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Evaluating the efficacy of mixture of Boswellia carterii, Zingiber officinale, and Achillea millefolium on severity of symptoms, anxiety, and depression in irritable bowel syndrome patients

Kazemian, Afarin, Toghiani, Ali, Shafiei, Katayoun, Afshar, Hamid, Rafiei, Rahmatollah, Memari, Mahnaz, Adibi, Peyman·2017·Journal of Research in Medical Sciences
DOI 10.4103/jrms.jrms_905_16
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Abstract

Background: Irritable bowel syndrome (IBS) is the most prevalent functional gastrointestinal disorders (FGIDs) that affects in different aspects of life and patients experienced depression and anxiety more than others. There are several herbal medicines with positive effects in these patients. The aim of this study is to evaluate the effects of mixture of Boswellia carterii , Zingiber officinale , and Achillea Millefolium on severity of symptoms, anxiety, and depression in IBS patients. Materials and Methods: This clinical trial study was done in sixty IBS patients (with mild-to-moderate symptoms) divided into two case and control groups. Patients were assessed at the beginning, 1 month, and 3 months after by IBS-severity scoring system (IBS-SSS) and Hospital Anxiety and Depression Scale. IBS-SSS is used for quality of life evaluation too. Results: Sixty IBS patients (with mild to moderate symptoms) with a mean age of 38.75 ± 11.74 participated that 55.4% of cases and 72.8% of controls were men. The most prevalent type of IBS was the mixed type of IBS. The mean score of abdominal pain severity and frequency, bloating score, and depression and anxiety score were decreased in patients administered herbal medication, but changes in these variables in controls were not statistically significant. The changes in quality of life score between cases and controls were significant in men ( P = 0.01) although it was not significant in women. Conclusion: A mixture of B. Carterii , Z. officinale , and A. millefolium is effective in eliminating IBS symptoms and its related depression and anxiety and using herbal medicine in IBS treatment is suggested.

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Research works printed but not linked: 47

  1. Sood, 2016, Diagnosis: Rome IV criteria for FGIDs-An improvement or more of the same?, Nat Rev Gastroenterol Hepatol, 13, 501, 10.1038/nrgastro.2016.110 · DOI
  2. Adibi, 2012, Irritable bowel syndrome symptoms during pregnancy trimesters, J Res Med Sci, 17, S171
  3. Adibi, 2012, Upper functional gastrointestinal disorders in young adults, Med Arh, 66, 89, 10.5455/medarh.2012.66.89-91 · DOI
  4. Adibi, 2011, Change in functional bowel symptoms after prostatectomy: A case-control study, J Res Med Sci, 16, 130
  5. Khedmat, 2013, Aloe vera in treatment of refractory irritable bowel syndrome: Trial on Iranian patients, Journal of Research in Medical Sciences, 18, 732
  6. Moussaieff, 2012, Incensole acetate reduces depressive-like behavior and modulates hippocampal BDNF and CRF expression of submissive animals, J Psychopharmacol, 26, 1584, 10.1177/0269881112458729 · DOI
  7. Yassin, 2013, Effect of Boswellia serrata on Alzheimer's disease induced in rats, J Arab Soc Med Res, 8, 1, 10.4103/1687-4293.132766 · DOI
  8. Ammon, 2006, Boswellic acids in chronic inflammatory diseases, Planta Med, 72, 1100, 10.1055/s-2006-947227 · DOI · Paper page
  9. Nasri, 2013, Preventive and curative effects of ginger extract against histopathologic changes of gentamicin-induced tubular toxicity in rats, Int J Prev Med, 4, 316
  10. Farzin, 2013, Antidepressant effect of methanolic ginger extract in diabetic mice using forcedswim test, Journal of Mazandaran University of Medical Sciences, 23, 208
  11. Sanmukhani, 2014, Efficacy and safety of curcumin in major depressive disorder: A randomized controlled trial, Phytother Res, 28, 579, 10.1002/ptr.5025 · DOI
  12. Saeidnia, 2009, Cytotoxic flavonoid from Achillea talagonica bioss, J Med Plants, 1, 52
  13. Baretta, 2012, Anxiolytic-like effects of acute and chronic treatment with Achillea millefolium L. Extract, J Ethnopharmacol, 140, 46, 10.1016/j.jep.2011.11.047 · DOI
  14. Sarris, 2013, Plant-based medicines for anxiety disorders, part 2: A review of clinical studies with supporting preclinical evidence, CNS Drugs, 27, 301, 10.1007/s40263-013-0059-9 · DOI
  15. Ko, 2011, Effect of herbal extract granules combined with probiotic mixture on irritable bowel syndrome with diarrhea: Study protocol for a randomized controlled trial, Trials, 12, 219, 10.1186/1745-6215-12-219 · DOI
  16. Yang, 2012, Anti-inflammatory activities of a Chinese herbal formula IBS-20 in vitro and in vivo, Evid Based Complement Alternat Med, 2012, 491496, 10.1155/2012/491496 · DOI
  17. Li, 2013, Syndrome differentiation in chinese herbal medicine for irritable bowel syndrome: A literature review of randomized trials, Evid Based Complement Alternat Med, 2013, 232147
  18. Rahimi, 2012, Herbal medicines for the management of irritable bowel syndrome: A comprehensive review, World J Gastroenterol, 18, 589, 10.3748/wjg.v18.i7.589 · DOI
  19. Montazeri, 2003, The hospital anxiety and depression scale (HADS): Translation and validation study of the Iranian version, Health Qual Life Outcomes, 1, 14, 10.1186/1477-7525-1-14 · DOI · Paper page
  20. Gholamrezaei, 2010, Evaluation of treatment outcome measures in irritable bowel syndrome clinical trials, Govaresh, 14, 219
  21. Schuhly, 2004, Pharmacognosy: Phytochemistry, medicinal plants, Phytomedicine, 11, 90
  22. Applequist, 2011, Yarrow (Achillea millefolium L.): A neglected Panacea? A review of ethnobotany, bioactivity, and biomedical research1, Econ Bot, 65, 209, 10.1007/s12231-011-9154-3 · DOI
  23. Dalsenter, 2004, Reproductive evaluation of aqueous crude extract of Achillea millefolium L. (Asteraceae) in Wistar rats, Reprod Toxicol, 18, 819, 10.1016/j.reprotox.2004.04.011 · DOI
  24. Cavalcanti, 2006, Safety and antiulcer efficacy studies of Achillea millefolium L. after chronic treatment in Wistar rats, J Ethnopharmacol, 107, 277, 10.1016/j.jep.2006.03.011 · DOI
  25. Liebregts, 2007, Immune activation in patients with irritable bowel syndrome, Gastroenterology, 132, 913, 10.1053/j.gastro.2007.01.046 · DOI · Paper page
  26. Maynard, 2009, Intestinal effector T cells in health and disease, Immunity, 31, 389, 10.1016/j.immuni.2009.08.012 · DOI
  27. Dinan, 2006, Hypothalamic-pituitary-gut axis dysregulation in irritable bowel syndrome: Plasma cytokines as a potential biomarker?, Gastroenterology, 130, 304, 10.1053/j.gastro.2005.11.033 · DOI · Paper page
  28. Barbara, 2007, Mast cell-dependent excitation of visceral-nociceptive sensory neurons in irritable bowel syndrome, Gastroenterology, 132, 26, 10.1053/j.gastro.2006.11.039 · DOI · Paper page
  29. Ohman, 2009, B-cell activation in patients with irritable bowel syndrome (IBS), Neurogastroenterol Motil, 21, 644, 10.1111/j.1365-2982.2009.01272.x · DOI · Paper page
  30. Gómez, 1999, Study of the topical anti-inflammatory activity of Achillea ageratum on chronic and acute inflammation models, Z Naturforsch C, 54, 937, 10.1515/znc-1999-1113 · DOI
  31. Bairagi, 2012, Anti-inflammatory evaluation of methanol extract and aqueous fraction of the bark of Bauhinia variegata (Leguminosae), Int J Res Pharm Chem, 2, 77
  32. Ardestani, 2007, Antioxidant and free radical scavenging potential of Achillea santolina extracts, Food Chem, 104, 21, 10.1016/j.foodchem.2006.10.066 · DOI
  33. Lako, 2004, Total antioxidant capacity and selected flavonols and carotenoids of some Australian and Fijian fruits and vegetables, Asia Pac J Clin Nutr, 13, S127
  34. Murcia, 2004, Antioxidant evaluation in dessert spices compared with common food additives. Influence of irradiation procedure, J Agric Food Chem, 52, 1872, 10.1021/jf0303114 · DOI
  35. Thomson, 2002, The use of ginger (Zingiber officinale Rosc.) as a potential anti-inflammatory and antithrombotic agent, Prostaglandins Leukot Essent Fatty Acids, 67, 475, 10.1054/plef.2002.0441 · DOI · Paper page
  36. Jagetia, 2003, Influence of ginger rhizome (Zingiber officinale rosc) on survival, glutathione and lipid peroxidation in mice after whole-body exposure to gamma radiation, Radiat Res, 160, 584, 10.1667/RR3057 · DOI
  37. Baliga, 2003, Evaluation of nitric oxide scavenging activity of certain spices in vitro: A preliminary study, Nahrung, 47, 261, 10.1002/food.200390061 · DOI
  38. Liu, 2003, Effect of Zingiber officinale Rosc on lipid peroxidation in hyperlipidemia rats, Wei Sheng Yan Jiu, 32, 22
  39. Su, 2012, Evaluation of the anti-inflammatory and analgesic properties of individual and combined extracts from Commiphora myrrha, and Boswellia carterii, J Ethnopharmacol, 139, 649, 10.1016/j.jep.2011.12.013 · DOI
  40. Fan, 2005, Effects of an acetone extract of Boswellia carterii Birdw. (Burseraceae) gum resin on adjuvant-induced arthritis in lewis rats, J Ethnopharmacol, 101, 104, 10.1016/j.jep.2005.03.033 · DOI
  41. Vejdani, 2006, The efficacy of an herbal medicine, Carmint, on the relief of abdominal pain and bloating in patients with irritable bowel syndrome: A pilot study, Dig Dis Sci, 51, 1501, 10.1007/s10620-006-9079-3 · DOI
  42. Keshteli, 2015, Epidemiological features of irritable bowel syndrome and its subtypes among Iranian adults, Ann Gastroenterol, 28, 253
  43. Pires, 2009, Antinociceptive peripheral effect of Achillea millefolium L. And Artemisia vulgaris L.: Both plants known popularly by brand names of analgesic drugs, Phytother Res, 23, 212, 10.1002/ptr.2589 · DOI
  44. Tekieh, 2011, Anti-hyperalgesic and anti-inflammatory effects of Achillea santolina and Stachys athorecalyx extracts on complete Freund's adjuvant – Induced short-term inflammation in male Wistar rats, Koomesh, 12, 305
  45. Reanmongkol, 2005, Antinociceptive activity of the alkaloid extract from Kopsia macrophylla leaves in mice, Songklanakarin J Sci Technol, 27, 509
  46. Narayana, 2001, Bioflavonoids classification, pharmacological, biochemical effects and therapeutic potential, Indian J Pharmacol, 33, 2
  47. Duracinsky, 2009, How can an effective drug to treat irritable bowel syndrome be successfully developed?, Gastroenterol Clin Biol, 33, S26, 10.1016/S0399-8320(09)71522-2 · DOI

Cited by

Metadata

Authors
Kazemian, A., Toghiani, A., Shafiei, K., Afshar, H., Rafiei, R., Memari, M., & Adibi, P.
Affiliations
  • Department of Psychiatry, Isfahan University of Medical Sciences, Isfahan, Iran
  • Social Security Organization, Iran
  • Department of Psychiatry, Behavioral Research Center, Najafabad, Iran
  • Psychosomatic Research Center, Najafabad, Iran
  • Islamic Azad University, Najafabad Branch, Najafabad, Iran
  • Integrative Functional Gastroenterology Research Center, Isfahan University of Medical Sciences, Isfahan, Iran
Venue
Journal of Research in Medical Sciences
Publisher
Ovid Technologies (Wolters Kluwer Health)
Published
2017-01
Volume
22
Issue
1
ISSN
  • 1735-1995
  • 1735-7136
DOI
10.4103/jrms.jrms_905_16
Cited by
21
References
2
Language
en

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