The DOI matches its Crossref record; 48 of the 48 references it cites were found in a registry or an index.
Therapeutic Potential of Boron-Containing Compounds
Abstract
Relative to carbon, hydrogen, nitrogen and oxygen, very little is currently known about boron in therapeutics. In addition, there are very few boron-containing natural products identified to date to serve as leads for medicinal chemists. Perceived risks of using boron and lack of synthetic methods to handle boron-containing compounds have caused the medicinal chemistry community to shy away from using the atom. However, physical, chemical and biological properties of boron offer medicinal chemists a rare opportunity to explore and pioneer new areas of drug discovery. Boron therapeutics are emerging that show different modes of inhibition against a variety of biological targets. With one boron-containing therapeutic agent on the market and several more in various stages of clinical trials, the occurrence of this class of compound is likely to grow over the next decade and boron could become widely accepted as a useful element in future drug discovery.
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Boron-containing inhibitors of synthetases
Baker, S. J., Tomsho, J. W., & Benkovic, S. J. (2011) · Chemical Society Reviews · doi:10.1039/c0cs00131g · Cited by 256
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Metadata
- Authors
- Baker, S. J., Ding, C. Z., Akama, T., Zhang, Y.-K., Hernandez, V., & Xia, Y.
- Venue
- Future Medicinal Chemistry
- Publisher
- Informa UK Limited
- Published
- 2009-10
- Volume
- 1
- Issue
- 7
- Pages
- 1275-1288
- ISSN
- 1756-8919 (ISSN-L)
- 1756-8927
- OpenAlex
- W2152933949
- Cited by
- 373
- References
- 48
- FWCI
- 6.11
- Type
- journal article
- Language
- en
- Open access
- closed
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