Autophagy and aging: The importance of maintaining "clean" cells

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Items 401–500 of 792

1. MicroRNA‐34a: A Key Regulator in the Hallmarks of Renal Cell Carcinoma
   Eman Ali Toraih, Afaf Taha Ibrahiem, Manal Said Fawzy, Mohammad Hosny Hussein, Saeed Awad M. Alqahtani, Aly A. M. Shaalan · 2017 · Oxidative Medicine and Cellular Longevity
2. Mangiferin enhances endochondral ossification‐based bone repair in massive bone defect by inducing autophagy through activating AMP‐activated protein kinase signaling pathway
   Yun Bai, Chuan Liu, Lei Fu, Xiaoshan Gong, Ce Dou, Zhen Cao, Hongyu Quan, Jian‐Mei Li, Fei Kang, Jingjin Dai et al. · 2018 · The FASEB Journal
3. How autophagy can restore proteostasis defects in multiple diseases?
   Vibhuti Joshi, Arun Upadhyay, Vijay Kumar Prajapati, Amit Mishra · 2020 · Medicinal Research Reviews
4. New Molecular Targets for Antidepressant Drugs
   Johannes Kornhuber, Erich Gulbins · 2021 · Pharmaceuticals
5. Autophagy in neuronal cell loss: a road to death
   Krisztina Takács‐Vellai, Andrew Bayci, Tibor Vellai · 2006 · BioEssays
6. Parallel damage in mitochondrial and lysosomal compartments promotes efficient cell death with autophagy: The case of the pentacyclic triterpenoids
   Waleska K. Martins, Erico Tosoni Costa, Mário Costa Cruz, Beatriz Simonsen Stolf, Ronei Miotto, Rodrigo M. Cordeiro, Maurı́cio S. Baptista · 2015 · Scientific Reports
7. Tert-buthylhydroquinone pre-conditioning exerts dual effects in old female rats exposed to 3-nitropropionic acid
   Alejandro Silva‐Palacios, Ana Laura Colín-González, Stefanie Paola López-Cervantes, Cecilia Zazueta, Armando Luna‐López, Abel Santamarı́a, Mina Königsberg · 2017 · Redox Biology
8. Autophagy regulates the degeneration of the auditory cortex through the AMPK-mTOR-ULK1 signaling pathway
   Jie Yuan, Xueyan Zhao, Yujuan Hu, Haiying Sun, Guoqing Gong, Xiang Huang, Xubo Chen, Mingyu Xia, Chen Sun, Qilin Huang et al. · 2018 · International Journal of Molecular Medicine
9. Autophagy in the Aging and Experimental Ocular Hypertensive Mouse Model
   April Nettesheim, Angela Dixon, Myoung Sup Shim, Aislyn Coyne, Molly M. Walsh, Paloma B. Liton · 2020 · Investigative Ophthalmology & Visual Science
10. Extracellular stimulation of VSIG4/complement receptor Ig suppresses intracellular bacterial infection by inducing autophagy
    Kwang H. Kim, Beom Kyu Choi, Young H. Kim, Chungyong Han, Ho Sik Oh, Don G. Lee, Byoung Se Kwon · 2016 · Autophagy
11. Reduced protein turnover mediates functional deficits in transgenic mice expressing the 25 kDa C-terminal fragment of TDP-43
    Caccamo, Antonella, Shaw, Darren M., Guarino, Francesca, Messina, Angela, Walker, Aaron W., Oddo, Salvatore · 2015 · Human Molecular Genetics
12. Targeting the autophagy pathway for cancer chemoprevention
    Meredith A. Steeves, Frank Charles Dorsey, John L. Cleveland · 2010 · Current Opinion in Cell Biology
13. Inhibition of autophagy alleviates the senescent state of rat mesenchymal stem cells during long-term culture
    Yong Zheng, Chengjun Hu, Ruhong Zhuo, Yueshan Lei, Nana Han, LIU HE · 2014 · Molecular Medicine Reports
14. Hypoxia Inducible Factor-1α Is a Regulator of Autophagy in Osteoarthritic Chondrocytes
    Junren Lu, Yi Peng, Jiapeng Zou, Jiayi Wang, Shunyi Lu, Tengfei Fu, Libo Jiang, Chi Zhang, Jian Zhang · 2021 · Cartilage
15. Mitochondrial Ca2+ homeostasis in lysosomal storage diseases
    Kirill I. Kiselyov, Shmuel Muallem · 2008 · Cell Calcium
16. Aging, metabolism and stem cells: Spotlight on muscle stem cells
    García-Prat, Laura, Muñoz-Cánoves, Pura · 2017 · Molecular and Cellular Endocrinology
17. Aging – What it is and how to measure it
    Maryam Keshavarz, Kan Xie, Daniele Bano, Dan Ehninger · 2023 · Mechanisms of Ageing and Development
18. Autophagy and Self-Defense
    Jesús Martı́nez-Borra, Carlos López‐Larrea · 2012 · Advances in experimental medicine and biology
19. A novel antitumour strategy using bidirectional autophagic vesicles accumulation via initiative induction and the terminal restraint of autophagic flux
    Yang Wang, Xiaowei Tai, Li Zhang, Yayuan Liu, Huile Gao, Jiantao Chen, Kairong Shi, Qianyu Zhang, Zhirong Zhang, Qin He · 2014 · Journal of Controlled Release
20. Protein recycling pathways in neurodegenerative diseases
    Faisal Fecto, Y. Taylan Esengul, Teepu Siddique · 2014 · Alzheimer s Research & Therapy
21. The role of STAT3/mTOR-regulated autophagy in angiotensin II-induced senescence of human glomerular mesangial cells
    Shuang Yang, Dan Sun, Lining Wang, Xiuying Wang, Mai Shi, Xue Jiang, Xinran Gao · 2018 · Cellular Signalling
22. Does Data-Independent Acquisition Data Contain Hidden Gems? A Case Study Related to Alzheimer’s Disease
    Evan E. Hubbard, Lilian R. Heil, Gennifer E. Merrihew, Jasmeer P. Chhatwal, Martin Rhys Farlow, Catriona McLean, Bernardino Francesco Ghetti, Kathy L. Newell, Matthew P. Frosch, Randall John Bateman et al. · 2021 · Journal of Proteome Research
23. Mitochondrial Autophagy and Lipofuscin Accumulation in Aging Odontoblasts
    Eduardo Couve, R. Osorio, Oliver Schmachtenberg · 2012 · Journal of Dental Research
24. Compromised autophagy precedes meniscus degeneration and cartilage damage in mice
    Jeanie Kwok Meckes, Beatriz Caramés, Merissa Olmer, William Bill Kiosses, Shawn Patrick Grogan, M.K. Lotz, Darryl D. DʼLima · 2017 · Osteoarthritis and Cartilage
25. Regulatory role of exercise-induced autophagy for sarcopenia
    Liang, Jiling, Zeng, Zhengzhong, Zhang, Ying, Chen, Ning · 2020 · Experimental Gerontology
26. MtDNA mutations, functional decline and turnover of mitochondria in aging
    Cheng‐Yoong Pang · 2008 · Frontiers in bioscience
27. Docosahexaenoic acid-mediated protein aggregates may reduce proteasome activity and delay myotube degradation during muscle atrophy in vitro
    Seung Kyun Shin, Ji Hyeon Kim, Jung Hoon Lee, Young Hoon Son, Min Wook Lee, Hak Joong Kim, Sue Ah Noh, Kwang Pyo Kim, In Gyu Kim, Min Jae Lee · 2017 · Experimental & Molecular Medicine
28. The Impact of Aging on Macroautophagy in the Pre-ovulatory Mouse Oocyte
    Alexandra E. Peters, Shandelle Caban, Eileen A. McLaughlin, Shaun D. Roman, Elizabeth G. Bromfield, Brett Nixon, Jessie M. Sutherland · 2021 · Frontiers in Cell and Developmental Biology
29. Impact of aging on heat shock protein expression in the substantia nigra and striatum of the female rat
    Amanda M. Gleixner, Sree H Pulugulla, Deepti B. Pant, Jessica M. Posimo, Tyler S. Crum, Rehana K. Leak · 2014 · Cell and Tissue Research
30. Attenuation of Adverse Effects of Aging on Skeletal Muscle by Regular Exercise and Nutritional Support
    Arthur S. Leon · 2015 · American Journal of Lifestyle Medicine
31. Mini-Review on Lipofuscin and Aging: Focusing on The Molecular Interface, The Biological Recycling Mechanism, Oxidative Stress, and The Gut-Brain Axis Functionality
    Ovidiu‐Dumitru Ilie, Alin Stelian Ciobica, Sorin Riga, Nitasha Dhunna, Jack McKenna, Ioannis Asterios Mavroudis, Bogdan Doroftei, Adela Magdalena Ciobanu, Dan Riga · 2020 · Medicina
32. Prenatal dexamethasone exposure caused fetal rats liver dysplasia by inhibiting autophagy-mediated cell proliferation
    Dingmei Zhang, Kexin Liu, Wen Hu, Xiaoqian Lu, Li Li, Zhang Qi, Hegui Huang, Hui Wang · 2021 · Toxicology
33. Monitoring autophagy in live cells with a fluorescent light-up probe for G-quadruplex structures.
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34. Nutrition and microRNAs: Novel Insights to Fight Sarcopenia
    Alessandra Barbiera, Laura Pelosi, Gigliola Sica, Bianca Maria Scicchitano · 2020 · Antioxidants
35. Bach2 regulates autophagy to modulate UVA-induced photoaging in skin fibroblasts
    Mei Wang, Mingxing Lei, Li Chang, Xing Yang, Yingying Guo, Charareh Pourzand, Jörg Walter Bartsch, Jingyi Chen, Jiefu Luo, Vega Widya Karisma et al. · 2021 · Free Radical Biology and Medicine
36. Chlorogenic Acid Modulates Autophagy by Inhibiting the Activity of ALKBH5 Demethylase, Thereby Ameliorating Hepatic Steatosis
    Fantong Meng, Chengchuang Song, Jia Liu, Fangfang Chen, Yuhua Zhu, Xingtang Fang, Qinghe Cao, Daifu Ma, Yanhong Wang, Chunlei Zhang · 2023 · Journal of Agricultural and Food Chemistry
37. Toxic effects of d -galactose on thymus and spleen that resemble aging
    Mohammad Nizam Uddin, Naomi Nishio, Sachiko Ito, Haruhiko Suzuki, Ken‐ichi Isobe · 2010 · Journal of Immunotoxicology
38. Cooperation between proteolytic systems in cardiomyocyte recycling
    Osamu Yamaguchi, Manabu Taneike, Kinya Otsu · 2012 · Cardiovascular Research
39. The role of Neurochemicals, Stress Hormones and Immune System in the Positive Feedback Loops between Diabetes, Obesity and Depression
    Julian Bryant Wilson, Ma’ayan Epstein, Briana Lopez, Amira K. Brown, Kabirullah Lutfy, Theodore C. Friedman · 2023 · Frontiers in Endocrinology
40. Nicotinamide Treatment Facilitates Mitochondrial Fission through Drp1 Activation Mediated by SIRT1-Induced Changes in Cellular Levels of cAMP and Ca2+
    Seon Beom Song, Jin‐Sung Park, So Young Jang, Eun Seong Hwang · 2021 · Cells
41. Potentiating bacterial cancer therapy using hydroxychloroquine liposomes
    Ying Wang, Zixuan Zhou, Wenfei Chen, Ming Qin, Zhirong Zhang, Tao Gong, Xun Sun · 2018 · Journal of Controlled Release
42. Disrupted apolipoprotein L1-miR193a axis dedifferentiates podocytes through autophagy blockade in an APOL1 risk milieu
    Kumar, Vinod, Ayasolla, Kamesh, Jha, Alok, Mishra, Abheepsa, Vashistha, Himanshu, Lan, Xiqian, Qayyum, Maleeha, Chinnapaka, Sushma, Purohit, Richa, Mikulak, Joanna et al. · 2019 · American Journal of Physiology-Cell Physiology
43. Chemical principles for the design of a novel fluorescent probe with high cancer-targeting selectivity and sensitivity
    Chi‐Chih Kang, Wei-Chun Huang, Chiung-Wen Kouh, Zi-Fu Wang, Chih‐Chien Cho, Cheng‐Chung Chang, Chiung‐Lin Wang, Ta‐Chau Chang, Joachim Seemann, Lily Jun-shen Huang · 2013 · Integrative Biology
44. Lifespan extension without fertility reduction following dietary addition of the autophagy activator Torin1 in Drosophila melanogaster
    Janet S. Mason, Tom Wileman, Tracey Chapman · 2018 · PLoS ONE
45. Increased hippocampal accumulation of autophagosomes predicts short-term recognition memory impairment in aged mice
    V. Soontornniyomkij, V. Risbrough, J. Young, B. Soontornniyomkij, D. Jeste, C. Achim · 2011 · AGE
46. Obesity is a common soil for premature cardiac aging and heart diseases - Role of autophagy
    Mingming Sun, Ying Tan, Maimaiti Rexiati, Maolong Dong, Wei Guo · 2018 · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
47. Aging Biology in the Kidney
    Markus Bitzer, Jocelyn E. Wiggins · 2015 · Advances in Chronic Kidney Disease
48. Major trauma and acceleration of the ageing process
    Jack Sullivan, Leda Mirbahai, Janet M. Lord · 2018 · Ageing Research Reviews
49. Lifelong Football Training: Effects on Autophagy and Healthy Longevity Promotion
    Annamaria Mancini, Daniela Vitucci, Morten Bredsgaard Randers, Jakob Friis Schmidt, Marie Hagman, Thomas Rostgaard Andersen, Esther Imperlini, Annalisa Mandola, Stefania Orrù, Peter Krustrup et al. · 2019 · Frontiers in Physiology
50. Crosstalk between exosomes signaling pathway and autophagy flux in senescent human endothelial cells
    Shadi Mahbubfam, Jafar Rezaie, Vahid Nejati · 2022 · Tissue and Cell
51. Hypoxia-Reoxygenation Impairs Autophagy-Lysosomal Machinery in Primary Human Trophoblasts Mimicking Placental Pathology of Early-Onset Preeclampsia
    Shi‐Bin Cheng, Zheping Huang, Sukanta Jash, Kathleen Wu, Shigeru Saito, Akitoshi Nakashima, Surendra Sharma · 2022 · International Journal of Molecular Sciences
52. Trends and recent progresses of selenium nanoparticles as novel autophagy regulators for therapeutic development
    Dongsheng Chen, Hongmei Lu, Yuhe Ma, Yuhe Huang, Tangxin Zhang, Shuhao Fan, Wensen Lin, Yifan Huang, Hua Jin, Yongdui Ruan et al. · 2023 · Frontiers in Nutrition
53. Autophagy and Longevity: Lessons from C. elegans
    Kailiang Jia, Beth Levine · 2010 · Advances in experimental medicine and biology
54. A Genome Scale Screen for Mutants with Delayed Exit from Mitosis: Ire1-Independent Induction of Autophagy Integrates ER Homeostasis into Mitotic Lifespan
    Ata Ghavidel, Kunal Baxi, Vladimir Ignatchenko, Martin A. Prusinkiewicz, Terra Arnason, Thomas Kislinger, Carlos Egydio de Carvalho, Troy A. A. Harkness · 2015 · PLoS Genetics
55. Autophagy: Can it become a potential therapeutic target? (Review)
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56. Towards an Understanding of the Anti-Aging Mechanism of Caloric Restriction
    Gabriella Cavallini, Alessio Donati, Z. Gori, Ettore Bergamini · 2008 · Current Aging Science
57. Role of the Ubiquitin–Proteasome in Protein Quality Control and Signaling
    Fu Shang, Allen Taylor · 2012 · Progress in molecular biology and translational science
58. Lazarillo-related Lipocalins confer long-term protection against type I Spinocerebellar Ataxia degeneration contributing to optimize selective autophagy
    Manuela del Caño-Espinel, Judith R Acebes, Diego Sánchez, María Dolores Ganfornina · 2015 · Molecular Neurodegeneration
59. Tor1 regulates protein solubility in Saccharomyces cerevisiae
    Theodore W. Peters, Matthew J. Rardin, Gregg A. Czerwieniec, Uday S. Evani, Pedro Reis Rodrigues, Gordon J. Lithgow, Sean David Mooney, Bradford W. Gibson, Robert E. Hughes · 2012 · Molecular Biology of the Cell
60. Brain metabolism as a modulator of autophagy in neurodegeneration.
    Yun Lim, Hanchae Cho, Eun-Kyoung Kim · 2016 · Brain Research
61. Autophagy Suppression by Appendicitis and Appendectomy Protects Against Colitis
    Rajkumar Cheluvappa, Annie S. Luo, Michael Grimm · 2014 · Inflammatory Bowel Diseases
62. Young plasma attenuates age‐dependent liver ischemia reperfusion injury
    Anding Liu, Jiankun Yang, Qi Zhou Hu, Olaf Dirsch, Uta Dahmen, Cuntai Zhang, David A. Gewirtz, Haoshu Fang, Jian Sun · 2018 · The FASEB Journal
63. Saponins of Panax japonicus Confer Neuroprotection against Brain Aging through Mitochondrial Related Oxidative Stress and Autophagy in Rats
    Jingzhi Wan, Rui Wang, Zhi-yong Zhou, Lili Deng, Changcheng Zhang, Chaoqi Liu, Haixia Zhao, Chengfu Yuan, Yumin He, Yaoyan Dun et al. · 2019 · Current Pharmaceutical Biotechnology
64. PARP1 Impedes SIRT1-Mediated Autophagy during Degeneration of the Retinal Pigment Epithelium under Oxidative Stress.
    Ki-Hong Jang, Yeseong Hwang, Eunhee Kim · 2020 · PubMed Central
65. Autophagy Signaling by Neural-Induced Human Adipose Tissue-Derived Stem Cell-Conditioned Medium during Rotenone-Induced Toxicity in SH-SY5Y Cells
    Mahesh Ramalingam, Han‐Seong Jeong, Jinsu Hwang, Hyong‐Ho Cho, Byeong Chae Kim, Eungpil Kim, Sujeong Jang · 2022 · International Journal of Molecular Sciences
66. Transcription factors and cognate signalling cascades in the regulation of autophagy
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67. A quick signal of starvation induced autophagy: Transcription versus post-translational modification of LC3
    Md. Razaul Karim, Hisayo Kawanago, Motoni Kadowaki · 2014 · Analytical Biochemistry
68. Calorie restriction increases telomerase activity, enhances autophagy, and improves diastolic dysfunction in diabetic rat hearts
    Naoki Makino, Jun‐ichi Oyama, Toyoki Maeda, Masamichi Koyanagi, Yoshihiro Higuchi, Keiko Tsuchida · 2015 · Molecular and Cellular Biochemistry
69. Study of respiratory chain dysfunction in heart disease
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70. Baicalin alleviates 6-hydroxydopamine-induced neurotoxicity in PC12 cells by down-regulation of microRNA-192-5p
    Chunyang Kang, Libo Wang, Mingyang Kang, Xiaoyang Liu, Yao Fu, Jian Gao · 2018 · Brain Research
71. Recent Advances on Antitumor Agents-loaded Polymeric and Lipid-based Nanocarriers for the Treatment of Brain Cancer
    Amanda C. Cano, Marta Espina, Maria L. García · 2020 · Current Pharmaceutical Design
72. Degradation of Misfolded Proteins by Autophagy: Is it a Strategy for Huntington's Disease Treatment?
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73. Impact of coffee intake on human aging: Epidemiology and cellular mechanisms
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74. The Role of Sirtuin-1 (SIRT1) in the Physiology and Pathophysiology of the Human Placenta
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75. Death-associated protein kinase (DAPK) and signal transduction: fine-tuning of autophagy in Caenorhabditis elegans homeostasis
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76. αvβ5 Integrin/FAK/PGC-1α Pathway Confers Protective Effects on Retinal Pigment Epithelium
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77. A neuronal aging pattern unique to humans and common chimpanzees
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78. Changes in mitochondrial energy utilization in young and old worker honeybees (Apis mellifera)
    Yu-Lung Chuang, Chin‐Yuan Hsu · 2012 · AGE
79. Masseter Muscle Myofibrillar Protein Synthesis and Degradation in an Experimental Critical Illness Myopathy Model
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80. Niemann-Pick Type C2 Protein Regulates Free Cholesterol Accumulation and Influences Hepatic Stellate Cell Proliferation and Mitochondrial Respiration Function
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81. Mechanisms of Age-Dependent Loss of Dietary Restriction Protective Effects in Acute Kidney Injury
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82. Autophagy-associated signal pathways of functional foods for chronic diseases
    Jinfeng Xie, Jiling Liang, Ning Chen · 2019 · Food Science and Human Wellness
83. RETRACTED: Downregulation of miRNA‐30a enhanced autophagy in osthole‐alleviated myocardium ischemia/reperfusion injury
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84. Relation Between Genetic Factors and Frailty in Older Adults
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85. Autophagy in Caenorhabditis elegans
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86. Tropomyosin Dephosphorylation Results in Compensated Cardiac Hypertrophy
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87. Autophagy in arsenic carcinogenesis
    Yuanlin Qi, Hui Li, Mingfang Zhang, Tao Zhang, Jacqueline A. Frank, Gang Chen · 2014 · Experimental and Toxicologic Pathology
88. Parkinson’s disease; the hibernating spore hypothesis
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89. Cost-effectiveness of immunization in The Gambia.
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90. Podocyte autophagy is associated with foot process effacement and proteinuria in patients with minimal change nephrotic syndrome
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91. A pilot study examining the impact of exercise training on skeletal muscle genes related to the TLR signaling pathway in older adults following hip fracture recovery
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92. Nutrient sensing: TOR's Ragtime
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93. The Role of Cellular Metabolism in Maintaining the Function of the Dentine-Pulp Complex: A Narrative Review
    Kacper Nijakowski, Martyna Ortarzewska, Jakub Jankowski, Anna Paulina Lehmann, Anna Surdacka · 2023 · Metabolites
94. CDK4/6 Inhibition on Glucose and Pancreatic Beta Cell Homeostasis in Young and Aged Rats
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95. Non-coding RNAs as regulators of autophagy in chondrocytes: Mechanisms and implications for osteoarthritis
    Chenyu Zhu, Lingli Zhang, Xiaoqing Ding, Wei Wu, Jun Zou · 2024 · Ageing Research Reviews
96. Skeletal muscle bioenergetics in aging and heart failure
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97. Autophagy Plays a Role in the Prolongation of the Life Span of Caenorhabditis elegans by Astaxanthin
    Min Fu, Xumei Zhang, Xuguang Zhang, Liu Yang, Suhui Luo, Huan Liu · 2020 · Rejuvenation Research
98. Autophagy is a key feature in the pathogenesis of systemic sclerosis
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99. In Situ Autophagy Disruption Generator for Cancer Theranostics
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100. Involvement of phosphatase and tensin homolog-induced putative kinase 1–Parkin-mediated mitophagy in septic acute kidney injury
     Xingui Dai, Wei Xu, Tao Li, Jiaying Lu, Yang Yang, Qiong Li, Zhenhua Zeng, Yuhang Ai · 2019 · Chinese Medical Journal