Cited by 94Probiotics and Fermented FoodsGut microbiota and healthSteroid Chemistry and Biochemistry

Isolation of cholesterol-lowering lactic acid bacteria from human intestine for probiotic use

Open access
Lim, Hyeong Jun, Kim, So Young, Lee, Wan Kyu·2004·Journal of Veterinary Science

Abstract

Cholesterol-lowering effect of lactic acid bacteria (LAB: Streptococcus, Lactobacillus and Bifidobacterium) is well-known. Thus, we investigated LAB isolated from human intestine on the cholesterol-lowering effect in vitro. Seven Streptococcus (61.1%), 11 Lactobacillus (71.8%) and 7 Bifidobacterium (27.9%) were isolated as acid (pH 2.5 and 3.0) and bile (0.3% oxgall) tolerant strains. Streptococcus HJS-1, Lactobacillus HJL-37 and Bifidobacterium HJB-4 were finally selected as probiotic strains to use through the bile salt hydrolase (BSH) activity assay by using MRS media added taurodeoxycholic acid (TDCA) and the cholesterol-lowering test by using soluble cholesterol containing MRS broth. These studies suggested that the isolated LAB had an excellent hypocholesterolemic effect.

Integrity signals

Registry

Crossref · 10.4142/jvs.2004.5.4.391

Cites

14 of 14 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

We couldn’t retrieve this paper’s full text, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Cites

Flagged first, then by citations

Cited by

Sorted by citations

Authors
Lim, H. J., Kim, S. Y., & Lee, W. K.
Affiliations
Chungbuk National University (KR)
Venue
Journal of Veterinary Science
Publisher
XMLink
Published
2004
Volume
5
Issue
4
Pages
391
ISSN
1229-845X (ISSN-L)
OpenAlex
W2223751714
Cited by
94
References
14
Citations by year
2026: 2 · 2025: 4 · 2024: 2 · 2023: 2 · 2022: 7 · 2021: 3 · 2020: 5 · 2019: 2 · 2018: 11 · 2017: 2 · 2016: 2 · 2015: 6 · 2014: 4 · 2013: 5 · 2012: 4
FWCI
4.22
Type
journal article
Language
en
Open access
Locations
  • Journal of Veterinary Science (publishedVersion)
  • PubMed (publishedVersion)
Funders
Chungbuk National University
Topics
  • Life Sciences › Agricultural and Biological Sciences › Food Science › Probiotics and Fermented Foods
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gut microbiota and health
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Steroid Chemistry and Biochemistry
Keywords
lactic acid bacteria, cholesterol-lowering effect, hypocholesterolemic activity, probiotic strains, human gut microbiome, bile tolerance, acid resistance, Lactobacillus, Streptococcus, Bifidobacterium, taurodeoxycholic acid
MeSH terms
Amidohydrolases, Bifidobacterium, Cholesterol, Feces, Female, Humans, Intestines, Lactobacillus, Male, Streptococcus, Taurodeoxycholic Acid, Probiotics

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review