J., & Song, B. (2014) · Indian Journal of Ophthalmology · doi:10.4103/0301-4738.133481 · Cited by 61 · see citing works

Retinal glial cell responses and Fas/FasL activation in rats with chronic ocular hypertension

Ju, K. R., Kim, H. S., Kim, J., Lee, N. Y., & Park, C. K. (2006) · Brain Research · doi:10.1016/j.brainres.2006.09.022 · Cited by 60 · see citing works

Increased optic atrophy type 1 expression protects retinal ganglion cells in a mouse model of glaucoma.

Ju, W., Keun-young Kim, A., Duong‐Polk, K., Lindsey, J. D., Ellisman, M. H., & Weinreb, R. N. (2010) · PubMed Central · Cited by 58 · see citing works

Experimental Glaucoma and Optic Nerve Transection Induce Simultaneous Upregulation of Proapoptotic and Prosurvival Genes

Levkovitch-Verbin, H., Dardik, R., Vander, S., Nisgav, Y., Kalev‐Landoy, M., & Melamed, S. T. (2006) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.05-0996 · Cited by 53 · see citing works

Potential role of A2A adenosine receptor in traumatic optic neuropathy

Ahmad, S., Fatteh, N., Elsherbiny, N. M., Naime, M., Ibrahim, A. S., Elsherbini, A. M., Elshafey, S., Khan, S. H., Fulzele, S., Gonzales, J., et al. (2013) · Journal of Neuroimmunology · doi:10.1016/j.jneuroim.2013.09.015 · Cited by 51 · see citing works

Systemic Adeno-Associated Virus-Mediated Gene Therapy Preserves Retinal Ganglion Cells and Visual Function in DBA/2J Glaucomatous Mice

Sullivan, T. A., Geisert, E. E., Hines-Beard, J., & Rex, T. S. (2011) · Human Gene Therapy · doi:10.1089/hum.2011.052 · Cited by 50 · see citing works

Anti-inflammatory effect of pigment epithelium-derived factor in DBA/2J mice.

Zhou, X., Li, F., Kong, L., Chodosh, J., & Cao, W. (2009) · PubMed Central · Cited by 48 · see citing works

Angiogenesis in eye disease: immunity gained or immunity lost?

Ferguson, T. A., & Apte, R. S. (2008) · Seminars in Immunopathology · doi:10.1007/s00281-008-0113-8 · Cited by 46 · see citing works

Virus-mediated EpoR76E Therapy Slows Optic Nerve Axonopathy in Experimental Glaucoma

Bond, W. S., Hines-Beard, J., GoldenMerry, Y., Davis, M., Farooque, A., Sappington, R. M., Calkins, D. J., & Rex, T. S. (2015) · Molecular Therapy · doi:10.1038/mt.2015.198 · Cited by 42 · see citing works

Membrane-bound and soluble Fas ligands have opposite functions in photoreceptor cell death following separation from the retinal pigment epithelium

Matsumoto, H., Murakami, Y., Kataoka, K., Notomi, S., Mantopoulos, D., Trichonas, G., Miller, J. W., Gregory, M. S., Ksander, B. R., Marshak‐Rothstein, A., et al. (2015) · Cell Death and Disease · doi:10.1038/cddis.2015.334 · Cited by 42 · see citing works

Neuroprotective Effects of Transcription Factor Brn3b in an Ocular Hypertension Rat Model of Glaucoma

Stankowska, D. L., Minton, A. Z., Rutledge, M. A., Mueller, B., Phatak, N., He, S., Ma, H., Forster, M. J., Yorio, T., & Krishnamoorthy, R. R. (2015) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.14-15008 · Cited by 39 · see citing works

An open-source computational tool to automatically quantify immunolabeled retinal ganglion cells

Dordea, A. C., Bray, M., Allen, K. N., Logan, D. J., Fei, F., Malhotra, R. K., Gregory, M. S., Carpenter, A. E., & Buys, E. S. (2016) · Experimental Eye Research · doi:10.1016/j.exer.2016.04.012 · Cited by 38 · see citing works

Clinical Update on Normal Tension Glaucoma

Mudumbai, R. C. (2013) · Seminars in Ophthalmology · doi:10.3109/08820538.2013.771202 · Cited by 27 · see citing works

Non-Cleavable Mutant Fas Ligand Transfection of Donor Cornea Abrogates Ocular Immune Privilege

Sano, Y., Yamada, J., Ishino, Y., Adachi, W., Kawasaki, S., Suzuki, T., Kinoshita, S., Okuyama, T., & Azuma, N. (2002) · Experimental Eye Research · doi:10.1006/exer.2002.2044 · Cited by 16 · see citing works

Control of Ocular Tumor Growth and Metastatic Spread by Soluble and Membrane Fas Ligand

Gregory, M. S., Saff, R. R., Marshak‐Rothstein, A., & Ksander, B. R. (2007) · Cancer Research · doi:10.1158/0008-5472.can-07-0780 · Cited by 16 · see citing works

Innate immunity in the Grid2 Lc/+ mouse model of cerebellar neurodegeneration: glial CD95/CD95L plays a non-apoptotic role in persistent neuron loss-associated inflammatory reactions in the cerebellum

Garabedian, B. V.-D., Derer, P., Bailly, Y. J. R., & Mariani, J. (2013) · Journal of Neuroinflammation · doi:10.1186/1742-2094-10-65 · Cited by 11 · see citing works

Reprogramming to recover youthful epigenetic information and restore vision

Lu, Y., Brommer, B., Tian, X., Krishnan, A., Meer, M., Wang, C., Vera, D. L., Zeng, Q., Yu, D., Bonkowski, M. S., et al. (2020) · Nature · doi:10.1038/s41586-020-2975-4 · Cited by 820 · see citing works

Inflammation in Glaucoma: From the back to the front of the eye, and beyond

Baudouin, C., Kolko, M., Parsadaniantz, S. M., & Messmer, E. S. B. M. (2020) · Progress in Retinal and Eye Research · doi:10.1016/j.preteyeres.2020.100916 · Cited by 470 · see citing works

Molecular regulation of neuroinflammation in glaucoma: Current knowledge and the ongoing search for new treatment targets

Tezel, G. (2021) · Progress in Retinal and Eye Research · doi:10.1016/j.preteyeres.2021.100998 · Cited by 172 · see citing works

A small peptide antagonist of the Fas receptor inhibits neuroinflammation and prevents axon degeneration and retinal ganglion cell death in an inducible mouse model of glaucoma

Krishnan, A., Kocab, A. J., Zacks, D. N., Marshak‐Rothstein, A., & Gregory-Ksander, M. S. (2019) · Journal of Neuroinflammation · doi:10.1186/s12974-019-1576-3 · Cited by 140 · see citing works

Neuroprotection in glaucoma: Mechanisms beyond intraocular pressure lowering

Tribble, J. R., Hui, F., Quintero, H., Hajji, S. E., Bell, K. C., Polo, A. D., & Williams, P. A. (2023) · Molecular Aspects of Medicine · doi:10.1016/j.mam.2023.101193 · Cited by 115 · see citing works

Glial Cells in Glaucoma: Friends, Foes, and Potential Therapeutic Targets

García-Bermúdez, M. Y., Freude, K., Mouhammad, Z. A., van Wijngaarden, P., Martin, K., & Kolko, M. (2021) · Frontiers in Neurology · doi:10.3389/fneur.2021.624983 · Cited by 108 · see citing works

Addressing neurodegeneration in glaucoma: Mechanisms, challenges, and treatments

Ghanem, G. O. B., Wareham, L. K., & Calkins, D. J. (2024) · Progress in Retinal and Eye Research · doi:10.1016/j.preteyeres.2024.101261 · Cited by 97 · see citing works

Immune regulation of the ocular surface

Chen, Y., Wang, S., Alemi, H., Dohlman, T. H., & Dana, R. (2022) · Experimental Eye Research · doi:10.1016/j.exer.2022.109007 · Cited by 71 · see citing works

Autoimmunity in dry eye disease – An updated review of evidence on effector and memory Th17 cells in disease pathogenicity

Chen, Y., & Dana, R. (2021) · Autoimmunity Reviews · doi:10.1016/j.autrev.2021.102933 · Cited by 70 · see citing works

Retinal Ganglion Cell Survival and Axon Regeneration after Optic Nerve Injury: Role of Inflammation and Other Factors

Wong, K. A., & Benowitz, L. I. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms231710179 · Cited by 66 · see citing works

Immune Responses in the Glaucomatous Retina: Regulation and Dynamics

Shestopalov, V. I., Spurlock, M. S., Gramlich, O. W., & Kuehn, M. H. (2021) · Cells · doi:10.3390/cells10081973 · Cited by 56 · see citing works

The role of microglia in the progression of glaucomatous neurodegeneration- a review

Zeng, H.-L., & Shi, J. (2018) · International Journal of Ophthalmology · doi:10.18240/ijo.2018.01.22 · Cited by 55 · see citing works

Ultrastructural Morphology of the Optic Nerve Head in Aged and Glaucomatous Mice

Zhu, Y., Pappas, A. C., Wang, R., Seifert, P. A., Sun, D., & Jakobs, T. (2018) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.18-23885 · Cited by 45 · see citing works

Low-Intensity Pulsed Ultrasound Protects Retinal Ganglion Cell From Optic Nerve Injury Induced Apoptosis via Yes Associated Protein

Zhou, J., Liu, Y.-J., Chen, X., Zhang, X., Xu, J., Yang, K., Wang, D., Lin, S., & Ye, J. (2018) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2018.00160 · Cited by 42 · see citing works

The concept of gene therapy for glaucoma: the dream that has not come true yet

Sulak, R., Liu, X., & Smedowski, A. (2024) · Neural Regeneration Research · doi:10.4103/1673-5374.375319 · Cited by 40 · see citing works

The Role of Complement Dysregulation in Glaucoma

Hoppe, C., & Gregory-Ksander, M. S. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25042307 · Cited by 35 · see citing works

Mouse model of ocular hypertension with retinal ganglion cell degeneration

Mukai, R., Park, D. H., Okunuki, Y., Hasegawa, E., Klokman, G., Kim, C. B., Krishnan, A., Gregory-Ksander, M. S., Husain, D., Miller, J. W., et al. (2019) · PLoS ONE · doi:10.1371/journal.pone.0208713 · Cited by 35 · see citing works

T and B Lymphocyte Deficiency in Rag1−/− Mice Reduces Retinal Ganglion Cell Loss in Experimental Glaucoma

Gramlich, O. W., Godwin, C. R., Heuss, N. D., Gregerson, D. S., & Kuehn, M. H. (2020) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.61.14.18 · Cited by 34 · see citing works

Cell Death in AMD: The Rationale for Targeting Fas

Zacks, D. N., Kocab, A. J., Choi, J. J., Gregory-Ksander, M. S., Cano, M., & Handa, J. T. (2022) · Journal of Clinical Medicine · doi:10.3390/jcm11030592 · Cited by 31 · see citing works

Immunomodulatory and Antioxidant Drugs in Glaucoma Treatment

Buonfiglio, F., Pfeiffer, N., & Gericke, A. (2023) · Pharmaceuticals · doi:10.3390/ph16091193 · Cited by 32 · see citing works

Looking into the future: Gene and cell therapies for glaucoma

Komáromy, A. M., Koehl, K. L., & Park, S. A. (2021) · Veterinary Ophthalmology · doi:10.1111/vop.12858 · Cited by 29 · see citing works

Use of Gene Therapy in Retinal Ganglion Cell Neuroprotection: Current Concepts and Future Directions

Rhee, J., & Shih, K. C. (2021) · Biomolecules · doi:10.3390/biom11040581 · Cited by 29 · see citing works

Retinal Ganglion Cell Death in Glaucoma: Advances and Caveats

Yang, Y., & Sun, X. (2022) · Current Eye Research · doi:10.1080/02713683.2022.2068182 · Cited by 26 · see citing works

Molecular mechanisms of FasL-mediated ‘reverse-signaling’

Malarkannan, S. (2020) · Molecular Immunology · doi:10.1016/j.molimm.2020.08.010 · Cited by 26 · see citing works

Myeloid cells in retinal and brain degeneration

Guo, M., Schwartz, T. D., Dunaief, J. L., & Cui, Q. N. (2021) · FEBS Journal · doi:10.1111/febs.16177 · Cited by 24 · see citing works

Apoptosis in glaucoma: A new direction for the treatment of glaucoma (Review)

Xia, Q., & Zhang, D. (2024) · Molecular Medicine Reports · doi:10.3892/mmr.2024.13207 · Cited by 25 · see citing works

Reversal of ageing- and injury-induced vision loss by Tet-dependent epigenetic reprogramming

Lu, Y., Krishnan, A., Brommer, B., Tian, X., Meer, M., Vera, D. L., Wang, C., Zeng, Q., Yu, D., Bonkowski, M. S., et al. (2019) · doi:10.1101/710210 · Cited by 20 · see citing works

Challenging glaucoma with emerging therapies: an overview of advancements against the silent thief of sight

Sarkis, S., Chamard, C., Johansen, B., Daïen, V., & Michon, F. (2025) · Frontiers in Medicine · doi:10.3389/fmed.2025.1527319 · Cited by 24 · see citing works

Vitamin C protects retinal ganglion cells via SPP1 in glaucoma and after optic nerve damage

Li, S., & Jakobs, T. (2023) · Life Science Alliance · doi:10.26508/lsa.202301976 · Cited by 21 · see citing works

Neuroprotective Gene Therapy by Overexpression of the Transcription Factor MAX in Rat Models of Glaucomatous Neurodegeneration

Lani‐Louzada, R., Marra, C., Dias, M. S., Araújo, V. G., Abreu, C. A., Ribas, V. T., Adesse, D., Allodi, S., Chiodo, V. A., Hauswirth, W. W., et al. (2022) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.63.2.5 · Cited by 20 · see citing works

Molecular pathways in experimental glaucoma models

Bugara, K., Pacwa, A., & Smędowski, A. (2024) · Frontiers in Neuroscience · doi:10.3389/fnins.2024.1363170 · Cited by 17 · see citing works

Preservation of retinal structure and function in two mouse models of inherited retinal degeneration by ONL1204, an inhibitor of the Fas receptor

Yang, M.-L., Yao, J., Jia, L., Kocab, A. J., & Zacks, D. N. (2024) · Cell Death and Disease · doi:10.1038/s41419-024-06970-6 · Cited by 17 · see citing works

Soluble Fas ligand blocks destructive corneal inflammation in mouse models of corneal epithelial debridement and LPS induced keratitis

Gregory-Ksander, M. S., Perez, V. L., Marshak‐Rothstein, A., & Ksander, B. R. (2018) · Experimental Eye Research · doi:10.1016/j.exer.2018.10.013 · Cited by 17 · see citing works

Loss of Fas Receptor Function Preserves Photoreceptor Structure and Function in Two Mouse Models of Inherited Retinal Degeneration

Yao, J., Wang, T., Jia, L., Qiu, Y., & Zacks, D. N. (2022) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.63.10.5 · Cited by 14 · see citing works

sFasL—The Key to a Riddle: Immune Responses in Aging Lung and Disease

Wallach‐Dayan, S. B., Petukhov, D., Ahdut-HaCohen, R., Richter-Dayan, M., & Breuer, R. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22042177 · Cited by 14 · see citing works

Engineered bio-functional material-based nerve guide conduits for optic nerve regeneration: a view from the cellular perspective, challenges and the future outlook

Obeng, E., Shen, B., Wang, W., Xie, Z., Zhang, W., Li, Z., Yao, Q., & Wu, W. (2024) · Regenerative Biomaterials · doi:10.1093/rb/rbae133 · Cited by 13 · see citing works

Glial-mediated immune modulation in glaucomatous neurodegeneration: mechanisms and therapeutic implications

Zong, F., You, J., Wu, H., & Wang, X. (2025) · Frontiers in Immunology · doi:10.3389/fimmu.2025.1640110 · Cited by 10 · see citing works

Future directions of glaucoma treatment: emerging gene, neuroprotection, nanomedicine, stem cell, and vascular therapies

Ciociola, E. C., Fernandez, E., Kaufmann, M., & Klifto, M. R. (2023) · Current Opinion in Ophthalmology · doi:10.1097/icu.0000000000001016 · Cited by 10 · see citing works

The FasLane to ocular pathology—metalloproteinase cleavage of membrane-bound FasL determines FasL function

Gregory-Ksander, M. S., & Marshak‐Rothstein, A. (2021) · Journal of Leukocyte Biology · doi:10.1002/jlb.3ri1220-834r · Cited by 10 · see citing works

Loss of αA or αB-Crystallin Accelerates Photoreceptor Cell Death in a Mouse Model of P23H Autosomal Dominant Retinitis Pigmentosa

Wang, T., Yao, J., Jia, L., Fort, P. E., & Zacks, D. N. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms23010070 · Cited by 10 · see citing works

Making Basic Science Studies in Glaucoma More Clinically Relevant: The Need for a Consensus

Toris, C. B., Gelfman, C. M., Whitlock, A., Sponsel, W. E., & Rowe-Rendleman, C. L. (2017) · Journal of Ocular Pharmacology and Therapeutics · doi:10.1089/jop.2017.0001 · Cited by 9 · see citing works

Exome Sequencing Reveals a Heterozygous OAS3 Mutation in a Chinese Family With Juvenile-Onset Open-Angle Glaucoma

Xiao, X., Huang, C., Cao, Y., Chen, S., Xu, Y., Chen, H., Pang, C., & Zhang, M. (2019) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.19-27545 · Cited by 8 · see citing works

The Immunopathogenesis of uveitis

Han, J., Harper, J., Copland, D. A., & Maghsoudlou, P. (2026) · Frontiers in Medicine · doi:10.3389/fmed.2026.1717056 · Cited by 7 · see citing works

An Innovative In Vitro Open-Angle Glaucoma Model (IVOM) Shows Changes Induced by Increased Ocular Pressure and Oxidative Stress

Vernazza, S., Tirendi, S., Passalacqua, M., Piacente, F., Scarfı̀, S., Oddone, F., & Bassi, A. M. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms222212129 · Cited by 6 · see citing works

Neuroprotection of photoreceptors by combined inhibition of both Fas and autophagy pathways in P23H mice

Yang, M.-L., Yao, J., Jia, L., Kocab, A. J., & Zacks, D. N. (2025) · Cell Death and Disease · doi:10.1038/s41419-025-07793-9 · Cited by 4 · see citing works

PANoptosis of Retinal Ganglion Cells

Jiang, Y., Qu, W., Kong, Q., & Lu, X. (2025) · Journal of Integrative Neuroscience · doi:10.31083/jin38216 · Cited by 4 · see citing works

Dual role of microglia in glaucoma: Regulation of neuroinflammation and neuroregeneration

Li, P., Shi, X., & Prokosch, V. (2025) · Neural Regeneration Research · doi:10.4103/nrr.nrr-d-24-00876 · Cited by 5 · see citing works

Emerging Gene Therapy Technologies for Retinal Ganglion Cell Neuroprotection

Camacho, D. K., Go, C. C., Chaqour, B., Shindler, K. S., & Ross, A. G. (2023) · Journal of Neuro-Ophthalmology · doi:10.1097/wno.0000000000001955 · Cited by 4 · see citing works

Alpha-Melanocyte-Stimulating Hormone Maintains Retinal Homeostasis after Ischemia/Reperfusion

Ng, T. F., Cho, J. Y., Zhao, J. L., Gardiner, J. R., Wang, E. S., Leung, E., Xu, Z., Fineman, S. L., Lituchy, M., Lo, A., et al. (2024) · Biomolecules · doi:10.3390/biom14050525 · Cited by 4 · see citing works

Improvement of human donor retinal ganglion cell survival through modulation of microgliaPreprint

Malechka, V. V., Phay, M. H., Augustine, J., Kriukov, E., Rivera, J. D., Alt, C., Gregory-Ksander, M. S., & Baranov, P. Y. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.07.06.602307 · Cited by 3 · see citing works

Single-cell transcriptome of retinal myeloid cells in response to transplantation of human neurons reveals reversibility of microglial activationPreprint

Kriukov, E., Mukwaya, A., Cullen, P. F., Baldwin, G., Malechka, V. V., Refaian, N., Bagaev, N., Labrecque, E., Vinjamuri, S., Margeta, M. A., et al. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.05.16.654622 · Cited by 3 · see citing works

Pathophysiology of Dry Eye Disease Using Animal Models

Chen, Y., & Dana, R. (2022) · Elsevier eBooks · doi:10.1016/b978-0-323-82753-9.00001-1 · Cited by 2 · see citing works

In Vivo Characterization of ONL1204, a Small Peptide Inhibitor of the Fas Receptor, as a Potential Neuroprotective Therapy for Geographic Atrophy and Dry Age-Related Macular Degeneration

Kocab, A. J., Cano, M., Bacellar‐Galdino, M., Jamison, J. A., Brock, W. J., Zacks, D. N., & Handa, J. T. (2025) · Biomedicines · doi:10.3390/biomedicines13092052 · Cited by 2 · see citing works

Eye-brain axis: the crosstalk between neurons and immune cells

Liu, C., Fang, Z., He, Z., Mao, Y., & Yang, H. (2026) · Eye Discovery · doi:10.1016/j.edisc.2026.100023 · Cited by 1 · see citing works

Novel Therapeutic Targets for Glaucoma: Disease Modification Treatment, Neuroprotection, and Neuroregeneration

Kwong, J. M. K., & Pang, I. (2019) · Springer eBooks · doi:10.1007/978-981-13-2733-9_7 · Cited by 1 · see citing works

Small GTPase RIT1 in Mouse Retina; Cellular and Functional Analysis

Mir, S., & Andres, D. (2018) · Current Eye Research · doi:10.1080/02713683.2018.1482557 · Cited by 1 · see citing works

Faculty Opinions recommendation of Reprogramming to recover youthful epigenetic information and restore vision.

Maden, M. (2021) · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · doi:10.3410/f.739135920.793582270

Faculty Opinions recommendation of Reprogramming to recover youthful epigenetic information and restore vision.

Liu, P. (2020) · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · doi:10.3410/f.739135920.793580966

Assessment Of Soluble Fas Ligand In Patients With Chronic Myeloid Leukemia

Yasir, S. R. (2022) · Medical Science Journal for Advance Research · doi:10.46966/msjar.v3i4.79

Fas Ligand enhances vessel maturation and inhibits vascular leakage associated with age-related macular degeneration

Koirala, A., Marshak‐Rothstein, A., Ksander, B. R., & Gregory-Ksander, M. S. (2026) · Frontiers in Immunology · doi:10.3389/fimmu.2026.1898554

Gene Expression and Editing in Mammalian Retinal Ganglion Cells

Tran, N. M., Xu, X., Qi, L. S., & Hu, Y. (2024) · Essentials in ophthalmology/Essentials ophthalmology · doi:10.1007/978-981-99-4436-1_19

Caspase-8-mediated inflammation but not apoptosis drives death of retinal ganglion cells and loss of visual function in glaucomaaPreprint

Guo, Y., Verma, B., Shrestha, M., Marshak‐Rothstein, A., & Gregory-Ksander, M. S. (2024) · Research Square · doi:10.21203/rs.3.rs-4409426/v1

A connection between levels of soluble Fas and Fas ligand in the aqueous humor and the parameters of structural and functional damage of glaucoma patients

Trenkić-Božinović, M., Jevtović−Stoimenov, T., Bašić, J., Stamenković, M., Jocic-Djordjevic, J., & Trenkić, M. S. (2024) · Srpski arhiv za celokupno lekarstvo · doi:10.2298/sarh231022061t

CD40–CD154 Interactions Induced Progressive Neurodegeneration in Acute Ocular Hypertension Mice

Tang, J., Feng, Z., Jiang, N., & Zhao, G. (2025) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.66.13.39

Gene therapy in ophthalmology: new prospects

Kharisova, C. B., Kitaeva, K. V., Solovyeva, V. V., Фаисович, А. Р., & Rizvanov, A. A. (2026) · Kazan medical journal · doi:10.17816/kmj677044

Glaucoma and Autoimmunity: Immunopathogenic Mechanisms and Emerging Immunomodulatory Therapies

Wang, M., Liu, C., & Wei, X. (2026) · Biomedicines · doi:10.3390/biomedicines14061209

Experimental models to study oxidative stress in glaucoma: integrating in vitro, in vivo, and clinical studies

Moksha, L., Zhu, Y., Salowe, R., Vrathasha, V., Nair, R. M., He, J., Halimitabrizi, M., Rice, G., Quinn, P. M. J., Cheng, Y., et al. (2026) · Frontiers in Pharmacology · doi:10.3389/fphar.2026.1893993

Single-cell transcriptomics reveals reversible microglia/macrophage activation after human retinal neuron transplantation into mouse retina

Kriukov, E., Mukwaya, A., Cullen, P., Kam, H. T., Baldwin, G., Malechka, V. V., Refaian, N., Bagaev, N., Labrecque, E., Vinjamuri, S., et al. (2026) · iScience · doi:10.1016/j.isci.2026.117232 · Cited by 4 · see citing works

Opposing Roles for Membrane Bound and Soluble Fas Ligand in Glaucoma-Associated Retinal Ganglion Cell Death

Gregory, M. S., Hackett, C. G., Abernathy, E., Lee, K. S., Saff, R. R., Hohlbaum, A. M., Moody, K.-S., Hobson, M. W., Jones, A., Kolovou, P. E., et al. (2011) · PLoS ONE · doi:10.1371/journal.pone.0017659 · Cited by 94 · see citing works

Opposing Roles for Membrane Bound and Soluble Fas Ligand in Glaucoma-Associated Retinal Ganglion Cell

Gregory, M. S., Hackett, C. G., Abernathy, E. F., Lee, K. S., Saff, R. R., Hohlbaum, A. M., Moody, K.-S. L., Hobson, M. W., Jones, E., Kolovou, P., et al. (2013)

A small peptide antagonist of the Fas receptor inhibits neuroinflammation and prevents axon degeneration and retinal ganglion cell death in an inducible mouse model of glaucoma

Krishnan, A., Kocab, A. J., Zacks, D. N., Marshak‐Rothstein, A., & Gregory-Ksander, M. S. (2019) · Journal of Neuroinflammation · doi:10.1186/s12974-019-1576-3 · Cited by 140 · see citing works

Soluble Fas ligand provides long-term protection in a chronic mouse model of glaucoma by inhibiting glial activation, inflammation, and apoptosis

Gregory-Ksander, M. S., Fei, F., Marshak‐Rothstein, A., Ksander, B. R., & Krishnan, A. (2016) · Investigative Ophthalmology & Visual Science · Cited by 2 · see citing works

Soluble Fas ligand is a neuroprotective molecule critical in restricting glaucomatous damage to retinal ganglion cells

Krishnan, A., Jones, A., Marshak‐Rothstein, A., Ksander, B. R., & Gregory-Ksander, M. S. (2014) · Investigative Ophthalmology & Visual Science