The DOI matches its Crossref record; 109 of the 109 references it cites were found in a registry or an index.
A systematic review and meta-analysis to determine the effect of sperm DNA damage on in vitro fertilization and intracytoplasmic sperm injection outcome
Open accessAbstract
Sperm DNA damage is prevalent among infertile men and is known to influence natural reproduction. However, the impact of sperm DNA damage on assisted reproduction outcomes remains controversial. Here, we conducted a meta-analysis of studies on sperm DNA damage (assessed by SCSA, TUNEL, SCD, or Comet assay) and clinical pregnancy after IVF and/or ICSI treatment from MEDLINE, EMBASE, and PUBMED database searches for this analysis. We identified 41 articles (with a total of 56 studies) including 16 IVF studies, 24 ICSI studies, and 16 mixed (IVF + ICSI) studies. These studies measured DNA damage (by one of four assays: 23 SCSA, 18 TUNEL, 8 SCD, and 7 Comet) and included a total of 8068 treatment cycles (3734 IVF, 2282 ICSI, and 2052 mixed IVF + ICSI). The combined OR of 1.68 (95% CI: 1.49-1.89; P < 0.0001) indicates that sperm DNA damage affects clinical pregnancy following IVF and/or ICSI treatment. In addition, the combined OR estimates of IVF (16 estimates, OR = 1.65; 95% CI: 1.34-2.04; P < 0.0001), ICSI (24 estimates, OR = 1.31; 95% CI: 1.08-1.59; P = 0.0068), and mixed IVF + ICSI studies (16 estimates, OR = 2.37; 95% CI: 1.89-2.97; P < 0.0001) were also statistically significant. There is sufficient evidence in the existing literature suggesting that sperm DNA damage has a negative effect on clinical pregnancy following IVF and/or ICSI treatment.
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Cites
Microelectrophoretic study of radiation-induced DNA damages in individual mammalian cells
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Systematic Reviews in Health Care. Meta-analysis in Context.
Kleijnen, J., & Antes, G. (2002) · International Journal of Epidemiology · doi:10.1093/ije/31.3.697 · Cited by 1,363
Evenson, D. P. (1999) · Human Reproduction · doi:10.1093/humrep/14.4.1039 · Cited by 1,121
Gorczyca, W., GONG, J., & Darżynkiewicz, Z. (1993) · PubMed · Cited by 982
Conducting systematic reviews of diagnostic studies: didactic guidelines
Devillé, W. L., Buntinx, F., Bouter, L. M., Montori, V. M., de Vet, H. C., van der Windt, D. A., & Bezemer, P. D. (2002) · BMC Medical Research Methodology · doi:10.1186/1471-2288-2-9 · Cited by 960
Sun, J.-G., Jurisicova, A., & Casper, R. F. (1997) · Biology of Reproduction · doi:10.1095/biolreprod56.3.602 · Cited by 753
Sperm DNA integrity assessment in prediction of assisted reproduction technology outcome
Bungum, M., Humaidan, P., Axmon, A., Spano, M., Bungum, L., Erenpreiss, J., & Giwercman, A. (2007) · Human Reproduction · doi:10.1093/humrep/del326 · Cited by 703
Fernández, J. L., Muriel, L., Rivero, M. T., Goyanes, V., Vazquez, R., & Alvarez, J. G. (2003) · Journal of Andrology · doi:10.1002/j.1939-4640.2003.tb02641.x · Cited by 650
Virro, M. R., Larson-Cook, K. L., & Evenson, D. P. (2004) · Fertility and Sterility · doi:10.1016/j.fertnstert.2003.09.063 · Cited by 601
Zini, A., Boman, J. M., Belzile, E., & Ciampi, A. (2008) · Human Reproduction · doi:10.1093/humrep/den321 · Cited by 576
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Cited by
Schisterman, E. F., Sjaarda, L. A., Clemons, T., Carrell, D. T., Perkins, N. J., Johnstone, E., Lamb, D., Chaney, K., Van Voorhis, B. J., Ryan, G., et al. (2020) · JAMA · doi:10.1001/jama.2019.18714 · Cited by 179
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Metadata
- Authors
- Carrell, D., Simon, L., Zini, A., Dyachenko, A., & Ciampi, A.
- Venue
- Asian Journal of Andrology
- Published
- 2017
- Volume
- 19
- Issue
- 1
- Pages
- 80
- ISSN
- 1008-682X (ISSN-L)
- OpenAlex
- W2484933983
- Cited by
- 409
- References
- 109
- FWCI
- 45.70
- Type
- journal article
- Language
- en
- Open access
- gold
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- Carrell, D., Simon, L., Zini, A., Dyachenko, A., & Ciampi, A. (2017). A systematic review and meta-analysis to determine the effect of sperm DNA damage on in vitro fertilization and intracytoplasmic sperm injection outcome. Asian Journal of Andrology. https://doi.org/10.4103/1008-682x.182822
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
