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Cited by 158Alcoholism and Thiamine DeficiencySubstance Abuse Treatment and OutcomesAlcohol Consumption and Health Effects

The DOI matches its Crossref record; 49 of the 49 references it cites were found in a registry or an index.

Clinical management of alcohol withdrawal: A systematic review

Open access
Bharadwaj, Balaji, Kattimani, Shivanand·2013·Industrial Psychiatry Journal
DOI 10.4103/0972-6748.132914PMC PMC4085800
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Abstract

Alcohol withdrawal is commonly encountered in general hospital settings. It forms a major part of referrals received by a consultation-liaison psychiatrist. This article aims to review the evidence base for appropriate clinical management of the alcohol withdrawal syndrome. We searched Pubmed for articles published in English on pharmacological management of alcohol withdrawal in humans with no limit on the date of publication. Articles not relevant to clinical management were excluded based on the titles and abstract available. Full-text articles were obtained from this list and the cross-references. There were four meta-analyses, 9 systematic reviews, 26 review articles and other type of publications like textbooks. Alcohol withdrawal syndrome is a clinical diagnosis. It may vary in severity. Complicated alcohol withdrawal presents with hallucinations, seizures or delirium tremens. Benzodiazepines have the best evidence base in the treatment of alcohol withdrawal, followed by anticonvulsants. Clinical institutes withdrawal assessment-alcohol revised is useful with pitfalls in patients with medical comorbidities. Evidence favors an approach of symptom-monitored loading for severe withdrawals where an initial dose is guided by risk factors for complicated withdrawals and further dosing may be guided by withdrawal severity. Supportive care and use of vitamins is also discussed.

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Crossref · 10.4103/0972-6748.132914

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Figures

Figure 1 Neurochemistry of alcohol withdrawal
Figure 1 Neurochemistry of alcohol withdrawalCC BY-NC-SA · PubMed Central
Figure 2 Graph depicting the time course of alcohol withdrawal symptoms (based on clinical information gathered in Table 2; adaptation from Haber et al.[7])
Figure 2 Graph depicting the time course of alcohol withdrawal symptoms (based on clinical information gathered in Table 2; adaptation from Haber et al.[7])CC BY-NC-SA · PubMed Central

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Cites

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Research works printed but not linked: 2

  1. Tovar, 2011, Diagnosis and treatment of alcohol withdrawal, J Clin Outcomes Manag, 361
  2. Dubovsky SL. Benzodiazepine receptor agonists and antagonists. In: Sadock BJ, Virginia A, Ruiz P, editors. Kaplan and Sadock′s Comprehensive Textbook of Psychiatry. 9 th ed. Philadelphia: Lippincott Williams and Wilkins; 2009.

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Metadata

Authors
Bharadwaj, B., & Kattimani, S.
Affiliations
Jawaharlal Institute of Post Graduate Medical Education and Research (IN)
Corresponding author
Bharadwaj, Balaji
ORCID
Venue
Industrial Psychiatry Journal
Publisher
Ovid Technologies (Wolters Kluwer Health)
Published
2013
Volume
22
Issue
2
Pages
100
ISSN
0972-6748 (ISSN-L)
DOI
10.4103/0972-6748.132914
PMC
PMC4085800
OpenAlex
W2059915772
Cited by
154
References
49
Citations by year
2026: 10 · 2025: 15 · 2024: 16 · 2023: 24 · 2022: 16 · 2021: 12 · 2020: 17 · 2019: 10 · 2018: 6 · 2017: 12 · 2016: 7 · 2015: 8 · 2014: 1
FWCI
0.70
Type
journal article
Language
en
Open access
Licence
cc-by-nc-sa
Locations
  • Industrial Psychiatry Journal (publishedVersion, cc-by-nc-sa)
  • PubMed Central (publishedVersion, cc-by-nc-sa)
  • PubMed (publishedVersion)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
Topics
  • Health Sciences › Medicine › Clinical Neurology › Alcoholism and Thiamine Deficiency
  • Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
  • Health Sciences › Medicine › Pathology and Forensic Medicine › Alcohol Consumption and Health Effects
Keywords
alcohol withdrawal, benzodiazepines, antiepileptic drugs, delirium tremens, hallucinations, CAGE questionnaire, supportive care, vitamins, psychosomatic medicine

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