The DOI matches its Crossref record; 48 of the 48 references it cites were found in a registry or an index.
VEGF and endothelial guidance in angiogenic sprouting
Open accessAbstract
The cellular actions of VEGF need to be coordinated to guide vascular patterning during sprouting angiogenesis. Individual endothelial tip cells lead and guide the blood vessel sprout, while neighbouring stalk cells proliferate and form the vascular lumen. Recent studies illustrate how endothelial DLL4/NOTCH signalling, stimulated by VEGF, regulates the sprouting response by limiting tip cell formation in the stalk. The spatial distribution of VEGF, in turn, regulates the shape of the ensuing sprout by directing tip cell migration and determining stalk cell proliferation.
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Cites
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Astrocyte-endothelial interactions at the blood-brain barrier
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VEGF guides angiogenic sprouting utilizing endothelial tip cell filopodia
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Self-citationA presenilin-1-dependent γ-secretase-like protease mediates release of Notch intracellular domain
De Strooper, B., Annaert, W., Cupers, P., Saftig, P., Craessaerts, K., Mumm, J. S., Schroeter, E. H., Schrijvers, V., Wolfe, M. S., Ray, W. J., et al. (1999) · Nature · doi:10.1038/19083 · Cited by 2,100
Dll4 signalling through Notch1 regulates formation of tip cells during angiogenesis
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HES and HERP families: Multiple effectors of the notch signaling pathway
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Blockade of Dll4 inhibits tumour growth by promoting non-productive angiogenesis
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Cited by
VEGF in signaling and disease: beyond discovery and development
Apte, R. S., Chen, D. S., & Ferrara, N. (2019) · Cell · doi:10.1016/j.cell.2019.01.021 · Cited by 2,721
Collective cell migration in morphogenesis, regeneration and cancer
Friedl, P., & Gilmour, D. (2009) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2720 · Cited by 2,712
In vitro cell migration and invasion assays
Kramer, N., Walzl, A., Unger, C., Rosner, M., Krupitza, G., Hengstschläger, M., & Dolznig, H. (2013) · Mutation Research/Reviews in Mutation Research · doi:10.1016/j.mrrev.2012.08.001 · Cited by 1,170
Vascularization and Angiogenesis in Tissue Engineering: Beyond Creating Static Networks
Rouwkema, J., & Khademhosseini, A. (2016) · Trends in Biotechnology · doi:10.1016/j.tibtech.2016.03.002 · Cited by 651
Endothelial von Willebrand factor regulates angiogenesis
Starke, R. D., Ferraro, F., Paschalaki, K. E., Dryden, N. H., McKinnon, T. A. J., Sutton, R. E., Payne, E. M., Haskard, D. O., Hughes, A. D., Cutler, D. F., et al. (2011) · Blood · doi:10.1182/blood-2010-01-264507 · Cited by 512
Metadata
- Authors
- Gerhardt, H.
- Venue
- Organogenesis
- Publisher
- Informa UK Limited
- Published
- 2008-10
- Volume
- 4
- Issue
- 4
- Pages
- 241-246
- ISSN
- 1547-6278 (ISSN-L)
- 1555-8592
- OpenAlex
- W2034957927
- Cited by
- 318
- References
- 48
- FWCI
- 6.45
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Gerhardt, H. (2008). VEGF and endothelial guidance in angiogenic sprouting. Organogenesis. https://doi.org/10.4161/org.4.4.7414
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
