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Cited by 403

The DOI matches its Crossref record; 120 of the 120 references it cites were found in a registry or an index.

Introduction to Digital Image Analysis in Whole-slide Imaging: A White Paper from the Digital Pathology Association

Open access
Aeffner, Famke, Zarella, Mark D., Buchbinder, Nathan, Bui, Marilyn M., Goodman, Matthew R., Hartman, Douglas J., Lujan, Giovanni M., Molani, Mariam A., Parwani, Anil V., Lillard, Kate, Turner, Oliver C., Vemuri, Venkata N.P., Yuil-Valdes, Ana G., Bowman, Douglas·2019·Journal of Pathology Informatics

Abstract

The advent of whole-slide imaging in digital pathology has brought about the advancement of computer-aided examination of tissue via digital image analysis. Digitized slides can now be easily annotated and analyzed via a variety of algorithms. This study reviews the fundamentals of tissue image analysis and aims to provide pathologists with basic information regarding the features, applications, and general workflow of these new tools. The review gives an overview of the basic categories of software solutions available, potential analysis strategies, technical considerations, and general algorithm readouts. Advantages and limitations of tissue image analysis are discussed, and emerging concepts, such as artificial intelligence and machine learning, are introduced. Finally, examples of how digital image analysis tools are currently being used in diagnostic laboratories, translational research, and drug development are discussed.

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Metadata

Authors
Aeffner, F., Zarella, M. D., Buchbinder, N., Bui, M. M., Goodman, M. R., Hartman, D. J., Lujan, G. M., Molani, M. A., Parwani, A. V., Lillard, K., Turner, O. C., Vemuri, V. N. P., Yuil-Valdes, A. G., & Bowman, D.
Venue
Journal of Pathology Informatics
Publisher
Elsevier BV
Published
2019-01
Volume
10
Issue
1
Pages
9
ISSN
2153-3539 (ISSN-L)
OpenAlex
W2921675148
Cited by
403
References
120
FWCI
22.10
Type
journal article
Language
en
Open access
gold

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CoChat. (2026). Citation check: Introduction to Digital Image Analysis in Whole-slide Imaging: A White Paper from the Digital Pathology Association. https://app.cochat.ai/papers/10.4103/jpi.jpi_82_18
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Aeffner, F., Zarella, M. D., Buchbinder, N., Bui, M. M., Goodman, M. R., Hartman, D. J., Lujan, G. M., Molani, M. A., Parwani, A. V., Lillard, K., Turner, O. C., Vemuri, V. N. P., Yuil-Valdes, A. G., & Bowman, D. (2019). Introduction to Digital Image Analysis in Whole-slide Imaging: A White Paper from the Digital Pathology Association. Journal of Pathology Informatics. https://doi.org/10.4103/jpi.jpi_82_18

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.