Passive immunization for the public health control of communicable diseases: Current status in four high-income countries and where to next
Open accessAbstract
The practice of passive immunization with human immune globulin (IG) for the control of communicable diseases (measles, rubella and hepatitis A) differs somewhat between Australia, the United States of America, the United Kingdom, and New Zealand despite the many similarities of these countries, including disease incidence rates and population immunity. No minimum effective dose of IG has been identified for protecting susceptible contacts of measles or hepatitis A. Recommended passive immunization practice for susceptible pregnant contacts of rubella is based on limited evidence in all countries. We suggest that gaps in the evidence base need to be addressed to appropriately inform the role of passive immunization in public health practice into the future.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Specific neutralizing antibodies purified from immune donors can prevent the transmission of varicella zoster virus, hepatitis B virus and measles virus.
“the use of specific neutralizing antibodies purified from immune donors to prevent the transmission of various viruses, including varicella zoster virus, HBV and measles virus29.”
From A guide to vaccinology: from basic principles to new developments (2021) · cites this paper as [29]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
Fiore, A. E., Uyeki, T. M., Broder, K. R., Finelli, L., Euler, G. L., Singleton, J. A., Iskander, J. K., Wortley, P. M., Shay, D. K., Bresee, J., et al. (2009) · PubMed · Cited by 1,964 · see citing works
Summary of notifiable diseases--United States, 2012.
Adams, D. A., Jajosky, R. A., Ajani, U. A., Kriseman, J., Sharp, P., Onwen, D. H., Schley, A. W., Anderson, W. J., Grigoryan, A., Aranas, A. E., et al. (2014) · PubMed · Cited by 1,342 · see citing works
Fiore, A. E., Wasley, A., & Bell, B. P. (1999) · PsycEXTRA Dataset · doi:10.1037/e547812006-001 · Cited by 1,130 · see citing works
Antibodies, viruses and vaccines
Burton, D. R. (2002) · Nature Reviews Immunology · doi:10.1038/nri891 · Cited by 637 · see citing works
Watson, J., Hadler, S. C., Dykewicz, C. A., Reef, S. E., & Phillips, L. (1998) · PsycEXTRA Dataset · doi:10.1037/e547712006-001 · Cited by 584 · see citing works
Hepatitis A virus seroprevalence by age and world region, 1990 and 2005
Jacobsen, K. H., & Wiersma, S. (2010) · Vaccine · doi:10.1016/j.vaccine.2010.08.037 · Cited by 570 · see citing works
Epidemiology of Hepatitis B and C Viruses: A Global Overview
Te, H. S., & Jensen, D. M. (2010) · Clinics in Liver Disease · doi:10.1016/j.cld.2009.11.009 · Cited by 480 · see citing works
Burnouf, T. (2007) · Transfusion Medicine Reviews · doi:10.1016/j.tmrv.2006.11.001 · Cited by 286 · see citing works
Hepatitis A Vaccine versus Immune Globulin for Postexposure Prophylaxis
Victor, J. C., Monto, A. S., Surdina, T. Y., Suleimenova, S. Z., Vaughan, G., Nainan, O. V., Favorov, M. O., Margolis, H. S., & Bell, B. P. (2007) · New England Journal of Medicine · doi:10.1056/nejmoa070546 · Cited by 239 · see citing works
History of Immunoglobulin Replacement
Eibl, M. M. (2008) · Immunology and Allergy Clinics of North America · doi:10.1016/j.iac.2008.06.004 · Cited by 126 · see citing works
Neutralization of animal virus infectivity by antibody
Reading, S. A., & Dimmock, N. J. (2007) · Archives of Virology · doi:10.1007/s00705-006-0923-8 · Cited by 105 · see citing works
Dayan, G. H., Ortega‐Sanchez, I. R., LeBaron, C. W., Quinlisk, M. P., & and the Iowa Measles Response Team (2005) · PEDIATRICS · doi:10.1542/peds.2004-2512 · Cited by 101 · see citing works
Seroprevalence of Measles Antibody in the US Population, 1999–2004
McQuillan, G. M., Kruszon‐Moran, D., Hyde, T. B., Forghani, B., Bellini, W. J., & Dayan, G. H. (2007) · The Journal of Infectious Diseases · doi:10.1086/522866 · Cited by 82 · see citing works
COMPARISON OF TWO LOTS OF IMMUNE SERUM GLOBULIN FOR PROPHYLAXIS OF INFECTIOUS HEPATITIS1
Mosley, J. W., Reisler, D. M., Brachott, D., ROTH, D., & WEISER, J. (1968) · American Journal of Epidemiology · doi:10.1093/oxfordjournals.aje.a120845 · Cited by 80 · see citing works
Vyse, A., Gay, N., Hesketh, L. M., Pebody, R. G., Morgan-Capner, P., & Miller, E. (2006) · Epidemiology and Infection · doi:10.1017/s0950268806006340 · Cited by 77 · see citing works
The seroepidemiology of rubella in western Europe
Pebody, R. G., Edmunds, W. J., Spaendonck, M. C., Olin, P., BERBERS, G., Rebière, I., Lecœur, H., Crovari, P., Davidkin, I., Gabutti, G., et al. (2000) · Epidemiology and Infection · doi:10.1017/s0950268899004574 · Cited by 68 · see citing works
Impact of the Australian Measles Control Campaign on immunity to measles and rubella
Gilbert, G. L., Escott, R., Gidding, H. F., Turnbull, F., Heath, T. C., McIntyre, P. B., & Burgess, M. A. (2001) · Epidemiology and Infection · doi:10.1017/s0950268801005830 · Cited by 67 · see citing works
CONVALESCENT WHOLE BLOOD, PLASMA AND SERUM IN PROPHYLAXIS OF MEASLES
Zingher, A. (1924) · JAMA · doi:10.1001/jama.1924.02650410022011 · Cited by 60 · see citing works
Current efficacy of postexposure prophylaxis against measles with immunoglobulin
Endo, A., Izumi, H., Miyashita, M., Taniguchi, K., Okubo, O., & Harada, K. (2001) · The Journal of Pediatrics · doi:10.1067/mpd.2001.113710 · Cited by 57 · see citing works
Klevens, R. M., Kruszon‐Moran, D., Wasley, A., Gallagher, K., McQuillan, G. M., Kuhnert, W. L., Teshale, E. H., Drobeniuc, J., & Bell, B. P. (2011) · Public Health Reports · doi:10.1177/003335491112600408 · Cited by 55 · see citing works
Hyde, T. B., Kruszon‐Moran, D., McQuillan, G. M., Cossen, C. K., Forghani, B., & Reef, S. E. (2006) · Clinical Infectious Diseases · doi:10.1086/505947 · Cited by 53 · see citing works
Titered Lots of Immune Globulin (Ig)
Schiff, G. M. (1969) · American journal of diseases of children · doi:10.1001/archpedi.1969.02100040324029 · Cited by 49 · see citing works
Antibodies against viruses: passive and active immunization
Law, M., & Hangartner, L. (2008) · Current Opinion in Immunology · doi:10.1016/j.coi.2008.06.005 · Cited by 48 · see citing works
Sustained measles elimination in Australia and priorities for long term maintenance
Gidding, H. F., Wood, J., MacIntyre, C. R., Kelly, H. A., Lambert, S. B., Gilbert, G. L., & McIntyre, P. B. (2007) · Vaccine · doi:10.1016/j.vaccine.2007.01.090 · Cited by 48 · see citing works
Summary of notifiable diseases: United States, 2009.
(2011) · PubMed · Cited by 48 · see citing works
Pavia, A. T., NIELSEN, L., ARMINGTON, L., Thurman, D. J., Tierney, E. F., & NICHOLS, C. R. (1990) · American Journal of Epidemiology · doi:10.1093/oxfordjournals.aje.a115601 · Cited by 43 · see citing works
Immunoglobulins for preventing hepatitis A
Liu, J., Nikolova, D., & Fei, Y. (2009) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd004181.pub2 · Cited by 35 · see citing works
Convalescent whole blood, plasma and serum in the prophylaxis of measles
Zingher, A., & Mortimer, P. (2005) · Reviews in Medical Virology · doi:10.1002/rmv.480 · Cited by 33 · see citing works
Studies of Rubella and Its Prevention With Immune Globulin
Doege, T. C. (1967) · JAMA · doi:10.1001/jama.1967.03120200062008 · Cited by 32 · see citing works
Hepatitis A epidemiology in Australia: national seroprevalence and notifications
Amin, J., Gilbert, G. L., Escott, R., Heath, T. C., & Burgess, M. A. (2001) · The Medical Journal of Australia · doi:10.5694/j.1326-5377.2001.tb143309.x · Cited by 32 · see citing works
Rabenau, H. F., Marianov, B., Wicker, S., & Allwinn, R. (2007) · Medical Microbiology and Immunology · doi:10.1007/s00430-007-0037-2 · Cited by 30 · see citing works
The effectiveness of prophylaxis for measles contacts in NSW
Sheppeard, V. K., Forssman, B. L., Ferson, M. J., Moreira, C., Campbell‐Lloyd, S., Dwyer, D. E., & McAnulty, J. (2009) · New South Wales Public Health Bulletin · doi:10.1071/nb08014 · Cited by 30 · see citing works
The changing epidemiological pattern of hepatitis A in England and Wales
Morris, M. C., Gay, N. J., Hesketh, L. M., Morgan-Capner, P., & Miller, E. (2002) · Epidemiology and Infection · doi:10.1017/s095026880200701x · Cited by 25 · see citing works
Toward rubella elimination in Europe: An epidemiological assessment
Muscat, M., Zimmerman, L., Bacci, S., Bang, H., Glismann, S., Mølbak, K., & Reef, S. E. (2011) · Vaccine · doi:10.1016/j.vaccine.2011.12.016 · Cited by 25 · see citing works
Assessment of British Gammaglobulin in Preventing Infectious Hepatitis
(1968) · BMJ · doi:10.1136/bmj.3.5616.451 · Cited by 21 · see citing works
Kelly, H. A., & Karapanagiotidis, T. (2004) · Communicable Diseases Intelligence · doi:10.33321/cdi.2004.28.3 · Cited by 18 · see citing works
Passive immunization: the forgotten arm of immunologically based strategies for disease containment
Gonik, B. (2011) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2011.06.076 · Cited by 17 · see citing works
Bianco, E., MASI, S. D., Mele, A., & Jefferson, T. (2004) · Digestive and Liver Disease · doi:10.1016/j.dld.2004.07.014 · Cited by 12 · see citing works
The prevalence of viral hepatitis (HAV, HBV and HCV) in the Christchurch community.
CHAPMAN, B. A., Burt, M. J., Frampton, C., Collett, J. A., Yeo, K.-H., Wilkinson, I. D., Cook, H. B., Barclay, M., Ross, A. G., & George, P. (2000) · PubMed · Cited by 11 · see citing works
Gillis, D., Yetiv, N., Gdalevich, M., Mimouni, D., Ashkenazi, I., Shpilberg, O., Eldad, A., & Shemer, J. (2000) · Vaccine · doi:10.1016/s0264-410x(00)00091-8 · Cited by 11 · see citing works
THE RISK OF ACQUIRING HEPATITIS FROM SEWAGE-CONTAMINATED WATER
Rosenberg, M. L., Koplan, J. P., & Pollard, R. A. (1980) · American Journal of Epidemiology · doi:10.1093/oxfordjournals.aje.a112971 · Cited by 11 · see citing works
The efficacy of gamma globulin in the prevention of German measles.
BASS, M. H., & Hb, D. (1949) · PubMed · Cited by 10 · see citing works
The costs of containing measles within a health care service
Stuart, R. L., Bradford, J., Leszkiewicz, P., Wilson, J. K., & Gillespie, E. E. (2010) · Healthcare Infection · doi:10.1071/hi10008 · Cited by 8 · see citing works
Neumann‐Haefelin, D., Neumann-Haefelin, C., Petersen, E., Luthardt, T., & Haas, R. (1975) · DMW - Deutsche Medizinische Wochenschrift · doi:10.1055/s-0028-1106191 · Cited by 8 · see citing works
Experimental studies with rubella: Evaluation of gamma globulin for prophylaxis
Green, R. H., Balsamo, M. R., Giles, J. P., D, S. K. M., & Mirick, G. S. (1965) · Archives of Virology · doi:10.1007/bf01253868 · Cited by 7 · see citing works
Egoz, N. (1986) · PubMed · Cited by 7 · see citing works
Rötelninfektion in der Schwangerschaft
Petersen, E., Neumann‐Haefelin, D., & Heußler, M. (1978) · DMW - Deutsche Medizinische Wochenschrift · doi:10.1055/s-0028-1129325 · Cited by 5 · see citing works
Passive immunization with gamma globulin.
Tj, M. (1966) · PubMed · Cited by 4 · see citing works
Prevention of rubella malformations.
(1968) · BMJ · doi:10.1136/bmj.3.5612.199 · Cited by 2 · see citing works
(1967) · BMJ · doi:10.1136/bmj.4.5573.183 · Cited by 2 · see citing works
The efficacy of gamma globulin in the prevention of measles.
Ws, H., Tayback, M., & Williams, H. V. (1957) · PubMed · Cited by 1 · see citing works
(1967) · PubMed Central · Cited by 1 · see citing works
Flagged first, then by citations
Research works printed but not linked: 9
- Jacobsen K. The Global Prevalence of Hepatitis A Virus Infection and Susceptibility: A Systematic Review. Geneva: Immunization, Vaccines and Biologicals, World Health Organization, 2009.
- UK Department of Health. Chapter 17: Hepatitis A -updated 9 February 2011. Immunization against infectious disease -"The Green Book" -2006 updated edition. UK: Department of Health, UK, 2011.
- UK Department of Health. Chapter 28: Rubella -file replaced 14 December 2010. Immunization against infectious disease -"The Green Book" -2006 updated edition. UK: Department of Health, UK, 2010.
- Australian Technical Advisory Group on Immunization. The Australian Immunization Handbook 10th edition. Canberra: Commonwealth of Australia, 2013.
- Recommended immunization schedules for persons aged 0-18 years -United States, 2012. MMWR Morb Mortal Wkly Rep 2012; 61:1-4 References
- Dayan G, Rota J, Bellini W, Redd S. Chapter 7: Measles. In: Roush S, McIntyre L, Baldy L, eds. Manual for the Surveillance of Vaccine-Preventable Diseases. Atlanta, USA: Centers for Disease Control and Prevention, 2008.
- Australian Technical Advisory Group on Immunization. The Australian Immunization handbook 9th edition. Canberra: Australian Government, 2008.
- Poutasi K. Re: Review of Australia's Plasma Fractionation Arrangements. 2006.
- Waagner D. Childhood exanthems. In: Kaplan S, ed. Current Therapy in Pediatric Infectious Diseases. Saint Louis: Mosby-Year Book, Inc., 1993:274-8.
Cited by
Sorted by citations
A guide to vaccinology: from basic principles to new developments
Pollard, A. J., & Bijker, E. M. (2021) · Nature Reviews Immunology · doi:10.1038/s41577-020-00479-7 · Cited by 1,593 · see citing works
Irani, V., Guy, A. J., Andrew, D. W., Beeson, J. G., Ramsland, P. A., & Richards, J. S. (2015) · Molecular Immunology · doi:10.1016/j.molimm.2015.03.255 · Cited by 290 · see citing works
Aliprantis, A. O., Wolford, D. G., Caro, L., Maas, B. M., Ma, H., Montgomery, D. L., Sterling, L. M., Hunt, A., Cox, K. S., Vora, K. A., et al. (2020) · Clinical Pharmacology in Drug Development · doi:10.1002/cpdd.883 · Cited by 67 · see citing works
Matysiak‐Klose, D., Santibanez, S., Schwerdtfeger, C., Koch, J., von Bernuth, H., Hengel, H., Littmann, M., Terhardt, M., Wicker, S., Mankertz, A., et al. (2018) · Vaccine · doi:10.1016/j.vaccine.2018.10.070 · Cited by 24 · see citing works
Young, M. K. (2019) · Human Vaccines & Immunotherapeutics · doi:10.1080/21645515.2019.1621148 · Cited by 24 · see citing works
Self-citationViral Hepatitis - The Road Traveled and the Journey Remaining
Ghulam, F., Zakaria, N., Majeed, M. I., & Ismail, F. (2022) · Hepatic Medicine Evidence and Research · doi:10.2147/hmer.s352568 · Cited by 18 · see citing works
Do Australian immunoglobulin products meet international measles antibody titer standards?
Young, M. K., Bertolini, J., Kotharu, P., Maher, D. W., & Cripps, A. W. (2016) · Human Vaccines & Immunotherapeutics · doi:10.1080/21645515.2016.1234554 · Cited by 12 · see citing works
Self-citationYoung, M. K., Ng, S., Nimmo, G. R., & Cripps, A. W. (2018) · Expert Opinion on Drug Metabolism & Toxicology · doi:10.1080/17425255.2018.1484449 · Cited by 7 · see citing works
Self-citationLuca, V. D., Giovannuzzi, S., Capasso, C., & Supuran, C. T. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms252212291 · Cited by 5 · see citing works
Luca, V. D., Giovannuzzi, S., Supuran, C. T., & Capasso, C. (2024) · Journal of Enzyme Inhibition and Medicinal Chemistry · doi:10.1080/14756366.2024.2372731 · Cited by 3 · see citing works
EVALUATION AND MANAGEMENT OF EXPOSURE TO INFECTIOUS AGENTS
Macher, J. M., Gold, D., Cruz, P., Kyle, J. L., Durrani, T. S., & Shusterman, D. J. (2019) · Wiley eBooks · doi:10.1002/9781119581482.ch6 · Cited by 4 · see citing works
Vaccination post-exposition : mise au point
Canouï, É., & Launay, O. (2017) · Journal des Anti-infectieux · doi:10.1016/j.antinf.2017.04.001
Impfungen für das Immungedächtnis – immer wieder oder einmalig?
Lehmann, C. (2022) · Der Internist · doi:10.1007/s00108-022-01324-w
Exploring the Efficacy of Convalescent Plasma Therapy in COVID-19 Patients: A Clinical Trial Study
Mahi‐Birjand, M., Ziaee, M., Alemzadeh, E., Barkhordari, A., Azarkar, Z., Ebrahimzadeh, A., Abedi, F., & Azarkar, G. (2024) · Coronaviruses · doi:10.2174/0126667975307584240927114217
Paes, B. A., Manzoni, P., Fullarton, J., Rodgers‐Gray, B. S., & Carbonell-Estrany, X. (2026) · Vaccines · doi:10.3390/vaccines14070556
Evaluation and Management of Exposure to Infectious Agents
Cruz, P., Kyle, J. L., Gold, D., Armour, P., & Durrani, T. S. (2026) · doi:10.1002/9781394319947.ch7
- Authors
- Young, M. K., & Cripps, A. W.
- Affiliations
- Griffith University (AU)
- Corresponding author
- Young, Megan K
- Venue
- Human Vaccines & Immunotherapeutics
- Publisher
- Informa UK Limited
- Published
- 2013-09-19
- Volume
- 9
- Issue
- 9
- Pages
- 1885-1893
- ISSN
- 2164-5515 (ISSN-L)
- 2164-554X
- PMC
- PMC3906352
- OpenAlex
- W1975550815
- Cited by
- 16
- References
- 53
- Citations by year
- 2026: 2 · 2024: 3 · 2022: 2 · 2020: 2 · 2019: 2 · 2018: 2 · 2017: 1 · 2016: 1 · 2015: 1
- FWCI
- 0.08
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Human Vaccines & Immunotherapeutics (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Griffith Research Online (submittedVersion)
- Topics
- Health Sciences › Medicine › Epidemiology › Virology and Viral Diseases
- Life Sciences › Immunology and Microbiology › Microbiology › Bacterial Infections and Vaccines
- Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Monoclonal and Polyclonal Antibodies Research
- Keywords
- passive immunization, human immunoglobulin, measles, rubella, hepatitis A, contact tracing, evidence gaps, high-income countries
- MeSH terms
- Australia, United Kingdom, Hepatitis A, Humans, Immunoglobulin G, Immunization, Passive, Measles, New Zealand, Rubella, United States, Developed Countries
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
