The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Search for inhibitors of endocytosis: Intended specificity and unintended consequences
Open accessAbstract
We discuss here the variety of approaches that have been taken to inhibit different forms of endocytosis. Typically, both non-specific and specific chemical inhibitors of endocytosis are tried in order to "classify" entry of a new plasma membrane protein into one of the various types of endocytosis. This classification can be confirmed through genetic approaches of protein depletion or overexpression of mutants of known endocytosis machinery components. Although some new compounds have been designed to be selective in biochemical assays, we caution investigators to be alert to the unintended consequences that sometimes arise when these compounds are applied to intact cells.
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Cites
Molecular mechanism and physiological functions of clathrin-mediated endocytosis
McMahon, H. T., & Boucrot, E. (2011) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm3151 · Cited by 2,223
Shaping cups into phagosomes and macropinosomes
Swanson, J. A. (2008) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2447 · Cited by 941
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Metadata
- Authors
- Dutta, D., & Donaldson, J. G.
- Venue
- Cellular Logistics
- Publisher
- Informa UK Limited
- Published
- 2012-10
- Volume
- 2
- Issue
- 4
- Pages
- 203-208
- ISSN
- 2159-2780 (ISSN-L)
- 2159-2799
- OpenAlex
- W2047247630
- Cited by
- 435
- References
- 2
- FWCI
- 3.36
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- Dutta, D., & Donaldson, J. G. (2012). Search for inhibitors of endocytosis: Intended specificity and unintended consequences. Cellular Logistics. https://doi.org/10.4161/cl.23967
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