The DOI matches its Crossref record; 49 of the 49 references it cites were found in a registry or an index.
Of Mice, Dirty Mice, and Men: Using Mice To Understand Human Immunology
Open accessAbstract
Mouse models have enabled breakthroughs in our understanding of the immune system, but it has become increasingly popular to emphasize their shortcomings when translating observations to humans. This review provides a brief summary of mouse natural history, husbandry, and the pros and cons of pursuing basic research in mice versus humans. Opportunities are discussed for extending the predictive translational value of mouse research, with an emphasis on exploitation of a “dirty” mouse model that better mimics the diverse infectious history that is typical of most humans.
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Cites
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Cited by
Therapeutic strategies targeting inflammation and immunity in atherosclerosis: how to proceed?
Engelen, S. E., Robinson, A. J. B., Zurke, Y.-X., & Monaco, C. (2022) · Nature Reviews Cardiology · doi:10.1038/s41569-021-00668-4 · Cited by 425
Huggins, M. A., Sjaastad, F. V., Pierson, M., Kucaba, T. A., Swanson, W., Staley, C., Weingarden, A. R., Jensen, I. J., Danahy, D. B., Badovinac, V. P., et al. (2019) · Cell Reports · doi:10.1016/j.celrep.2019.07.028 · Cited by 114
Diverse CD8 T Cell Responses to Viral Infection Revealed by the Collaborative Cross
Martin, M. D., Sompallae, R., Winborn, C. S., Harty, J. T., & Badovinac, V. P. (2020) · Cell Reports · doi:10.1016/j.celrep.2020.03.072 · Cited by 21
Homeostasis and Durability of T-Cell Memory—The Resting and the Restless T-Cell Memory
Radbruch, A., McGrath, M. A., Siracusa, F., Hoffmann, U., Sercan-Alp, Ö., Hutloff, A., Tokoyoda, K., Chang, H.-D., & Dong, J. (2021) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a038083 · Cited by 16
Metadata
- Authors
- Masopust, D., Sivula, C. P., & Jameson, S. C.
- Venue
- The Journal of Immunology
- Publisher
- Oxford University Press (OUP)
- Published
- 2017-07
- Volume
- 199
- Issue
- 2
- Pages
- 383-388
- ISSN
- 0022-1767 (ISSN-L)
- 1550-6606
- OpenAlex
- W2735805106
- Cited by
- 293
- References
- 49
- FWCI
- 31.70
- Type
- journal article
- Language
- en
- Open access
- green
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- Masopust, D., Sivula, C. P., & Jameson, S. C. (2017). Of Mice, Dirty Mice, and Men: Using Mice To Understand Human Immunology. The Journal of Immunology. https://doi.org/10.4049/jimmunol.1700453
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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