Suicidality in Autistic Spectrum Disorders: A Systematic Review
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Abstract. Background: It is suggested that people with autistic spectrum disorders (ASD) may be at increased risk of suicide; however, research on this topic has been minimal and there are conflicting reports in existing studies. Aim: To bring together research investigating the prevalence, risk factors, and comorbid factors of suicidality in ASD. Method: A systematic search was performed of Medline, Psych Info, Embase, and the Web of Science following PRISMA guidelines. After exclusion criteria were applied, 70 full-text articles were screened. The final review contained 12 papers with a total sample size of 2,651. Results: Prevalence of suicide attempts varied between 7% and 47%, while suicidal ideation was reported in up to 72% of cases. Being male and having a history of self-harm and depression were cited as significant risk factors. Limitations: Papers were cross sectional and contained a number of limitations. Only one paper used the gold standard for diagnosis of ASD and one a standardized measure of suicidal behavior. Conclusion: Suicidal attempts and ideation are increased in ASD; however, the extent of the increase and the risk factors identified within this group remain under-investigated. There is a lack of research on protective factors. The correlation between ASD and suicidality needs further examination with longitudinal research.
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Suicidal ideation and suicidal attempts have been reported at high rates in autistic individuals, with the prevalence of suicidal attempts ranging between 7 and 47%.
“In addition to self-harm, suicidal ideation and suicidal attempts have also been reported at high rates in autistic individuals (Hedley & Uljarević, 2018; Dell'Osso et al., 2019), with the prevalence of suicidal attempts ranging between 7 and 47% (Zahid & Upthegrove, 2017).”
From Feasibility, Acceptability and Preliminary Efficacy of Dialectical Behavior Therapy for Autistic Adults without Intellectual Disability: A Mixed Methods Study (2022) · cites this paper as Zahid & Upthegrove, 2017
There are elevated rates of suicidality in adults diagnosed with ASC.
“There are elevated rates of suicidality in adults diagnosed with autism spectrum conditions (ASC) [1–5].”
From Risk markers for suicidality in autistic adults (2018) · cites this paper as [1]
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- ABC, Autism Behaviour Checklist; ADIS-IV-C/P, Anxiety Disorders Interview Schedule for Children for DSM-IV; ADOS, The Autism Diagnostic Observation Schedule; AQ, Autism Spectrum Quotient questionnaire; AQ-J, Autism Spectrum Quotient-Japanese Version questionnaire; BPRS, Brief Psychiatric Rating Scale; CASD, The Checklist for Autism Spectrum Disorder; CBLC, The Child Behaviour Checklist; CGI, Clinical global impression; CIS-PV, Columbia Impairment Scale-Parent Version; DSM-III-R, Diagnostic and Statistical Manual of Mental Disorders-Third Edition-Revised; DSM-IV-TR, Diagnostic and Statistical Manual of Mental Disorders-Fourth Edition, text revision; GAF, Global assessment of functioning; JART, Japanese Version Adult Reading Test; KADI, Krug Asperger's Disorder Index, K-SADS, Kiddie Schedule for Affective Disorders and Schizophrenia for School-Age Children--Present and Lifetime; MASC-P, Multidimensional Anxiety Scale for Children-Parent; MDS-UPDRS, Unified Parkinson's Disease Rating Scale; MINI, Mini International Neuropsychiatric Interview ; MMSE, Mini-Mental State Examination; PARS, The Paediatric Anxiety Rating Scale; PBS, Paediatric Behaviour Scale; PHQ-A, Patient Health Questionnaire for Adolescents; SANS, Scale for the Assessment of Negative Symptoms; SAPS, Scale for the Assessment of Positive Symptoms; SIQ, Suicidal Ideation Questionnaire; SQID-II, The Structured Clinical Interview for DSM-IV Axis II Personality Disorders; WAIS-R, Wechsler Adult Intelligence Scale-Revised;
- WISC-R, Wechsler Intelligence Scale for Children-Revised; WISC-III, Wechsler Intelligence Scale for Children-Third Edition; WISC-IV, Wechsler Intelligence Scale for Children- Fourth Edition 2.3 Typical N=186, (43.5% Males) Mean age 8.7, SD, 1.7
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- Authors
- Zahid, S., & Upthegrove, R.
- Affiliations
- University of Birmingham (GB)
- ORCID
- Upthegrove, Rachel
- Venue
- Crisis
- Publisher
- Hogrefe Publishing Group
- Published
- 2017-07
- Volume
- 38
- Issue
- 4
- Pages
- 237-246
- ISSN
- 0227-5910 (ISSN-L)
- 2151-2396
- OpenAlex
- W2610605440
- Cited by
- 115
- References
- 31
- Citations by year
- 2026: 6 · 2025: 13 · 2024: 13 · 2023: 10 · 2022: 16 · 2021: 23 · 2020: 15 · 2019: 13 · 2018: 5 · 2017: 1
- FWCI
- 1.43
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Crisis (publishedVersion)
- PubMed (publishedVersion)
- University of Birmingham Research Portal (University of Birmingham) (submittedVersion, other-oa)
- Topics
- Social Sciences › Psychology › Clinical Psychology › Suicide and Self-Harm Studies
- Life Sciences › Neuroscience › Cognitive Neuroscience › Autism Spectrum Disorder Research
- Social Sciences › Sociology and Political Science › Homicide, Infanticide, and Child Abuse
- Keywords
- suicidality, autism spectrum disorder, suicide attempts, suicidal ideation, risk factors, self-harm, depression, prevalence, comorbidities, protective factors
- MeSH terms
- Autism Spectrum Disorder, Anxiety Disorders, Depressive Disorder, Humans, Risk Factors, Suicide, Suicide, Attempted, Comorbidity, Prevalence, Attention Deficit and Disruptive Behavior Disorders, Suicidal Ideation
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