The DOI matches its Crossref record; 145 of the 145 references it cites were found in a registry or an index.
Japanese encephalitis: The virus and vaccines
Open accessAbstract
Japanese encephalitis (JE) is an infectious disease of the central nervous system caused by Japanese encephalitis virus (JEV), a zoonotic mosquito-borne flavivirus. JEV is prevalent in much of Asia and the Western Pacific, with over 4 billion people living at risk of infection. In the absence of antiviral intervention, vaccination is the only strategy to develop long-term sustainable protection against JEV infection. Over the past half-century, a mouse brain-derived inactivated vaccine has been used internationally for active immunization. To date, however, JEV is still a clinically important, emerging, and re-emerging human pathogen of global significance. In recent years, production of the mouse brain-derived vaccine has been discontinued, but 3 new cell culture-derived vaccines are available in various parts of the world. Here we review current aspects of JEV biology, summarize the 4 types of JEV vaccine, and discuss the potential of an infectious JEV cDNA technology for future vaccine development.
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Cites
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A structural perspective of the flavivirus life cycle
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Structure of the dengue virus envelope protein after membrane fusion
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Estimated global incidence of Japanese encephalitis:
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Cited by
mRNA Vaccines against Flaviviruses
Wollner, C. J., & Richner, J. M. (2021) · Vaccines · doi:10.3390/vaccines9020148 · Cited by 44
Metadata
- Authors
- Yun, S.-I., & Lee, Y.-M.
- Venue
- Human Vaccines & Immunotherapeutics
- Publisher
- Informa UK Limited
- Published
- 2013-10-25
- Volume
- 10
- Issue
- 2
- Pages
- 263-279
- ISSN
- 2164-5515 (ISSN-L)
- 2164-554X
- OpenAlex
- W2038220721
- Cited by
- 288
- References
- 145
- FWCI
- 11.66
- Type
- journal article
- Language
- en
- Open access
- bronze
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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