CoChat
Sign Up
Cited by 242Infective Endocarditis Diagnosis and ManagementBartonella species infections researchBacterial Identification and Susceptibility Testing

Infective Endocarditis Due to Unusual or Fastidious Microorganisms

Berbari, Elie F., Cockerill, Franklin R., Steckelberg, James M.·1997·Mayo Clinic Proceedings
DOI 10.4065/72.6.532
Open this paper in CoChat — free account

Abstract

Infective endocarditis due to fastidious microorganisms is commonly encountered in clinical practice. Some organisms such as fungi account for up to 15% of cases of prosthetic valve infective endocarditis, whereas organisms of the HACEK group (Haemophilus parainfluenzae, H. aphrophilus, and H. paraphrophilus, Actinobacillus actinomycetemcomitans, Cardiobacterium hominis, Eikenella corrodens, and Kingella kingae) cause 3% of community-acquired cases of infective endocarditis. Special techniques are necessary to identify these microorganisms. A history of contact with mammals or birds may suggest infection caused by Coxiella burnetii (Q fever), Brucella species, or Chlamydia psittaci. A nosocomial cluster of postsurgical infective endocarditis may be caused by Legionella species or Mycobacterium species. If risk factors that are commonly associated with fungal infections (cardiac surgical treatment, prolonged hospitalization, indwelling central venous catheters, and long-term antibiotic use) are present, fungal endocarditis is possible. Patients with endocarditis and a history of periodontal disease or dental work in whom routine blood cultures are negative might have infection due to nutritionally variant streptococci or bacteria of the HACEK group. Communication between the microbiologist and the clinician is of crucial importance for identification of these microorganisms early during the course of the infection before complications such as embolization or valvular failure o…

Integrity signals

Registry

Crossref · 10.4065/72.6.532

Cites

85 of 85 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Cites

Flagged first, then by citations

1 of the 86 references couldn’t be matched to a known paper.

Cited by

Sorted by citations

Related

Authors
Berbari, E. F., Cockerill, F. R., & Steckelberg, J. M.
Affiliations
Mayo Clinic (US)
Corresponding author
Steckelberg, James M.
ORCID
Berbari, Elie F.
Venue
Mayo Clinic Proceedings
Publisher
Elsevier BV
Published
1997-06
Volume
72
Issue
6
Pages
532-542
ISSN
0025-6196 (ISSN-L)
DOI
10.4065/72.6.532
OpenAlex
W2079302241
Cited by
242
References
86
Citations by year
2026: 1 · 2025: 1 · 2024: 2 · 2023: 5 · 2022: 2 · 2021: 4 · 2020: 3 · 2019: 4 · 2018: 7 · 2017: 3 · 2016: 6 · 2015: 14 · 2014: 6 · 2013: 10 · 2012: 7
FWCI
1.39
Type
journal article
Language
en
Open access
closed
Licence
www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations
  • Mayo Clinic Proceedings (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Epidemiology › Infective Endocarditis Diagnosis and Management
  • Life Sciences › Immunology and Microbiology › Parasitology › Bartonella species infections research
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Clinical Biochemistry › Bacterial Identification and Susceptibility Testing
Keywords
infective endocarditis, fastidious microorganisms, HACEK group, fungal endocarditis, prosthetic valve endocarditis, Coxiella burnetii, Brucella, Chlamydia psittaci, Legionella, Mycobacterium, nutritionally variant streptococci, periodontal disease, blood culture, diagnosis, treatment
MeSH terms
Anti-Bacterial Agents, Bartonella Infections, Brucellosis, Corynebacterium Infections, Endocarditis, Endocarditis, Bacterial, Gonorrhea, Humans, Legionellosis, Listeriosis, Mycoses, Q Fever

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review