The DOI matches its Crossref record; 63 of the 63 references it cites were found in a registry or an index.
Drosophila Hemopoiesis and Cellular Immunity
Abstract
In Drosophila melanogaster larvae, three classes of circulating cellular immune surveillance cells (hemocytes) can be identified: plasmatocytes, crystal cells, and lamellocytes. Plasmatocytes are professional phagocytes most similar to the mammalian monocyte/macrophage lineage and make up ∼95% of circulating hemocytes. The other ∼5% of circulating hemocytes consists of crystal cells, which secrete components necessary for the melanization of invading organisms, as well as for wound repair. A third cell type known as lamellocytes are rarely seen in healthy larvae and are involved in the encapsulation of invading pathogens. There are no obvious mammalian counterparts for crystal cells or lamellocytes, and there is no equivalent to the lymphoid lineage in insects. In this review, I will discuss what is currently known about Drosophila hemopoiesis and the cellular immune response and where possible compare it to vertebrate mechanisms.
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Metadata
- Authors
- Williams, M. J.
- Venue
- The Journal of Immunology
- Publisher
- Oxford University Press (OUP)
- Published
- 2007-04
- Volume
- 178
- Issue
- 8
- Pages
- 4711-4716
- ISSN
- 0022-1767 (ISSN-L)
- 1550-6606
- OpenAlex
- W1943818783
- Cited by
- 291
- References
- 63
- FWCI
- 4.61
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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