The DOI matches its Crossref record.
Risk of Suicide Attempts Among Adolescents and Young Adults With Autism Spectrum Disorder: A Nationwide Longitudinal Follow-Up Study
Abstract
BACKGROUND: Previous studies reported a high prevalence of depression among patients with autism spectrum disorder (ASD) and suggested a relationship between ASD and suicidality. However, whether ASD independently increases the risk of attempted suicide regardless of depression has not been determined. METHODS: Using the Taiwan National Health Insurance Research Database, 5,618 adolescents aged 12-17 years and young adults aged 18-29 years with ASD (ICD-9-CM code: 299) and 22,472 age- and sex-matched controls were enrolled between 2001 and 2009 and followed to the end of 2011. Any suicide attempt was identified during the follow-up period. RESULTS: Patients with ASD had a higher incidence of suicide attempts (3.9% vs 0.7%, P < .001) than did those without ASD. Both adolescents (HR = 5.79; 95% CI, 3.98-8.41) and young adults (HR = 5.38; 95% CI, 3.58-8.06) with ASD were more likely to attempt suicide in later life after adjusting for demographic data and psychiatric comorbidities. Sensitivity analyses after excluding the first year (HR = 4.52; 95% CI, 3.39-6.03) or first 3 years (HR = 3.36; 95% CI, 2.40-4.70) of observation showed consistent findings. CONCLUSIONS: Patients with ASD had an increased risk of suicide attempts compared with those without ASD. ASD was an independent risk factor of attempted suicide. Further studies are needed to clarify the underlying pathophysiology between ASD and suicidality and to elucidate whether prompt intervention for ASD may reduce this risk.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“ASC diagnosis has also recently been found to be an independent risk marker for suicide attempts independent of demographic characteristics and co-occurring diagnoses [19].”
From Risk markers for suicidality in autistic adults (2018) · cites this paper as [19]
In the citing paper
“This is consistent with research showing that ASC diagnosis is an independent risk marker for suicide attempts when controlling for a range of demographics and co-occurring diagnoses [19].”
From Risk markers for suicidality in autistic adults (2018) · cites this paper as [19]
Citations
Cites
Still being checked.
Cited by
Sorted by citations
Risk markers for suicidality in autistic adults
Cassidy, S., Bradley, L., Shaw, R., & Baron-Cohen, S. (2018) · Molecular Autism · doi:10.1186/s13229-018-0226-4 · Cited by 621
A 20‐year study of suicide death in a statewide autism population
Kirby, A. V., Bakian, A. V., Zhang, Y., Bilder, D. A., Keeshin, B. R., & Coon, H. (2019) · Autism Research · doi:10.1002/aur.2076 · Cited by 192
Assessment of Suicidal Behaviors Among Individuals With Autism Spectrum Disorder in Denmark
Kõlves, K., Fitzgerald, C., Nordentoft, M., Wood, S. J., & Erlangsen, A. (2021) · JAMA Network Open · doi:10.1001/jamanetworkopen.2020.33565 · Cited by 191
Suicidality in autistic youth: A systematic review and meta-analysis
O'Halloran, L., Coey, P., & Wilson, C. (2022) · Clinical Psychology Review · doi:10.1016/j.cpr.2022.102144 · Cited by 146
Mutluer, T., Genç, H. A., Morey, A. Ö., Eser, H. Y., Ertinmaz, B., CAN, M., & Münir, K. (2022) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2022.856208 · Cited by 162
Metadata
- Authors
- Chen, M.-H., Pan, T.-L., Lan, W.-H., Hsu, J.-W., Huang, K.-L., Su, T.-P., Li, C.-T., Lin, W.-C., Wei, H.-T., Chen, T.-J., & Bai, Y.-M.
- Affiliations
- Taipei Veterans General Hospital (TW)
- Chang Gung University (TW)
- Venue
- The Journal of Clinical Psychiatry
- Publisher
- Physicians Postgraduate Press, Inc
- Published
- 2017-12-27
- Volume
- 78
- Issue
- 9
- Pages
- e1174-e1179
- ISSN
- 0160-6689 (ISSN-L)
- OpenAlex
- W2747034110
- Cited by
- 121
- References
- 0
- Citations by year
- 2026: 8 · 2025: 18 · 2024: 18 · 2023: 13 · 2022: 16 · 2021: 16 · 2020: 15 · 2019: 14 · 2018: 3
- FWCI
- 10.85
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- The Journal of Clinical Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Social Sciences › Psychology › Clinical Psychology › Suicide and Self-Harm Studies
- Life Sciences › Neuroscience › Cognitive Neuroscience › Autism Spectrum Disorder Research
- Health Sciences › Medicine › Psychiatry and Mental health › Child Nutrition and Feeding Issues
- Keywords
- autism spectrum disorder, suicide attempts, suicidality, adolescents, young adults, depression, psychiatric comorbidity, risk factors
- MeSH terms
- Autism Spectrum Disorder, Adolescent, Adult, Child, Follow-Up Studies, Humans, Longitudinal Studies, Risk Factors, Suicide, Attempted, Taiwan, Case-Control Studies, Young Adult
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
