How to Interpret LC3 Immunoblotting

LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing.

Kabeya, Y., Mizushima, N., Ueno, T., Yamamoto, A., Kirisako, T., Noda, T., Kominami, E., Ohsumi, Y., & Yoshimori, T. (2000) · The EMBO Journal · doi:10.1093/emboj/19.21.5720 · Cited by 6,605

p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death

Bjørkøy, G., Lamark, T., Brech, A., Outzen, H., Perander, M., Øvervatn, A., Stenmark, H., & Johansen, T. (2005) · The Journal of Cell Biology · doi:10.1083/jcb.200507002 · Cited by 3,276

The role of autophagy during the early neonatal starvation period

Kuma, A., Hatano, M., Matsui, M., Yamamoto, A., Nakaya, H., Yoshimori, T., Ohsumi, Y., Tokuhisa, T., & Mizushima, N. (2004) · Nature · doi:10.1038/nature03029 · Cited by 2,865

The role of autophagy in cardiomyocytes in the basal state and in response to hemodynamic stress

Nakai, A., Yamaguchi, O., Takeda, T., Higuchi, Y., Hikoso, S., Taniike, M., Omiya, S., Mizote, I., Matsumura, Y., Asahi, M., et al. (2007) · Nature Medicine · doi:10.1038/nm1574 · Cited by 1,520

LC3, GABARAP and GATE16 localize to autophagosomal membrane depending on form-II formation

Kabeya, Y., Mizushima, N., Yamamoto, A., Oshitani-Okamoto, S., Ohsumi, Y., & Yoshimori, T. (2004) · Journal of Cell Science · doi:10.1242/jcs.01131 · Cited by 1,394

Bafilomycin A1 prevents maturation of autophagic vacuoles by inhibiting fusion between autophagosomes and lysosomes in rat hepatoma cell line, H-4-II-E cells

Yamamoto, A., Tagawa, Y., Yoshimori, T., Moriyama, Y., Masaki, R., & Tashiro, Y. (1998) · Cell Structure and Function · doi:10.1247/csf.23.33 · Cited by 1,312

Lysosomal turnover, but not a cellular level, of endogenous LC3 is a marker for autophagy

Tanida, I., Minematsu-Ikeguchi, N., Ueno, T., & Kominami, E. (2005) · Autophagy · doi:10.4161/auto.1.2.1697 · Cited by 1,108

The pre‐autophagosomal structure organized by concerted functions of APG genes is essential for autophagosome formation

Suzuki, K., Kirisako, T., Kamada, Y., Mizushima, N., Noda, T., & Ohsumi, Y. (2001) · The EMBO Journal · doi:10.1093/emboj/20.21.5971 · Cited by 1,060

Role of autophagy in temozolomide-induced cytotoxicity for malignant glioma cells

Kanzawa, T., Germano, I. M., Komata, T., Ito, H., Kondo, Y., & Kondo, S. (2004) · Cell Death and Differentiation · doi:10.1038/sj.cdd.4401359 · Cited by 995

Methods for monitoring autophagy

Mizushima, N. (2004) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/j.biocel.2004.02.005 · Cited by 899

The protective effects of Esculentoside A through AMPK in the triple transgenic mouse model of Alzheimer's disease

He, Z., Zhang, H., Li, X., Tu, S., Wang, Z., Han, S., Du, X., Shen, L., Li, N., & Liu, Q. (2022) · Phytomedicine · doi:10.1016/j.phymed.2022.154555 · Cited by 12

Macronutrient Deprivation Modulates Antigen Trafficking and Immune Recognition through HSC70 Accessibility

Deffit, S. N., & Blum, J. S. (2015) · The Journal of Immunology · doi:10.4049/jimmunol.1402472 · Cited by 11

The Chemotherapeutic Agents XK469 (2-{4-[(7-Chloro-2-quinoxalinyl)oxy]phenoxy}propionic acid) and SH80 (2-{4-[(7-Bromo-2-quinolinyl)oxy]phenoxy}propionic acid) Inhibit Cytokinesis and Promote Polyploidy and Induce Senescence

Reiners, J. J., Kleinman, M., Joiakim, A., et al. (2008) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.108.144808 · Cited by 11

Parkin Overexpression Ameliorates PrP106–126-Induced Neurotoxicity via Enhanced Autophagy in N2a Cells

Khan, S. H., Zhao, D., Shah, S. Z. A., Hassan, M. F., Zhu, T., Song, Z., Zhou, X., & Yang, L. (2016) · Cellular and Molecular Neurobiology · doi:10.1007/s10571-016-0407-7 · Cited by 12

Suppressed nuclear envelope proteins activate autophagy of vascular smooth muscle cells during cyclic stretch application

Li, H., Liu, J.-T., Chen, Y., Wang, W., Han, Y., Yao, Q., & Qi, Y. (2020) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2020.118855 · Cited by 11

The role of TIGAR in nervous system diseases

Huang, B., Lang, X., & Li, X. (2022) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2022.1023161 · Cited by 11

MicroRNA miR-378-3p is a novel regulator of endothelial autophagy and function

Bu, S., Joseph, J., Nguyen, H. C., Ehsan, M., Rasheed, B., Singh, A., Qadura, M., Frisbee, J. C., & Singh, K. K. (2022) · Journal of Molecular and Cellular Cardiology Plus · doi:10.1016/j.jmccpl.2022.100027 · Cited by 10

Autophagy regulates anti-angiogenic property of lenvatinib in thyroid cancer.

Xue, L., Gong, Z., Vlantis, A. C., Chan, J. Y. H., Meehan, K. L., van Hasselt, C. A., Li, D., Zeng, X., Wei, M., Tong, M. C. F., et al. (2023) · PubMed Central · Cited by 11

Blocking insulin-like growth factor 1 receptor signaling pathway inhibits neuromuscular junction regeneration after botulinum toxin-A treatment

Ishihara, H., Otani, Y., Tanaka, K., Miyajima, H., Ngo, H. X., & Fujitani, M. (2023) · Cell Death and Disease · doi:10.1038/s41419-023-06128-w · Cited by 11

Transcription factor EB-mediated autophagy affects cell migration and inhibits apoptosis to promote endometriosis

Chen, Q., Zhou, Y., Yu, M., Zhu, S., Sun, J., Du, W., Chen, Z., Tao, J., Feng, X., Zhang, Q., et al. (2024) · APOPTOSIS · doi:10.1007/s10495-024-01939-4 · Cited by 10

Promoting collateral formation in type 2 diabetes mellitus using ultra-small nanodots with autophagy activation and ROS scavenging

Wang, Y., Li, F., Mao, L., Liu, Y., Chen, S., Liu, J., Huang, K. Q., Chen, Q., Wu, J., Lu, L., et al. (2024) · Journal of Nanobiotechnology · doi:10.1186/s12951-024-02357-z · Cited by 10

Role of canonical and noncanonical autophagy pathways in shaping the life journey of B cells

Wang, Y., Wu, L., & Kaer, L. V. (2024) · Frontiers in Immunology · doi:10.3389/fimmu.2024.1426204 · Cited by 13

A novel strategy to enhance inhibition of Hela cervical cancer by combining Lentinus β-glucan and autophagic flux blockage

Hu, S., Meng, Y., Guo, L., et al. (2024) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2024.136309 · Cited by 10

KIF1C facilitates retrograde transport of lysosomes through Hook3 and dynein

Saji, T., Endo, M., Okada, Y., Minami, Y., & Nishita, M. (2024) · Communications Biology · doi:10.1038/s42003-024-07023-6 · Cited by 10

Small molecule modulation of p75NTR engages the autophagy-lysosomal pathway and reduces huntingtin aggregates in cellular and mouse models of Huntington's disease

Simmons, D. A., Alexander, N., Cao, G., Rippin, I., Lugassy, Y., Eldar-Finkelman, H., & Longo, F. M. (2024) · Neurotherapeutics · doi:10.1016/j.neurot.2024.e00495 · Cited by 10

PTPσ-mediated PI3P regulation modulates neurodegeneration in C9ORF72-ALS/FTD

Zhang, Z., Fu, X., Wright, N., Wang, W., Ye, Y., Asbury, J., Li, Y., Zhu, C., Wu, R., Wang, S., et al. (2025) · Neuron · doi:10.1016/j.neuron.2025.02.005 · Cited by 9

Autophagy and Respiratory Viruses: Mechanisms, Viral Exploitation, and Therapeutic Insights

Aligolighasemabadi, F., Kiełbowski, K., Bakinowska, E., Sadeghdoust, M., Coombs, K. M., Mehrbod, P., & Ghavami, S. (2025) · Cells · doi:10.3390/cells14060418 · Cited by 13

Rapamycin reduces mineral density and promotes beneficial vascular remodeling in a murine model of severe medial arterial calcification

Behzadi, P., Wendling, A. A., Cuevas, R. A., Crane, A., Chu, C. C., Moorhead, W. J., Wong, R., Brown, M. J., Tamakloe, J., Suresh, S., et al. (2025) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00530.2024 · Cited by 11

Opposite Effects of Two Human ATG10 Isoforms on Replication of a HCV Sub-genomic Replicon Are Mediated via Regulating Autophagy Flux in Zebrafish

Li, Y., Zhang, M., & Zhang, J. (2018) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2018.00109 · Cited by 10

3-methyadenine attenuates chloroform-induced hepatotoxicity via autophagy activation

Wang, L., Li, X., & Cai, C. H. E. N. (2018) · Biomedical Research · doi:10.2220/biomedres.39.87 · Cited by 10

Identification of RNA aptamer which specifically interacts with PtdIns(3)P

Donia, T., Bala, J., Suizu, F., Hirata, N., Tanaka, T., Ishigaki, S., Pranzatelli, T. J. F., Nio‐Kobayashi, J., Iwanaga, T., Chiorini, J. A., et al. (2019) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2019.07.034 · Cited by 11

Traumatic brain injury in the presence of Aβ pathology affects neuronal survival, glial activation and autophagy

Streubel-Gallasch, L., Zyśk, M., Beretta, C., & Erlandsson, A. (2021) · Scientific Reports · doi:10.1038/s41598-021-02371-3 · Cited by 11

The autophagy response during adipogenesis of primary cultured rainbow trout (Oncorhynchus mykiss) adipocytes

Riera‐Heredia, N., Lutfi, E., Balbuena-Pecino, S., Vélez, E. J., Dias, K., Beaumatin, F., Gutiérrez, J., Seiliez, I., Capilla, E., & Navarro, I. (2021) · Comparative Biochemistry and Physiology Part B Biochemistry and Molecular Biology · doi:10.1016/j.cbpb.2021.110700 · Cited by 10

Loss of αA or αB-Crystallin Accelerates Photoreceptor Cell Death in a Mouse Model of P23H Autosomal Dominant Retinitis Pigmentosa

Wang, T., Yao, J., Jia, L., Fort, P. E., & Zacks, D. N. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms23010070 · Cited by 10

Glycosylation-Dependent Induction of Programmed Cell Death in Murine Adenocarcinoma Cells

Parshenkov, A., & Hennet, T. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.797759 · Cited by 10

Casein kinase I inhibitor D4476 influences autophagy and apoptosis in chloroquine-induced adult retinal pigment epithelial-19 cells

Hoang, A. T. N., Lee, H., & Lee, S.-J. (2022) · Experimental Eye Research · doi:10.1016/j.exer.2022.109004 · Cited by 11

Recruitment of LC3 by Campylobacter jejuni to Bacterial Invasion Site on Host Cells via the Rac1-Mediated Signaling Pathway

Fukushima, S., Shimohata, T., Inoue, Y., Kido, J., Uebanso, T., Mawatari, K., & Takahashi, A. (2022) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2022.829682 · Cited by 10

Beclin1 Deficiency Suppresses Epileptic Seizures

Yang, M., Lin, P., Jing, W., Guo, H., Chen, H., Chen, Y., Guo, Y., Gu, Y., He, M., Wu, J., et al. (2022) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2022.807671 · Cited by 9

In vitro evaluation of Resveratrol as a potential pre-exposure prophylactic drug against Trypanosoma cruzi infection

Rodríguez, M. E., Tekiel, V., & Campo, V. A. (2022) · International Journal for Parasitology Drugs and Drug Resistance · doi:10.1016/j.ijpddr.2022.08.003 · Cited by 11

Trans‐gnetin H isolated from the seeds of Paeonia species induces autophagy via inhibiting mTORC1 signalling through AMPK activation

Xia, C., Wang, G., Chen, L., Geng, H., Yao, J., Bai, Z., & Deng, L. (2022) · Cell Proliferation · doi:10.1111/cpr.13360 · Cited by 10

Celecoxib activates autophagy by inhibiting the mTOR signaling pathway and prevents apoptosis in nucleus pulposus cells

Chen, W., Yasen, M., Wang, H., Zhuang, C., Wang, Z., Lu, S., Jiang, L., & Lin, H. R. (2022) · BMC Pharmacology and Toxicology · doi:10.1186/s40360-022-00633-y · Cited by 10

Formosanin C suppresses cancer cell proliferation and migration by impeding autophagy machinery

Chu, M., Lin, P., Liu, Y., et al. (2023) · The Kaohsiung Journal of Medical Sciences · doi:10.1002/kjm2.12658 · Cited by 10

An update on the role of thioredoxin-interacting protein in diabetic kidney disease: A mini review

Sun, H. Q., Sun, R., Hua, Y., Lu, Q., & Shao, X. (2023) · Frontiers in Medicine · doi:10.3389/fmed.2023.1153805 · Cited by 10

Autophagy Inhibition with Chloroquine Increased Pro-Apoptotic Potential of New Aziridine-Hydrazide Hydrazone Derivatives against Glioblastoma Cells

Witusik‐Perkowska, M., Głowacka, P., Pieczonka, A. M., Świderska, E., Pudlarz, A. M., Rachwalski, M., Szymańska, J., Zakrzewska, M., Jaskólski, D. J., & Szemraj, J. (2023) · Cells · doi:10.3390/cells12141906 · Cited by 10

Three consecutive cytosolic glycolysis enzymes modulate autophagic flux

Lee, D., Choi, I., Park, S. J., et al. (2023) · PLANT PHYSIOLOGY · doi:10.1093/plphys/kiad439 · Cited by 10

Shikonin promotes hypertrophic scar repair by autophagy of hypertrophic scar-derived fibroblasts

Zhang, Q., Wang, M., Deng, X., et al. (2023) · Acta Cirúrgica Brasileira · doi:10.1590/acb384623 · Cited by 10

Intimacy and a deadly feud: the interplay of autophagy and apoptosis mediated by amino acids

Wu, Z., Hu, C.-A. A., Wu, G., Zhaorigetu, S., Chand, H. S., Sun, K., Ji, Y. S., Wang, B., Dai, Z., Walton, B. L., et al. (2015) · Amino Acids · doi:10.1007/s00726-015-2084-0 · Cited by 10

Quantitative indices of autophagy activity from minimal models

Han, K., Kim, J., & Choi, M. Y. (2014) · Theoretical Biology and Medical Modelling · doi:10.1186/1742-4682-11-31 · Cited by 10

Impaired glucose tolerance attenuates bone accrual by promoting the maturation of osteoblasts: Role of Beclin1-mediated autophagy

Rendina-Ruedy, E., Graef, J. L., Lightfoot, S. A., Ritchey, J. W., Clarke, S. L., Lucas, E. A., & Smith, B. J. (2016) · Bone Reports · doi:10.1016/j.bonr.2016.08.001 · Cited by 10

Exposure to BDE-153 induces autophagy in HepG2 cells

Pereira, L. C., Duarte, F. V., Varela, A. T. I. F., Rolo, A. P., Palmeira, C. M., & Dorta, D. J. (2017) · Toxicology in Vitro · doi:10.1016/j.tiv.2017.04.005 · Cited by 10

Effects of Rapid or Slow Body Weight Reduction on Intramuscular Protein Degradation Pathways During Equivalent Weight Loss on Rats

Nonaka, Y., Urashima, S., INAI, M., Nishimura, S., Higashida, K., & Terada, S. (2017) · Physiological Research · doi:10.33549/physiolres.933502 · Cited by 10

Tetrandrine Increases the Sensitivity of Human Lung Adenocarcinoma PC14 Cells to Gefitinib by Lysosomal Inhibition

Sato, E., OHTA, S., KAWAKAMI, K., IKEDA, M., Takahashi, T., Kobayashi, S., & Nomura, M. (2019) · Anticancer Research · doi:10.21873/anticanres.13874 · Cited by 10

Hormonal Regulation of Autophagy in Thyroid PCCL3 Cells and the Thyroids of Male Mice

Kurashige, T., Nakajima, Y., Shimamura, M. I., Yamada, M., & Nagayama, Y. (2020) · Journal of the Endocrine Society · doi:10.1210/jendso/bvaa054 · Cited by 10

Cucurbitacin E Induces Autophagy-Involved Apoptosis in Intestinal Epithelial Cells

Song, H., Sui, H., Zhang, Q., Wang, P., & Wang, F. (2020) · Frontiers in Physiology · doi:10.3389/fphys.2020.01020 · Cited by 10

Effects of acute and chronic strength training on skeletal muscle autophagy in frail elderly men and women

Aas, S. N., Tømmerbakke, D., Godager, S., Nordseth, M., Armani, A., Sandri, M., Benestad, H. B., & Raastad, T. (2020) · Experimental Gerontology · doi:10.1016/j.exger.2020.111122 · Cited by 10

Autophagy Activated by Peroxiredoxin of Entamoeba histolytica

Li, X., Zhang, Y., Zhao, Y., Qiao, K., Feng, M., Zhou, H., Tachibana, H., & Cheng, X. (2020) · Cells · doi:10.3390/cells9112462 · Cited by 10

A LysR Transcriptional Regulator Manipulates Macrophage Autophagy Flux During Brucella Infection

Zhang, L., Yu, S., Ning, X., et al. (2022) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2022.858173 · Cited by 10

Upregulation of the EGFR/MEK1/MAPK1/2 signaling axis as a mechanism of resistance to antiestrogen‑induced BimEL dependent apoptosis in ER+ breast cancer cells

Hagan, M. L., Mander, S., Joseph, C., et al. (2022) · International Journal of Oncology · doi:10.3892/ijo.2022.5468 · Cited by 10

The CNC-family transcription factor Nrf3 coordinates the melanogenesis cascade through macropinocytosis and autophagy regulation

Waku, T., Nakada, S., Masuda, H., Sumi, H., Wada, A., Hirose, S., Aketa, I., & Kobayashi, A. (2022) · Cell Reports · doi:10.1016/j.celrep.2022.111906 · Cited by 10

Impaired Autophagic Clearance with a Gain-of-Function Variant of the Lysosomal Cl−/H+ Exchanger ClC-7

Bose, S., de Heus, C., Kennedy, M. E., Wang, F., Jentsch, T. J., Klumperman, J., & Stauber, T. (2023) · Biomolecules · doi:10.3390/biom13121799 · Cited by 13

Reduced expression of SM22 is correlated with low autophagy activity in human colorectal cancer

Xie, X., Liu, Y.-B., Liu, Y., Du, B.-L., Yang, L., Han, M., & Li, B. (2013) · Pathology - Research and Practice · doi:10.1016/j.prp.2013.02.007 · Cited by 10

A physiological increase in insulin suppresses muscle-specific ubiquitin ligase gene activation in fetal sheep with sustained hypoglycemia

Brown, L. D., Wesolowski, S. R., O'Meara, M. C., Lavezzi, J. R., & Rozance, P. J. (2014) · Physiological Reports · doi:10.14814/phy2.12045 · Cited by 10

Calreticulin Ameliorates Hypoxia/Reoxygenation-Induced Human Microvascular Endothelial Cell Injury By Inhibiting Autophagy

Wang, Y., Tao, T., Song, D., & Liu, X. (2017) · Shock · doi:10.1097/shk.0000000000000905 · Cited by 10

Efficient lysis of B-chronic lymphocytic leukemia cells by the plant-derived sesquiterpene alcohol α-bisabolol, a dual proapoptotic and antiautophagic agent

Rigo, A., Ferrarini, I., Bonalumi, A., et al. (2018) · Oncotarget · doi:10.18632/oncotarget.25398 · Cited by 10

PromISR-6, a Guanabenz Analogue, Improves Cellular Survival in an Experimental Model of Huntington’s Disease

Sundaram, J. R., Wu, Y., Lee, I. C. J., George, S. E., Hota, M., Ghosh, S., Kesavapany, S., Ahmed, M., Tan, E., & Shenolikar, S. (2019) · ACS Chemical Neuroscience · doi:10.1021/acschemneuro.9b00185 · Cited by 11

Autophagy inhibition enhances anti‐pituitary adenoma effect of tetrandrine

Lyu, L., Hu, Y., Yin, S., Wang, L., Feng, Y., Wang, M., Zhou, Y., Ma, W., Chen, C., Jiang, Y., et al. (2021) · Phytotherapy Research · doi:10.1002/ptr.7117 · Cited by 10

The Autophagy Inhibitor Chloroquine, Alone or in Combination with mTOR Inhibitors, Displays Anti-Tumor Effects in In Vitro and In Vivo Lung Carcinoid Models

Knigin, A., Avniel-Polak, S., Leibowitz, G., Oleinikov, K., Gross, D. J., & Grozinsky‐Glasberg, S. (2021) · Cancers · doi:10.3390/cancers13246327 · Cited by 11

Growth hormone remodels the 3D-structure of the mitochondria of inflammatory macrophages and promotes metabolic reprogramming

Palacios, B. S., Villares, R., Lucas, P., Rodrı́guez-Frade, J. M., Cayuela, A., Piccirillo, J., Lombardía, M., Gestoso, D. D., Fernández-García, M., Risco, C., et al. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1200259 · Cited by 10

Oncolytic vaccinia virus harboring aphrocallistes vastus lectin exerts anti-tumor effects by directly oncolysis and inducing immune response through enhancing ROS in human ovarian cancer

Zhang, G., Wang, Q., Yuan, R., et al. (2024) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2024.150355 · Cited by 9

CARMIL1-AA selectively inhibits macropinocytosis while sparing autophagy

Lim, R. M., Lu, A., Chuang, B. M., Anaraki, C., Chu, B., Halbrook, C. J., & Edinger, A. L. (2024) · Molecular Biology of the Cell · doi:10.1091/mbc.e24-09-0434 · Cited by 9

Fangchinoline eliminates intracellular Salmonella by enhancing lysosomal function via the AMPK-mTORC1-TFEB axis

He, M., Wu, H., Xu, T., Zhao, Y., Wang, Z., & Liu, Y. (2025) · Journal of Advanced Research · doi:10.1016/j.jare.2025.01.015 · Cited by 10

Fasudil inhibits α-synuclein aggregation through ROCK-inhibition-mediated mechanisms

Lage, L., Rodriguez-Perez, A. I., Labandeira-García, J. L., & Dominguez‐Meijide, A. (2025) · Neurotherapeutics · doi:10.1016/j.neurot.2025.e00544 · Cited by 9

A therapeutic strategy integrating ultrasound-guided microwave ablation with nanocomposite hydrogels to enhance autophagy and suppress tumor growth in hepatocellular carcinoma

Duan, Y., Ding, L., Meng, X., Lin, J., Fu, H., Zhu, Y., Zhu, Y., Cao, J., Hu, J., Dong, Y., et al. (2025) · Acta Biomaterialia · doi:10.1016/j.actbio.2025.04.032 · Cited by 9

The Transcription Axes ERK-Elk1, JNK-cJun, and JAK-STAT Promote Autophagy Activation and Proteasome Inhibitor Resistance in Prostate Cancer Cells

Kalampounias, G., Zafeiropoulou, K., Androutsopoulou, T., Alexis, S., Symeonidis, A. S., & Katsoris, P. (2025) · Current Issues in Molecular Biology · doi:10.3390/cimb47050352 · Cited by 9

TNF-α impairs platelet function by inhibiting autophagy and disrupting metabolism via syntaxin 17 downregulation

Rojas-Sánchez, G., Calzada-Martinez, J., McMahon, B. J., Petrey, A. C., Dveksler, G. S., Espino-Solís, G. P., Esparza, O., Hernandez, G., Le, D., Wartchow, E. P., et al. (2025) · Journal of Clinical Investigation · doi:10.1172/jci186065 · Cited by 11

Cx32 promotes autophagy and produces resistance to SN‑induced apoptosis via activation of AMPK signalling in cervical cancer

Fan, L.-X., Tao, L., Lai, Y., Cai, S., Zhao, Z., Yang, F., Su, R., & Wang, Q. (2021) · International Journal of Oncology · doi:10.3892/ijo.2021.5300 · Cited by 10

Drosophila D-idua Reduction Mimics Mucopolysaccharidosis Type I Disease-Related Phenotypes

Filippis, C. D., Napoli, B., Rigon, L., et al. (2021) · Cells · doi:10.3390/cells11010129 · Cited by 9

Nanoparticle-Mediated Therapy with miR-198 Sensitizes Pancreatic Cancer to Gemcitabine Treatment through Downregulation of VCP-Mediated Autophagy

Marín‐Müller, C., Li, D., Lü, J., Liang, Z., Vega-Martínez, O., Crawford, S. E., Estes, M. K., Fisher, W. E., Chen, C., & Yao, Q. C. (2023) · Pharmaceutics · doi:10.3390/pharmaceutics15082038 · Cited by 10

Autophagy markers are decreased in bone of osteoporotic patients: a monocentric comparative study

Trojani, M.-C., Clavé, A., Bereder, I., Camuzard, O., de Dompsure, R. B., Gonzalez, J., Trojani, C., Santucci‐Darmanin, S., Carle, G. F., Breuil, V., et al. (2024) · European Journal of Endocrinology · doi:10.1093/ejendo/lvae017 · Cited by 11

Advances in research on autophagy mechanisms in resistance to endometrial cancer treatment

Ji, J., Cheng, X., Du, R., Xie, Y., & Zhang, Y. (2024) · Frontiers in Oncology · doi:10.3389/fonc.2024.1364070 · Cited by 9

Traumatic brain injury heterogeneity affects cell death and autophagy

McDonald, B. Z., Tarudji, A. W., Zhang, H., Ryu, S., Eskridge, K. M., & Kievit, F. M. (2024) · Experimental Brain Research · doi:10.1007/s00221-024-06856-1 · Cited by 9

SPRED2 Is a Novel Regulator of Autophagy in Hepatocellular Carcinoma Cells and Normal Hepatocytes

Wang, T., Gao, T., Fujisawa, M., Ohara, T., Sakaguchi, M., Yoshimura, T., & Matsukawa, A. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25116269 · Cited by 10

Effect of Golgi phosphoprotein 2 (GOLPH2/GP73) on autophagy in human hepatocellular carcinoma HepG2 cells

Zhou, Y., Jiang, J., You, J., & Zhou, L. (2014) · Tumor Biology · doi:10.1007/s13277-014-2974-x · Cited by 9

SNARE mediates autophagosome–lysosome fusion

Furuta, N., & Amano, A. (2012) · Journal of Oral Biosciences · doi:10.1016/j.job.2012.03.001 · Cited by 9

Resistance wheel exercise from mid-life has minimal effect on sciatic nerves from old mice in which sarcopenia was prevented

Krishnan, V. S., White, Z. R., Terrill, J. R., Hodgetts, S. I., Fitzgerald, M., Shavlakadze, T., Harvey, A. R., & Grounds, M. D. (2017) · Biogerontology · doi:10.1007/s10522-017-9714-8 · Cited by 9

Imidazolines increase the levels of the autophagosomal marker LC3-II in macrophage-like RAW264.7 cells

Nakagawa, S., Ueno, T., Manabe, T., & Kawasaki, K. (2018) · Canadian Journal of Physiology and Pharmacology · doi:10.1139/cjpp-2018-0021 · Cited by 9

Curative effect of xanthohumol supplementation during liver fluke-associated cholangiocarcinogenesis: Potential involvement of autophagy

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