How to Interpret LC3 Immunoblotting

LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing.

Kabeya, Y., Mizushima, N., Ueno, T., Yamamoto, A., Kirisako, T., Noda, T., Kominami, E., Ohsumi, Y., & Yoshimori, T. (2000) · The EMBO Journal · doi:10.1093/emboj/19.21.5720 · Cited by 6,605

p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death

Bjørkøy, G., Lamark, T., Brech, A., Outzen, H., Perander, M., Øvervatn, A., Stenmark, H., & Johansen, T. (2005) · The Journal of Cell Biology · doi:10.1083/jcb.200507002 · Cited by 3,276

The role of autophagy during the early neonatal starvation period

Kuma, A., Hatano, M., Matsui, M., Yamamoto, A., Nakaya, H., Yoshimori, T., Ohsumi, Y., Tokuhisa, T., & Mizushima, N. (2004) · Nature · doi:10.1038/nature03029 · Cited by 2,865

The role of autophagy in cardiomyocytes in the basal state and in response to hemodynamic stress

Nakai, A., Yamaguchi, O., Takeda, T., Higuchi, Y., Hikoso, S., Taniike, M., Omiya, S., Mizote, I., Matsumura, Y., Asahi, M., et al. (2007) · Nature Medicine · doi:10.1038/nm1574 · Cited by 1,520

LC3, GABARAP and GATE16 localize to autophagosomal membrane depending on form-II formation

Kabeya, Y., Mizushima, N., Yamamoto, A., Oshitani-Okamoto, S., Ohsumi, Y., & Yoshimori, T. (2004) · Journal of Cell Science · doi:10.1242/jcs.01131 · Cited by 1,394

Bafilomycin A1 prevents maturation of autophagic vacuoles by inhibiting fusion between autophagosomes and lysosomes in rat hepatoma cell line, H-4-II-E cells

Yamamoto, A., Tagawa, Y., Yoshimori, T., Moriyama, Y., Masaki, R., & Tashiro, Y. (1998) · Cell Structure and Function · doi:10.1247/csf.23.33 · Cited by 1,312

Lysosomal turnover, but not a cellular level, of endogenous LC3 is a marker for autophagy

Tanida, I., Minematsu-Ikeguchi, N., Ueno, T., & Kominami, E. (2005) · Autophagy · doi:10.4161/auto.1.2.1697 · Cited by 1,108

The pre‐autophagosomal structure organized by concerted functions of APG genes is essential for autophagosome formation

Suzuki, K., Kirisako, T., Kamada, Y., Mizushima, N., Noda, T., & Ohsumi, Y. (2001) · The EMBO Journal · doi:10.1093/emboj/20.21.5971 · Cited by 1,060

Role of autophagy in temozolomide-induced cytotoxicity for malignant glioma cells

Kanzawa, T., Germano, I. M., Komata, T., Ito, H., Kondo, Y., & Kondo, S. (2004) · Cell Death and Differentiation · doi:10.1038/sj.cdd.4401359 · Cited by 995

Methods for monitoring autophagy

Mizushima, N. (2004) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/j.biocel.2004.02.005 · Cited by 899

IRE1 and CaMKKβ pathways to reveal the mechanism involved in microcystin-LR-induced autophagy in mouse ovarian cells

Ya, M., Liu, H., Du, X., Petlulu, P., Chen, X., Wang, R. Y., Zhang, S., Tian, Z., Shi, L., Guo, H., et al. (2020) · Food and Chemical Toxicology · doi:10.1016/j.fct.2020.111911 · Cited by 28

A functional outside-in signaling network of proteoglycans and matrix molecules regulating autophagy

Neill, T., Kapoor, A., Xie, C., Buraschi, S., & Iozzo, R. V. (2021) · Matrix Biology · doi:10.1016/j.matbio.2021.04.001 · Cited by 29

Hepatoprotective effect of anemoside B4 against sepsis-induced acute liver injury through modulating the mTOR/p70S6K-mediated autophagy

Liang, P., & He, L. (2021) · Chemico-Biological Interactions · doi:10.1016/j.cbi.2021.109534 · Cited by 29

Proteasome inhibition by bortezomib parallels a reduction in head and neck cancer cells growth, and an increase in tumor-infiltrating immune cells

Benvenuto, M., Ciuffa, S., Focaccetti, C., Sbardella, D., Fazi, S., Scimeca, M., Tundo, G. R., Barillari, G., Segni, M., Bonanno, E., et al. (2021) · Scientific Reports · doi:10.1038/s41598-021-98450-6 · Cited by 30

Human platelets display dysregulated sepsis-associated autophagy, induced by altered LC3 protein-protein interaction of the Vici-protein EPG5

Schwertz, H., Rowley, J. W., Portier, I., Middleton, E. A., Tolley, N. D., Campbell, R. A., Eustes, A. S., Chen, K., & Rondina, M. T. (2021) · Autophagy · doi:10.1080/15548627.2021.1990669 · Cited by 29

DA-1241, a Novel GPR119 Agonist, Improves Hyperglycaemia by Inhibiting Hepatic Gluconeogenesis and Enhancing Insulin Secretion in Diabetic Mice

Kim, Y., Lee, S. W., Wang, H., Kim, R.-H., Park, H. K., Lee, H., & Kang, E. S. (2022) · Diabetes & Metabolism Journal · doi:10.4093/dmj.2021.0056 · Cited by 28

HIF‐1α Ameliorates Diabetic Neuropathic Pain via Parkin‐Mediated Mitophagy in a Mouse Model

He, J., Qin, Z., Chen, X., He, W., Li, D., Zhang, L., Le, Y., Xiong, Q., Zhang, B., & Wang, H. (2022) · BioMed Research International · doi:10.1155/2022/5274375 · Cited by 29

Staufen Impairs Autophagy in Neurodegeneration

Paul, S., Dansithong, W., Gandelman, M., Figueroa, K. P., Zu, T., Ranum, L. P. W., Scoles, D. R., & Pulst, S. M. (2022) · Annals of Neurology · doi:10.1002/ana.26515 · Cited by 32

Fisetin induces apoptosis in colorectal cancer cells by suppressing autophagy and down‐regulating nuclear factor erythroid 2‐related factor 2 (Nrf2)

Pandey, A., & Trigun, S. K. (2023) · Journal of Cellular Biochemistry · doi:10.1002/jcb.30447 · Cited by 28

Novel Sites of Neuroprotective Action of Dimebon (Latrepirdine)

Ustyugov, A. A., Shevtsova, E. F., & Бачурин, С. О. (2015) · Molecular Neurobiology · doi:10.1007/s12035-015-9249-4 · Cited by 28

Increased autophagic activity in senescent human dental pulp cells

Li, L., Zhu, Y., Jiang, L., & Peng, W. (2012) · International Endodontic Journal · doi:10.1111/j.1365-2591.2012.02064.x · Cited by 29

Autophagy as a mechanism for myolysis of cardiomyocytes in mitral regurgitation

Chen, M., Chang, J., Wang, Y., Liu, W., Ho, W., & Chang, H. (2010) · European Journal of Clinical Investigation · doi:10.1111/j.1365-2362.2010.02410.x · Cited by 28

Autophagy‐Induced Apoptosis in Lung Cancer Cells by a Novel Digitoxin Analog

Kulkarni, Y. M., Kaushik, V., Azad, N., Wright, C. A., Rojanasakul, Y., O'Doherty, G. A., & Iyer, A. K. V. (2015) · Journal of Cellular Physiology · doi:10.1002/jcp.25129 · Cited by 28

Induction of autophagic cell death of glioma-initiating cells by cell-penetrating d-isomer peptides consisting of Pas and the p53 C-terminus

Ueda, Y., Wei, F., Hide, T.-I., Michiue, H., Takayama, K., Kaitsuka, T., Nakamura, H., Makino, K., Kuratsu, J., Futaki, S., et al. (2012) · Biomaterials · doi:10.1016/j.biomaterials.2012.09.003 · Cited by 28

Age effect on myocellular remodeling: Response to exercise and nutrition in humans

Irving, B. A., Robinson, M. M., & Nair, K. S. (2011) · Ageing Research Reviews · doi:10.1016/j.arr.2011.11.001 · Cited by 31

Cytoplasmic vacuolization responses to cytopathic bovine viral diarrhoea virus

Birk, A. V., Dubovi, E. J., Cohen‐Gould, L., Donis, R. O., & Szeto, H. H. (2007) · Virus Research · doi:10.1016/j.virusres.2007.10.017 · Cited by 28

Accumulation of Autophagosomes in Semliki Forest Virus-Infected Cells Is Dependent on Expression of the Viral Glycoproteins

Eng, K. E., Panas, M. D., Murphy, D., Hedestam, G. B. K., & McInerney, G. M. (2012) · Journal of Virology · doi:10.1128/jvi.06581-11 · Cited by 28

Aerobic training as an adjunctive therapy to enzyme replacement in Pompe disease

Nilsson, M. I., Samjoo, I. A., Hettinga, B. P., Koeberl, D. D., Zhang, H., Hawke, T. J., Nissar, A. A., Ali, T., Brandt, L., Ansari, M. U., et al. (2012) · Molecular Genetics and Metabolism · doi:10.1016/j.ymgme.2012.09.010 · Cited by 28

Autophagy and the (Pro)renin Receptor

Binger, K. J., & Müller, D. N. (2013) · Frontiers in Endocrinology · doi:10.3389/fendo.2013.00155 · Cited by 27

Autophagy induced by snakehead fish vesiculovirus inhibited its replication in SSN-1 cell line

Wang, Y., Chen, N., Hegazy, A. M., et al. (2016) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2016.06.019 · Cited by 28

Metformin induces degradation of mTOR protein in breast cancer cells

Alalem, M. A., Ray, A., & Ray, B. K. (2016) · Cancer Medicine · doi:10.1002/cam4.896 · Cited by 27

Analysis of the mechanism of radiation-induced upregulation of mitochondrial abundance in mouse fibroblasts

Yamamori, T., Sasagawa, T., Ichii, O., Hiyoshi, M., Bo, T., Yasui, H., Kon, Y., & Inanami, O. (2016) · Journal of Radiation Research · doi:10.1093/jrr/rrw113 · Cited by 29

Exposure to 835 MHz radiofrequency electromagnetic field induces autophagy in hippocampus but not in brain stem of mice

Kim, J. H., Yu, D.-H., Kim, H., Huh, Y. H., Cho, S., Lee, J.-K., Kim, H., & Kim, H. R. (2017) · Toxicology and Industrial Health · doi:10.1177/0748233717740066 · Cited by 28

Overexpression of EZH2 in conjunctival melanoma offers a new therapeutic target

Cao, J., Pontes, K. C., Heijkants, R. C., Brouwer, N. J., Groenewoud, A., Jordanova, E. S., Marinkovic, M., van Duinen, S. G., Teunisse, A. F. A. S., Verdijk, R. M., et al. (2018) · The Journal of Pathology · doi:10.1002/path.5094 · Cited by 28

Involvement of HuR in the serum starvation induced autophagy through regulation of Beclin1 in breast cancer cell-line, MCF-7

De, S., Das, S., & Sengupta, S. (2019) · Cellular Signalling · doi:10.1016/j.cellsig.2019.05.008 · Cited by 26

A Potent Autophagy Inhibitor (Lys05) Enhances the Impact of Ionizing Radiation on Human Lung Cancer Cells H1299

Čecháková, L., Ondrej, M., Pavlík, V., Jost, P., Čížková, D., Bezrouk, A., Pejchal, J., Amaravadi, R. K., Winkler, J. D., & Tichý, A. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20235881 · Cited by 28

Gartanin induces autophagy through JNK activation which extenuates caspase-dependent apoptosis

Kim, M.-O., Lee, H.-S., Chin, Y., Moon, D., & Ahn, J. (2015) · Oncology Reports · doi:10.3892/or.2015.3948 · Cited by 27

Oxygen–Glucose Deprivation (OGD) Modulates the Unfolded Protein Response (UPR) and Inflicts Autophagy in a PC12 Hypoxia Cell Line Model

Vavilis, T., Delivanoglou, N., Aggelidou, E., Stamoula, Ε., Mellidis, K., Kaidoglou, A., Cheva, A., Pourzitaki, C., Chatzimeletiou, K., Lazou, A., et al. (2015) · Cellular and Molecular Neurobiology · doi:10.1007/s10571-015-0250-2 · Cited by 27

Ursolic acid and resveratrol synergize with chloroquine to reduce melanoma cell viability

Junco, J. J., Mancha, A., Malik, G., Wei, S., Kim, D. J., Liang, H., & Slaga, T. J. (2015) · Melanoma Research · doi:10.1097/cmr.0000000000000137 · Cited by 27

Effects of Furanodiene on 95-D Lung Cancer Cells: Apoptosis, Autophagy and G1 Phase Cell Cycle Arrest

Xu, W., Li, T., Wu, G., Dang, Y., Hao, W., Chen, X., Lu, J., & Wang, Y. (2014) · The American Journal of Chinese Medicine · doi:10.1142/s0192415x14500165 · Cited by 27

Knocking Down HMGB1 Using Dendrimer-Delivered siRNA Unveils Its Key Role in NMDA-Induced Autophagy in Rat Cortical Neurons

Pérez‐Carrión, M. D., & Ceña, V. (2013) · Pharmaceutical Research · doi:10.1007/s11095-013-1049-9 · Cited by 28

AMP-activated protein kinase-dependent autophagy mediated the protective effect of sonic hedgehog pathway on oxygen glucose deprivation-induced injury of cardiomyocytes

Xiao, Q., Yang, Y., Qin, Y. H., He, Y., Chen, K., Zhu, J., Zhang, G., & Luo, J. (2015) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2015.01.006 · Cited by 27

Induction of Forkhead Class box O3a and apoptosis by a standardized ginsenoside formulation, KG-135, is potentiated by autophagy blockade in A549 human lung cancer cells

Yao, C., Chow, J., Chuang, S., et al. (2016) · Journal of Ginseng Research · doi:10.1016/j.jgr.2016.04.003 · Cited by 27

The licorice dietary component isoliquiritigenin chemosensitizes human uterine sarcoma cells to doxorubicin and inhibits cell growth by inducing apoptosis and autophagy via inhibition of m-TOR signaling

Lin, L.-C., Wu, C., Shieh, T., Chen, H.-Y., Huang, T., & Hsia, S. (2017) · Journal of Functional Foods · doi:10.1016/j.jff.2017.03.061 · Cited by 27

Evidence for the link between defective autophagy and inflammation in peripheral blood mononuclear cells of type 2 diabetic patients

Alizadeh, S., Mazloom, H., Sadeghi, A., Emamgholipour, S., Golestani, A., Noorbakhsh, F., Khoshniatnikoo, M., & Meshkani, R. (2018) · Journal of Physiology and Biochemistry · doi:10.1007/s13105-018-0624-2 · Cited by 27

Dysregulation of autophagy in the central nervous system of sheep naturally infected with classical scrapie

López-Pérez, Ó., Otero, A., Filali, H., Sánz-Rubio, D., Toivonen, J. M., Zaragoza, P., Badiola, J. J., Bolea, R., & Martín‐Burriel, I. (2019) · Scientific Reports · doi:10.1038/s41598-019-38500-2 · Cited by 28

Propofol Attenuates α-Synuclein Aggregation and Neuronal Damage in a Mouse Model of Ischemic Stroke

Wang, Y., Tian, D., Wei, C., Cui, V., Wang, H., Zhu, Y., Wu, A., & Yue, Y. (2019) · Neuroscience Bulletin · doi:10.1007/s12264-019-00426-0 · Cited by 27

Autophagy in chronic stress induced atherosclerosis

Li, N., Zhang, R., Xie, X., & Gu, H. (2020) · Clinica Chimica Acta · doi:10.1016/j.cca.2020.01.006 · Cited by 26

Perturbation of PI3K/Akt signaling affected autophagy modulation in dystrophin-deficient myoblasts

Yazid, M. D., & Chen, H.-C. (2021) · Cell Communication and Signaling · doi:10.1186/s12964-021-00785-0 · Cited by 27

Therapeutic evaluation of palbociclib and its compatibility with other chemotherapies for primary and recurrent nasopharyngeal carcinoma

Xue, Z., Lui, V. W. Y., Li, Y., Jia, L., You, C., Li, X., Piao, W., Yuan, H., Khong, P. L., Lo, K. W., et al. (2020) · Journal of Experimental & Clinical Cancer Research · doi:10.1186/s13046-020-01763-z · Cited by 27

Autophagy facilitates type I collagen synthesis in periodontal ligament cells

Nakamura, T., Yamashita, M., Ikegami, K., Suzuki, M., Yanagita, M., Kitagaki, J., Kitamura, M., & Murakami, S. (2021) · Scientific Reports · doi:10.1038/s41598-020-80275-4 · Cited by 32

Phlorizin from sweet tea inhibits the progress of esophageal cancer by antagonizing the JAK2/STAT3 signaling pathway

Jia, Z., Xie, Y., Wu, H., Wang, Z., Li, A., Li, Z., Yang, Z., Zhang, Z., Xing, Z., & Zhang, X. (2021) · Oncology Reports · doi:10.3892/or.2021.8088 · Cited by 27

Effects of intracellular calcium accumulation on proteins encoded by the major genes underlying amyotrophic lateral sclerosis

Marco, G. D., Lomartire, A., Manera, U., Canosa, A., Grassano, M., Casale, F., Fuda, G., Salamone, P., RINAUDO, M. T., Colombatto, S., et al. (2022) · Scientific Reports · doi:10.1038/s41598-021-04267-8 · Cited by 27

Alanyl-Glutamine Protects against Lipopolysaccharide-Induced Liver Injury in Mice via Alleviating Oxidative Stress, Inhibiting Inflammation, and Regulating Autophagy

Hu, J., Ying, H., Zheng, Y., Ma, H., Li, L., & Zhao, Y. (2022) · Antioxidants · doi:10.3390/antiox11061070 · Cited by 27

Nicotinamide Mononucleotide Alleviates Osteoblast Senescence Induction and Promotes Bone Healing in Osteoporotic Mice

Lu, Z., Jiang, L., Lesani, P., Zhang, W., Li, N., Luo, D., Li, Y., Ye, Y., Bian, J., Wang, G., et al. (2022) · The Journals of Gerontology Series A · doi:10.1093/gerona/glac175 · Cited by 30

The R740 S mutation in the V‐ ATP ase a3 subunit results in osteoclast apoptosis and defective early‐stage autophagy

Ochotny, N., Voronov, I., Owen, C., Aubin, J. E., & Manolson, M. F. (2013) · Journal of Cellular Biochemistry · doi:10.1002/jcb.24630 · Cited by 27

Role of oxidative stress in cytotoxicity of grape seed extract in human bladder cancer cells

Raina, K., Tyagi, A., Kumar, D., Agarwal, R., & Agarwal, C. (2013) · Food and Chemical Toxicology · doi:10.1016/j.fct.2013.06.039 · Cited by 27

Suppression of murine experimental autoimmune encephalomyelitis development by 1,25-dihydroxyvitamin D3 with autophagy modulation

Zhen, C. J., Feng, X., Li, Z., Wang, Y., Li, B., Li, L., Quan, M., Wang, G., & Guo, L. (2015) · Journal of Neuroimmunology · doi:10.1016/j.jneuroim.2015.01.012 · Cited by 27

Physiological Difference in Autophagic Flux in Macrophages From 2 Mouse Strains Regulates Cholesterol Ester Metabolism

Robinet, P., Ritchey, B., & Smith, J. D. (2013) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.112.301041 · Cited by 27

Self-Eating: Friend or Foe? The Emerging Role of Autophagy in Idiopathic Pulmonary Fibrosis

Margaritopoulos, G. A., Tsitoura, E., Tzanakis, N., Spandidos, D. A., Siafakas, N. M., Sourvinos, G., & Antoniou, K. M. (2013) · BioMed Research International · doi:10.1155/2013/420497 · Cited by 27

Study of Malformin C, a Fungal Source Cyclic Pentapeptide, as an Anti-Cancer Drug

Wang, J., Jiang, Z., Lam, W., et al. (2015) · PLoS ONE · doi:10.1371/journal.pone.0140069 · Cited by 27

Brain metabolism as a modulator of autophagy in neurodegeneration

Lim, Y., Cho, H., & Kim, E. K. (2016) · Brain Research · doi:10.1016/j.brainres.2016.02.049 · Cited by 27

Salidroside protects cortical neurons against glutamate-induced cytotoxicity by inhibiting autophagy

Yin, W.-Y., Ye, Q., Huang, H., Xia, N., Chen, Y., Zhang, Y., & Qu, Q. (2016) · Molecular and Cellular Biochemistry · doi:10.1007/s11010-016-2749-3 · Cited by 27

(±)-Gossypol induces apoptosis and autophagy in head and neck carcinoma cell lines and inhibits the growth of transplanted salivary gland cancer cells in BALB/ c mice

Benvenuto, M., Mattera, R., Masuelli, L., Taffera, G., Andracchio, O., Tresoldi, I., Lido, P., Giganti, M. G., Godos, J., Modesti, A., et al. (2016) · International Journal of Food Sciences and Nutrition · doi:10.1080/09637486.2016.1236077 · Cited by 27

Proton Pump Inhibitors Display Antitumor Effects in Barrett's Adenocarcinoma Cells

Chueca, E., Apostolova, N., Esplugues, J. V., García-González, M. A., Lanas, Á., & Piazuelo, E. (2016) · Frontiers in Pharmacology · doi:10.3389/fphar.2016.00452 · Cited by 28

Carbon Monoxide Inhibits Islet Apoptosis via Induction of Autophagy

Kim, D., Song, L., Wang, J., Wu, H., Gou, W., Cui, W., Kim, J., & Wang, H. (2017) · Antioxidants and Redox Signaling · doi:10.1089/ars.2016.6979 · Cited by 27

Rapamycin‑induced autophagy attenuates hormone‑imbalance‑induced chronic non‑bacterial prostatitis in rats via the inhibition of NLRP3 inflammasome‑mediated inflammation

Lu, J., Yang, S., Chen, X., Chen, Y., Luo, P., Lin, F., & Zhang, J. (2018) · Molecular Medicine Reports · doi:10.3892/mmr.2018.9683 · Cited by 27

Autophagy links antimicrobial activity with antigen presentation in Langerhans cells

Dang, A. T., Teles, R. M. B., Liu, P. T., Choi, A. W., Legaspi, A. J., Sarno, E. N., Ochoa, M. T., Parvatiyar, K., Cheng, G., Gilliet, M. F., et al. (2019) · JCI Insight · doi:10.1172/jci.insight.126955 · Cited by 28

Modulation of O-GlcNAcylation Regulates Autophagy in Cortical Astrocytes

Rahman, M. A., Hwang, H., Cho, Y., & Rhim, H. (2019) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2019/6279313 · Cited by 26

GSK-3-TSC axis governs lysosomal acidification through autophagy and endocytic pathways

Avrahami, L., Paz, R., Dominko, K., Hecimovic, S. K., Bucci, C., & Eldar-Finkelman, H. (2020) · Cellular Signalling · doi:10.1016/j.cellsig.2020.109597 · Cited by 28

Effects of long-term resistance exercise training on autophagy in rat skeletal muscle of chloroquine-induced sporadic inclusion body myositis

Kwon, I., Lee, Y., Cosío-Lima, L., Cho, J., & Yeom, D.-C. (2015) · Physical Activity and Nutrition · doi:10.5717/jenb.2015.15090710 · Cited by 27

Autophagy and enhanced chemosensitivity in experimental pancreatic cancers induced by noninvasive radiofrequency field treatment

Koshkina, N. V., Briggs, K. L., Palalon, F., & Curley, S. A. (2013) · Cancer · doi:10.1002/cncr.28453 · Cited by 26

Autophagy in skin wounds: a novel marker for vital reactions

Kimura, A., Ishida, Y., Nosaka, M., Shiraki, M., Hama, M., Kawaguchi, T., Kuninaka, Y., Shimada, E., Yamamoto, H., Takayasu, T., et al. (2015) · International Journal of Legal Medicine · doi:10.1007/s00414-015-1168-4 · Cited by 27

BNIP3 protects HepG2 cells against etoposide-induced cell death under hypoxia by an autophagy-independent pathway

Cosse, J.-P., Rommelaere, G., Ninane, N., Arnould, T., & Michiels, C. (2010) · Biochemical Pharmacology · doi:10.1016/j.bcp.2010.07.009 · Cited by 26

Chronic activation of PPARα with fenofibrate reduces autophagic proteins in the liver of mice independent of FGF21

Jo, E., Li, S., Liang, Q., Zhang, X., Wang, H., Herbert, T. P., Jenkins, T. A., Xu, A., & Ye, J. (2017) · PLoS ONE · doi:10.1371/journal.pone.0173676 · Cited by 26

Induced pluripotent stem cell-based modeling of neurodegenerative diseases: a focus on autophagy

Jungverdorben, J., Till, A., & Brüstle, O. (2017) · Journal of Molecular Medicine · doi:10.1007/s00109-017-1533-5 · Cited by 27

Trehalose alleviates oxidative stress-mediated liver injury and Mallory-Denk body formation via activating autophagy in mice

Honma, Y., Sato‐Morita, M., Katsuki, Y., et al. (2020) · Medical Molecular Morphology · doi:10.1007/s00795-020-00258-2 · Cited by 26

Neuroprotective Effects of Curcumin in Methamphetamine-Induced Toxicity

Ryskalin, L., Puglisi‐Allegra, S., Lazzeri, G., Biagioni, F., Busceti, C. L., Balestrini, L., Fornasiero, A., Leone, S., Pompili, E., Ferrucci, M., et al. (2021) · Molecules · doi:10.3390/molecules26092493 · Cited by 29

Cerium Oxide Nanoparticles Alleviate Hepatic Fibrosis Phenotypes In Vitro

Boey, A., Leong, S. Q., Bhave, S., & Ho, H. K. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms222111777 · Cited by 26

CFTR Modulators Restore Acidification of Autophago-Lysosomes and Bacterial Clearance in Cystic Fibrosis Macrophages

Badr, A., Eltobgy, M. M., Krause, K., Hamilton, K., Estfanous, S. Z. K., Daily, K. P., Khweek, A. A., Hegazi, A., Anne, M. N. K., Carafice, C., et al. (2022) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2022.819554 · Cited by 27

Autophagy Signaling by Neural-Induced Human Adipose Tissue-Derived Stem Cell-Conditioned Medium during Rotenone-Induced Toxicity in SH-SY5Y Cells

Ramalingam, M., Jeong, H., Hwang, J., Cho, H., Kim, B. C., Kim, E., & Jang, S. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23084193 · Cited by 28

Natural Compounds Targeting the Autophagy Pathway in the Treatment of Colorectal Cancer

Du, Y.-X., Mamun, A. A., Lü, A., & Zhang, H. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24087310 · Cited by 25

The phospholipid transporter PITPNC1 links KRAS to MYC to prevent autophagy in lung and pancreatic cancer

Entrialgo‐Cadierno, R., Cueto‐Ureña, C., Welch, C., Feliu, I., Macaya, I., Vera, L., Morales, X., Michelina, S. V., Scaparone, P., López, I., et al. (2023) · Molecular Cancer · doi:10.1186/s12943-023-01788-w · Cited by 25

Active autophagy but not lipophagy in macrophages with defective lipolysis

Goeritzer, M., Vujić, N., Schlager, S., Chandak, P. G., Korbelius, M., Gottschalk, B., Leopold, C., Obrowsky, S., Rainer, S., Doddapattar, P., et al. (2015) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2015.06.005 · Cited by 27

Potential role of acid ceramidase in conversion of cytostatic to cytotoxic end-point in pancreatic cancer cells

Morad, S. A. F., Messner, M. C., Levin, J. C., et al. (2012) · Cancer Chemotherapy and Pharmacology · doi:10.1007/s00280-012-2050-4 · Cited by 26

HMGB1 translocation is involved in the transformation of autophagy complexes and promotes chemoresistance in leukaemia

KONG, Q., Xu, L., XU, W., Fang, J., & Xu, H. (2015) · International Journal of Oncology · doi:10.3892/ijo.2015.2985 · Cited by 26

Growth inhibitory effects of vitamin K2 on colon cancer cell lines via different types of cell death including autophagy and apoptosis

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Calorie restriction increases telomerase activity, enhances autophagy, and improves diastolic dysfunction in diabetic rat hearts

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miR-1273g-3p participates in acute glucose fluctuation-induced autophagy, dysfunction, and proliferation attenuation in human umbilical vein endothelial cells

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Methylglyoxal at metronomic doses sensitizes breast cancer cells to doxorubicin and cisplatin causing synergistic induction of programmed cell death and inhibition of stemness

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Cellular toxicity of dietary trans fatty acids and its correlation with ceramide and diglyceride accumulation

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Chapter 14 Autophagy in Lung Cancer

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Acute exercise rapidly activates hepatic mitophagic flux

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Targeted Degradation of Alpha-Synuclein by Autophagosome-Anchoring Chimera Peptides

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Erbin accelerates TFEB-mediated lysosome biogenesis and autophagy and alleviates sepsis-induced inflammatory responses and organ injuries

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Molecular mechanisms in regulation of autophagy and apoptosis in view of epigenetic regulation of genes and involvement of liquid-liquid phase separation

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Impaired neuronal macroautophagy in the prelimbic cortex contributes to comorbid anxiety-like behaviors in rats with chronic neuropathic pain

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Novel autophagy inducers by accelerating lysosomal clustering against Parkinson’s disease

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Irisin attenuates acute glaucoma-induced neuroinflammation by activating microglia-integrin αVβ5/AMPK and promoting autophagy.

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Dysregulation of autophagy during photoaging reduce oxidative stress and inflammatory damage caused by UV

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Emodin Inhibits NLRP3 Inflammasome Activation and Protects Against Sepsis via Promoting FUNDC1-Mediated Mitophagy

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BRCA1 deficiency induces protective autophagy to mitigate stress and provides a mechanism for BRCA1 haploinsufficiency in tumorigenesis

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Aggravation of acute kidney injury by mPGES-2 down regulation is associated with autophagy inhibition and enhanced apoptosis

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LSD1 negatively regulates autophagy through the mTOR signaling pathway in ovarian cancer cells

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Varicella-zoster virus inhibits autophagosome-lysosome fusion and the degradation stage of mTOR-mediated autophagic flux

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cAMP-mediated autophagy inhibits DNA damage-induced death of leukemia cells independent of p53

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Junín Virus Promotes Autophagy To Facilitate the Virus Life Cycle

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An Update on Autophagy in Prion Diseases

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Autophagy in cancer biology and therapy

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Is Selective Autophagy Distinct from Starvation-Induced Autophagy?

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Bnip3 interacts with LC3 to induce selective removal of endoplasmic reticulum and mitochondria via autophagy

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Self-consumption: the interplay of autophagy and apoptosis

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Posttranslational Modifications of Autophagy-related Proteins

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