Cited by 563Antimicrobial Resistance in StaphylococcusNeutrophil, Myeloperoxidase and Oxidative MechanismsStreptococcal Infections and Treatments

The DOI matches its Crossref record; 57 of the 58 references it cites were found in a registry or an index.

Insights into Mechanisms Used by Staphylococcus aureus to Avoid Destruction by Human Neutrophils

Voyich, Jovanka M, Braughton, Kevin R, Sturdevant, Daniel E, Whitney, Adeline R, Saïd-Salim, Battouli, Porcella, Stephen F, Long, R Daniel, Dorward, David W, Gardner, Donald J, Kreiswirth, Barry N, Musser, James M, DeLeo, Frank R·2005·The Journal of Immunology

DOI 10.4049/jimmunol.175.6.3907

Open this paper in CoChat — free account

Abstract

Polymorphonuclear leukocytes (PMNs, or neutrophils) are critical for human innate immunity and kill most invading bacteria. However, pathogens such as Staphylococcus aureus avoid destruction by PMNs to survive, thereby causing human infections. The molecular mechanisms used by pathogens to circumvent killing by the immune system remain largely undefined. To that end, we studied S. aureus pathogenesis and bacteria-PMN interactions using strains originally isolated from individuals with community-acquired (CA) and hospital-acquired infections. Compared with strains from hospital infections (COL and MRSA252), strain MW2 and a methicillin-susceptible relative, MnCop, were significantly more virulent in a mouse model of S. aureus infection, and caused the greatest level of pathology in major vital organs. Although phagocytosis of each strain triggered production of reactive oxygen species and granule-phagosome fusion, those from CA infections were significantly more resistant to killing by human PMNs and caused greater host cell lysis. Microarray analysis of the strains during neutrophil phagocytosis identified genes comprising a global S. aureus response to human innate host defense. Genes involved in capsule synthesis, gene regulation, oxidative stress, and virulence, were up-regulated following ingestion of the pathogen. Notably, phagocytosis of strains from CA infections induced changes in gene expression not observed in the other strains, including up-regulation of genes encoding virulence factors and hypothetical proteins. Our studies reveal a gene transcription program in a prominent human pathogen that likely contributes to evasion of innate host defense.

Integrity signals

Registry

Crossref · 10.4049/jimmunol.175.6.3907

Cites

57 of 57 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Staphylococcus aureus Infections
Lowy, F. D. (1998) · New England Journal of Medicine · doi:10.1056/nejm199808203390806 · Cited by 6,018
Quantitative Relationships Between Circulating Leukocytes and Infection in Patients with Acute Leukemia
Bodey, G. P., BUCKLEY, M., SATHE, Y. S., & FREIREICH, E. J. (1966) · Annals of Internal Medicine · doi:10.7326/0003-4819-64-2-328 · Cited by 2,465
Exotoxins of Staphylococcus aureus
Dinges, M. M., Orwin, P. M., & Schlievert, P. M. (2000) · Clinical Microbiology Reviews · doi:10.1128/cmr.13.1.16-34.2000 · Cited by 1,837
Community-Acquired Methicillin-ResistantStaphylococcus aureusCarrying Panton-Valentine Leukocidin Genes: Worldwide Emergence
Vandenesch, F., Naimi, T. S., Enright, M. C., Lina, G., Nimmo, G. R., Heffernan, H., Liassine, N., Bes, M., Greenland, T., Reverdy, M. E., et al. (2003) · Emerging infectious diseases · doi:10.3201/eid0908.030089 · Cited by 1,718
Comparison of Community- and Health Care–Associated Methicillin-Resistant <EMPH TYPE="ITAL">Staphylococcus aureus</EMPH> Infection
Naimi, T. S. (2003) · JAMA · doi:10.1001/jama.290.22.2976 · Cited by 1,688
Association between Staphylococcus aureus strains carrying gene for Panton-Valentine leukocidin and highly lethal necrotising pneumonia in young immunocompetent patients
Gillet, Y., Issartel, B., Vanhems, P., Fournet, J.-C., Lina, G., Bes, M., Vandenesch, F., Piémont, Y., Brousse, N., Floret, D., et al. (2002) · The Lancet · doi:10.1016/s0140-6736(02)07877-7 · Cited by 1,514
Methicillin-Resistant Staphylococcus aureus Disease in Three Communities
Fridkin, S. K., Hageman, J. C., Morrison, M., Sanza, L. T., Como-Sabetti, K., Jernigan, J. A., Harriman, K., Harrison, L. H., Lynfield, R., & Farley, M. M. (2005) · New England Journal of Medicine · doi:10.1056/nejmoa043252 · Cited by 1,493
Community-Acquired Methicillin-Resistant <EMPH TYPE="ITAL">Staphylococcus aureus</EMPH> in Children With No Identified Predisposing Risk
Herold, B. C. (1998) · JAMA · doi:10.1001/jama.279.8.593 · Cited by 1,412
Pulsed-Field Gel Electrophoresis Typing of Oxacillin-ResistantStaphylococcus aureusIsolates from the United States: Establishing a National Database
McDougal, L. K., Steward, C. D., Killgore, G., Chaitram, J. M., McAllister, S. K., & Tenover, F. C. (2003) · Journal of Clinical Microbiology · doi:10.1128/jcm.41.11.5113-5120.2003 · Cited by 1,410
Genome and virulence determinants of high virulence community-acquired MRSA
Baba, T., Takeuchi, F., Kuroda, M., Yuzawa, H., Aoki, K.-I., Oguchi, A., Nagai, Y., Iwama, N., Asano, K., Naimi, T. S., et al. (2002) · The Lancet · doi:10.1016/s0140-6736(02)08713-5 · Cited by 1,356

Show all 58 references

Research works printed but not linked: 56

1998, N. Engl. J. Med., 520
2003, Infect. Control Hosp. Epidemiol., 451
2000, Clin. Microbiol. Rev., 16
2004, Proc. Natl. Acad. Sci. USA, 12312
2002, Lancet, 1819
2001, Proc. Natl. Acad. Sci. USA, 8821
1999, J. Am. Med. Assoc., 1123
1989, Am. J. Dis. Child., 848
2005, N. Engl. J. Med., 1445
2005, N. Engl. J. Med., 468
2004, Clin. Infect. Dis., 1446
2005, Clin. Infect. Dis., 100
2004, Proc. Natl. Acad. Sci. USA, 9786
1979, Infect. Immun., 902
1998, J. Am. Med. Assoc., 593
2003, J. Clin. Microbiol., 5113
2003, Proc. Natl. Acad. Sci. USA, 10948
1999, J. Immunol., 6732
2003, Proc. Natl. Acad. Sci. USA, 1996
2002, Lancet, 753
2000, J. Immunol., 3713
2003, FEBS Lett., 54
2004, Clin. Microbiol. Rev., 218
2003, J. Bacteriol., 6686
2003, Mol. Microbiol., 1429
2003, Mol. Microbiol., 807
2004, FEMS Immunol. Med. Microbiol., 1
2004, J. Bacteriol., 3029
2000, J. Bacteriol., 4822
2000, Trends Microbiol., 274
2002, Proc. Natl. Acad. Sci. USA, 6901
2003, J. Leukocyte Biol., 315
2003, J. Immunol., 3357
2004, J. Immunol., 636
2004, Biochem. Soc. Trans., 474
2005, N. Engl. J. Med., 1485
2005, N. Engl. J. Med., 1436
2003, J. Am. Med. Assoc., 2976
2003, Emerg. Infect. Dis., 978
2001, Clin. Infect. Dis., 990
2004, J. Clin. Microbiol., 5673
2001, J. Am. Med. Assoc., 1201
1999, Clin. Infect. Dis., 797
2000, N. Engl. J. Med., 1703
1930, J. Am. Med. Assoc., 780
1966, Ann. Intern. Med., 328
1979, Medicine (Baltimore)., 128
1976, Am. J. Med., 849
2000, Infect. Immun., 6162
1997, Infect. Immun., 2517
2004, J. Immunol., 1194
2004, J. Clin. Invest., 1732
2004, J. Clin. Microbiol., 3752
2002, Clin. Infect. Dis., 819
2005, J. Clin. Microbiol., 3373
2004, Microbes. Infect., 1117

Sorted by citations

Items 301–400 of 559

Synthesis of new triazole fused imidazo[2,1-b]thiazole hybrids with emphasis on Staphylococcus aureus virulence factors
Shareef, M. A., Kanugala, S., Sayeed, I. B., Khan, I., Ganapathi, T., Akbar, S., Kumar, C. G., Kamal, Ä., & Babu, B. N. (2019) · Bioorganic & Medicinal Chemistry Letters · doi:10.1016/j.bmcl.2019.08.025 · Cited by 33
mgrA regulates staphylococcal virulence important for induction and progression of septic arthritis and sepsis
Jonsson, I., Lindholm, C., Luong, T. T., Lee, C. Y., & Tarkowski, A. (2008) · Microbes and Infection · doi:10.1016/j.micinf.2008.07.026 · Cited by 32
RNA profiling in host–pathogen interactions
Waddell, S. J., Butcher, P. D., & Stoker, N. G. (2007) · Current Opinion in Microbiology · doi:10.1016/j.mib.2007.05.013 · Cited by 32
Random mutagenesis and topology analysis of the autoinducing peptide biosynthesis proteins in S taphylococcus aureus
Thoendel, M., & Horswill, A. R. (2012) · Molecular Microbiology · doi:10.1111/mmi.12100 · Cited by 32
Skin Structure and Function
Brodell, L. A., & Rosenthal, K. S. (2008) · Infectious Diseases in Clinical Practice · doi:10.1097/ipc.0b013e3181660bf4 · Cited by 34
Signatures of cytoplasmic proteins in the exoproteome distinguish community- and hospital-associated methicillin-resistantStaphylococcus aureusUSA300 lineages
Mekonnen, S. A., Medina, L. M. P., Glasner, C., Tsompanidou, E., de Jong, A., Grasso, S., Schaffer, M., Mäder, U., Larsen, A. R., Gumpert, H., et al. (2017) · Virulence · doi:10.1080/21505594.2017.1325064 · Cited by 32
MsaB activates capsule production at the transcription level in Staphylococcus aureus
Batte, J. L., Samanta, D., & Elasri, M. O. (2016) · Microbiology · doi:10.1099/mic.0.000243 · Cited by 31
Staphylococcal DNA Repair Is Required for Infection
Ha, K. P., Clarke, R. S., Kim, G. L., Brittan, J. L., Rowley, J. E., Mavridou, D. A. I., Parker, D., Clarke, T. B., Nobbs, A. H., & Edwards, A. M. (2020) · mBio · doi:10.1128/mbio.02288-20 · Cited by 33
Copper Resistance Promotes Fitness of Methicillin-Resistant Staphylococcus aureus during Urinary Tract Infection
Saenkham, P., Hyre, A. N., Hanson, B. S., Donati, G. L., Adams, L. G., Ryan, C., Londoño, A., Moustafa, A. M., Planet, P. J., & Subashchandrabose, S. (2021) · mBio · doi:10.1128/mbio.02038-21 · Cited by 30
Nano-layered magnesium fluoride reservoirs on biomaterial surfaces strengthen polymorphonuclear leukocyte resistance to bacterial pathogens
Guo, G., Zhou, H., Wang, Q., Wang, J., Tan, J., Li, J., Jin, P., & Shen, H. (2016) · Nanoscale · doi:10.1039/c6nr07729c · Cited by 30
Hydrophobic but not hydrophilic statins enhance phagocytosis and decrease apoptosis of human peripheral blood cells in vitro
Salman, H., Bergman, M., Djaldetti, M., & Bessler, H. (2007) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2007.07.007 · Cited by 29
Modulation of virulence gene expression in Staphylococcus aureus by interleukin-1β: Novel implications in bacterial pathogenesis
Kanangat, S., Postlethwaite, A. E., Cholera, S., Williams, L. D., & Schaberg, D. R. (2007) · Microbes and Infection · doi:10.1016/j.micinf.2006.12.018 · Cited by 29
Effect of d -Alanylation of (Lipo)Teichoic Acids of Staphylococcus aureus on Host Secretory Phospholipase A2 Action before and after Phagocytosis by Human Neutrophils
Hunt, C. L., Nauseef, W. M., & Weiss, J. P. (2006) · The Journal of Immunology · doi:10.4049/jimmunol.176.8.4987 · Cited by 28
The Pathogenicity of Pseudomonas syringae MB03 against Caenorhabditis elegans and the Transcriptional Response of Nematicidal Genes upon Different Nutritional Conditions
Ali, M., Sun, Y., Xie, L., Yu, H., Bashir, A., & Li, L. (2016) · Frontiers in Microbiology · doi:10.3389/fmicb.2016.00805 · Cited by 28
Staphylococcus aureus accelerates an experimental allergic conjunctivitis by Toll-like receptor 2-dependent manner
Chung, S., Nam, K., & Kweon, M. (2009) · Clinical Immunology · doi:10.1016/j.clim.2008.11.005 · Cited by 28
Potential antimicrobial agents from triazole-functionalized 2H-benzo[b][1,4]oxazin-3(4H)-ones
Bollu, R., Banu, S., Bantu, R., Reddy, A. G., Nagarapu, L., Sirisha, K., Kumar, C. G., Gunda, S. K., & Shaik, K. (2017) · Bioorganic & Medicinal Chemistry Letters · doi:10.1016/j.bmcl.2017.10.061 · Cited by 27
Inside the phagosome: A bacterial perspective
Hampton, M. B., & Dickerhof, N. (2023) · Immunological Reviews · doi:10.1111/imr.13182 · Cited by 28
Insights into the Staphylococcus aureus-Host Interface: Global Changes in Host and Pathogen Gene Expression in a Rabbit Skin Infection Model
Małachowa, N., Kobayashi, S. D., Sturdevant, D. E., Scott, D. P., & DeLeo, F. R. (2015) · PLoS ONE · doi:10.1371/journal.pone.0117713 · Cited by 27
Self-citation
Structure Analysis of the Staphylococcus aureus UDP-N-acetyl-mannosamine Dehydrogenase Cap5O Involved in Capsular Polysaccharide Biosynthesis
Gruszczyk, J., Fleurie, A., Olivares‐Illana, V., Béchet, E., Zanella‐Cléon, I., Moréra, S., Meyer, P., Pompidor, G., Kahn, R., Grangeasse, C., et al. (2011) · Journal of Biological Chemistry · doi:10.1074/jbc.m110.216002 · Cited by 27
NLRP3 Inflammasome Is a Target for Development of Broad-Spectrum Anti-Infective Drugs
Thacker, J. D., Balin, B. J., Appelt, D. M., Sassi‐Gaha, S., Purohit, M., Rest, R. F., & Artlett, C. M. (2012) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.06372-11 · Cited by 27
Somatic cell scores and clinical signs following experimental intramammary infection of dairy cows with a Staphylococcus aureus small colony variant (S. aureus SCV) in comparison to other bovine strains
Atalla, H., Gyles, C. L., Wilkie, B. N., Leslie, K. E., & Mallard, B. A. (2009) · Veterinary Microbiology · doi:10.1016/j.vetmic.2009.01.027 · Cited by 27
Regulation of phagocyte lifespan in the lung during bacterial infection
Dockrell, D. H., & Whyte, M. K. B. (2006) · Journal of Leukocyte Biology · doi:10.1189/jlb.1005555 · Cited by 27
Neutrophil evasion strategies by Streptococcus pneumoniae and Staphylococcus aureus
Lewis, M. L., & Surewaard, B. G. J. (2017) · Cell and Tissue Research · doi:10.1007/s00441-017-2737-2 · Cited by 29
NET Confusion
Małachowa, N., Kobayashi, S. D., Quinn, M. T., & DeLeo, F. R. (2016) · Frontiers in Immunology · doi:10.3389/fimmu.2016.00259 · Cited by 32
Self-citation
Staphylococcal superantigen-like protein 13 activates neutrophils via formyl peptide receptor 2
Zhao, Y., van Kessel, K. P. M., de Haas, C. J. C., Rogers, M. R. C., van Strijp, J. A. G., & Haas, P. (2018) · Cellular Microbiology · doi:10.1111/cmi.12941 · Cited by 26
DksA Controls the Response of the Lyme Disease Spirochete Borrelia burgdorferi to Starvation
Boyle, W. K., Groshong, A. M., Drecktrah, D., Boylan, J. A., Gherardini, F. C., Blevins, J. S., Samuels, D. S., & Bourret, T. J. (2018) · Journal of Bacteriology · doi:10.1128/jb.00582-18 · Cited by 26
Epidemiology and Virulence of Community-Associated MRSA
Kennedy, A. D., & DeLeo, F. R. (2009) · Clinical Microbiology Newsletter · doi:10.1016/j.clinmicnews.2009.09.004 · Cited by 28
Self-citation
Separately or Combined, LukG/LukH Is Functionally Unique Compared to Other Staphylococcal Bicomponent Leukotoxins
Yanai, M., Rocha, M. A., Matolek, A. Z., Chintalacharuvu, A., Taira, Y., Chintalacharuvu, K. R., & Beenhouwer, D. O. (2014) · PLoS ONE · doi:10.1371/journal.pone.0089308 · Cited by 25
Virus-Like Particle-Induced Protection Against MRSA Pneumonia Is Dependent on IL-13 and Enhancement of Phagocyte Function
Rynda‐Apple, A., Dobrinen, E., McAlpine, M., Read, A., Harmsen, A. L., Richert, L. E., Calverley, M., Pallister, K. B., Voyich, J. M., Wiley, J. A., et al. (2012) · American Journal Of Pathology · doi:10.1016/j.ajpath.2012.03.018 · Cited by 25
Self-citation
Assessment of virulence diversity of methicillin-resistant Staphylococcus aureus strains with a Drosophila melanogaster infection model
Wu, K., Conly, J. M., Surette, M. G., Sibley, C. D., Elsayed, S., & Zhang, K. (2012) · BMC Microbiology · doi:10.1186/1471-2180-12-274 · Cited by 25
Possible Role of Toll‐like Receptor‐2 in the Intracellular Survival of S taphylococcus aureus in Murine Peritoneal Macrophages: Involvement of Cytokines and Anti‐Oxidant Enzymes
Bishayi, B., Bandyopadhyay, D., Majhi, A., & Adhikary, R. (2014) · Scandinavian Journal of Immunology · doi:10.1111/sji.12195 · Cited by 24
Preparing the Bowel for Surgery: Learning from the Past and Planning for the Future
Alverdy, J. C., Hyman, N., Gilbert, J. A., Luo, J. N., & Krezalek, M. A. (2017) · Journal of the American College of Surgeons · doi:10.1016/j.jamcollsurg.2017.05.005 · Cited by 24
Impact of Bicarbonate on PBP2a Production, Maturation, and Functionality in Methicillin-Resistant Staphylococcus aureus
Ersoy, S. C., Chambers, H. F. “., Proctor, R. A., Rosato, A. E., Mishra, N. N., Xiong, Y. Q., & Bayer, A. S. (2021) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.02621-20 · Cited by 23
Bacterial Outer Membrane‐Based Biomimetic Immune Adaptors: Mild Immunomodulatory and Bacterial Targeted Delivery Strategy Against Implant‐Related Infections
Ding, C., He, R., Cheng, T., Wang, J., Liu, X., Guo, G., & Chen, Y. (2023) · Advanced Functional Materials · doi:10.1002/adfm.202304168 · Cited by 23
Viral hemagglutinin is involved in promoting the internalisation of Staphylococcus aureus into human pneumocytes during influenza A H1N1 virus infection
Passariello, C., Nencioni, L., Sgarbanti, R., Ranieri, D., Torrisi, M. R., Ripa, S., Garaci, E., & Palamara, A. T. (2010) · International Journal of Medical Microbiology · doi:10.1016/j.ijmm.2010.06.008 · Cited by 23
MsaB and CodY Interact To Regulate Staphylococcus aureus Capsule in a Nutrient-Dependent Manner
Batte, J. L., Sahukhal, G. S., & Elasri, M. O. (2018) · Journal of Bacteriology · doi:10.1128/jb.00294-18 · Cited by 23
Studying Interactions of Staphylococcus aureus with Neutrophils by Flow Cytometry and Time Lapse Microscopy
Surewaard, B. G. J., van Strijp, J. A. G., & Nijland, R. (2013) · Journal of Visualized Experiments · doi:10.3791/50788 · Cited by 23
For the Greater (Bacterial) Good: Heterogeneous Expression of Energetically Costly Virulence Factors
Davis, K. M. (2020) · Infection and Immunity · doi:10.1128/iai.00911-19 · Cited by 22
MerA functions as a hypothiocyanous acid reductase and defense mechanism in Staphylococcus aureus
Shearer, H. L., Loi, V. V., Weiland, P. S., Bange, G., Altegoer, F., Hampton, M. B., Antelmann, H., & Dickerhof, N. (2023) · Molecular Microbiology · doi:10.1111/mmi.15035 · Cited by 22
Initial cytoplasmic and phagosomal consequences of human neutrophil exposure to Staphylococcus epidermidis
Bernardo, J., Long, H. J., & Simons, E. R. (2009) · Cytometry Part A · doi:10.1002/cyto.a.20827 · Cited by 22
Staphylococcus aureusInhibits Neutrophil-derived IL-8 to Promote Cell Death
Zurek, O. W., Pallister, K. B., & Voyich, J. M. (2015) · The Journal of Infectious Diseases · doi:10.1093/infdis/jiv124 · Cited by 22
Self-citation
Two dimensional electrophoresis of the exo-proteome produced from community acquired methicillin resistant Staphylococcus aureus belonging to clonal complex 80
Enany, S., Yoshida, Y., Magdeldin, S., Bo, X., Zhang, Y., Enany, M. E., & Yamamoto, T. (2013) · Microbiological Research · doi:10.1016/j.micres.2013.03.004 · Cited by 22
NEUTROPHIL APOPTOSIS IN INFECTIOUS DISEASE
Anwar, S., & Whyte, M. K. B. (2007) · Experimental Lung Research · doi:10.1080/01902140701756620 · Cited by 22
The impact of α-toxin on host cell plasma membrane permeability and cytokine expression during human blood infection by CA-MRSA USA300
Nygaard, T. K., Pallister, K. B., Zurek, O. W., & Voyich, J. M. (2013) · Journal of Leukocyte Biology · doi:10.1189/jlb.0213080 · Cited by 21
Self-citation
Antioxidant Functions of Nitric Oxide Synthase in a Methicillin SensitiveStaphylococcus aureus
Vaish, M., & Singh, V. K. (2013) · International Journal of Microbiology · doi:10.1155/2013/312146 · Cited by 21
Nanomaterials for Anti-Infection in Orthopedic Implants: A Review
Sui, J., Hou, Y., Chen, M., Zheng, Z., Meng, X., Liu, L., Huo, S., Liu, S., & Zhang, H. (2024) · Coatings · doi:10.3390/coatings14030254 · Cited by 21
Bacteremia and endocarditis due to methicillin-resistant Staphylococcus aureus: the potential role of daptomycin.
Bamberger, D. M. (2007) · PubMed Central · Cited by 20
Characterization of Yersinia pestis Interactions with Human Neutrophils In vitro
Dudte, S. C., Hinnebusch, B. J., & Shannon, J. G. (2017) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2017.00358 · Cited by 20
PtpA, a secreted tyrosine phosphatase from Staphylococcus aureus, contributes to virulence and interacts with coronin-1A during infection
Gannoun-Zaki, L., Pätzold, L., Huc-Brandt, S., Baronian, G., Elhawy, M. I., Gaupp, R., Martin, M., Blanc‐Potard, A., Letourneur, F., Bischoff, M., et al. (2018) · Journal of Biological Chemistry · doi:10.1074/jbc.ra118.003555 · Cited by 21
The Accessory Gene saeP of the SaeR/S Two-Component Gene Regulatory System Impacts Staphylococcus aureus Virulence During Neutrophil Interaction
Collins, M. M., Behera, R. K., Pallister, K. B., Evans, T. J., Burroughs, O. S., Flack, C. E., Guerra, F. E., Pullman, W., Cone, B., Dankoff, J. G., et al. (2020) · Frontiers in Microbiology · doi:10.3389/fmicb.2020.00561 · Cited by 20
Self-citation
The Role of Mcl-1 inS. aureus-Induced Cytoprotection of Infected Macrophages
Kozieł, J., Kmiecik, K., Chmiest, D., Maresz, K., Mizgalska, D., Maciag-Gudowska, A., Mydel, P. M., & Potempa, J. (2013) · Mediators of Inflammation · doi:10.1155/2013/427021 · Cited by 20
Virulence potential of Staphylococcus aureus isolates from Buruli ulcer patients
Amissah, N. A., Chlebowicz, M. A., Ablordey, A. S., Tetteh, C. S., Prah, I., van der Werf, T. S., Friedrich, A. W., van Dijl, J. M., Stienstra, Y., & Rossen, J. W. A. (2017) · International Journal of Medical Microbiology · doi:10.1016/j.ijmm.2017.04.002 · Cited by 20
Mesenchymal Stromal/Stem Cell and Minocycline-Loaded Hydrogels Inhibit the Growth of Staphylococcus aureus that Evades Immunomodulation of Blood-Derived Leukocytes
Guerra, A. D., Cantu, D. A., Vecchi, J. T., Rose, W. E., Hematti, P., & Kao, W. J. (2015) · The AAPS Journal · doi:10.1208/s12248-015-9728-6 · Cited by 19
Community-associated methicillin-resistant Staphylococcus aureus infection of diabetic foot ulcers in an eastern diabetic foot center in a tertiary hospital in China: a retrospective study
Chen, Y., Yang, J., Wang, Y., You, J., Zhu, W., Liu, C., Luan, Y., Li, L., & Li, H. (2023) · BMC Infectious Diseases · doi:10.1186/s12879-023-08631-z · Cited by 19
I n Vitro Anti-inflammatory and Immunomodulatory Effects of Ciprofloxacin or Azithromycin in Staphylococcus aureus-Stimulated Murine Macrophages are Beneficial in the Presence of Cytochalasin D
Dey, S., Majhi, A., Mahanti, S., Dey, I., & Bishayi, B. (2014) · Inflammation · doi:10.1007/s10753-014-0070-4 · Cited by 19
Signaling mechanism by the Staphylococcus aureus two-component system LytSR: role of acetyl phosphate in bypassing the cell membrane electrical potential sensor LytS
Patel, K. H., & Golemi, D. (2015) · F1000Research · doi:10.12688/f1000research.6213.1 · Cited by 19
Effects of chronic Staphylococcus aureus infection on immunological parameters and functionality of macrophages isolated from bovine mammary secretions
Renna, M. S., Silvestrini, P., Beccaria, C., Velázquez, N. S., Baravalle, C., Engler, C., Pereyra, E. A. L., Calvinho, L. F., & Dallard, B. E. (2019) · Microbial Pathogenesis · doi:10.1016/j.micpath.2019.103743 · Cited by 19
A MRSA-terious enemy among us: Boosting MRSA vaccines
Kobayashi, S. D., & DeLeo, F. R. (2011) · Nature Medicine · doi:10.1038/nm0211-168 · Cited by 18
Self-citation
Binding Mode Characterization of Novel RNA Polymerase Inhibitors Using a Combined Biochemical and NMR Approach
Fruth, M., Plaza, A., Hinsberger, S., Sahner, J. H., Haupenthal, J., Bischoff, M., Jansen, R., Müller, R., & Hartmann, R. W. (2014) · ACS Chemical Biology · doi:10.1021/cb5005433 · Cited by 18
A novel templates of piperazinyl-1,2-dihydroquinoline-3-carboxylates: Synthesis, anti-microbial evaluation and molecular docking studies
Banu, S., Bollu, R., Naseema, M., Gomedhika, P. M., Nagarapu, L., Sirisha, K., Kumar, C. G., & Gundasw, S. K. (2018) · Bioorganic & Medicinal Chemistry Letters · doi:10.1016/j.bmcl.2018.03.007 · Cited by 18
Living bacteria rheology: Population growth, aggregation patterns, and collective behavior under different shear flows
Patrício, P., Almeida, P. L., Portela, R., Sobral, R. G., Grilo, I. R., Cidade, M. T., & Leal, C. R. (2014) · Physical Review E · doi:10.1103/physreve.90.022720 · Cited by 18
Novel Synthetic (Poly)Glycerolphosphate-Based Antistaphylococcal Conjugate Vaccine
Chen, Q., Dintaman, J. M., Lees, A., Sen, G., Schwartz, D. A., Shirtliff, M. E., Park, S., Lee, J. C., Mond, J. J., & Snapper, C. M. (2013) · Infection and Immunity · doi:10.1128/iai.00271-13 · Cited by 18
Structural studies of Staphylococcus aureus Sortase inhibiton via Conus venom peptides
Younis, S., Taj, S., & Rashid, S. (2019) · Archives of Biochemistry and Biophysics · doi:10.1016/j.abb.2019.06.003 · Cited by 17
Biofilm formation by Staphylococcus aureus is triggered by a drop in the levels of a cyclic dinucleotide
Syed, A. K., Baral, R., Vlack, E. R. V., Gil-Marqués, M. L., Lenhart, T., Hooper, D. C., Kahne, D. E., Losick, R. M., & Bradshaw, N. (2024) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2417323121 · Cited by 16
Ribonucleotide reductase class III, an essential enzyme for the anaerobic growth of Staphylococcus aureus, is a virulence determinant in septic arthritis
Kirdis, E., Jonsson, I., Kubica, M., Potempa, J., Josefsson, E., Masalha, M., Foster, S. J., & Tarkowski, A. (2007) · Microbial Pathogenesis · doi:10.1016/j.micpath.2007.05.008 · Cited by 16
A correlative analysis of epidemiologic and molecular characteristics of methicillin-resistant Staphylococcus aureus clones from diverse geographic locations with virulence measured by a Caenorhabditis elegans host model
Wu, K., Zhang, K., McClure, J., Zhang, J., Schrenzel, J., François, P., Harbarth, S., & Conly, J. M. (2012) · European Journal of Clinical Microbiology & Infectious Diseases · doi:10.1007/s10096-012-1711-x · Cited by 16
Expression of Four Methionine Sulfoxide Reductases in Staphylococcus aureus
Singh, K., & Singh, V. K. (2012) · International Journal of Microbiology · doi:10.1155/2012/719594 · Cited by 16
Glycogen Synthase Kinase 3α Is the Main Isoform That Regulates the Transcription Factors Nuclear Factor-Kappa B and cAMP Response Element Binding in Bovine Endothelial Cells Infected with Staphylococcus aureus
Silva-García, O., Rico-Mata, R., Maldonado-Pichardo, M. C., Bravo-Patiño, A., Valdez-Alarcón, J. J., Aguirre-González, J., & Baizabal-Aguirre, V. M. (2018) · Frontiers in Immunology · doi:10.3389/fimmu.2018.00092 · Cited by 15
Dendritic Cells Internalize Staphylococcus aureus More Efficiently than Staphylococcus epidermidis, but Do Not Differ in Induction of Antigen-Specific T Cell Proliferation
Balraadjsing, P. P. S., de Jong, E. C., van Wamel, W. J. B., & Zaat, S. A. J. (2019) · Microorganisms · doi:10.3390/microorganisms8010019 · Cited by 15
Bacteria-Specific Neutrophil Dysfunction Associated with Interferon-Stimulated Gene Expression in the Acute Respiratory Distress Syndrome
Malcolm, K. C., Kret, J. E., Young, R. L., Poch, K. R., Caceres, S. M., Douglas, I. S., Coldren, C. D., Burnham, E. L., Moss, M., & Nick, J. A. (2011) · PLoS ONE · doi:10.1371/journal.pone.0021958 · Cited by 15
Staphylococcus aureus : a model for bacterial cell biology and pathogenesis
Pinho, M. G., Götz, F., & Peschel, A. (2025) · Journal of Bacteriology · doi:10.1128/jb.00106-25 · Cited by 16
Regulation of Staphylococcus aureus immunodominant antigen B (IsaB)
Mackey-Lawrence, N. M., & Jefferson, K. K. (2012) · Microbiological Research · doi:10.1016/j.micres.2012.07.003 · Cited by 14
Comparative Analysis of Virulence and Toxin Expression of Vancomycin-Intermediate and Vancomycin-Sensitive Staphylococcus aureus Strains
Jin, Y., Yu, X. M., Zhang, S., Kong, X., Chen, W., Luo, Q., Zheng, B., & Xiao, Y. (2020) · Frontiers in Microbiology · doi:10.3389/fmicb.2020.596942 · Cited by 14
Oxidation of bacillithiol during killing ofStaphylococcus aureusUSA300 inside neutrophil phagosomes
Ashby, L. V., Springer, R., Loi, V. V., Antelmann, H., Hampton, M. B., Kettle, A. J., & Dickerhof, N. (2022) · Journal of Leukocyte Biology · doi:10.1002/jlb.4hi1021-538rr · Cited by 13
A comparison of Percutaneous femoral access in Endovascular Repair versus Open femoral access (PiERO): study protocol for a randomized controlled trial
Vierhout, B. P., Saleem, B. R., Ott, A., van Dijl, J. M., de Kempenaer, T. D. V. A., Pierie, M. E., Bottema, J. T., & Zeebregts, C. J. (2015) · Trials · doi:10.1186/s13063-015-0911-y · Cited by 13
Real-time rheology of actively growing bacteria
Portela, R., Almeida, P. L., Patrício, P., Cidade, M. T., Sobral, R. G., & Leal, C. R. (2013) · Physical Review E · doi:10.1103/physreve.87.030701 · Cited by 13
DEVELOPMENT OF SANITARY NAPKIN BY FLAX CARDING WASTE AS ABSORBENT CORE WITH HERBAL AND ANTIMICROBIAL EFFICIENCY
Mishra, S., Pandey, R. K., & Singh, M. (2016) · Cited by 13
Mixed species biofilms of Fusobacterium necrophorum and Porphyromonas levii impair the oxidative response of bovine neutrophils in vitro
Lockhart, J., Buret, A. G., Ceri, H., Storey, D. G., Anderson, S. J., & Morck, D. W. (2017) · Anaerobe · doi:10.1016/j.anaerobe.2017.05.008 · Cited by 13
Granulocytic Phagocytes
Nauseef, W. M., & Clark, R. A. (2010) · Elsevier eBooks · doi:10.1016/b978-0-443-06839-3.00008-4 · Cited by 13
Staphylococcus aureus COL : An Atypical Model Strain of MRSA That Exhibits Slow Growth and Antibiotic Tolerance due to a Mutation in PRPP Synthetase
Stevens, C. E., Deventer, A. T., Johnston, P. R., Lowe, P. T., Boraston, A. B., & Hobbs, J. K. (2025) · Molecular Microbiology · doi:10.1111/mmi.70000 · Cited by 12
Microbiome-Independent Effects of Antibiotics in a Murine Model of Nosocomial Infections
Lacey, K. A., González, S. M., Yeung, F., Putzel, G., Podkowik, M. M., Pironti, A., Shopsin, B., Cadwell, K., & Torres, V. J. (2022) · mBio · doi:10.1128/mbio.01240-22 · Cited by 12
Relationship between virulence factor genes in bovineStaphylococcus aureussubclinical mastitis isolates and binding to anti-adhesin antibodies
Scarpa, M., Piccinini, R., Brun, P., Grillo, A. R., Palù, G., Mengoli, C., Daprà, V., Castagliuolo, I., & Zecconi, A. (2009) · Journal of Dairy Research · doi:10.1017/s0022029909990598 · Cited by 12
Aspartic Acid Residue 51 of SaeR Is Essential for Staphylococcus aureus Virulence
Nygaard, T. K., Borgogna, T. R., Sward, E. W., Guerra, F. E., Dankoff, J. G., Collins, M. M., Pallister, K. B., Chen, L., Kreiswirth, B. N., & Voyich, J. M. (2018) · Frontiers in Microbiology · doi:10.3389/fmicb.2018.03085 · Cited by 12
Self-citation
Pathogenesis and Antibiotic Resistance of Staphylococcus aureus
Kumar, S., Singh, S., Kumar, V., Datta, S., Dhanjal, D. S., Sharma, P., & Singh, J. (2020) · Springer eBooks · doi:10.1007/978-981-15-1695-5_7 · Cited by 12
Bacteriophage infection drives loss of β-lactam resistance in methicillin-resistant Staphylococcus aureusPreprint
Tran, M., Viera, A. J. H., Tran, P. Q., Nilsen, E. D., Tran, L. H., & Mo, C. Y. (2024) · eLife · doi:10.7554/elife.102743 · Cited by 12
Toward Optimization of a Rabbit Model of Staphylococcus aureus (USA300) Skin and Soft Tissue Infection
Małachowa, N., McGuinness, W., Kobayashi, S. D., Porter, A. R., Shaia, C., Lovaglio, J., Smith, B. J., Rungelrath, V., Saturday, G. A., Scott, D. P., et al. (2022) · Microbiology Spectrum · doi:10.1128/spectrum.02716-21 · Cited by 11
Self-citation
Elucidating granulocytic myeloid-derived suppressor cell heterogeneity during Staphylococcus aureus biofilm infection
Bertrand, B. P., Heim, C. E., Koepsell, S. A., & Kielian, T. (2023) · Journal of Leukocyte Biology · doi:10.1093/jleuko/qiad158 · Cited by 11
Differential Effects of Lipid Bilayers on αPSM Peptide Functional Amyloid Formation
Kristoffersen, K., Hansen, K. H., & Andreasen, M. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms25010102 · Cited by 11
In response to bacteria, neutrophils release extracellular vesicles capable of initiating thrombin generation through DNA-dependent and independent pathways
Whitefoot-Keliin, K. M., Benaske, C. C., Allen, E. R., Guerrero, M. T., Grapentine, J. W., Schiff, B., Mahon, A. R., & Greenlee‐Wacker, M. C. (2024) · Journal of Leukocyte Biology · doi:10.1093/jleuko/qiae125 · Cited by 11
The impact of TiO2 nanoparticle exposure on transmembrane cholesterol transport and enhanced bacterial infectivity in HeLa cells
Yang, F., Liu, S., Xu, Y. S., Walker, S. G., Cho, W., Mironava, T., & Rafailovich, M. H. (2021) · Acta Biomaterialia · doi:10.1016/j.actbio.2021.08.012 · Cited by 11
New approaches for functional genomic studies in staphylococci
Beaume, M. G., Hernández, D., François, P., & Schrenzel, J. (2009) · International Journal of Medical Microbiology · doi:10.1016/j.ijmm.2009.11.001 · Cited by 11
Selective recovery of RNAs from bacterial pathogens after their internalization by human host cells
Raynaud, S., Pabic, H. L., & Felden, B. (2018) · Methods · doi:10.1016/j.ymeth.2018.04.035 · Cited by 11
The Response of nor and nos Contributes to Staphylococcus aureus Virulence and Metabolism
Favazzo, L. J., Gill, A. L., Farnsworth, C. W., Mooney, R. A., & Gill, S. R. (2019) · Journal of Bacteriology · doi:10.1128/jb.00107-19 · Cited by 11
What Happens in the Staphylococcal Nucleoid under Oxidative Stress?
Morikawa, K., Ushijima, Y., Ohniwa, R. L., Miyakoshi, M., & Takeyasu, K. (2019) · Microorganisms · doi:10.3390/microorganisms7120631 · Cited by 11
Bacterial superantigens and superantigen-like toxins
Langley, R. J., Fraser, J. D., & Proft, T. (2015) · Elsevier eBooks · doi:10.1016/b978-0-12-800188-2.00032-x · Cited by 11
Diagnosis and management of community-associated MRSA infections in children
Long, C. B., Madan, R. P., & Herold, B. C. (2010) · Expert Review of Anti-infective Therapy · doi:10.1586/eri.09.127 · Cited by 11
Granulocytic Phagocytes
DeLeo, F. R., & Nauseef, W. M. (2015) · Elsevier eBooks · doi:10.1016/b978-1-4557-4801-3.00008-4 · Cited by 11
Self-citation
Microbiota and metabolic adaptation shape Staphylococcus aureus virulence and antimicrobial resistance during intestinal colonizationPreprint
Zhou, C., Pawline, M. B., Pironti, A., Morales, S. M., Perault, A. I., Ulrich, R. J., Podkowik, M. M., Lejeune, A., Dumont, A., Stubbe, F., et al. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.05.11.593044 · Cited by 11
Metabolic diversity of human macrophages: potential influence on Staphylococcus aureus intracellular survival
Bertrand, B. P., Shinde, D. D., Thomas, V. C., Whiteley, M., Ibberson, C. B., & Kielian, T. (2024) · Infection and Immunity · doi:10.1128/iai.00474-23 · Cited by 10
The SaeR/S two-component system induces interferon-gamma production in neutrophils during invasive Staphylococcus aureus infection
Watkins, R. L., Zurek, O. W., Pallister, K. B., & Voyich, J. M. (2013) · Microbes and Infection · doi:10.1016/j.micinf.2013.05.004 · Cited by 10
Self-citation

Authors: Voyich, J. M., Braughton, K. R., Sturdevant, D. E., Whitney, A. R., Saïd-Salim, B., Porcella, S. F., Long, R. D., Dorward, D. W., Gardner, D. J., Kreiswirth, B. N., Musser, J. M., & DeLeo, F. R.
Affiliations: National Institutes of Health (US)
Public Health Research Institute Tuberculosis Center, International Center for Public Health , Newark, NJ 07103
International Center for Public Health (US)
Baylor College of Medicine (US)
ORCID: Voyich, Jovanka M
Porcella, Stephen F
Dorward, David W
Kreiswirth, Barry N
Musser, James M
DeLeo, Frank R
Venue: The Journal of Immunology
Publisher: Oxford University Press (OUP)
Published: 2005-09
Volume: 175
Issue: 6
Pages: 3907-3919
ISSN: 0022-1767 (ISSN-L)
1550-6606
DOI: 10.4049/jimmunol.175.6.3907
OpenAlex: W1848320945
Cited by: 563
References: 58
Citations by year: 2026: 5 · 2025: 17 · 2024: 25 · 2023: 10 · 2022: 20 · 2021: 16 · 2020: 17 · 2019: 23 · 2018: 29 · 2017: 34 · 2016: 29 · 2015: 31 · 2014: 33 · 2013: 49 · 2012: 43
FWCI: 12.79
Type: journal article
Language: en
Open access: closed
Licence: academic.oup.com/pages/standard-publication-reuse-rights (vor)
Locations: The Journal of Immunology (publishedVersion)
PubMed (publishedVersion)
Funders: National Institutes of Health
Topics: Health Sciences › Medicine › Infectious Diseases › Antimicrobial Resistance in Staphylococcus
Life Sciences › Immunology and Microbiology › Immunology › Neutrophil, Myeloperoxidase and Oxidative Mechanisms
Health Sciences › Medicine › Infectious Diseases › Streptococcal Infections and Treatments
Keywords: Staphylococcus aureus, polymorphonuclear leukocytes, innate immunity, phagocytosis, community-acquired infections, nosocomial infections, virulence, capsule synthesis, oxidative stress, gene expression response, virulence factors, methicillin-resistant Staphylococcus aureus, host-pathogen interaction
MeSH terms: Genes, Bacterial, Humans, Immunity, Innate, Neutrophils, Phagocytosis, Staphylococcal Infections, Staphylococcus aureus, Gene Expression Regulation, Bacterial, Gene Expression Profiling, Virulence Factors

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Insights into Mechanisms Used by Staphylococcus aureus to Avoid Destruction by Human Neutrophils

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks