Autophagy in microglia degrades extracellular β-amyloid fibrils and regulates the NLRP3 inflammasome

Cho, Mi-Hyang, Cho, Kwangmin, Kang, Hoe-Jin, Jeon, Eun-Young, Kim, Hun-Sik, Kwon, Hyung-Joon, Kim, Hong-Mi, Kim, Dong-Hou +1 more·2014·Autophagy

Cited by (396)

Items 101–200 of 396

  1. The Role of the Effects of Autophagy on NLRP3 Inflammasome in Inflammatory Nervous System Diseases
    Shizhen Zhao, Xiaotian Li, jie Wang, Honggang Wang · 2021 · Frontiers in Cell and Developmental Biology
  2. Resveratrol Enhances Autophagic Flux and Promotes Ox-LDL Degradation in HUVECs via Upregulation of SIRT1
    Yan-Lin Zhang, Xueqin Cao, Wawa Zhu, Zhi-Hua Liu, Hui-Hui Liu, Yan-De Zhou, Yong-Jun Cao, Chun-Feng Liu, Ying Xie · 2016 · Oxidative Medicine and Cellular Longevity
  3. Targeting NLRP3-Mediated Neuroinflammation in Alzheimer’s Disease Treatment
    Julia Barczuk, Natalia Siwecka, Weronika Lusa, Wioletta Rozpędek‐Kamińska, Ewa Kucharska, Ireneusz Majsterek · 2022 · International Journal of Molecular Sciences
  4. NLRP3 Inflammasomes in Parkinson’s disease and their Regulation by Parkin
    Yiqun Yan, Yi Fang, Ran Zheng, Jiali Pu, Baorong Zhang · 2020 · Neuroscience
  5. Regulation of amyloid precursor protein processing by its KFERQ motif
    Ji‐Seon Park, Dong‐Hou Kim, Seung‐Yong Yoon · 2016 · BMB Reports
  6. Metabolic Regulation of Glia and Their Neuroinflammatory Role in Alzheimer's Disease
    Preeti Kumari, Anika Sood, Valencia Fernandes · 2021 · Cellular and Molecular Neurobiology
  7. Autophagy in Alzheimer's disease and promising modulatory effects of herbal medicine
    Qiang Zeng, Wing Sum Siu, Limin Li, Jin Yu, Shaoyu Liang, Meiqun Cao, Min Ma, Zhengzhi Wu · 2019 · Experimental Gerontology
  8. NLRP3-dependent microglial training impaired the clearance of amyloid-beta and aggravated the cognitive decline in Alzheimer’s disease
    Xiaofei He, Jinghui Xu, Ge Li, Mingyue Li, Lili Li, Zhong Pei, Liying Zhang, Xiquan Hu · 2020 · Cell Death and Disease
  9. Cannabidiol (CBD) enhanced the hippocampal immune response and autophagy of APP/PS1 Alzheimer's mice uncovered by RNA-seq
    Fengjin Hao, Yueqin Feng · 2020 · Life Sciences
  10. LC3-associated endocytosis and the functions of Rubicon and ATG16L1
    Joëlle Magné, Douglas R. Green · 2022 · Science Advances
  11. Cocaine Mediated Neuroinflammation: Role of Dysregulated Autophagy in Pericytes
    Susmita Sil, Fang Niu, Eric C. Tom, Ke Liao, Palsamy Periyasamy, Shilpa J. Buch · 2018 · Molecular Neurobiology
  12. Micro RNA ‐214‐3p: A link between autophagy and endothelial cell dysfunction in atherosclerosis
    J. Wang, W.‐N. Wang, Shufeng Xu, H. Wu, Bing Dai, Dan Jian, Mei Yang, Y.‐T. Wu, Q. Feng, Jianhua Zhu et al. · 2017 · Acta Physiologica
  13. Alzheimer’s disease and the autophagic-lysosomal system
    Chung, Kyung Min, Hernández, Nancy, Sproul, Andrew A., Yu, Wai Haung · 2019 · Neuroscience Letters
  14. Atorvastatin ameliorates LPS‐induced inflammatory response by autophagy via AKT/mTOR signaling pathway
    Fei Han, Qingqing Xiao, Shi Peng, Xinyu Che, Li‐Sheng Jiang, Qin Shao, Ben He · 2017 · Journal of Cellular Biochemistry
  15. Elevated Expression of MiR-17 in Microglia of Alzheimer’s Disease Patients Abrogates Autophagy-Mediated Amyloid-β Degradation
    Shady Z. K. Estfanous, Kylene P. Daily, Mostafa M. Eltobgy, Nicholas P. Deems, Midhun N. K. Anne, Kathrin Krause, Asmaa Badr, Kaitlin Hamilton, Cierra Carafice, Ahmad Hegazi et al. · 2021 · Frontiers in Immunology
  16. The protective effect of thymoquinone or/and thymol against monosodium glutamate-induced attention-deficit/hyperactivity disorder (ADHD)-like behavior in rats: Modulation of Nrf2/HO-1, TLR4/NF-κB/NLRP3/caspase-1 and Wnt/β-Catenin signaling pathways in rat model
    Karema Abu‐Elfotuh, Somaia A Abdel-Sattar, Ashwaq Najemaldeen Abbas, Yasmen F. Mahran, Aliah R. Alshanwani, Ahmed M. Hamdan, Ahmed M. Atwa, Enji Reda, Yasmin Moustafa Ahmed, Sameh S. Zaghlool et al. · 2022 · Biomedicine & Pharmacotherapy
  17. The Molecular Mechanisms of Neuroinflammation in Alzheimer’s Disease, the Consequence of Neural Cell Death
    Su-Bin Choi, Sehee Kwon, Ji-Hye Kim, Na-Hyun Ahn, Joo-Hee Lee, Seung‐Hoon Yang · 2023 · International Journal of Molecular Sciences
  18. Inhibition of mitochondrial fission and NOX2 expression prevent nlrp3 inflammasome activation in the endothelium: The role of corosolic acid action in the amelioration of endothelial dysfunction
    Li, Yi, Zhou, Zhi-Hui, Chen, Mei-Hong, Yang, Jie, Leng, Jing, Cao, Guo-Sheng, Xin, Gui-Zhong, Liu, Li-Fang, Kou, Jun-Ping, Liu, Bao-Lin et al. · 2016 · Antioxidants & Redox Signaling
  19. The effects of caloric restriction and its mimetics in Alzheimer's disease through autophagy pathways
    Yang, Yi, Zhang, Lihui · 2020 · Food & Function
  20. Exosomes, autophagy and ER stress pathways in human diseases: Cross-regulation and therapeutic approaches
    Babak Jahangiri, Ali Kian Saei, Patience O. Obi, Narjes Asghari, Shahrokh Lorzadeh, Shirin Hekmatirad, Marveh Rahmati, Fatemeh Velayatipour, Mohammad Hosseni Asghari, Ayesha Saleem et al. · 2022 · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
  21. Brain ageing and neurodegenerative disease: The role of cellular waste management
    Simona Daniele, Chiara Giacomelli, Claudia Martini · 2018 · Biochemical Pharmacology
  22. Interaction between autophagy and the NLRP3 inflammasome in Alzheimer’s and Parkinson’s disease
    Ranran Lu, Lijie Zhang, Xinling Yang · 2022 · Frontiers in Aging Neuroscience
  23. Pharmacological modulation of autophagy for Alzheimer's disease therapy: Opportunities and obstacles
    Deng, Zhiqiang, Dong, Yu, Zhou, Xiaoting, Lu, Jia-Hong, Yue, Zhenyu · 2022 · Acta Pharmaceutica Sinica B
  24. Interleukin-4 affects microglial autophagic flux
    Run-Hong Tang, Rui-Qun Qi, Hua-Yan Liu · 2019 · Neural Regeneration Research
  25. Autophagy and Inflammasome Interplay
    João Demétrio Martins, Joana Manuela Torres Liberal, Ana Beatriz Gonçalves da Silva, Isabel Ferreira, Bruno Miguel Neves, Maria Teresa Cruz · 2015 · DNA and Cell Biology
  26. Aβ promotes CD38 expression in senescent microglia in Alzheimer’s disease
    Yiran Hu, Yan Huang, Sanli Xing, Chuan Chen, Dingzhu Shen, Jiulin Chen · 2022 · Biological Research
  27. Functional analyses of major cancer-related signaling pathways in Alzheimer's disease etiology
    Jianping Guo, Ji Cheng, Brian J. North, Wenyi Wei · 2017 · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer
  28. Activating α7 nicotinic acetylcholine receptor inhibits NLRP 3 inflammasome through regulation of β‐arrestin‐1
    Ping Ke, Bo‐Zong Shao, Zhe‐Qi Xu, Xiongwen Chen, Wei Wei, Chong Liu · 2017 · CNS Neuroscience & Therapeutics
  29. Autophagy in Multiple Sclerosis: Two Sides of the Same Coin
    Chairi Misrielal, Mario Mauthe, Fulvio Reggiori, Bart J. L. Eggen · 2020 · Frontiers in Cellular Neuroscience
  30. A literature overview on epilepsy and inflammasome activation
    Parvaneh Mohseni Moghaddam, Mehrdad Roghani, Hossein Khaleghzadeh‐Ahangar, Seyed Shahabeddin Sadr, Carlo Sala · 2021 · Brain Research Bulletin
  31. Cell-autonomous immune dysfunction driven by disrupted autophagy in C9orf72 -ALS iPSC-derived microglia contributes to neurodegeneration
    Poulomi Banerjee, Arpan R. Mehta, Raja Sekhar Nirujogi, James D. Cooper, Owen G. James, Jyoti Nanda, James Longden, Karen Burr, Karina McDade, Andrea Salzinger et al. · 2023 · Science Advances
  32. AIM 2 inflammasomes regulate neuronal morphology and influence anxiety and memory in mice
    Pei-Jung Wu, Hsin-Yu Liu, Tzyy‐Nan Huang, Yi-Ping Hsueh · 2016 · Scientific Reports
  33. Cross-talk between redox signalling and protein aggregation
    Loes van Dam, Tobias B. Dansen · 2020 · Biochemical Society Transactions
  34. Targeting microglial autophagic degradation of the NLRP3 inflammasome for identification of thonningianin A in Alzheimer’s disease
    Xiao-Gang Zhou, Wenqiao Qiu, Lu Yu, Rong Pan, Jin-Feng Teng, Zhi-Pei Sang, B. Law, Ya Zhao, Li Zhang, Lu Yan et al. · 2022 · Inflammation and Regeneration
  35. Graphene oxide enhances β-amyloid clearance by inducing autophagy of microglia and neurons
    Xiaolin Li, Kai Li, Fangxuan Chu, Jie Huang, Zhuo Ru Yang · 2020 · Chemico-Biological Interactions
  36. Regulation of α-synuclein homeostasis and inflammasome activation by microglial autophagy
    Insup Choi, George R. Heaton, You-Kyung Lee, Zhenyu Yue · 2022 · Science Advances
  37. Orexin Impairs the Phagocytosis and Degradation of Amyloid-β Fibrils by Microglial Cells
    Hoyoung An, Mi-Hyang Cho, Dong‐Hou Kim, Seockhoon Chung, Seung‐Yong Yoon · 2017 · Journal of Alzheimer s Disease
  38. Therapeutic Role of Inflammasome Inhibitors in Neurodegenerative Disorders
    Lahooti, Behnaz, Chhibber, Tanya, Bagchi, Sounak, Varahachalam, Sree Pooja, Jayant, Rahul D. · 2021 · Brain, Behavior, and Immunity
  39. Spotlight on NLRP3 Inflammasome: Role in Pathogenesis and Therapies of Atherosclerosis
    Chunteng Jiang, Santuan Xie, Guang Yang, Ningning Wang · 2021 · Journal of Inflammation Research
  40. Brain–immune interaction mechanisms: Implications for cognitive dysfunction in psychiatric disorders
    Fangyi Zhao, Bingjin Li, Wei Yang, Tongtong Ge, Ranji Cui · 2022 · Cell Proliferation
  41. Advances in Amyloid-β Clearance in the Brain and Periphery: Implications for Neurodegenerative Diseases
    Rahat Ullah, Eun Jeong Lee · 2023 · Experimental Neurobiology
  42. Alzheimer's disease genes and autophagy
    Seung‐Yong Yoon, Dong‐Hou Kim · 2016 · Brain Research
  43. Autophagy Modulators and Neuroinflammation
    Kyoung Sang Cho, Jang Ho Lee, Jeiwon Cho, Guang‐Ho Cha, Gyun Jee Song · 2018 · Current Medicinal Chemistry
  44. β-amyloid: The known unknowns
    Ayton, Scott, Bush, Ashley I. · 2021 · Ageing Research Reviews
  45. ATG5 (autophagy related 5) in microglia controls hippocampal neurogenesis in Alzheimer disease
    Xin Tang, Ellen M. Walter, Eric S. Wohleb, Yanbo Fan, Chenran Wang · 2023 · Autophagy
  46. The Alzheimer's Disease-Associated R47H Variant of TREM2 Has an Altered Glycosylation Pattern and Protein Stability
    Ji‐Seon Park, In Jung Ji, Dong‐Hou Kim, Hyun Joo An, Seung‐Yong Yoon · 2017 · Frontiers in Neuroscience
  47. Roflupram, a Phosphodiesterase 4 Inhibitior, Suppresses Inflammasome Activation through Autophagy in Microglial Cells
    Tingting You, Yufang Cheng, Jiahong Zhong, Bingtian Bi, Bingqing Zeng, Wenhua Zheng, Haitao Wang, Jiangping Xu · 2017 · ACS Chemical Neuroscience
  48. Autophagy deficiency in myeloid cells exacerbates eosinophilic inflammation in chronic rhinosinusitis
    Go Eun Choi, Seung‐Yong Yoon, Jiyun Kim, Do‐Young Kang, Yong Ju Jang, Hun Sik Kim · 2017 · Journal of Allergy and Clinical Immunology
  49. α-Synuclein Accumulation in SH-SY5Y Cell Impairs Autophagy in Microglia by Exosomes Overloading MiR-19a-3p
    Tianen Zhou, Danyu Lin, Ying Chen, Sudan Peng, Xiuna Jing, Ming Lei, Enxiang Tao, Yanran Liang · 2019 · Epigenomics
  50. Neuroprotective effects of p62(SQSTM1)-engineered lactic acid bacteria in Alzheimer’s disease: a pre-clinical study
    Valentina Cecarini, Laura Bonfili, Olee Gogoi, Solomon Lawrence, Franco Maria Venanzi, Vasco Azevedo, Pamela Del Carmen Mancha-Agresti, Mariana Martins Drumond, Giacomo Rossi, Sara Berardi et al. · 2020 · Aging
  51. Aβ and Tau Regulate Microglia Metabolism via Exosomes in Alzheimer’s Disease
    Yuanxin Zhao, Buhan Liu, Jian Wang, Long Xu, Sihang Yu, Jiaying Fu, Xiaoyu Yan, Jing Su · 2022 · Biomedicines
  52. Mechanistic and therapeutic role of NLRP3 inflammasome in the pathogenesis of Alzheimer's disease
    Dhanshree Jha, Erik N.T.P. Bakker, Rahul Kewal Kumar · 2023 · Journal of Neurochemistry
  53. Natural Products that Target the NLRP3 Inflammasome to Treat Fibrosis
    Nan Ding, Bo Wei, Xiaohui Fu, Chuan Wang, Yimou Wu · 2020 · Frontiers in Pharmacology
  54. Microglial Turnover in Ageing-Related Neurodegeneration: Therapeutic Avenue to Intervene in Disease Progression
    Shofiul Azam, Md. Ezazul Haque, In‐Su Kim, Dong‐Kug Choi · 2021 · Cells
  55. Activation of CREB‐mediated autophagy by thioperamide ameliorates β‐amyloid pathology and cognition in Alzheimer’s disease
    Jiangong Wang, Bin Liu, Yong X. Xu, Meizi Yang, Chaoyun Wang, Mengmeng Song, Jing Liu, Wentao Wang, Jingjing You, Fengjiao Sun et al. · 2021 · Aging Cell
  56. Death-associated protein kinase 1 as a therapeutic target for Alzheimer's disease
    Tao Zhang, Byeong Mo Kim, Tae Ho Lee · 2024 · Translational Neurodegeneration
  57. Therapeutic Effect of Modulating TREM-1 via Anti-inflammation and Autophagy in Parkinson’s Disease
    Chien‐Wei Feng, Nan‐Fu Chen, Chun‐Sung Sung, Hsiao‐Mei Kuo, San‐Nan Yang, Chien‐Liang Chen, Han-Chun Hung, Bing‐Hung Chen, Zhi‐Hong Wen, Wu-Fu Chen · 2019 · Frontiers in Neuroscience
  58. Autophagy in Neuroinflammation: A Focus on Epigenetic Regulation
    Yu Chen, Junren Chen, Ziwei Xing, Cheng Yun Peng, Dan Li · 2023 · Aging and Disease
  59. Melatonin Reduces NLRP3 Inflammasome Activation by Increasing α7 nAChR-Mediated Autophagic Flux
    Víctor Farré‐Alins, Paloma Narros‐Fernández, Alejandra Palomino‐Antolín, Celine Decouty‐Pérez, Ana Belén López-Rodríguez, Esther Parada, Alicia Muñoz-Montero, Vanessa Gómez‐Rangel, Francisco Javier Lopez-Munoz, Eva Ramos et al. · 2020 · Antioxidants
  60. Natural Compounds for SIRT1‐Mediated Oxidative Stress and Neuroinflammation in Stroke: A Potential Therapeutic Target in the Future
    Chaoyou Fang, Houshi Xu, Ling Yuan, Zhengyang Zhu, Xiaoyu Wang, Yibo Liu, Anke Zhang, Anwen Shao, Meiqing Lou · 2022 · Oxidative Medicine and Cellular Longevity
  61. Metformin in Alzheimer’s disease: An overview of potential mechanisms, preclinical and clinical findings
    Mohammad Rafi Khezri, Keyvan Yousefi, Negin Mahboubi, Darya Hodaei, Morteza Ghasemnejad‐Berenji · 2022 · Biochemical Pharmacology
  62. Basal ryanodine receptor activity suppresses autophagic flux
    Tim Vervliet, Isabel Pintelon, Kirsten Welkenhuyzen, Martin D. Bootman, Hiroko Bannai, Katsuhiko Mikoshiba, Wim Martinet, Nael Nadif Kasri, Jan B. Parys, Geert Bultynck · 2017 · Biochemical Pharmacology
  63. Variations in the FRA10AC1 Fragile Site and 15q21 Are Associated with Cerebrospinal Fluid Aβ1-42 Level
    Qingqin S. Li, Antonio Parrado, Mahesh N. Samtani, Vaibhav A. Narayan, Alzheimer’s Disease Neuroimaging Initiative · 2015 · PLoS ONE
  64. Electroacupuncture Could Influence the Expression of IL‐1β and NLRP3 Inflammasome in Hippocampus of Alzheimer’s Disease Animal Model
    Jing Hua Jiang, Ning Ding, Kang Wang, Zhigang Li · 2018 · Evidence-based Complementary and Alternative Medicine
  65. Amyloid β oligomers inhibit growth of human cancer cells
    Božena Pavliukevičienė, Aistė Zentelytė, Marija Jankunec, Giedrė Valiulienė, Martynas Talaikis, Rūta Navakauskienė, Gediminas Niaura, Gintaras Valinčius · 2019 · PLoS ONE
  66. Autophagy impairment by caspase‐1‐dependent inflammation mediates memory loss in response to β‐Amyloid peptide accumulation
    Lourdes Álvarez‐Arellano, Martha Pedraza‐Escalona, Tonali Blanco Ayala, Nohemí Camacho‐Concha, Javier Cortés‐Mendoza, Leonor Pérez‐Martínez, Gustavo Pedraza‐Alva · 2017 · Journal of Neuroscience Research
  67. Molecular Mechanism of Autophagy: Its Role in the Therapy of Alzheimer’s Disease
    Yuan Zhao, Yidan Zhang, Jian Zhang, Xiangjian Zhang, Guofeng Yang · 2020 · Current Neuropharmacology
  68. The Potential Role of Herpes Simplex Virus Type 1 and Neuroinflammation in the Pathogenesis of Alzheimer's Disease
    Kathlyn Laval, Lynn W. Enquist · 2021 · Frontiers in Neurology
  69. Autophagy regulates cellular senescence by mediating the degradation of CDKN1A/p21 and CDKN2A/p16 through SQSTM1/p62-mediated selective autophagy in myxomatous mitral valve degeneration
    Qiyu Tang, Keyi Tang, Greg Robert Markby, Maciej Parys, Kanchan Phadwal, Vicky Elizabeth MacRae, BRENDAN M. CORCORAN · 2025 · Autophagy
  70. Lysosomal Functions in Glia Associated with Neurodegeneration
    Kreher, Conlan, Favret, Jacob, Maulik, Malabika, Shin, Daesung · 2021 · Biomolecules
  71. New Insights Into Autophagy Dysfunction Related to Amyloid Beta Toxicity and Neuropathology in Alzheimer's Disease
    Claudia Ntsapi, Dumisile Lumkwana, Chrisna Swart, André du Toit, Ben Loos · 2017 · International review of cytology
  72. Exposure to 835 MHz RF-EMF decreases the expression of calcium channels, inhibits apoptosis, but induces autophagy in the mouse hippocampus
    Ju Hwan Kim, Uy Dong Sohn, Hyunggun Kim, Hak Rim Kim · 2018 · Korean Journal of Physiology and Pharmacology
  73. Hematopoietic Cell Kinase (HCK) Is Essential for NLRP3 Inflammasome Activation and Lipopolysaccharide-Induced Inflammatory Response In Vivo
    Xiangxi Kong, Ya-Jin Liao, Lujun Zhou, Ying Zhang, Jin-Bo Cheng, Zeng-Qiang Yuan, Shukun Wang · 2020 · Frontiers in Pharmacology
  74. Neuroimmune crosstalk and evolving pharmacotherapies in neurodegenerative diseases
    Falguni Baidya, Mariya Bohra, Aishika Datta, Deepaneeta Sarmah, Birva Shah, Priya Jagtap, Swapnil Raut, Ankan Sarkar, Upasna Singh, Kiran Kalia et al. · 2020 · Immunology
  75. Secondary White Matter Injury Mediated by Neuroinflammation after Intracerebral Hemorrhage and Promising Therapeutic Strategies of Targeting the NLRP3 Inflammasome
    Linglong Xiao, Mengqi Wang, Yifeng Shi, Yangyang Xu, Yuan Gao, Wei Zhang, Yang Wu, Hao Deng, Wei Pan, Wei Wang et al. · 2022 · Current Neuropharmacology
  76. The protective effect of Epimedii Folium and Curculiginis Rhizoma on Alzheimer’s disease by the inhibitions of NF-κB/MAPK pathway and NLRP3 inflammasome
    Zhou Lan, Guangjing Xie, Wei Meng, Ping Wang, Lvyi Chen · 2017 · Oncotarget
  77. Neuronal deficiency of p38α‐MAPK ameliorates symptoms and pathology of APP or Tau‐transgenic Alzheimer’s mouse models
    Laura Schnöder, Gilles Gasparoni, Karl J. V. Nordström, Andrea Schottek, Inge Tomic, Anne Christmann, Karl Herbert Schäfer, Michael Dieter Menger, Jörn Walter, Klaus C Fassbender et al. · 2020 · The FASEB Journal
  78. Canonical and Noncanonical Autophagy Pathways in Microglia
    Julia Jülg, Laura Strohm, Christian Behrends · 2020 · Molecular and Cellular Biology
  79. Levetiracetam alleviates cognitive decline in Alzheimer’s disease animal model by ameliorating the dysfunction of the neuronal network
    Xiangyu Zheng, Yu-Dan Lv, Fengyan Jin, Haichen Zhang, Xiujuan Wu, Jie Zhu, Yang Ruan · 2022 · Frontiers in Aging Neuroscience
  80. Association between autophagy and rapid eye movement sleep loss-associated neurodegenerative and patho-physio-behavioral changes
    Amit Kumar Chauhan, Birendra Nath Mallick · 2019 · Sleep Medicine
  81. Essential Oil of Acorus tatarinowii Schott Ameliorates Aβ-Induced Toxicity in Caenorhabditis elegans through an Autophagy Pathway
    Xinyan Chen, De-Chun Liao, Menglu Sun, Xiang-huan Cui, Hongbing Wang · 2020 · Oxidative Medicine and Cellular Longevity
  82. Protective Effect of Ferulic Acid on Lipopolysaccharide-Induced BV2 Microglia Inflammation via AMPK/mTOR Signaling Pathway
    Xingru Chen, Xiaolan Zhou, Xiaoqing Cheng, Li-Ting Lin, Qi Wang, Ruoting Zhan, Qingguang Wu, Sijun Liu · 2023 · Molecules
  83. Microglia-targeted inhibition of miR-17 via mannose-coated lipid nanoparticles improves pathology and behavior in a mouse model of Alzheimer’s disease
    Asmaa Badr, Kylene P. Daily, Mostafa M. Eltobgy, Shady Z. K. Estfanous, Michelle H. Tan, Jimmy Chun‐Tien Kuo, Owen D. Whitham, Cierra Carafice, Gauruv A. Gupta, Heba M. Amer et al. · 2024 · Brain Behavior and Immunity
  84. Periodic dietary restriction ameliorates amyloid pathology and cognitive impairment in PDAPP-J20 mice: Potential implication of glial autophagy
    Amal Gregosa, Ángeles Vinuesa, María Florencia Todero, Carlos Javier Pomilio, Soledad Paola Rossi, Melisa Bentivegna, Jessica Presa, Shirley D. Wenker, Flavia Saravia, Juan Beauquis · 2019 · Neurobiology of Disease
  85. miR-Let7A Modulates Autophagy Induction in LPS-Activated Microglia
    Juhyun Song, Yumi Oh, Jong Eun Lee · 2015 · Experimental Neurobiology
  86. Trpm2 deficiency in microglia attenuates neuroinflammation during epileptogenesis by upregulating autophagy via the AMPK/mTOR pathway
    Chen Chen, Tao Zhu, Lifen Gong, Zhe Hu, Wei Hao, Jianchen Fan, Donghui Lin, Xiaojun Wang, Junyu Xu, Xinyan Dong et al. · 2023 · Neurobiology of Disease
  87. The Hallmarks of Ageing in Microglia
    Laura M. Carr, Sanam Mustafa, Lyndsey E. Collins‐Praino · 2025 · Cellular and Molecular Neurobiology
  88. Accelerated and Severe Lupus Nephritis Benefits From M1, an Active Metabolite of Ginsenoside, by Regulating NLRP3 Inflammasome and T Cell Functions in Mice
    Tsai-Jung Lin, Chung-Yao Wu, Pei‐Yi Tsai, Wan‐Han Hsu, Kuo‐Feng Hua, Ching‐Liang Chu, Yu‐Chieh Lee, Ann Chen, Sheau-Long Lee, Yijin Lin et al. · 2019 · Frontiers in Immunology
  89. Clemastine attenuates AD-like pathology in an AD model mouse via enhancing mTOR-mediated autophagy
    Zhenyu Li, Lihua Chen, Xiu‐Yun Zhao, Hong Chen, Yanyun Sun, Mei‐Hong Lu, Zhao-Tao Wang, Mei Chen, Lu Li, Wenhui Huang et al. · 2021 · Experimental Neurology
  90. Presenilin 2 N141I mutation induces hyperactive immune response through the epigenetic repression of REV-ERBα
    Hyeri Nam, Younghwan Lee, Boil Kim, Ji-Won Lee, Seohyeon Hwang, Hyun‐Kyu An, Kyung Min Chung, Young‐Jin Park, Jihyun Hong, Kyungjin Kim et al. · 2022 · Nature Communications
  91. Amyloidogenic proteins associated with neurodegenerative diseases activate the NLRP3 inflammasome
    Qian-Hang Shao, Xiaoling Zhang, Pengfei Yang, Yu‐He Yuan, Nai‐Hong Chen · 2017 · International Immunopharmacology
  92. Plasma ATG5 is increased in Alzheimer’s disease
    Sun-Jung Cho, Hyun Joung Lim, Chulman Jo, Moon Ho Park, Changsu Han, Young Ho Koh · 2019 · Scientific Reports
  93. The NLRP3 inflammasome: a therapeutic target for inflammation-associated cancers
    Mahdi Gouravani, Nastaran Khalili, Sepideh Razi, Mahsa Keshavarz‐Fathi, Neda Khalili, Nima Rezaei · 2020 · Expert Review of Clinical Immunology
  94. Pharmacological Tools to Modulate Autophagy in Neurodegenerative Diseases
    Shwetha Suresh, Anushka Chakravorty, Mridhula Giridharan, Lakshmi Garimella, Ravi R. Manjithaya · 2020 · Journal of Molecular Biology
  95. PDPK1 regulates autophagosome biogenesis by binding to PIK3C3
    Boli Hu, Yina Zhang, Tingjuan Deng, Jinyan Gu, Juan Liu, Hui Min Yang, Yuting Xu, Yan Yan, Fan Yang, Heng Zhang et al. · 2020 · Autophagy
  96. Chronic Microcystin-LR-Induced α-Synuclein Promotes Neuroinflammation Through Activation of the NLRP3 Inflammasome in Microglia
    Minghao Yan, Haibo Jin, Chun Pan, Xiaodong Han · 2022 · Molecular Neurobiology
  97. Anti-aging activity and their mechanisms of natural food-derived peptides: current advancements
    Jialong Li, Jiaojiao Wang, Ning Zhang, Ying Li, Zizhe Cai, Guanghui Li, Zhongbo Liu, Zhiping Liu, Yong Wang, Xin Shao et al. · 2023 · Food Innovation and Advances
  98. Microglial autophagy in Alzheimer’s disease and Parkinson’s disease
    Wang, Zhifu, Wang, Qi, Li, Shihua, Li, Xiao-Jiang, Yang, Weili, He, Dajian · 2023 · Frontiers in Aging Neuroscience
  99. LncRNA NEAT1 induces autophagy through epigenetic regulation of autophagy‐related gene expression in neuroglial cells
    Ziqiang Wang, Shikuan Zhang, Kun Li · 2021 · Journal of Cellular Physiology
  100. Heavy metal-induced disruption of the autophagy-lysosomal pathway: implications for aging and neurodegenerative disorders
    Shrabani Das, Lokesh Murumulla, Pritha Ghosh, Suresh Challa · 2025 · BioMetals