Parkinson's disease, depression, and quality-of-life
Open accessAbstract
BACKGROUND: Depression is the most common psychiatric disorder associated with Parkinson's disease (PD) but is often under diagnosed and under treated leading to worsening of symptoms and deterioration of the quality-of-life of the people suffering from this disease. AIMS: The current study aims to determine the correlation between depression and health-related quality-of-life (HRQOL) domains in patients with PD. MATERIALS AND METHODS: A sample of 65 consecutive patients attending the specialty Parkinson's clinic was assessed by a psychiatrist as part of the treatment protocol. Diagnosis of depression was done using the International Classification of Diseases-10 by a psychiatrist and depression was scored using the Geriatric Depression Scale (GDS). QOL-BREF Malayalam version was used to assess quality-of-life in the patients. STATISTICAL ANALYSIS: One-way ANOVA was used to find the difference in the quality-of-life experienced by different age categories, duration of the disease, psychiatric co-morbidity. Independent sample t-test was used to find the difference in the quality-of-life experienced by genders, co morbid conditions and to find the difference in the scores on GDS and domains of WHO QOL BREF. Association of H and Y staging and duration of Parkinsonism with GDS Scores were computed using Pearson's Chi-square test. RESULTS AND CONCLUSIONS: There was a significant association of female gender and depression with the physical and psychological domains of QOL while the duration and staging of PD did not have any association with QOL Domains. Depression thus emerges as one of the main predictors of poor quality-of-life in PD.
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Anxiety and depression are thought to be the strongest PD quality of life predictors.
“are thought to be the strongest PD quality of life predictors (Rahman et al., 2008”
From Remote delivery of psychological interventions for Parkinson's disease. (2018) · cites this paper as Menon et al., 2015
The Discussion identifies depression as the most important predictor of poor quality of life in this study. It also states that psychiatric conditions other than depression were not considered, so the paper does not establish anxiety as one of the strongest predictors. (LLM, conf=0.90)
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ДЕПРЕССИЯ ПРИ БОЛЕЗНИ ПАРКИНСОНА: ОПРЕДЕЛЯЮЩАЯ РОЛЬ СТАДИИ И МОТОРНОГО ДЕФИЦИТА
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“Опубліковані суперечливі дані щодо відмінності цих параметрів у пацієнтів на різних стадіях ХП, а також наявності кореляційних зв’язків між цими показниками та результатами оцінювання когнітивних функцій за відповідними шкалами [8].”
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BackgroundA study on modeling the dopaminergic pathways of Parkinson’s disease
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Chronic pain and psychological distress among adults in Udupi
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Background
- Authors
- Menon, B., Nayar, R., Kumar, S., Cherkil, S., Venkatachalam, A., Surendran, K., & Deepak, K. S.
- Affiliations
- Amrita Institute of Medical Sciences and Research Centre (IN)
- Corresponding author
- Menon, Bindu
- Venue
- Indian Journal of Psychological Medicine
- Publisher
- SAGE Publications
- Published
- 2015-04
- Volume
- 37
- Issue
- 2
- Pages
- 144-148
- ISSN
- 0253-7176 (ISSN-L)
- 0975-1564
- PMC
- PMC4418244
- OpenAlex
- W1973735980
- Cited by
- 57
- References
- 34
- Citations by year
- 2026: 8 · 2025: 2 · 2024: 5 · 2023: 5 · 2022: 7 · 2021: 7 · 2020: 8 · 2019: 4 · 2018: 3 · 2017: 2 · 2016: 4 · 2015: 2
- FWCI
- 2.59
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Licence
- Locations
- Indian Journal of Psychological Medicine (publishedVersion)
- Europe PMC (PubMed Central) (publishedVersion, cc-by-nc-sa)
- PubMed Central (publishedVersion, cc-by-nc-sa)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Topics
- Health Sciences › Medicine › Neurology › Parkinson's Disease Mechanisms and Treatments
- Health Sciences › Medicine › Neurology › Neurological disorders and treatments
- Social Sciences › Psychology › Clinical Psychology › Health and Well-being Studies
- Keywords
- Parkinson's disease, depression, health-related quality of life, Geriatric Depression Scale, WHOQOL-BREF, psychiatric comorbidity, disease duration, disease staging, sex differences, Malayalam
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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