The DOI matches its Crossref record; 25 of the 25 references it cites were found in a registry or an index.
Bone grafts, bone substitutes and orthobiologics: The bridge between basic science and clinical advancements in fracture healing
Open accessAbstract
The biology of fracture healing is better understood than ever before, with advancements such as the locking screw leading to more predictable and less eventful osseous healing. However, at times one's intrinsic biological response, and even concurrent surgical stabilization, is inadequate. In hopes of facilitating osseous union, bone grafts, bone substitutes and orthobiologics are being relied on more than ever before. The osteoinductive, osteoconductive and osteogenic properties of these substrates have been elucidated in the basic science literature and validated in clinical orthopaedic practice. Furthermore, an industry built around these items is more successful and in demand than ever before. This review provides a comprehensive overview of the basic science, clinical utility and economics of bone grafts, bone substitutes and orthobiologics.
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Cites
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Cited by
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Metadata
- Authors
- Roberts, T. T., & Rosenbaum, A. J.
- Venue
- Organogenesis
- Publisher
- Informa UK Limited
- Published
- 2012-10
- Volume
- 8
- Issue
- 4
- Pages
- 114-124
- ISSN
- 1547-6278 (ISSN-L)
- 1555-8592
- OpenAlex
- W1998727589
- Cited by
- 773
- References
- 25
- FWCI
- 2.79
- Type
- journal article
- Language
- en
- Open access
- bronze
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- CoChat. (2026). Citation check: Bone grafts, bone substitutes and orthobiologics: The bridge between basic science and clinical advancements in fracture healing. https://app.cochat.ai/papers/10.4161/org.23306
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- Roberts, T. T., & Rosenbaum, A. J. (2012). Bone grafts, bone substitutes and orthobiologics: The bridge between basic science and clinical advancements in fracture healing. Organogenesis. https://doi.org/10.4161/org.23306
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
