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Phage treatment of human infections

Open access
Abedon, Stephen T., Kuhl, Sarah J., Blasdel, Bob G., Kutter, Elizabeth Martin·2011·Bacteriophage

Abstract

Phages as bactericidal agents have been employed for 90 years as a means of treating bacterial infections in humans as well as other species, a process known as phage therapy. In this review we explore both the early historical and more modern use of phages to treat human infections. We discuss in particular the little-reviewed French early work, along with the Polish, US, Georgian and Russian historical experiences. We also cover other, more modern examples of phage therapy of humans as differentiated in terms of disease. In addition, we provide discussions of phage safety, other aspects of phage therapy pharmacology, and the idea of phage use as probiotics.

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Crossref · 10.4161/bact.1.2.15845

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Metadata

Authors
Abedon, S. T., Kuhl, S. J., Blasdel, B. G., & Kutter, E. M.
Venue
Bacteriophage
Published
2011-03
Volume
1
Issue
2
Pages
66-85
ISSN
  • 2159-7073 (ISSN-L)
  • 2159-7081
OpenAlex
W1991772704
Cited by
980
References
0
FWCI
26.10
Type
journal article
Language
en
Open access
green

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.