IPS multicentric study: Antidepressant prescription patterns
Open accessAbstract
BACKGROUND: There are very few studies from India which have evaluated the prescription pattern for antidepressants by psychiatrists for treatment of depression. AIM: To study the psychotropic prescription patterns of patients with first episode depression from diverse settings including teaching institutions in public and private sectors and even privately run psychiatric clinics. MATERIALS AND METHODS: Prescription data of 706 patients with first episode depression, who participated in the IPS multicentric study, were evaluated. RESULTS: Escitalopram was the most commonly prescribed antidepressant, comprising 40% of the total prescriptions. This was followed by sertraline (17.6%) and fluoxetine (16.3%). In total, selective serotonin reuptake inhibitors (SSRIs) formed 79.2% of all the prescriptions. Tricyclic antidepressants formed a small part (15.15%) of total prescriptions, with imipramine being the most commonly used tricyclic antidepressant. Serotonin-norepinephrine reuptake inhibitors (venlafaxine, desvenlafaxine and duloxetine) were prescribed to 11.3% of patients with equal share of venlafaxine and duloxetine. About one-sixth (N=104; 14.7%) of the patients were prescribed more than one antidepressant. Nearly three-fourth of the patients (N=523; 74.1%) were prescribed a benzodiazepine, with clonazepam being the most preferred agent, prescribed to nearly half of the participants (49%) and formed nearly two-third of the total benzodiazepine prescriptions (346 out of 523). CONCLUSION: Escitalopram is the most commonly prescribed antidepressant and SSRIs are the most commonly prescribed class of antidepressants. Poly pharmacy in the form of concomitant use of two antidepressants is practiced infrequently. However, benzodiazepines are used quite frequently as the co-prescription.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In Asia, SSRIs dominated in almost every country, but particular prescription preferences differed from country to country.
“In Asia, though SSRIs dominated in almost every country, the particular prescription preferences were different from country to country (35–37).”
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
An inventory for measuring depression
BECK, A. T. (1961) · Archives of General Psychiatry · doi:10.1001/archpsyc.1961.01710120031004 · Cited by 38,032 · see citing works
Lecrubier, Y., Sheehan, D., Weiller, E., Amorim, P., Bonora, I., Sheehan, K. H., Janavs, J., & Dunbar, G. (1997) · European Psychiatry · doi:10.1016/s0924-9338(97)83296-8 · Cited by 3,513 · see citing works
The American Psychiatric Association (APA)
Strentz, T. (2017) · CRC Press eBooks · doi:10.1201/9781315150581-3 · Cited by 1,855 · see citing works
PRACTICE GUIDELINE FOR THE Treatment of Patients With Major Depressive Disorder
Gelenberg, A. J., Freeman, P. B., Markowitz, J. C., Rosenbaum, J. F., Thase, M. E., Trivedi, M. H., & Rhoads, R. S. (2010) · Cited by 1,372 · see citing works
Amorim, P., Lecrubier, Y., Weiller, E., Hergueta, T., & Sheehan, D. V. (1998) · European Psychiatry · doi:10.1016/s0924-9338(97)86748-x · Cited by 318 · see citing works
Bauer, M., Monz, B. U., Montejo, A. L., Quail, D., Dantchev, N., Demyttenaere, K., Garcia-Cebrian, A., Grassi, L., Perahia, D. G. S., Reed, C., et al. (2008) · European Psychiatry · doi:10.1016/j.eurpsy.2007.11.001 · Cited by 186 · see citing works
An audit of first prescription of new patients attending a psychiatry walk-in-clinic in north India
Grover, S., Kumar, V., Avasthi, A., & Kulhara, P. (2012) · Indian Journal of Pharmacology · doi:10.4103/0253-7613.96302 · Cited by 58 · see citing works
Self-citationUCHIDA, N., CHONG, M., TAN, C. H., NAGAI, H., TANAKA, M., LEE, M., FUJII, S., YANG, S., SI, T., SIM, K., et al. (2007) · Psychiatry and Clinical Neurosciences · doi:10.1111/j.1440-1819.2007.01702.x · Cited by 56 · see citing works
Lako, I. M., Taxis, K., Bruggeman, R., Knegtering, H., Burger, H., Wiersma, D., & Slooff, C. J. (2011) · European Psychiatry · doi:10.1016/j.eurpsy.2010.10.007 · Cited by 54 · see citing works
Kjosavik, S. R., Hunskaar, S., Aarsland, D., & Ruths, S. (2011) · Acta Psychiatrica Scandinavica · doi:10.1111/j.1600-0447.2011.01697.x · Cited by 36 · see citing works
Nakao, M., Takeuchi, T., & Yano, E. (2007) · International Journal of Clinical Pharmacology and Therapeutics · doi:10.5414/cpp45030 · Cited by 30 · see citing works
Trivedi, J. K., Dhyani, M., Sareen, H., et al. (2010) · Medical Practice and Reviews · doi:10.5897/mpr.9000003 · Cited by 16 · see citing works
Patterns of antidepressant prescriptions : I acute phase treatments.
Chakrabarti, S., & Kulhara, P. (2000) · PubMed · Cited by 9 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
Luo, Y., Kataoka, Y., Ostinelli, E. G., Cipriani, A., & Furukawa, T. A. (2020) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2020.00035 · Cited by 206 · see citing works
- Authors
- Grover, S., Avasth, A., Kalita, K., Dalal, P., Rao, G., Chadda, R., Lakdawala, B., Bang, G., Chakraborty, K., Kumar, S., Singh, P., Kathuria, P., Thirunavukarasu, M., Sharma, P. S. V. N., Harish, T., Shah, N., & Deka, K.
- Affiliations
- Post Graduate Institute of Medical Education and Research (IN)
- Corresponding author
- Grover, Sandeep
- Venue
- Indian Journal of Psychiatry
- Published
- 2013
- Volume
- 55
- Issue
- 1
- Pages
- 41
- ISSN
- 0019-5545 (ISSN-L)
- PMC
- PMC3574454
- OpenAlex
- W2067018628
- Cited by
- 53
- References
- 13
- Citations by year
- 2025: 3 · 2024: 2 · 2023: 4 · 2022: 2 · 2021: 4 · 2020: 3 · 2019: 4 · 2018: 3 · 2017: 6 · 2016: 5 · 2015: 11 · 2014: 6
- FWCI
- 5.38
- Type
- journal article
- Language
- en
- Open access
- diamond
- doi.org
- Licence
- cc-by-nc-sa
- Locations
- Indian Journal of Psychiatry (publishedVersion, cc-by-nc-sa)
- Europe PMC (PubMed Central) (publishedVersion, cc-by-nc-sa)
- PubMed Central (publishedVersion, cc-by-nc-sa)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Pharmacology › Treatment of Major Depression
- Social Sciences › Psychology › Social Psychology › Mental Health Treatment and Access
- Social Sciences › Psychology › Clinical Psychology › Psychological Treatments and Disorders
- Keywords
- first-episode depression, selective serotonin reuptake inhibitors, escitalopram, sertraline, fluoxetine, tricyclic antidepressants, imipramine, serotonin-norepinephrine reuptake inhibitors, venlafaxine, duloxetine, desvenlafaxine, benzodiazepines, clonazepam, polypharmacy, co-prescription, India
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
