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Immune Hemolysis: A Simplified Method for the Preparation of EaC′4 with Guinea Pig or with Human Complement
Abstract
Summary: The intermediate product of immune hemolysis EAC′4hu was prepared by a new, simplified and rapid method. This stable reagent can be used to titrate the first component of human and guinea pig complement and after conversion of EAC′4hu to EAC′1a4hu can be used to titrate human or guinea pig C′2. The intermediate product EAC′4gp can also be prepared by this new method. Evidence is presented for the existence of two different kinds of SAC′4 both of which are capable of interaction with C′2 but only one of which can be converted to S*.
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Citations
Cited by
Properdin: binding to C3b and stabilization of the C3b-dependent C3 convertase.
Fearon, D. T., & Austen, K. F. (1975) · The Journal of experimental medicine · doi:10.1084/jem.142.4.856 · Cited by 481
Large scale isolation of functionally active components of the human complement system.
Hammer, C. H., Wirtz, G. H., Renfer, L., Gresham, H. D., & Tack, B. F. (1981) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)69557-8 · Cited by 437
A comparison of the properties of two classes, C4A and C4B, of the human complement component C4
Law, S. K., Dodds, A. W., & Porter, R. R. (1984) · The EMBO Journal · doi:10.1002/j.1460-2075.1984.tb02052.x · Cited by 303
INTERACTIONS OF C-REACTIVE PROTEIN WITH THE COMPLEMENT SYSTEM
Siegel, J., Rent, R., & Gewurz, H. (1974) · The Journal of Experimental Medicine · doi:10.1084/jem.140.3.631 · Cited by 256
Metadata
- Authors
- Borsos, T., & Rapp, H. J.
- Venue
- The Journal of Immunology
- Publisher
- Oxford University Press (OUP)
- Published
- 1967-08-01
- Volume
- 99
- Issue
- 2
- Pages
- 263-268
- ISSN
- 0022-1767 (ISSN-L)
- 1550-6606
- OpenAlex
- W1679018503
- Cited by
- 220
- References
- 0
- FWCI
- 7.79
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Immune Hemolysis: A Simplified Method for the Preparation of EaC′4 with Guinea Pig or with Human Complement. https://app.cochat.ai/papers/10.4049/jimmunol.99.2.263
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- Borsos, T., & Rapp, H. J. (1967). Immune Hemolysis: A Simplified Method for the Preparation of EaC′4 with Guinea Pig or with Human Complement. The Journal of Immunology. https://doi.org/10.4049/jimmunol.99.2.263
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
